JOURNAL OF NANOBIOTECHNOLOGY
·
2022
·Vol. 20
·期 1
·1-14
·
IF 9.429
Ruan Shuangrong,Yin Weimin,Chang Jiao,Yang Yan,Sun Jiuyuan,Ma Xiaoyi,Liu Ying,Zang Jie,Liu Yiqiong,Li Yongyong,Ren Tianbin,Dong Haiqing
Hypoxia and high accumulation of lactic acid in the tumor microenvironment provide fertile soil for tumor development, maintenance and metastasis. Herein, we developed a calcium peroxide (CaO2)-loaded nanostructure that can play a role of “one stone kill two birds”, i.e., acidic and hypoxic tumor microenvironment can be simultaneously regulated by CaO2 loaded nanostructure. Specifically, CaO2-loaded mesoporous polydopamine nanoparticles modified with sodium hyaluronate (denoted as CaO2@mPDA-SH) can gradually accumulate in a tumor site. CaO2 exposed in acidic microenvironment can succeed in consuming the lactic acid with oxygen generation simultaneously, which could remodel the acid and hypoxia tumor microenvironment. More importantly, the relief of hypoxia could further reduce lactate production from the source by down-regulating the hypoxia inducible factor-1α (HIF-1α), which further down-regulated the glycolysis associated enzymes including glycolysis-related glucose transporter 1 (GLUT1) and lactate dehydrogenase A (LDHA). As a result, CaO2@mPDA-SH alone without the employment of other therapeutics can dually regulate the tumor hypoxia and lactic acid metabolism, which efficiently represses tumor progression in promoting immune activation, antitumor metastasis, and anti-angiogenesis.
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高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2022
·Vol. 39
·期 6
·928-932
·
IF 2.726
Xu Zhonghang,Wu Yuanyu,Tao Ran,Jin Zhanbin,Fang Xuedong
I n recent years, many effective photocatalysts have been developed to solve the problem of environmental pollution and clean energy shortage. In this paper, non-noble metal cocatalyst Ni 3 N nanoparticles supported Zn 0.5 Cd 0.5 S(ZCS) nanorods(Ni 3 N/ZCS) composites were successfully synthesized by ultrasonic method. The hydrogen production efficiencies of the photocatalysts were tested under visible light, which was found that when the loading of Ni 3 N was 2% of the mass of ZCS, and the Ni 3 N/ZCS composite had the best hydrogen evolution performance, which could reach 70.3 mmol·h −1 ·g −1 . In addition, the quantum efficiency under 420 nm monochromatic light irradiation was 27.2%. Through different characterization analyses, such as X-ray diffraction(XRD), scanning electron microscopy(SEM), and UV-Vis diffuse reflectance spectra(DRS), a possible photocatalytic mechanism was proposed, providing some reference value for non-precious metals as cocatalysts.
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JOURNAL OF NANOPARTICLE RESEARCH
·
2023
·Vol. 25
·期 2
·1-14
·
IF 2.5
Ding Jianjun,Ye Li,Su Tong,Guo Naiyu,Yu Linbo,Miao Longxin,Cao Mian,Sun Chao
Surface-enhanced Raman scattering (SERS) features a unique fingerprint spectrum for fast and highly sensitive non-destructive detection without sample pretreatment. Aiming at the problem of few “hot spot” and uneven distribution of traditional SERS substrate, in this work, a surface-enhanced Raman substrate of silica/carbon nanotubes/silver nanoparticles (SiO 2 /CNTs/AgNPs) with high on all sides and low in the middle was synthesized by hydrothermal synthesis. The AgNPs were characterized by transmission electron microscopy (TEM), and the average diameter was 38 nm to 63 nm. The substrate exhibited high sensitivity, stability, and uniformity with a detection limit of 10 −12 M for rhodamine 6G (R6G). Furthermore, we conducted an in-depth research on the enhancement contribution of the substrate by finite-difference time-domain (FDTD); the simulation results were in good agreement with the experimental results. Finally, the substrate was used for the detection of phenol red in water; the results showed that the Raman intensity was exponentially related to the concentration of phenol red solution with the coefficient of determination R 2 = 0.99991, which provided a new method for detecting water pollutants. Graphical Abstract
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Scientific Reports
·
2023
·Vol. 13
·期 1
·1-14
·
IF 4.6
Wen Dingxin,Guo Qingqing,Zhao Wan,Yang Yong,Yang Chunlei,Yu Jun,Hu Yun
Since its discovery as a third unique gaseous signal molecule, hydrogen sulfide (H 2 S) has been extensively employed to resist stress and control pathogens. Nevertheless, whether H 2 S can prevent tobacco bacterial wilt is unknown yet. We evaluated the impacts of the H 2 S donor sodium hydrosulfide (NaHS) on the antibacterial activity, morphology, biofilm, and transcriptome of R. solanacearum to understand the effect and mechanism of NaHS on tobacco bacterial wilt. In vitro, NaHS significantly inhibited the growth of Ralstonia solanacearum and obviously altered its cell morphology. Additionally, NaHS significantly inhibited the biofilm formation and swarming motility of R. solanacearum , and reduced the population of R. solanacearum invading tobacco roots. In field experiments, the application of NaHS dramatically decreased the disease incidence and index of tobacco bacterial wilt, with a control efficiency of up to 89.49%. The application of NaHS also influenced the diversity and structure of the soil microbial community. Furthermore, NaHS markedly increased the relative abundances of beneficial microorganisms, which helps prevent tobacco bacterial wilt. These findings highlight NaHS's potential and efficacy as a powerful antibacterial agent for preventing tobacco bacterial wilt caused by R. solanacearum .
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高影响因子
Nano-Micro Letters
·
2023
·Vol. 15
·期 1
·1-17
·
IF 26.6
Chen Shengmei,Liang Xiongyi,Hu Sixia,Li Xinliang,Zhang Guobin,Wang Shuyun,Ma Longtao,Wu Chi-Man Lawrence,Zhi Chunyi,Zapien Juan Antonio
The strong interaction between Ti 3 C 2 S x and FeN 4 species induces the central metal Fe(II) in FeN 4 species with intermediate spin state transferred to high spin state, in which the latter is favorable to initiate the reduction of oxygen.
This strong interaction induces a remarkable Fe 3 d electron delocalization with d band center upshift, boosting oxygen-containing groups adsorption on FeN 4 species and oxygen reduction reaction kinetics.
The resulting FeN 4 –Ti 3 C 2 S x with FeN 4 moieties in high spin state exhibits high half-wave potential of 0.89 V vs. RHE and high limiting current density of 6.5 mA cm −2 , enabling wearable zinc–air battery showing a good discharge performance with a maximum power density of 133.6 mW cm −2 .
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2023
·Vol. 415
·期 8
·1477-1485
·
IF 4.3
Yuan Zhenfeng,Li Zhe,Zhao Xiaoxue,Ding Zhenyu,Xia Mingyuan,Dong Xuyang,Ni Pengjuan,Lu Yizhong
Hexavalent chromium is a highly toxic substance, which will pose a serious threat to human life and health and the entire ecosystem. Therefore, it is crucial to establish a simple and rapid detection method for hexavalent chromium. In this work, we fabricated bovine serum albumin–stabilized silver nanocluster (BSA-Ag 13 NC) which exhibited photoresponsive oxidase-like activity, catalyzing the oxidation of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to the blue oxidized state TMB (oxTMB) in a short time. Interestingly, 8-hydroxyquinoline (8-HQ) can significantly inhibit the color reaction of TMB oxidation while Cr(VI) can interact specifically with 8-HQ to restore this chromogenic reaction. Based on the above facts, a colorimetric sensing system for detecting Cr(VI) was developed. The sensing system shows a wide linear range, and good selectivity, with a low detection limit of 2.32 nM. Moreover, this sensing system could be successfully applied to the detection of Cr(VI) in lake water, tap water, and sewage with satisfactory results.
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高影响因子
RARE METALS
·
2023
·Vol. 42
·期 4
·1283-1293
·
IF 8.8
Niu Hao-Ting,Zhang Yi,Xiao Guang,He Xu-Hua,Yao Ya-Gang
Achieving thermal management composite material with isotropic thermal dissipation property by using an environmentally friendly and efficient method is one of the most challenging techniques as a traditional approach tending to form a horizontally arranged network within the polymer matrix or the preparation steps which are unduly cumbersome. What presented here is a close-stack thermally conductive three-dimensional (3D) hybrid network structure prepared by a simple and green strategy that intercalating the modified aluminum oxide (m-Al 2 O 3 ) spheres of different sizes into the modified two-dimensional (2D) boron nitride (m-h-BN) flakes. An effective 3D network is created by the multi-dimensional fillers through volume exclusion and synergistic effects. The m-h-BN flakes facilitate in-plane heat transfer, while the variously sized m-Al 2 O 3 spheres insert into the gaps between adjacent m-h-BN flakes, which is conducive to the heat transfer in the out-of-plane direction. Additionally, strong interactions between the m-Al 2 O 3 and m-h-BN promote the effective heat flux inside the 3D hybrid network structure. The 3D hybrid composite displays favorable quasi-isotropic heat dissipation property (through-plane thermal conductivity of 2.2 W·m −1 ·K −1 and in-plane thermal conductivity of 11.6 W·m −1 ·K −1 ) in comparison with the single-filler composites. Furthermore, the hybrid-filler composite has excellent mechanical properties and thermal stability. The efficient heat dissipation capacity of the hybrid composite is further confirmed by a finite element simulation, which indicates that the sphere–flake hybrid structure possesses a higher thermal conductivity and faster thermal response performance than the single-filler system. The composite material has great potential in meeting the needs of emerging and advancing power systems. Graphical abstract
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CELLULOSE
·
2022
·Vol. 30
·期 3
·1503-1515
·
IF 6.123
Liu Shiqi,Ji Hairui
In this study, a strategy of corncob valorization was proposed. Corncob was first pretreated with a recyclable acid hydrotrope ( p -TsOH, aqueous solution) to selectively remove lignin and hemicelluloses. After pretreatment, the collected liquid phase was diluted with deionized water to precipitate lignin. The hemicelluloses degradation products, mainly pentose, in the resulting acid liquor were converted into furfural with a yield of 53.65% without adding any catalyst. The collected lignin was depolymerized to phenolic monomers with a yield of 68.00% via a hydrodeoxygenation process. The pretreated cellulose-rich solid was subjected to 10 s ultrasonic treatment to form pulp and subsequently used for papermaking by blending it with commercial softwood pulp. With a corncob pulp addition of 20%, the tensile index and ring crush index of hand sheets increased by 10.62% and 5.05%, respectively, compared with those containing 100% softwood pulp. Therefore, this study provided a strategy for corncob valorization toward multipurpose fractionation: furfural, phenolic monomers, and pulp, reaching a comprehensive utilization of corncob. Graphical abstract
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Journal of Analysis and Testing
·
2022
·Vol. 7
·期 1
·16-24
·
IF 0
Ye Qiuyu,Dai Tao,Shen Jin,Xu Qin,Hu Xiaoya,Shu Yun
A new ratiometric fluorescent sensor based on the bifunctional carbon quantum dots (CQDs)@metal–organic framework (MOF) nanocomposite possessing peroxidase-mimicking catalytic and luminescent characteristics was developed for hydrogen peroxide (H 2 O 2 ) and cholesterol detection. The incorporation of fluorescent CQDs into the cavities of MIL-101(Fe) MOF with peroxidase-like activities endows the nanocomposite with bifunctional properties. The CQDs@MOF can oxidize o -phenylene-diamine to 2,3-diaminophenolazine by H 2 O 2 with yellow fluorescence (556 nm). Meantime, the intrinsic fluorescence signal (455 nm) of CQDs@MOF is inhibited due to the inner filter effect. Therefore, the ratio of the fluorescent intensity is employed as the signal output to construct the H 2 O 2 ratiometric biosensor. In addition, the cholesterol can be determined by the ratiometric sensor with high sensitivity. In addition, the total cholesterol in human serum is determined with high accuracy using our ratiometric biosensor. This ratiometric fluorescent platform based on the bifunctional CQDs@MOF provides new insights in the field of bio-sensing.
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2022
·Vol. 332
·期 1
·105-117
·
IF 1.754
Huang Xin,Shu Xiaoyan,Li Lingshuang,Chen Shuaipeng,Lu Xirui,Liao Bing,Xie Yi,Chen Shunzhang,Dong Faqin
Abstract Natural granite was considered for immobilizing nuclear waste Nd 2 O 3 (Nd 3+ simulated for An 3+ ). The structure and performance of pure granite were compared with Nd 2 O 3 doped granite sintered at 1500 °C. The introduced Nd 3+ distributed mainly in the glass network below the loading capacity (19 wt .%). Beyond that, tetrahedral SiO 4 units existed in a sheet form, while extra Nd 3+ precipitated as Nd 2 Si 2 O 7 . The doped Nd 2 O 3 improved the hardness (6.29–7.07 GPa) and density (2.19–2.71 g/cm 3 ) of matrix. Moreover, the solidified form presented NR Nd below 1.7 × 10 –6 g m −2 d −1 after 28 days. This work disclosed a potential host matrix for nuclear waste. Graphics abstract
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MICROCHIMICA ACTA
·
2022
·Vol. 190
·期 1
·1-10
·
IF 6.408
Wang Zhongrui,Ji Xinxin,Zhao Jingying,Ji Jie,Li Guangyao,Yang Guang,Xia Hongyan,Hou Juan
Fluorescein-functionalized fluorescent polymer dots (F-PDs) were prepared by a facile one-pot method by magnetic stirring under mild conditions based on carboxymethylcellulose (CMC) and fluorescein as the precursors. The obtained F-PDs exhibited a nanoscale size of 3.2 ± 1.1 nm, excellent water solubility, and bright yellow fluorescence emission with a fluorescence quantum yield of 12.0%. The fluorescent probe displays rapid and sensitive chiral discrimination for lysine focused on different complexation abilities between lysine enantiomers and Cu 2+ . The concentration of L-lysine in the range 4 to 14 mM ( R 2 = 0.997) was measured by the fluorescence intensity ratio ( I 513 / I 429 ); the exitation wavelength was set to λ ex = 365 nm. The detection limit was 0.28 mM (3 σ /slope). Importantly, this sensor accurately predicted the enantiomeric excess (ee) of lysine enantiomers at the designed concentration (lysine: 20 mM; Cu 2+ : 10 mM) ranges. The proposed sensor was successfully applied to determine L-lys (recovery: 95.8–101%; RSD: 0.465–3.34%) and ee values (recovery: 98.5–102%; RSD: 2.61–3.21%) in human urine samples using the standard addition method. Graphical abstract
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Journal of Superconductivity and Novel Magnetism
·
2023
·Vol. 36
·期 2
·711-719
·
IF 1.8
Huang Danqiang,Wen Xinchao,Dai Jianfeng,Wang Qing,Liu Hui,Li Zengpeng
In this study, SrFe 12 O 19 @MFe 2 O 4 (M = Co, Ni, Zn) core–shell nanofibers were fabricated by coaxial electrostatic spinning. The composites obtained at an annealing temperature of 900 °C are composed of SrFe 12 O 19 in pure phase and MFe 2 O 4 (M = Co, Ni, Zn) in different spinels. X-ray diffraction (XRD), field emission scanning electron microscope (FE-SEM), and transmission electron microscope (TEM) were used to describe the structure and morphology of nanofibers. Magnetic Property Measurement Systems (MPMS) are used to characterize the magnetic properties of nanofibers. Sr@Ni and Sr@Zn fibers all exhibit a unique core–shell structure, while Sr@Co fibers are connected by a lamellar structure. The single-phase hysteresis lines for each composite indicate the presence of exchange coupling effects between the hard/soft magnetic composite phases. The magnetic properties of the composites change as the soft magnetic material in the shell layer changes. Sr@Co has the highest M s (69.43 emu/g) and M r (33.82 emu/g), whereas Sr@Zn has the highest H c (2927 Oe). The switching plant curves indicate that the best exchange coupling of the three groups of samples is for Sr@Co. The magnetic properties of the composites are explained in terms of the nanofiber diameter, the exchange coupling between the two phases, and the nature of the soft magnetic phase itself. It is shown that the exchange coupling of composites is closely related to the type of composite.
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