ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2024
·
IF 3.8
Lv Jie,He Chengcai,Cao Jingcheng,Shuai Qiuyan,Liu Xifang,Li Meng,Lin Yulong
The abnormal expression of acetylcholinesterase (AChE) is linked to the development of various diseases. Accurate determination of AChE activity as well as screening AChE inhibitors (AChEIs) holds paramount importance for early diagnosis and treatment of AChE-related diseases. Herein, a fluorescent and colorimetric dual-channel probe based on gold nanoclusters (AuNCs) and manganese dioxide nanosheets (MnO 2 NSs) was developed. The fluorescence of AuNCs was suppressed in the presence of MnO 2 NSs, providing a platform for fluorescence-based detection. For colorimetric, the nanocomposites exhibited oxidase-like activity, rapidly catalyzing 3,3′,5,5′-tetramethylbenzidine (TMB) to generate a blue color. Thiocholine (TCh), produced through the enzymatic reaction of acetylthiocholine (ATCh) in the presence of AChE, can reduce the MnO 2 NSs, thus recovering the suppressed fluorescence of AuNCs and decreasing oxidase-like activity. Based on this principle, a dual-mode assay for AChE detection was achieved. Compared to the commonly used single-signal detection, multi-mode detection can offer reliable and accurate results, due to its inherent self-validation and self-regulation capabilities. Under optimum conditions, the limit of detection (LOD) for AChE activity was 0.067 mU mL –1 (fluorescent mode) and 0.042 mU mL –1 (colorimetric mode). Moreover, the probe realized AChE detection in biological samples and AChEIs screening. This work showed the great prospects for early diagnosis of AChE-related diseases. Graphical
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高影响因子
Tungsten
·
2025
·
IF 11.2
Zhao Jian-Ying,Mu Pan-Pan,Liu Hao,Chachina Svetlana B.,Zhang Xiao-Guang,Zhang Shao-Gang,Pan Dean
Waste fluidized catalytic cracking (FCC) catalysts contain strategic metals with high recycling value, and effective treatment of these waste catalysts is crucial for resource recovery and environmental protection. In this study, a leaching process of “oxidation treatment–alkali roasting–wet mill leaching” was proposed for the extraction of tungsten (W) and molybdenum (Mo) valuable metals from spent FCC catalysts, and a technological pathway suitable for industrial production was explored through a detailed investigation of the conversion mechanism and process optimization. After the pretreatment by oxidation and roasting at 600 ℃ for 4 h, the optimal conditions for alkali roasting were found to be 950 ℃ with the addition of three times the theoretical amount of alkali (Na 2 CO 3 ), which ensured full conversion and avoided the generation of impurities. Through one-factor exploration and response surface optimization, the average leaching rate for W and Mo reached 87.23% and 99.50%, respectively, under the wet mill leaching conditions of a 200-mesh particle size, liquid–solid ratio of 2.79, a wet milling time of 1.18 h, a pellet ratio of 6.44:1, and a roasting time of 114.61 min. It was observed that both heating leaching and wet mill leaching could achieve full extraction with a relatively small liquid–solid ratio, thereby minimizing the production and discharge of waste liquid. The formation of nickel tungstate (NiWO 4 ) was identified as the main factor limiting the leaching of W, and it was found that increasing the oxygen content during the roasting process could improve the leaching efficiency. This study provides practical guidance and a scientific basis for the environmentally friendly and resource-efficient utilization of spent FCC catalysts.
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BULLETIN OF MATERIALS SCIENCE
·
2025
·Vol. 48
·期 1
·1-13
·
IF 2.1
Lu Ning,Wang Yuyu,Song Gongji,Zhang Zifan,Li Pengfei,Wang Jiannan,Xu Jianmei
Conductive scaffolds are gaining increasing attention in peripheral nerve repair for their good biocompatibility and electrical properties similar to those of normal nerves. In this study, silk fibroin (SF) nanofibre mats coated with polypyrrole (PPy) were prepared through electrospinning and chemical polymerization. Scanning electron microscopy (SEM) showed even and firm coating of PPy around the nanofibres, and fourier transform infrared spectroscopy (FTIR) analyses of the conductive mats confirmed the presence of hydrogen bonds or electrostatic interactions between PPy and SF. The conductivity of the composite mats could be regulated by varying the pyrrole monomer concentration from 10–20 mM, resulting in corresponding changes in conductivity from 9.4 ± 3.4 × 10 –5 to 4.6 ± 1.0 × 10 –3 S cm –1 . The mechanical strength, hydrophilicity and biodegradability of the mats exhibited similar changing trends. Biodegradability tests showed weight losses of 51.2, 13.6, 11.2 and 15.1% for composite mats with varying PPy coating rates on the 28th day, revealing that the biodegradability can be regulated and optimised by varying the pyrrole concentration. Schwann cell culture confirmed that the SF/PPy mats improved cell proliferation and adhesion compared to pure SF mats. The results demonstrate that the SF/PPy mats, with nanoscale surface, excellent biocompatibility, conductivity and controllable biodegradability, represent promising materials with potential for use in peripheral nerve regeneration. Graphical
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Light-Science & Applications
·
2024
·Vol. 13
·期 1
·1-16
·
IF 20.6
Zhang Yongkang,Zheng Jie,Jin Fangzhou,Xiao Jie,Lan Ni,Xu Zhiyuan,Yue Xu,Li Zesen,Li Chengzhi,Cao Donglin,Wang Yifei,Zhong Wenbin,Ran Yang,Guan Bai-Ou
Chemotherapy is one of the conventional treatments for cancer in clinical practice. However, poor delivery efficiency, systemic toxicity, and the lack of pharmacokinetic monitoring during treatment are the critical limitations of current chemotherapy. Herein, we reported a brand-new antitumor drug delivery strategy that harnesses an optical fiber endoscopically therapeutic probe. The fiber probe carries photosensitizers in the fiber core and antitumor agents on the fiber surface mediated by a temperature-responsive hydrogel film, giving rise to an activable photothermal-chemotherapy that orchestrates the localized hyperthermia and thermal-stimuli drug release to the tumor lesion. Furthermore, the dynamical drug release and in-situ temperature can be real-time supervised through the built-in fiber sensors, including the reflective Mach–Zehnder interferometer and fiber Bragg grating, to visualize the therapy process and thus improve the safety of treatment. Compared with conventional methods, the fiber-optic drug delivery can adequately take advantage of the chemotherapeutics through collaboratively recruiting the photoheating-mediated enhanced permeability and the hydrogel particle-assisted high drug retention, shedding new light on a “central-to-peripheral” drug pervasion and retention mechanism to destroy tumors completely. The fiber-optic chemotherapy strategy incorporates precise drug delivery, accurate controllability of drug release, high drug permeability and retention in tumor, low off-target rate, and real-time drug release and temperature feedback, performing a straightforward and precise photothermal-chemotherapy pathway. More than that, the proposed strategy holds tremendous promise to provide a revolutionized on-demand drug delivery platform for the highly efficient evaluation and screening of antitumor pharmaceuticals.
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高影响因子
CELLULOSE
·
2024
·Vol. 31
·期 14
·8625-8645
·
IF 4.9
Li Na,Xiu Huijuan,Wu Haiwei,Shen Mengxia,Huang Shaoyan,Fan Sha,Wang Simin,Wu Minzhe,Li Jinbao
The lithium-sulfur battery (LSB) is a highly promising energy storage system with merits of exceptional theoretical specific capacity and energy density. However, challenges including insufficient sulfur conductivity, volume expansion, and the polysulfide shuttle effect result in rapid capacity decay and limited cycle life of the LSB, which significantly hinders its development. Inspired by the structure and forming process of paper, a fiber double network skeleton was constructed using flexible pulp fiber (PF) and highly conductive carbon fiber (CF). Following the principles of wet end chemistry in papermaking, MXene nanosheets with high adsorption and catalytic capacity for polysulfides were self-assembled on the surfaces of PF and CF to fabricate composite paper-based materials. The interwoven mesh of PF exhibited strong binding force and stable structure, providing support and protection for the CF interwoven mesh, resulting in a composite material with abundant porosity and excellent structural stability. Moreover, the CF interweaving network combined with an overlaid MXene interweaving network established an effective three-dimensional conductive pathway. When utilized as a self-supporting cathode in LSB, this composite paper-based material demonstrated outstanding cyclic stability. Under conditions of sulfur load at 2.3 mg·cm −2 and discharge at 0.2 C, the specific discharge capacity remained at 952 mAh·g −1 after 200 cycles with a capacity retention rate reaching 95.4%. The CF/PF@Mxene (CPCMX) also exhibited excellent tensile strength measured at 7.19 MPa while maintaining exceptional flexibility and electrolyte wettability. This research presents a highly promising solution for advancing the development of LSB with superior cycle stability.
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CELLULOSE
·
2024
·Vol. 31
·期 7
·4627-4644
·
IF 4.9
Yuan Hua-Bin,Zhao Manman,Zhu Xiaowei,Sha Desheng,Chen Guoqiang,Xing Tieling
Numerous techniques for achieving superhydrophobic modification of cotton fabrics are documented in existing literature. However, pursuing multifunctionality, especially concerning textile performance, remains a topic of significant research interest. This study introduced a straightforward yet highly effective method for producing modified cotton fabric (SFC) exhibiting a vibrant orange-yellow coloration, along with exceptional self-cleaning, stain-resistant, UV-blocking, anti-icing, and photothermal de-icing properties, through the utilization of ferric chloride hexahydrate (FeCl 3 ·6H 2 O) and polydimethylsiloxane (PDMS). The surface of the SFC was evenly coated with small nanoparticles, identified by X-ray diffractometer (XRD) as β-FeOOH. The SFC displayed a water contact angle of 165.9° and a sliding angle of 2°, demonstrating outstanding superhydrophobicity. In addition, the SFC achieved a UPF value of 80, indicating exceptional UV-blocking capabilities. Additionally, the SFC exhibited remarkable stability when subjected to harsh conditions, including exposure to strong acid (pH = 1) and alkali (pH = 13), various chemical reagents, 600 min of water washing, and 30 cycles of abrasion testing. The approach proposed in this study offers the advantages of cost-effectiveness, environmental friendliness, and fluorine-free characteristics, and is applicable across a range of fabrics, and has certain practical utility. Graphical abstract
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International Journal of Minerals Metallurgy and Materials
·
2024
·
IF 5.6
Qiu Yuhua,Huang Yingping,Wang Yanlan,Liu Xiang,Huang Di
Advanced processes for peroxymonosulfate (PMS)-based oxidation are efficient in eliminating toxic and refractory organic pollutants
from sewage. The activation of electron-withdrawing HSO
− 5
releases reactive species, including sulfate radical (·SO
− 4
), hydroxyl radical (·OH), superoxide radical (·O
− 2
), and singlet oxygen ( 1 O 2 ), which can induce the degradation of organic contaminants. In this work, we synthesized a variety of M-OMS-2 nanorods (M = Co, Ni, Cu, Fe) by doping Co 2+ , Ni 2+ , Cu 2+ , or Fe 3+ into manganese oxide octahedral molecular sieve (OMS-2) to efficiently remove sulfamethoxazole (SMX) via PMS activation. The catalytic performance of M-OMS-2 in SMX elimination via PMS activation was assessed. The nanorods obtained in decreasing order of SMX removal rate were Cu-OMS-2 (96.40%), Co-OMS-2 (88.00%), Ni-OMS-2 (87.20%), Fe-OMS-2 (35.00%), and OMS-2 (33.50%). Then, the kinetics and structure–activity relationship of the M-OMS-2 nanorods during the elimination of SMX were investigated. The feasible mechanism underlying SMX degradation by the Cu-OMS-2/PMS system was further investigated with a quenching experiment, high-resolution mass spectroscopy, and electron paramagnetic resonance. Results showed that SMX degradation efficiency was enhanced in seawater and tap water, demonstrating the potential application of Cu-OMS-2/PMS system in sewage treatment.
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高影响因子
Scientific Reports
·
2025
·Vol. 15
·期 1
·1-31
·
IF 3.9
Tian Kun,Li Chunping,Liu Huiming,Wang Lianchun
To enhance the adsorption capacity of biochar (BC), herein a novel multifunction modified biochar (SDMBC) was prepared by directly crosslinking of the nanomicelle of sodium dodecyl sulfate/sapindus-saponin (SDS/SAP) composite system onto the BC through a simple, environmental friendly approach. Result showed that the adsorption performance of SDMBC has been greatly improved, compared with BC or using alone SDS and SAP, adsorption ability increased by 48.83%, 29.50%, 36.44%, respectively, the best modified effect was appeared when the concentration of SAP to SDS was 0.8 and 0.8 CMC. SDMBC exhibited high adsorption abilities of 130.23, 108.43, 277.09 125.27, 112.78 mg/g for heavy metal ions lead Pb(II), Cadmium Cd(II) and organic pollutants with different chemical properties bisphenol A(BPA), Methylene blue (MB), P-nitrophenol (PNP), respectively, higher than most previously reported adsorbents, importantly, SDMBC can still efficient removal capabilities even in the binary competition. Subsequently, the SDMBC and BC was characterized by Fourier Transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), Zeta potential (Zeta), it found SDMBC has a more layered structure, richer functional groups and more amorphous structure compared with BC, which are closely related with improving its adsorption capacity. The adsorption behavior of SDMBC for MB show that process was found to be spontaneous, propitious, endothermic, the adsorption isotherms fitted Freundlich models well, pseudo-second-order best describes kinetics adsorption, suggesting that the process is multi-layer chemical adsorption. The little affected by ionic strength and coexisting substances, could remained removal rate over a wide pH range, SDMBC still keep high removal rates even after 5 reuses. Based on FT-IR analysis, plausible adsorption mechanism proposed, including hydrogen bond, electrostatic attraction and π-π bonding. Cost analysis manifests that the SDMBC are high efficiency and cheap eco-adsorbents compared with commercial activated carbon, and the SDMBC dosage required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted. Seven machine learning (ML) models were used to predict the MB (60 mg/L) adsorption of the SDMBC, using Shapley Additive Explanations (SHAP) for model interpretation. Finding Extreme Gradient Boosting (XGBoost) exhibited best performance, the order of feature importance as time> Ratio> pH> concentration> temperature. Thus, SDMBC as a new cheap and eco-adsorbents, can be used to effectively remove various types of pollutants, has a great application potential in sewage treatment, while the accurate ML prediction model presented a valuable advice for designing efficient adsorbents and optimization operating conditions in the future.
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高影响因子
Communications Materials
·
2024
·Vol. 5
·期 1
·1-8
·
IF 7.5
Ai Yuanfang,Zheng Na,Liu Wenbo,Yang Ping,Wu Xi,Tian Yichen,Wang Chuyi,Liu Heyang,Huang Chongping,Liang Zhongli,Zhu Feng,Tang Longcheng,Ye Nanbiao,Li Jianjun,Cao Kun
Frequent forest fires, driven by hotter and drier climates, threaten biodiversity and human health, causing significant economic losses, air pollution, soil erosion, and degeneration. Current active and passive fire protection methods often suffer from environmental pollution, poor flexibility, and limited availability in remote areas. However, fast-acting surface flame retardants for passive forest fire protection, particularly for foliage, are rare. Herein, we report an easily obtainable gelatin-based fire spray, which resulted in 1.8 and 16.3-fold extension in ignition time, 34% and 39% reductions in total heat release, 78% and 92% reductions in fire growth index for dead and fresh leaves, respectively. After the fire warning is suppressed, for instance by rain, the sprayed substances can decompose and provide nitrogen and phosphorus as leaf and soil fertilizers without affecting soil microbial function, which increase plant net photosynthesis by 84% and effective nitrogen and phosphorus by 664% and 140%, respectively. Our green flame retardant and fertilizer material allows for simultaneous tree fire protection and growth.
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高影响因子
Nano Research
·
2024
·
IF 9.5
Zhao Yuan,Wang Qingshuang,Yin Dongming,Wang Xiaoli,Li Shouliang,Wang Chunli,Liang Long,Zhao Shaolei,Wang Limin,Cheng Yong
α-AlH 3 is regarded as one of the most promising hydrogen storage materials due to its high hydrogen storage capacity (10.1 wt.%, 148 kg·m −3 ). However, in practical applications, the associated hydrogen release temperature remains relatively high. To effectively address this issue, hollow structured Fe@C nanorods derived from Fe-MOF are introduced as highly efficient catalyst to optimize the dehydrogenation properties of α-AlH 3 . Comparatively, the initial hydrogen release temperature of α-AlH 3 + 3 wt.% Fe@C is reduced to 94.2 °C, which is significantly lower than that of pure α-AlH 3 (137.8 °C). At 100 and 120 °C, it exhibits hydrogen capacities of 5.38 wt.% and 7.47 wt.%, respectively, whereas pure α-AlH 3 only delivers hydrogen capacities of 0.24 wt.% and 5.94 wt.% under the same temperatures. The density functional theory (DFT) calculations further indicate that the existence of Fe@C catalyst can make the length of Al–H bond increase, which is more conducive to the release of hydrogen. The results show that the synergistic effect of Fe and porous carbon in Fe@C nanorods can improve the hydrogen desorption kinetics of α-AlH 3 , providing a good prospect for the application of α-AlH 3 in hydrogen storage fields.
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CHINESE JOURNAL OF POLYMER SCIENCE
·
2024
·
IF 4.1
Wang Meng-Yun,Zhang Yue,Wang Dan,Yao Ming,Wang Yi-Xuan,Zhou Xing-Ping,Peng Hai-Yan,Xie Xiao-Lin
Holographic optical elements (HOEs) based on polymer composites have become a research hot spot in recent years for augmented reality (AR) due to the significant improvement of optical performance, dynamic range, ease of processing and high yield rate. Nevertheless, it remains a formidable challenge to obtain a large field of view (FOV) and brightness due to the limited refractive index modulation. Herein, we report an effective method to tackle the challenge by doping an epoxy liquid crystal termed E6M, which enables a large refractive index modulation of 0.050 @ 633 nm and low haze of 5.0% at a doping concentration of 5 wt%. This achievement may be ascribed to the improved molecular ordering of liquid crystals within the holographic polymer composites. The high refractive index modulation can endow transmission-type holographic polymer composites with a high diffraction efficiency of 96.2% at a small thickness of 5 µm, which would promise the design of thin and lightweight AR devices.
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BIOPROCESS AND BIOSYSTEMS ENGINEERING
·
2024
·
IF 3.5
Wang Lingqin,Jia Mengya,Gao Dandan,Li Haixing
The probiotic fermentation of the bioactive substance gamma-aminobutyric acid (GABA) is an attractive research topic. There is still room for further improvement in reported GABA fermentation methods based on a single substrate ( l -glutamic acid or l -monosodium glutamate). Here, we devised a pH auto-buffering strategy to facilitate the fermentation of GABA by Levilactobacillus brevis CD0817. This strategy features a mixture of neutral monosodium l -glutamate plus acidic l -glutamic acid as the substrate. This mixture provides a mild initial pH; moreover, the newly dissolved l -glutamic acid automatically offsets the pH increase caused by substrate decarboxylation, maintaining the acidity essential for GABA fermentation. In this study, a flask trial was first performed to optimize the GABA fermentation parameters of Levilactobacillus brevis CD0817. The optimized parameters were further validated in a 10 L fermenter. The flask trial results revealed that the appropriate fermentation medium was composed of powdery l -glutamic acid (750 g/L), monosodium l -glutamate (34 g/L [0.2 mol/L]), glucose (5 g/L), yeast extract (35 g/L), MnSO 4 ·H 2 O (50 mg/L [0.3 mmol/L]), and Tween 80 (1.0 g/L). The appropriate fermentation temperature was 30 °C. The fermenter trial results revealed that GABA was slowly synthesized from 0–4 h, rapidly synthesized until 32 h, and finally reached 353.1 ± 8.3 g/L at 48 h, with the pH increasing from the initial value of 4.56 to the ultimate value of 6.10. The proposed pH auto-buffering strategy may be popular for other GABA fermentations.
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高影响因子
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