INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2019
·
IF 3.375
Menghui Yan,Fang Jin,Yigang Ding,Guiying Wu,Rong Chen,Luhui Wang,Yuanzhi Yan
A novel titanosilicate zeolite was synthesized by a sequential treatment of ERB-1 with deboronation and atom-planting method to develop an epoxide catalyst. The Fourier transform infrared (FTIR) and the diffuse reflectance infrared Fourier transform (DRIFT) characteristic results reveal that the silanol hydroxyl nests generated by deboronation process are further consumed by the dehydrochlorination of TiCl4 during the atom-planting treatment. At the same time, the titanium species are incorporated into the framework of MWW structure. The energy-dispersive spectroscopy (EDS), ultraviolet-visible light (UV-vis), and ultraviolet resonance Raman spectroscopy (UVRRS) characterization results reveal that the amount and coordination states of the incorporated Ti species can be controlled by the atom-planting treatment time and temperature. The catalytic performance of the new titanosilicates in the epoxidation of 1-hexene with H2O2 and of cyclohexene with tert-butyl hydroperoxide is compared for the efficiency of Ti species in the hydrophilic and hydrophobic system. The catalytic results show the framework tetrahedral coordinated titanium species are more efficient for epoxidation than extra-framework octahedral Ti species.
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ANALYTICA CHIMICA ACTA
·
2019
·
IF 5.256
Jiaxin Zheng,Xiaolun Peng,Yijia Wang,Ting Bao,Wei Wen,Xiuhua Zhang,Shengfu Wang
The development of some sensitive methods for MUC1 is critical for preclinical diagnosis of tumors. In this experiment, we built a triple-amplified electrochemical aptasensor to achieve sensitive detection of MUC1, which was based on exonuclease III (Exo III)-assisted with strand displacement reaction and enzyme catalytic strategy. Firstly, with the help of Exo III, MUC1 and aptamer could be recycled during the cycle I, the single stranded DNA-1 (S-1) was produced during the process and was introduced to the hybride reaction on the electrode. Secondly, during the cycle II, strand displacement reaction was triggered on the electrode with the adding of hairpin DNA-2 (H-2). Thirdly, after the gold nanoparticles (AuNPs)-DNA-enzyme conjugates hybrided with the H-2 on the electrode, the AuNPs-DNA-enzyme conjugates could act as signal probe to produce electrochemical catalytic signal. We used the fabricated triple-amplified electrochemical aptasensor that could detect MUC1 from 0.1 pg mL −1 to 10 ng mL −1 with the detection limit of 0.04 pg mL −1 under the optimized experimental conditions. The constructed triple-amplified electrochemical aptasensor could be applied in real samples determination. Besides, the strategy can be applied to detect other proteins for health monitoring.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2019
·
IF 3.375
Jian Zhang,Liang Wang,Zhiyi Wu,Hai Wang,Chengtao Wang,Shichao Han,Feng-Shou Xiao
We report the synthesis of Zn/ZSM-5 particles coated with a silicalite-1 zeolite shell (core–shell Zn/ZSM-5@silicalite-1) via grinding of the raw silica source materials with TPAOH and Zn/ZSM-5, followed by solvent-free crystallization at 180 °C for 72 h. The product was well characterized by the XRD patterns, N2 sorption isotherms, SEM images, and TEM images. Because of the core–shell structure, the Zn/ZSM-5@silicalite-1 sample exhibits high selectivities for benzene, toluene, and xylenes in the conversion of methanol, compared with those over ZSM-5 and Zn/ZSM-5 samples. The solvent-free synthesis offers an alternative method for preparing core–shell Zn/ZSM-5@silicalite-1 catalysts.
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Asian Journal of Pharmaceutical Sciences
·
2018
·
IF 4.56
Shilei Yang,Zhihao Liu,Changyuan Wang,Shijie Wen,Qiang Meng,Xiaokui Huo,Huijun Sun,Xiaodong Ma,Jinyong Peng,Zhonggui He,Kexin Liu
To assess the mechanism of the pharmacokinetic interaction between piperacillin and tazobactam , renal excretion and pharmacokinetic studies of piperacillin/tazobactam were investigated in normal and bacteremia rats. A bacteremia model was established to investigate the pharmacokinetic properties of piperacillin and tazobactam under different conditions. Renal slices were taken to examine the uptake of piperacillin and tazobactam. Pharmacokinetic studies of β-lactamase in rats were performed to study the contribution of rOat1/3 to the inhibition of tazobactam on β-lactamase. The AUC (from 2.93 ± 0.58 to 6.52 ± 1.44 mg·min/ml) and the plasma clearance ( CL P ) (from 2.41 ± 1.20 to 0.961 ± 0.212 ml/min/kg) of tazobactam were both altered after the intravenous coadministration of piperacillin and tazobactam in the bacteremia rats. The renal clearance ( CL R ) of tazobactam decreased from 1.30 ± 0.50 to 0.361 ± 0.043 ml/min/kg. In summary, there was a beneficial interaction between piperacillin and tazobactam mediated by rOat1 and rOat3. Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through the inhibition of rOat1 and rOat3 in rats. The contribution rate of rOat1/3 for the synergistic effect was 20% when the two drugs were coadministered.
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BMC Veterinary Research
·
2019
·Vol. 15
·期 1
·1-12
·
IF 1.792
Du Hongxu,Bai Jingying,Wang Jinli,He Miao,Xiong Wen,Yuan Wenjuan,Qiao Mingyu,Ming Ke,Wu Yi,Wang Deyun,Hu Yuanliang,Liu Jiaguo
Background Duck viral hepatitis (DVH) is an acute disease of young ducklings with no effective veterinary drugs for treatment. Gynostemma pentaphyllum is a well-known traditional Chinese medicine that plays an important role in the treatment of various diseases. Gypenoside (GP), one of the main ingredients of Gynostemma pentaphyllum, was reported with good hepatoprotective effects. However, its low solubility limits its application in the clinics. To improve its solubility and bioactivity, a phosphorylated derivative of gypenoside (pGP) was prepared by the sodium trimetaphosphate-sodium tripolyphosphate (STMP-STPP) method. An infrared spectroscopy method was applied to analyse the structures of GP and pGP. Then, a methyl thiazolyl tetrazolium (MTT) colorimetric assay was applied to study the hepatocyte protective efficacy of these two drugs against duck hepatitis A virus type 1 (DHAV-1) infection, and qPCR, TUNEL labelling and flow cytometry methods were used to study the relevant hepatocyte protective in vitro.Results The infrared spectroscopy detection results showed that the phosphorylation modification of GP was successful. The MTT colorimetric assay results showed that both GP and pGP possessed good hepatocyte protective efficacy in vitro, and pGP performed better than GP when the drug was added before or after virus inoculation. Furthermore, the qPCR results revealed that both drugs could effectively inhibit the adsorption (when adding GP and pGP pre-virus inoculation), replication and release of DHAV-1, and the viral inhibition rate of pGP was greater than that of GP. The subsequent TUNEL labelling and flow cytometry assays showed that both GP and pGP could significantly inhibit duck embryo hepatocyte apoptosis induced by DHAV-1, and the inhibition effect of pGP was much stronger than that of GP.Conclusion sGP exerts good hepatocyte protective efficacy not only by inhibiting the proliferation of DHAV-1 but also by inhibiting duck embryonic hepatocyte apoptosis induced by DHAV-1, and phosphorylation modification significantly improves the antiviral and the anti-apoptotic effects of GP. Therefore, pGP has the potential to be developed into a novel drug against DHAV-1 infection.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2018
·Vol. 29
·期 11
·9613-9620
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IF 2.324
Zhang Jun,Kong Wenwen,Chang Aimin
The [Mn 1.56 Co 0.96 Ni 0.48 O 4 ] 1−x [SrMnO 3 ] x ((MCN) 1−x (SM) x , 0 ≤ x ≤ 0.5) ceramic thin composite films were grown on SiO 2 /Si (100) substrates by the chemical solution deposition (CSD) method. The results of X-ray diffraction showed that the (MCN) 1−x (SM) x (0 < x ≤ 0.5) films were a resemblance of the spinel–perovskite composite structure. The field emission scanning electron microscope analyses presented a considerable improvement in relative density with the increasing of the SM contents. In particular, the thermal constant of (MCN) 1−x (SM) x ceramic film increased from 3289 to 5390 K with the increasing of the SM contents (x) from 0 to 0.5. This feature was attributed to the increase in the grain boundary resistance and the increase in Mn 3+ /Mn 4+ pairs as the SM contents increased. From the spectroscopic ellipsometer spectroscopy results, it was found that the (MCN) 0.5 (SM) 0.5 film had the biggest refractive index n value of 2.36 at 1.5 eV and a strong absorption peak at 4.0 eV. The sensitivity of MCN spinel ceramic film was enhanced by the compounding of SM. It was a significant disposition in the study of negative temperature coefficient thermistors.
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APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
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2014
·Vol. 175
·期 5
·2647-2658
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IF 1.687
He Yu-Cai,Liu Feng,Zhang Dan-Ping,Gao Shan,Li Zhi-Qing,Tao Zhi-Cheng,Ma Cui-Luan
In this study, it was the first report that Bacillus sp. CCZU11-1 was used for the biotransformation of 1,3-propanediol cyclic sulfate (1,3-PDS) and its derivatives. The catalytic performance of Bacillus sp. sulfatase in the biotransformation of 1,3-PDS was significantly improved by biocatalyst permeabilization and immobilization. Using cell permeabilization, the hydrolytic activity of the whole-cell biocatalyst was increased by 3.5-fold after 1.5 h of pretreatment with 10 % ( v / v ) toluene at 30 °C and pH 7.0. Biotransformation of 20 mM 1,3-PDS for 24 h, 1,3-propanediol (1,3-PD) could be obtained in the yield of 97.4 % under the optimized reaction condition. Additionally, the immobilized biocatalysts, permeabilized cells entrapped in calcium alginate, and cross-linked enzyme aggregates were further employed to biotansform 1,3-PDS. Moreover, the total operational time of the immobilized biocatalysts could reach above 240 h with high conversion rate (>90 %).
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ADVANCED POWDER TECHNOLOGY
·
2014
·
IF 1.642
Renping Cao,Kangbin Chen,Qianglin Hu,Wensheng Li,Hui Ao,Chunyan Cao,Tao Liang
A series of Sr (1 − x − y − z ) MoO 4 : x Eu 3+ , y Bi 3+ , z R + (R + = Li + , Na + , and K + ) phosphors are prepared through solid-state reaction method in air. Eu 3+ doped SrMoO 4 phosphor can show red emission at ∼616 nm under excitation 275 nm and 397 nm light due to the 5 D 0 → 7 F 2 transition of Eu 3+ ion, and its emission intensity can be enhanced after co-doping Bi 3+ owing to energy transfer between Bi 3+ and Eu 3+ ions. The mechanism of energy transfer is discussed by the schematic energy level diagrams of Bi 3+ and Eu 3+ ions. The optimal composition in Eu 3+ and Bi 3+ co-doped SrMoO 4 phosphors is determined to be (Sr 0.92 Eu 0.05 Bi 0.03 )MoO 4 . The emission intensity of SrMoO 4 :Eu 3+ , Bi 3+ phosphor is found to be further improved by using Li + , Na + , and K + ions as charge compensators. These experiment results in the paper are helpful to develop novel and high-efficiency phosphors for white light-emitting diodes.
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OPTIK
·
2013
·
IF 0.524
Zhijuan Cao,Fengxian Qiu,Qing Wang,Guorong Cao,Lin Zhuang,Qiang Shen,Xiaolong Xu,Jie Wang,Qian Chen,Dongya Yang
The azo benzothiazole polyurethane–urea (ABPUU) was synthesized from chromophore molecule 4-[(6-nitrobenzothiazole-2-yl)diazenyl]phenyl-1,3-diamine NBDPD, polyether polyol (NJ-210) and isophorone diisocyanate (IPDI). The structure, thermal property , mechanical property and physical property were characterized and investigated. The refractive index ( n ) and thermo-optic coefficient (d n /d T ) of ABPUU was determined at different temperature and wavelength (532 nm, 650 nm and 850 nm) using attenuated total reflection (ATR) technique. Using the CCD digital imaging devices, transmission loss of ABPUU was measured. A 1 × 2 Y-branched and 2 × 2 Mach–Zehnder interferometer (MZI) switch with two rib waveguides , dual driving electrodes and two critical 3-dB couplers polymeric thermo-optic switches based on thermo-optic effect of prepared ABPUU were designed and simulation. The power consumption of the Y-branched switch is less than 0.84 mW. The Y-branched and MZI switching rising and falling times obtained are 0.8 ms and 0.2 ms, respectively.
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MATERIALS RESEARCH BULLETIN
·
2012
·
IF 2.105
Hongwei Wei,Hechun Jiang,Zhen Zheng,Quanqin Zhao,Qingyin Wu,Jinhua Zhan
A series of one-dimensional Cd x Zn (1− x ) S semiconductor alloys were prepared via a hydrothermal method with the assistance of ethylenediamine at 180 °C for 12 h. The products were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, nitrogen adsorption/desorption and Fourier transform infrared techniques. With the value of x increased, the band gap of Cd x Zn (1− x ) S semiconductor alloys gradually decreased indicating that catalysts were exchanged to visible-light response. Photocatalytic reduction results showed that Cd 0.73 Zn 0.27 S exhibited the highest photocatalytic activity toward photo production of aniline via nitrobenzene reduction under visible irradiation respectively. The reaction mechanism was also discussed.
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ANDROLOGIA
·
2014
·Vol. 47
·期 9
·995-1003
·
IF 1.172
J. Li,Y. Hu,Q. Zhang,B. Ma,Z. Wu,Y. Wang,J. Sun,J. Zhu,H. Ying,P. Ouyang
Summary This study investigated the treatment effects of a new compound, strontium fructose 1, 6-diphosphate (FDP-Sr), in cyclophosphamide (CP)-induced oligozoospermia. FDP-Sr, with extra high-energy supply, could reverse male hypogonadism in the testis. Male Wistar rats were randomly divided into three groups: control group (vehicle treated), CP group and CP + FDP-Sr group. Both CP group and CP + FDP-Sr groups were orally administered CP (20 mg kg −1 ) consecutively for the first 7 days to establish CP-induced testicular toxic models. Subsequently, CP group was given orally distilled water per day, whereas CP + FDP-Sr group was received FDP-Sr (200 mg kg −1 ) for 49 days. Compared to the CP group, the FDP-Sr group showed significantly increased levels of serum testosterone, testis relative weights and epididymal sperm counts in rats. In addition, rats treated by FDP-Sr showed the recuperative activities of testicular marker enzymes and normalised levels of antioxidants in tissue. Testicular protection of FDP-Sr was further demonstrated by enhancing expression of P450scc, reducing ability of FAS/FASL and generating cytoprotection in the histopathological study. FDP-Sr appeared to possess an ability to attenuate CP-induced reproduction toxicity via the activation of antioxidants and steroidogenesis enzymes, and alleviate oligozoospermia via inhibition of testicular apoptosis by FAS/FASL pathway.
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CHEMICAL ENGINEERING JOURNAL
·
2013
·
IF 3.473
Yingying Luo,Ziyang Lu,Yinhua Jiang,Dandan Wang,Lili Yang,Pengwei Huo,Zulin Da,Xuliang Bai,Xulan Xie,Pengyi Yang
The magnetic and dual conductive imprinted photocatalysts (MCIPs) were synthesized through the suspension polymerization method. TiO 2 /Fe 3 O 4 /MWCNTs, 1-methylimidazole-2-thiol and pyrrole were used as supports, template molecule and functional monomer, respectively. The MCIPs were further characterized by X-ray diffraction (XRD), Fourier transform infrared spectra (FT-IR), scanning electron microscopy (SEM), transmission electron microscope (TEM), UV–visible diffuse reflectance spectra (UV–vis DRS), thermogravimetric analysis (TGA) and vibrating sample magnetometer (VSM). The result revealed that polypyrrole (PPy) was formed and well embedded in the surface imprinted layer of TiO 2 /Fe 3 O 4 /MWCNTs. Owing to PPy and MWCNTs, the MCIPs was equipped with dual conductivity which was particularly useful for photodegradation of 1-methylimidazole-2-thiol in aqueous solution under ultraviolet irradiation. Through a series investigation of factors, it was obvious that when the polymerization time was 24 h and the adding dose of pyrrole was 8 mmol, the resulting MCIPs obtained the highest photocatalytic ability. In addition, the photodegradation process obeyed the pseudo-first-order kinetic reaction and exhibited an excellent selective degradation ability of 1-methylimidazole-2-thiol. The degradation intermediate products and mechanism of 1-methylimidazole-2-thiol were further discussed.
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