JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
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2017
·Vol. 129
·期 3
·1875-1885
·
IF 1.953
Cheng Jian,Zheng Yu,Li Zhenming,Liu Zuliang,Li Lixia,Zhao Fengqi,Xu Siyu
Abstract The purpose of this work was to study the catalytic reaction and its mechanism of ammonium perchlorate (AP) with cobalt complex of 2,6-diamino-3,5-dinitropyrazine-1-oxide (Co-LLM-105) during thermal decomposition process. At first, the catalytic performance of Co-LLM-105 on the thermal decomposition of AP was investigated by TG–DSC, TG-FTIR, non-isothermal kinetic and α – T kinetic curves analyses. Secondly, the thermal decomposition mechanism of Co-LLM-105 in the absence and presence of AP was proposed based on TG, DTG, DSC and thermolysis/RSFTIR analyses. The results showed that Co-LLM-105 exhibited excellent catalytic activity on the thermal decomposition of AP. Meanwhile, AP also exhibited some catalytic effects on the thermal decomposition of Co-LLM-105. Both of the components had catalytic effects on each other during the process. The formation of active CoCO 3 , Co 3 O 4 , CoO and Co(NH 3 ) 6 (ClO 4 ) 2 in situ in the system accounted for the higher catalytic activity of Co-LLM-105 for the thermal decomposition of AP was deduced. Graphical Abstract Co-LLM-105 exhibited excellent catalytic activity on the thermal decomposition of AP. Meanwhile, AP also exhibited some catalytic effects on the thermal decomposition of Co-LLM-105. Both of the components had catalytic effects on each other during the process.
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LANGMUIR
·
2016
·
IF 3.993
Ping Zhang,Ling Li,Yun Zhao,Zeyun Tian,Yumei Qin,Jun Lu
The fluorescent dye 8-anilino-1-naphthalenesulfonate (ANS) is a widely used fluorescent probe molecule for biochemistry analysis. This paper reported the fabrication of ANS/layered double hydroxide nanosheets (ANS/LDH)n ultrathin films (UTFs) via the layer-by-layer small anion assembly technique based on electrostatic interaction and two possible weak interactions: hydrogen-bond and induced electrostatic interactions between ANS and positive-charged LDH nanosheets. The obtained UTFs show a long-range-ordered periodic layered stacking structure and weak fluorescence in dry air or water, but it split into three narrow strong peaks in a weak polarity environment induced by the two-dimensional (2D) confinement effect of the LDH laminate; the fluorescence intensity increases with decreasing the solvent polarity, concomitant with the blue shift of the emission peaks, which show good sensoring reversibility. Meanwhile, the UTFs exhibit selective fluorescence enhancement to the bovine serum albumin (BSA)-like protein biomolecules, and the rate of fluorescence enhancement with the protein concentration is significantly different with the different protein aggregate states. The (ANS/LDH)n UTF has the potential to be a novel type of biological flourescence sensor material.
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PROCESS BIOCHEMISTRY
·
2017
·
IF 2.497
Shu-Ping Zou,Ji-Wei Huang,Ya-Ping Xue,Yu-Guo Zheng
1-Cyanocyclohexaneacetic acid (1-CHAA) is an important intermediate in the preparation of gabapentin. Regioselective biotransformation of 1-cyanocyclohexaneacetonitile (1-CHAN) into 1-CHAA, mediated by the immobilization of recombinant microbial nitrilase, is a novel and promising strategy for its production. In this study, a recombinant E. coli expressing Acidovorax facilis nitrilase was flocculated with polyethylenemine, followed by cross-linking with glutaraldehyde to obtain cross-linked cell aggregates (CLCAs). Under the optimum preparation conditions, the activity recovery of CLCAs reached 68%. Characterization of the CLCAs showed that the optimum pH was not affected by cross-linking, but cross-linking resulted in slightly different optimum temperature. The half-life of CLCAs at 45 °C was 266.5 h, which is 11.6-times higher than that of the free cells. Preparative-scale biotransformation of 1-CHAN to 1-CHAA at high substrate loading (up to 1.0 M) was performed using CLCAs as the biocatalyst in a 2L stirred reactor, resulting in an conversion of 91%, with a productivity of 244.5 g L −1 d −1 . The CLCAs also exhibited a high operational stability and even after 30 cycles of reaction, it retained >80% of the initial conversion.
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POLYMER
·
2017
·
IF 3.684
Hongyao Ding,Xin Ning Zhang,Si Yu Zheng,Yihu Song,Zi Liang Wu,Qiang Zheng
As a promising structural material, various tough hydrogels have been developed in recent years by incorporating different kinds of noncovalent bonds as the energy-dissipating segments. Among these systems, it is challenging to use hydrogen bonds due to their instability in aqueous environment. Here we report a tough hydrogel of poly(1-vinylimidazole- co -acrylic acid) (P(VI- co -AAc)) reinforced by the robust hydrogen bonds between imidazole and carboxylic acid groups. The hydrogels with different composition possess excellent mechanical performances, with tensile breaking stress, breaking strain, Young's modulus , and tearing fracture energy being 0.3–1.8 MPa, 920–1400%, 0.1–0.7 MPa, and 0.7–5.6 kJ/m 2 , respectively, which are well maintained over a wide pH range (3 ≤ pH ≤ 10). The high stability of hydrogen bonds should be rooted in the strong proton donor-acceptor pair. However, when pH ≤ 2 or pH ≥ 11, the gels become highly swelled due to the dissociation of imidazole and carboxylic acid groups, respectively, accompanying with dramatic decrease in mechanical properties . The tough hydrogels also show temperature- and deformation rate-dependent mechanical properties , as well as shape memory and self-recovery abilities, due to the dynamic nature of noncovalent bonds. Such hydrogels with remarkable mechanical properties and dual pH-responsiveness should find applications in load-bearing soft actuators, flexible electronics, etc.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Shuyun Zhang,Baihua Peng,Yong Qi,Changpeng Xu,Yan Wang,Tinghui Xian,Jie Huang,Lin Liang,Zhen Lin,Hao Wu,Lihua Li
Impaired mitochondrial autophagy and ferroptosis in Human Immortalized Epidermal Cells (HaCats), caused by oxidative stress, are significant obstacles to diabetic wound healing. However, research on the mechanistic level of skin repair through the improvement of mitochondrial function and inhibition of iron-induced cell death by natural-based hydrogel materials is still lacking. In this study, we engineered pH and glucose-responsive Hst1@CBTC hydrogels leveraging dynamic borate bonding, exhibiting an impressive peptide release rate of up to 90 ± 4.2 %. In both in vitro and in vivo settings, the administered peptide demonstrated remarkable efficacy in counteracting cellular mitochondrial autophagy dysfunction and iron-induced cellular demise within oxidative stress environments. Consequently, the hydrogel facilitated expedited healing of recalcitrant diabetic wounds, showcasing a commendable wound closure rate of 94.7 ± 5.1 % within a span of 14 days. Of significant note, our findings elucidate the potential of Hst1@CBTC in ameliorating the cellular ferroptotic milieu by activating the Nrf/HO-1 pathway, thereby fostering mitochondrial autophagy restoration. This study proposes a theoretical solution to address mitochondrial dysfunction and ferroptosis in an oxidative stress environment. Additionally, it presents a safe hydrogel made from natural biosafety materials.
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Journal of Proteomics
·
2024
·
IF 2.8
Yan Cai,Weifu Ren,Siqian Li,Rijing Liao,Qi Bian
Idiopathic membranous nephropathy (IMN) is an antibody-mediated and kidney-specific autoimmune disease, with the antigen phospholipase A2 receptor 1 (PLA2R1) accounting for approximately 70% of IMN cases. Although a variety of new podocyte target antigens and their autoantibodies have been identified, they are still of limited diagnostic and therapeutic value due to lack of high specificity and sensitivity. N-glycans play vital roles in renal system and their pathobiological relevance has become increasingly recognized in many kidney diseases, but not fully explored in IMN. To find possible glyco-signatures for PLA2R1-related IMN diagnosis, we herein established a comprehensive workflow for total serum N-glycome analysis based on our recently developed mass spectrometry (MS)-based N-glycan purification method, named Ultrafast Glycoprotein Immobilization for Glycan extraction (UltraGIG). A total of 191 N-glycans were identified from IMN patients, representing the largest N-glycome dataset in IMN. Compared to healthy controls, up-regulation of sialylation and core-fucosylation as well as down-regulation of galactosylation were observed in PLA2R1-positive IMN patients, and up-regulation of hyper-galactosylation was specific for PLA2R1-negative IMN patients. A six-glycan marker panel consisting of H4N3S1, H4N3F1, H6N4S2, H6H5F1S2, H6N5 and H6N6F1S1, was proposed to aid in the accurate diagnosis of PLA2R1-related IMN, which provided new insights into IMN biomarker study . Significance PLA2R1-related IMN is a kidney-specific autoimmune disease with a high risk of developing end-stage renal disease (ESRD) and even kidney failure. Current biomarkers are still of limited diagnostic and therapeutic value due to lack of high specificity and sensitivity. An in-depth MS analysis of total serum N-glycome of PLA2R1-related IMN patients was conducted for the first time. We generated the largest dataset of serum N-glycome for IMN to date, and proposed a novel six-glycan marker panel that may help the accurate diagnosis of PLA2R1-related IMN.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jingjie Gao,Shaowei Bai,Fan Wang,Liangzhen Yang,Yufeng Hu,Yuhuan Yang,Bing Bai,Zuoming Zhang
Enzymatic glycosylation is an efficient and biocompatible approach to enhance natural product bioavailability. Cellobiose phosphorylase, a novel glycosyltransferase, utilizes 1-phospho-glucose (1-p-Glc) as a glycosyl donor for regioselective glycosylation of various natural substrates. However, the high cost of 1-p-Glc limits the economic feasibility of the process. Thus, a dual-enzyme cascade system involving cellulase Ac Cel9A and cellobiose phosphorylase Cb CBP using a co-immobilization strategy was developed to overcome this challenge. The system utilizes low-cost carboxymethyl cellulose (CMC) for continuous 1-p-Glc production, which was then used in the fluorodeoxy glucose (FDG) glycosylation to generate fluorodeoxy cellobiose (FDC), which potentially traces fungal infections. The compartmentalized co-immobilization of the two enzymes within the internal and external regions of a porous zeolitic imidazolate framework-8 (ZIF-8) carrier enhanced the overall stability of the dual-enzyme system. The immobilized enzymes retained approximately 63.3 % activity after seven reuse cycles and 74 % catalytic efficiency after 12 days of storage at room temperature. Therefore, the developed co-immobilized multi-enzyme system holds significant potential for industrial biocatalysis applications.
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Small
·
2024
·
IF 13
Guilin Wei,Linsen Zhou,Xianglin Wang,Ru Tang,Kelin Chen,Junhong Luo,Jiangfeng Song,Yan Shi,Ning Liu,Xingwen Feng
The construction, use, and maintenance of tritium-related equipment will inevitably produce tritium-containing radioactive waste gas, and the production of efficient catalysts for tritium removal remains a difficult problem. Herein, silicalite-1 zeolite with entrapped Pt nanoclusters is skillfully post-oxidized at an appropriate temperature, building highly active Pt─O sites on the nanoclusters to achieve efficient oxidation of hydrogen isotopes at low temperatures. The designed Pt─O sites can directly participate in the oxidation reaction of hydrogen isotopes. Compared to the case without Pt─O sites, the presence of these sites significantly reduces the reaction energy barrier to 0.55 eV, enabling the catalyst to achieve a hydrogen conversion rate of 99% at a low temperature of 40 °C. Specifically, the O atoms consumed by the Pt─O sites in the reaction are replaced by O 2 gas and this cycle repeats, which is consistent with the Mars-van Krevelen (M–K) theory. This ensures efficient catalytic oxidation of hydrogen isotopes, and provides an astonishingly high conversion rate of 99% in the nearly 34 days restart performance test. The results of this study provide insights into the strategic design of efficient catalysts for hydrogen isotope oxidation.
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高影响因子
LANGMUIR
·
2024
·
IF 3.7
Qiqi Huang,Fuxiao Zhu,Feiyan Xiao,Gongliang Zhang,Hongman Hou,Jingran Bi,Shuang Yan,Hongshun Hao
In recent years, piezo-photocatalysis has become a promising strategy for solving environmental pollution problems by adding additional mechanical energy to the photocatalysis process. This work reported the effective synthesis of a variety of HKUST-1/BiVO4 heterogeneous materials by combining monoclinic BiVO4 and porous HKUST-1 semiconductors. The piezo-photocatalytic properties of HKUST-1/BiVO4 were studied by the reduction of hexavalent chromium (Cr(VI)) under visible-light irradiation and ultrasonic waves. In the piezo-photocatalysis process, the best reduction rates among as-prepared HKUST-1/BiVO4 composites were up to 96.20% of 10 ppm Cr(VI) solution, which was approximately 1.80 times that under visible light and about 4.13 times that under ultrasound. Under the action of the piezoelectric potential, the availability of free radicals increased the reduction rate of Cr(VI) and reached a synergistic effect of 1.14-fold.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2025
·Vol. 23
·期 1
·1-20
·
IF 12.6
Tang Weiwei,Huang Xiaomin,Yi Yun-Di,Cao Fan,Deng Manli,Fan Jiawei,Jiang Zheng-Xuan,Tao Li-Ming,Wang Xianwen,Shi Lei
Globally, uveitis is a collection of intraocular inflammatory disorders that affect mainly the uvea, resulting in irreversible blindness and a heavy socioeconomic burden. Excessive autoimmune inflammation and oxidative stress are major drivers that contribute to the initiation and progression of uveitis. Nevertheless, current therapeutic methods for uveitis are limited and are accompanied by several serious adverse effects. Recently, nanotechnology-based antioxidant strategies have provided novel options for the treatment of ocular diseases. Although curcumin (CUR) has prominent antioxidant capacity and reactive oxygen species (ROS) scavenging ability, its low bioavailability and undetermined mechanisms limit its extensive application. This investigation demonstrated that esterified hyaluronic acid-curcumin nanoparticles (HA-CUR NPs) with superior aqueous dispersion exhibited exceptional antioxidant enzyme mimetic activity, incorporating superoxide dismutase (SOD), glutathione (GSH), catalase (CAT), and free radical scavenging ability. Further in vitro and in vivo experimental results validated the protective function of HA-CUR NPs against oxidative stress-induced damage and inflammatory responses, attenuated pathological progression, relieved microvascular damage, and regulated fundus blood flow in retinal vascular networks. This may be attributable to the specific ability of HA-CUR NPs to target the CD44 receptor and activate the Keap1/Nrf2/HO-1 signaling pathway, suggesting a potential mechanism. In summary, this study revealed that HA-CUR NPs, which are composed of a natural product and biomacromolecules with outstanding artificial antioxidant enzyme activities, may be novel agents for effectively and safely treating uveitis and other ROS-related diseases.
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JOURNAL OF POWER SOURCES
·
2024
·
IF 8.1
Yanhong Ding,Shiyu Wang,Chunyan Wei,Yuxin Chen,Jinlong Li,Yantao Wang,Honghong Fan,Guangyue Bai,Huanhuan Li
Polyoxometalates (POMs) are widely thought as promising choices for sodium-ion batteries (SIBs) because of their refined molecular structures and excellent reversible multielectron charge-discharge behaviors. Nevertheless, the POMs anion clusters could dissolve in the electrolyte when attacked by solvent molecules, thus reducing active sites and affecting the actual performance of these POMs-based electrodes. Herein, we report the development of a new type of electrode system that produces single-dispersed POMs molecular cluster/polydopamine/reduced graphene oxide composites ({PMo12}/PDA@rGO) through a self-assembly method. PDA acts as the role of “killing two birds with one stone”. It not only works as the linker to promote the formation of stable and uniform monodisperse {PMo12} clusters on the rGO surface, but also prevents the POMs from desorbing and dissolving upon deep cycling test. As a consequence, when used as the anode material for SIBs, the obtained {PMo12}/PDA@rGO exhibits an admirable long-term cycling performance, for instance, it holds a high Na-storage capacity of 277.5 mAh g −1 with an average Coulomb efficiency up to 99.89 % over 2000 cycles at 1 A g −1 . This work offers versatile possibilities for designing POMs-based composites and provides new insight into developing single dispersed POMs for advanced SIBs.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Zicheng Chen,Xuefeng Zhang,Kai Xu,Xiangyang He,Junkai Li,Lanhe Zhang,Guanhua Wang
As a cellulose-derived material, nanocellulose possesses unique properties that make it an ideal substrate for various functional composite materials . In this study, we developed a novel composite membrane material capable of adsorbing and photo-catalyzing formaldehyde by immobilizing HKUST-1 (copper open framework composed of 1,3,5-benzenetricarboxylic acid) onto NFC (Nano-fibrillated cellulose) membranes and subsequently loading modified carbon nitride . The synthesized CNx@HN composite membrane (consisting of NFC membrane with anchored HKUST-1 and modified g-C 3 Nx nanosheets) was thoroughly characterized, and its photocatalytic degradation performance towards low concentrations of formaldehyde (3.0 mg/m 3 ) was investigated. The results demonstrated that HKUST-1's porous nature exhibited a concentrated adsorption capacity for formaldehyde, while the modified CNx (Modified g-C 3 Nx nanosheets) displayed robust photocatalytic degradation of formaldehyde. The synergistic effect of HKUST-1 and modified CNx on the NFC membrane significantly enhanced the efficiency of formaldehyde degradation. Under xenon lamp irradiation, CNx@HN-5 achieved a total removal efficiency of 86.9 % for formaldehyde, with a photocatalytic degradation efficiency of 48.45 %, showcasing its exceptional ability in both adsorption and photocatalytic degradation of formaldehyde. Furthermore, after 10 cycles of recycling, the composite membrane exhibited excellent stability for the photocatalytic degradation process. Therefore, this study presents a green and facile strategy to fabricate nanocellulose-supported composite membranes with great potential for practical applications in formaldehyde degradation.
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危险品化学品经营许可证（带存储）