Frontiers of Chemical Science and Engineering
·
2017
·Vol. 11
·期 4
·564-574
·
IF 1.712
Song Baodong,Li Yongqiang,Cao Gang,Sun Zhenhai,Han Xu
In the transformation of methanol to gasoline (MTG), the selectivity to gasoline and the aromatic content in the produced gasoline are important factors. The catalytic activities of steam-treated and non-steam-treated nano-scale H-ZSM-5 (NHZ5) catalysts impregnated with Ag(I), Zn(II) or P(V) have been investigated in a continuous flow fixed bed reactor. The NH 3 -TPD results showed that after impregnation, the Ag/NHZ5, Zn/NHZ5 and P/NHZ5 catalysts contained comparatively more strong, medium-strong and weak acid sites, respectively. Treatment with steam decreased the number of acid sites in all the catalysts, but the pore volumes in the catalysts were larger which improved carbon deposition resistance resulting in prolonged lifetimes. After 6 h of MTG reaction, the selectivity to gasoline for the steam-treated catalysts,
\(Ag_{H_2 O} /NHZ5\) , \(Zn_{H_2 O} /NHZ5\) and \(P_{H_2 O} /NHZ5\) were 70.5, 68.4 and 68.7 wt-%, respectively, whereas their respective aromatic contents in the produced gasoline were 61.9, 55.4 and 39.0 wt-%. Thus \(P_{H_2 O} /NHZ5\) is the most promising catalyst for MTG applications which can meet the China IV gasoline standard that the amount of aromatics in gasoline should be less than 48 wt-%.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 16
·24398-24411
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IF 0
Xie Yuxuan,Peng Xiao,Song Xin,Ning Ping,Sun Xin,Ma Yixing,Wang Chi,Li Kai
CH 3 SH is a potential hazard to both chemical production and human health, so controlling its emissions is an urgent priority. In this work, a series of transition metal-loaded H-ZSM-5 adsorbents (Si/Al = 25) (Cu, Fe, Co, Ni, Mn, and Zn) were synthesized through the wet impregnation method and tested for CH 3 SH physicochemical adsorption at 60 °C. It was shown that the Cu-modified H-ZSM-5 adsorbent was much more active for CH 3 SH removal due to its abundant strong acid sites than other transition metal-modified H-ZSM-5 adsorbents. The detailed physicochemical properties of various modified H-ZSM-5 adsorbents were characterized by SEM, XRD, N 2 physisorption, XPS, H 2 -TPR, and NH 3 -TPD. The effects of metal loading mass ratio, calcination temperature, and acid or alkali modification on the performance of the adsorbent were also investigated, and finally 20% Cu/ZSM-5 was found to have the best adsorption capacity after calcined at 350 °C. Additionally, the Cu/ZSM-5 adsorbent modified by sodium bicarbonate could expose more active components, which improved the adsorbent’s stability. However, the consumption and reduction of the active component Cu 2+ and the accumulation of sulfate during the adsorption process are the main reasons for the deactivation of the adsorbent. In addition, the simultaneous purging of N 2 + O 2 can effectively restore the adsorption capacity of the deactivated adsorbent and can be used as a potential strategy to regenerate the adsorbent. Graphical
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2025
·
IF 2.1
Yaqi Han,Fumin Xue,Wenguo Xing,Huanhuan Yin,Xiangchuan Wang,Shuai Yu
Solid–liquid equilibrium solubilities of 2-mercapto-5-methyl-1,3,4-thiadiazole (MMTD) in 12 kinds of monosolvents (i.e., methanol, ethanol, n-propanol, i-propanol, n-butanol, i-butanol, ethyl formate, methyl acetate, ethyl acetate, propyl acetate, butyl acetate, and amyl acetate) were determined by a gravimetric method with the temperature range from 283.15 to 323.15 K. In alcoholic solvents, the solubility order is ethanol > methanol > n-propanol > i-propanol > n-butanol > i-butanol. In ester solvents, the solubility of MMTD ranking is methyl acetate > ethyl acetate > propyl acetate > butyl acetate > amyl acetate > ethyl formate. The solubility of MMTD increased with increasing temperature. Four thermodynamic models (i.e., the modified Apelblat model, the λh model, the Wilson model, and the Jouyban model) were selected to correlate the solubility data. The RAD and RMSD values were less than 0.0254 and 0.000536, respectively. The Wilson model had the best-fitting effect. The KAT-LSER model and Hansen solubility parameters were used to explain the solvent effect in this work. The Hirshfeld surface, molecular electrostatic potential surface, and free energy of solvation were used to explain the interactions between molecules. Dissolution properties of MMTD were calculated by the Wilson model. The dissolution process of MMTD is endothermic, entropy driven, and spontaneous.
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Materials Today Chemistry
·
2025
·
IF 6.7
Shuo Zhang,Xue Yang,Longyongxue Ma,Junwei Ma,Hongtao Gao
The conversion of biomass into value-added chemicals is crucial for addressing resource shortages and mitigating environmental degradation. 5-Hydroxymethylfurfural (HMF), a promising biomass-derived platform compound, can be selectively oxidized to produce high-value 2,5-furandicarboxylic acid (FDCA). In this study, an amorphous bimetallic hydroxide, Ni 1 Co 2 -LDH, was synthesized for the effective electrocatalytic oxidation of HMF. Electrochemical experimental results indicate that Ni–Co dual sites synergistically participate in the oxidation of HMF. Co sites promote the transformation of the aldehyde (CH O) group to the carboxyl group, while Ni sites speed up the reaction rate of 2,5-furandicarboxylic acid (FDCA) generation. The construction of such a bimetallic site enables the Ni 1 Co 2 -LDH catalyst to exhibit a low onset potential (1.20 V vs. RHE) and high selectivity (100 %) in HMFOR. At 1.30 V (vs. RHE), the catalyst achieves a Faradaic efficiency of 90.5 % and an FDCA yield of up to 95.6 %. Furthermore, Ni 1 Co 2 -LDH exhibits exceptional structural and catalytic stability, maintaining an FDCA yield above 95.0 % after five consecutive electrochemical cycles. These findings highlight the potential of Ni 1 Co 2 -LDH, synthesized via a hydrothermal method, as an efficient anode catalyst for the sustainable production of high-value chemicals from biomass-derived compounds.
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NEW JOURNAL OF CHEMISTRY
·
2025
·Vol. 49
·期 24
·10338-10356
·
IF 2.5
Fan Bai,Yanjiao Gao,Yongbo Xiao,Jingyi Yang,Jiaxin Chen,Jing Xiao
In recent years, advanced oxidation based on periodate (PI) has become a research focus for disposal of recalcitrant organics from water due to its efficient oxidizing ability. This study systematically investigated the degradation of reactive black 5 (RB5) by the Cu(II)-activated sodium periodate (NaIO4, SPI) system. The optimal reaction conditions were determined via Box–Behnken response surface methodology as [Cu(II)] = 1.013 ± 0.021 g L−1, [SPI] = 45 ± 2 μM, and pH = 5.7 ± 0.3, achieving a RB5 removal rate of 91.98% (R2 = 0.9901, prediction error <1%). The free radical quenching experiment confirmed that the dominant ROS in the system were ˙OH, 1O2, and IO3˙, and their contribution was IO3˙ > 1O2 > ˙OH. The coexistence anion experiments showed that Cl− (0.1–5.0 mM) and SO42− (0.1–5.0 mM) had almost no effect on the RB5 degradation efficiency, with inhibition rates lower than 1.99% and 3.58%, respectively, while CO32− (1.0 mM) and HCO3− (1.0 mM) led to a decrease of 20.8% and 14.17% in the RB5 degradation rate. In the presence of HA, the degradation efficiency of RB5 was maintained at 89.88–92.66%. The system maintained a removal rate of 73.33–87.66% for RB5 in the simulated actual water bodies (tap water/river water/brewery wastewater). Energy-assisted experiments showed that the activation energy of the reaction was significantly reduced and the kobs values were increased by 10.3 times when the temperature was increased to 40 °C, and the reaction time could be shortened to 2 min (removal rate >98%) after ultraviolet (365 nm, 20 W) coupling. In summary, this study is expected to support the related PI-based advanced oxidation process in stubborn pollutant treatment.
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INTERNATIONAL IMMUNOPHARMACOLOGY
·
2025
·
IF 4.7
Rihong Luo,Yuhan Kang,He Ma,Zhenqiang Zhang,Christian Hölscher,Li Hao,Zijuan Zhang
To date, no therapeutic drugs available on the market can effectively reverse the progression of Alzheimer's disease (AD). Although Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) and Cholecystokinin (CCK) RAs have shown some promise in AD research, little is known about the neuroprotective effects of a novel dual CCK/GLP-1 RA in AD. This study sought to examine the effects of the novel dual CCK/GLP-1 RA on cognitive performance in an AD mouse model and to explore the associated mechanisms. Our findings indicate that dual CCK/GLP-1 RA improved cognitive deficits, reduced amyloid-beta (Aβ) accumulation, and alleviated mitochondrial damage in 5 × FAD mice by inducing mitophagy. In an in vitro model of AD cells induced by Aβ, CCK/GLP-1 RA could exert neuroprotective effects by regulating PINK1/Parkin-mediated mitophagy. These data reveal for the first time that the new CCK/GLP-1 RA modulates mitophagy via PINK1/Parkin pathway and enhances cognitive function in the 5 × FAD animal model. Moreover, the performance of the CCK/GLP-1 RA in certain indicators was superior to that of GLP-1 analogue liraglutide, suggesting that it may represent a more promising therapeutic option for AD.
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PubMed
高影响因子
BIOMEDICAL CHROMATOGRAPHY
·
2025
·Vol. 40
·期 1
·e70278
·
IF 1.7
Junni Fan,Yu Li,Ge Wang,Qian Li,Minfeng Fang
This study employed an affinity chromatography approach to investigate the potential molecular mechanism of the Albiziae Cortex and Polygoni Multiflori Caulis herbal pair, which is commonly used for treating insomnia. Briefly, the haloalkane dehalogenase and its substrate were fused separately onto the serotonin 1A receptor and amino microspheres. Receptors were bound onto chromatographic stationary phases specifically through biological orthogonal interactions. Subsequently, catechin, methyl-O-digalloyl-hexose, 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (THSG), and julibroside J 35 were identified as active components in the herbal pair extract targeting the receptor. A mice model of insomnia was used to validate the anti-insomnia effects. The herbal-pair extract, catechin, and THSG significantly reduced sleep latency and increased sleep duration. Furthermore, on-column analysis and molecular docking revealed the binding characteristic. Adsorption isotherm analysis indicated a homogeneous binding process, which was further supported by injection amount-dependent analysis. The latter also provided binding constants of (5.70 ± 0.61) × 10 5 M −1 for catechin and (4.05 ± 0.20) × 10 5 M −1 for THSG. Molecular docking revealed critical binding residues (Asp116, Val117, Thr121, Lys191, Thr196, and Ser199), primarily via van der Waals forces and hydrogen bonds. Collectively, immobilizing the serotonin 1A receptor enables the screening of biologically active compounds from complex systems effectively and shows a degree of general applicability.
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JOURNAL OF CHEMICAL THERMODYNAMICS
·
2026
·
IF 2.5
Wentao Zheng,Jialing Chen,Xinwen Zhang,Lu Xu,Qian Gu,Xianku Wu,Xuehua Zhang
The development of efficient, low-viscosity, and environmentally friendly solvents is essential for sustainable CO 2 capture. In this study, a series of ternary deep eutectic solvents (DEAz-DESs) were synthesized using 1,5-diazabicyclo[4.3.0]non-5-ene (DBN) as the hydrogen bond acceptor, and ethylene glycol (EG) along with various azoles as hydrogen bond donors. These DESs exhibited excellent physicochemical properties, including low viscosity (7.83–41.41 mPa·s at 40 °C) and high thermal stability ( T d = 112–133 °C). The low viscosities enabled rapid CO 2 mass transfer and absorption kinetics. Among them, the DBN/Pyrazole/EG (3:1:1) system demonstrated a high CO 2 uptake of 0.194 gCO 2 /gDES at 1 bar and 40 °C. Combined spectroscopic characterization and DFT calculations elucidated dual chemisorption mechanisms: carbamate formation through pyrazolate and carbonate formation mediated by DBN-activated EG, jointly accounting for the elevated CO 2 absorption capacity. Thermodynamic analysis yielded moderate absorption enthalpies (−38 to −63 kJ/mol), indicating favorable regeneration at mild temperatures. The DBN/Pyrazole/EG (3,1:1) DES retained over 90% of its absorption capacity after 10 cycles, demonstrating excellent reusability. Compared with other reported DESs, the DEAz-DESs presented in this work offer superior absorption performance and lower viscosities. These findings suggest that the ternary DBN/azole/EG systems are promising candidates for efficient and sustainable post-combustion CO 2 capture applications.
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Catalysts
·
2026
·Vol. 16
·期 1
·69
·
IF 4
Lin-Yu Jiao,Ze-Long Sun,Wen-Yu Luo,Fei Wen,Jun-Bo Ye,Kang-Lai Chen,Long Xu,Bin Tian,Shan-Shan Liu
In recent years, biomass utilization has attracted extensive attention. Herein, hexagonal/cubic ZnIn2S4(ZIS) heterojunction catalysts were synthesized via a solvothermal method for the selective oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-diformylfuran (DFF). The results demonstrated that the constructed heterojunctions effectively promoted carrier separation. The optimal catalyst achieved an HMF conversion rate of 88.8% and a DFF yield of 86.6% within 1 h in the open air. X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) characterizations confirmed the successful fabrication of the composite phase structure and revealed a porous spherical morphology. Equivalent circuit fitting of electrochemical impedance spectroscopy (EIS) data indicated that the hexagonal/cubic heterojunctions possessed the lowest charge transfer resistance (Rct = 5825 Ω), which effectively reduced interfacial charge transfer resistance and accelerated the transport of photoinduced carriers. Radical quenching experiments and electron paramagnetic resonance (EPR) spectroscopy identified superoxide radicals (·O2−) as the primary reactive species. Meanwhile, density functional theory (DFT) calculations elucidated the formation of the built-in electric field and the charge transfer mechanism. This work’s construction of Type-II ZIS heterojunctions effectively addressed the issue of rapid carrier recombination in pristine ZIS materials, providing a feasible strategy for biomass valorization.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2026
·
IF 19.7
Jie Li,Yuxiang Yang,Guangtong Xu,Xiangxu Du,Anbang Dai,Yangchuan Ke
Spatially orthogonal CeO x –Zn sites were integrated into aerogel-derived hierarchical HZSM-5. • CeO x shifted HCl release and chlorinated-intermediate conversion to lower temperatures. • Zn promoted BTX-selective aromatization of dechlorinated and oxygenated fragments. • Accessibility-weighted bifunctional catalysis enabled cleaner and higher-value PVC/PET upcycling. Catalytic upcycling of chlorine-containing mixed plastics remains limited by the intrinsic conflict between efficient dechlorination and high-selectivity aromatization. Here we report a spatially orthogonal CeO x –Zn/Aero-40 catalyst derived from a diatomite-aerogel-templated hierarchical HZSM-5 support, in which CeO x -rich outer mesopores and Zn-containing MFI channels are integrated into a gated tandem architecture. The hierarchized support decreased the mean particle size from 386 ± 42 nm for Conv-40–274 ± 31 nm for Aero-40 and retained a shortened crystallite length of 289 ± 24 nm after dual-site loading, while exposing 3.01 wt% surface Ce and 1.86 wt% surface Zn on CeO x –Zn/Aero-40. Under the optimized two-stage conditions, CeO x -Zn/Aero-40 affords a BTX yield of 64.0 wt% on the initial dry-polymer feed basis, a BTX selectivity of 90.0% within the quantified liquid aromatics, and a dechlorination efficiency of 98.9%. Product-family analysis showed that aromatics rose to 71% whereas organochlorines fell to 2%; chlorine balance further demonstrated that 88% of chlorine was released as gaseous HCl, with only 3% remaining as oil-phase organochlorine. Taken together, the time-resolved spectroscopic/thermal analyses, probe experiments and kinetic measurements are consistent with a functionally staged mechanism in which Ce-associated sites facilitate low-temperature HCl elimination and chlorine management, whereas Zn-associated acid environments favor downstream cyclization/dehydrogenation-aromatization toward BTX. The DFT calculations support the intrinsic feasibility of these site-specific elementary steps but do not, by themselves, establish dynamic inter-site kinetic coupling. Across ten independent parallel runs, the mean BTX yield was 63.9 wt% of the initial dry polymer feed (RSD 1.0%), while the mean dechlorination efficiency was 98.8% (RSD 0.2%), retained 96.3% Zn after five cycles, and maintained high dechlorination efficiency for model and real feeds. These results establish a hierarchical dual-site zeolite platform for chlorine-tolerant aromatics-oriented upcycling of PVC/PET mixed plastics. Download: Download high-res image (274KB) Download: Download full-size image
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Journal of Functional Foods
·
2026
·
IF 3.9
Li Dong,You Wu,Yangshu Zhou,Hongrong Wang,Lihuai Yu
Menthol is a widely consumed dietary monoterpene found in peppermint oil, yet its effects on intestinal health under inflammatory conditions remain poorly understood. This study investigated the protective effects of dietary menthol against lipopolysaccharide (LPS)-induced intestinal inflammation in a weaned piglet model, focusing on the enteroendocrine Piezo1/TPH1/5-HT signaling axis. Sixty 28-day-old Duroc × (Landrace × Large White) weaned piglets were randomly assigned to five groups: a non-challenged control (CON), an LPS-challenged group, and three LPS-challenged groups receiving menthol at 12.5, 25, or 50 mg/kg of diet in a 22-day trail (21-day feeding +6 h post-LPS). Supplementation with 25 mg/kg menthol of diet significantly increased average daily body weight gain (ADG) and average daily feed intake (ADFI) while reducing the incidence of diarrhea before LPS challenge ( P < 0.05). After LPS administration, menthol markedly attenuated intestinal injury, as evidenced by reduced serum lactate dehydrogenase (LDH) activity and lower levels of pro-inflammatory cytokines interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in both serum and intestinal tissues ( P < 0.05). Morphologically, menthol increased villus height and the villus height to crypt depth ratio (VH/CD), decreased crypt depth ( P < 0.05), and preserved microvilli density, tight junction integrity, and nuclear morphology of the small intestine. Notably, menthol partially restored the LPS-induced loss of enteroendocrine cells and normalized gut hormone profiles, specifically reducing serotonin (5-HT) and gastrin while increasing somatostatin. Mechanistically, menthol appeared to suppress the LPS-induced upregulation of the mechanosensor Piezo1, the 5-HT-synthesizing enzyme tryptophan hydroxylase 1 (TPH1), and the 5-HT3 receptor at both the gene and protein levels ( P < 0.05). These findings suggested that dietary menthol, particularly at 25 mg/kg of diet, alleviated intestinal inflammation, potentially by preserving enteroendocrine cell homeostasis and downregulating the Piezo1/TPH1/5-HT signaling pathway. This study provides new evidence for the potential application of menthol as a functional food ingredient to support gut health.
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ACS Catalysis
·
2026
·
IF 13.6
Peiyun Zhou,Shihao Feng,Xi Wang,Xiang Liu,Xingjian Xu,Xiubing Huang,Haohong Duan
Despite the practical advantages of conducting 5-hydroxymethylfurfural (HMF) electrooxidation to 2,5-furandicarboxylic acid (FDCA) in acidic media, such as facilitated product separation and improved reactant stability over alkaline environments, the lack of efficient electrocatalysts has hindered the development of efficient acidic processes. Herein, we reveal that HMF oxidation reaction (HMFOR) shares key oxygen-containing intermediates ([O], e.g., *OH and *OOH) with oxygen evolution reaction. By incorporating Ir into manganese oxide (MnOx), the kinetic constraints of acidic HMFOR were successfully broken. Specifically, in the designed Ir-MnOx, the presence of Ir sites not only accelerates the generation of [O] species to provide abundant oxidative active species but also modulates the electronic structure of Mn sites to activate their reactivity and enhance HMF adsorption. Synergistic cooperation between Ir and Mn sites endows Ir-MnOx with a record-high HMFOR current density (56.2 mA cm−2@1.40 VRHE), along with high FDCA selectivity (94%) and yield (92%) in an acidic electrolyte (pH 1.89). This work provides mechanistic insights and a design strategy for efficient HMFOR electrocatalysts in acidic environments.
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