ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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2022
·Vol. 29
·期 25
·37266-37276
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IF 5.19
Zhang Li,Lan Shuang,Dou Quanhao,Hao Shiwei,Wang Yueping,Peng Yongzhen
The zero-valent iron-anaerobic ammonium oxidation (ZVI-anammox) system has received widespread attention due to its excellent nitrogen removal performance and user-friendly operation. However, its disadvantages include a short service life, high ZVI consumption, and poor system stability. The use of ultrasound as a physical method is increasing in various water treatment processes. In this study, a series of batch tests were conducted to obtain the best ultrasonic parameter and explore the comprehensive effects of ultrasound on a ZVI-anammox system. The highest specific anammox activity of the ZVI-anammox system was found to be 2.88 mg total nitrogen/g of volatile suspended solids/h after ultrasonic treatment (0.2 w/mL, 5 min), which was 37.85% higher than a control group. Additionally, the service life of ZVI extended by 28.57% and the total nitrogen removal efficiency changed from 58.03–72.08 to 63.92–78.33% under ultrasonic irradiation. These phenomena were related to the mechanical force and cavitation of ultrasonic waves. Judging from the characteristics of sludge and ZVI, ultrasound can promote anammox sludge granulation, ease ZVI passivation, and enhance the stability of the entire system. This paper also briefly discusses the impact mechanisms of ultrasound on the ZVI-anammox system. In brief, ultrasound destroys the surface structure of ZVI and thus provides numerous attachment points for microorganisms that improve the performance of the entire system. The proposed ultrasound combined with ZVI is a novel method that has potential for use in large-scale engineering applications in actual sewage treatment after comprehensive analysis.
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BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING
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2022
·Vol. 39
·期 3
·661-669
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IF 1.772
Jin Zhengwei,Yu Changjun,Wang Ruyang,Wei Wei,Jing Yunhuan,Wang Qi
The production of precipitated calcium carbonate (PCC) from carbonate-free minerals and CO 2 from industrial exhaust gas could lower energy consumption and promote CO 2 sequestration. The present study proposes a chemical looping process for the production of PCC from wollastonite (calcium silicate) and CO 2 from industrial exhaust using ammonium chloride as the looping medium; this study also included a pilot setup with a capacity of 3 kg of carbonate per hour to demonstrate the process. The process consisted of three phases: extraction of calcium from the wollastonite with hydrochloric acid; carbonation of the CO 2 in the extract solution in the presence of ammonia to produce calcium carbonate while generating ammonium chloride; and regeneration of hydrochloric acid and ammonia by the decomposition of ammonium chloride. A special air-lift reactor with an integrated settling vessel was designed for the carbonation reaction. The extraction and carbonation conditions were optimized, and fine calcium carbonate with a purity greater than 98% and a particle size of 2 μm was produced. The overall utilization of the calcium from wollastonite and the CO 2 reached 99 and 90%, respectively. This process avoids the high-temperature pyrolysis of limestone and thus consumes less energy. It also sequesters CO 2 from industrial exhaust and is a green and high-performing process for the production of PCC.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
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2022
·Vol. 38
·期 4
·1111-1117
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IF 2.726
Zhang Xiangyu,Bai Shan,Zang Leilei,Chen Xiaoqi,Yuan Xiaoyan
With adjustable amphiphilicity and anionic/cationic charge, biodegradability and biocompatibility, amino acid-based poly(ester amide)s(PEAs) have drawn attention in the research of tissue engineered vascular grafts. In this work, L -phenylalanine-based PEAs with or without L -lysine were synthesized through polycondensation, and ultrafine fibrous grafts consisted of PEAs and poly( ε -caprolactone)(PCL) in given mass ratios were further prepared via blend electrospinning. Surface characterizations by Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy confirmed the chemical structure, and the wettability indicated that the prepared PCL/PEAs electrospun membranes exhibited less hydrophobic than PCL. Tensile results showed that the PCL/PEAs membranes possessed suitable mechanical properties, which could meet the requirements of artificial blood vessels. Cell culture and hemolytic tests exhibited that the PCL/PEAs electrospun membranes are biocompatible. In general, the electrospun grafts of PCL/PEAs could be applied for vascular repair.
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Journal of Pharmaceutical Innovation
·
2022
·Vol. 17
·期 4
·1305-1313
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IF 2.538
Lu Shao Hua,Zhang Ming Cai,Zhai Hong Lin,Bi Ke Xin,Zhao Bing Qiang
Purpose Due to the large number of chemical components in Chinese patent medicine, the quality control analysis is faced with greater challenges. Although different detection techniques, analytical conditions, and sample pretreatments are often employed respectively to quantify the multiple target components in complex mixtures, it is difficult to meet the practical requirement of productive enterprises. Methods Tchebichef moments (TMs) were calculated from the raw HPLC–DAD spectra of samples and the linear quantitative models were established by stepwise regression for the eight active components (four alkaloids, one statin, and three glycosides) in Daizongfang (one kind of Chinese patent medicines), respectively. Results The correlation coefficients of prediction ( \({R}_{p}^{2}\) ) were higher than 0.9159, and the spiked recovery rates were from 93.4 to 108.2%. Compared with the N-PLS and MCR-ALS models, the TM models are more accurate and reliable. Conclusions This study not only indicates that chemometrics approach has outstanding advantages for the identification of complex signal, but also provides another way for the rapid analysis of quality control in production.
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Advanced Composites and Hybrid Materials
·
2022
·Vol. 5
·期 2
·1268-1279
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IF 11.806
Su Ji-Ling,Wang Juan,Fu Xiao-Na,Hou Li,Zhu Ping,Zhang Kai,Li Huo-Wang,Hou Ying,Liu Xiang-Yi,Xu Juan
This study explored the physicochemical properties, fatty acid compositions, and thermal characteristics of Malania oleifera seed oil (MOSO). Our data showed that the refractive index and specific gravity of MOSO at ambient temperature were 1.461 and 0.913, respectively. The oil content, acid, peroxide, saponification, iodine value, average molecular weight, and an average number of carbon–carbon double bond per triglyceride were 47.8%, 3.62 mg KOH/g oil, 4.61 meq O 2 /kg oil, 163.16 mg KOH/g oil, 104.28 g I 2 /100 g oil, 1031.51 g/mol, and 4.24, respectively. The fatty acid profiles of the methyl esters showed the presence of 96.09% unsaturated fatty acids and 2.16% saturated fatty acids. Nervonic acid (NA) was the major component (45.04%). These results suggested that MOSO is an excellent source of essential fatty acids and NA and may be used as a potential NA resource of health supplements and medicines. Graphical abstract
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Food Analytical Methods
·
2022
·Vol. 15
·期 5
·1356-1367
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IF 3.498
Gu Yu-Xin,Yan Tian-Ci,Yue Zi-Xuan,Li Min-Hui,Zheng Hui,Wang Shu-Ling,Cao Jun
A novel dispersive micro-solid-phase extraction (DMSPE) method is established for the determination of seven acaricides (clofentezine, benzomate, fenpyroximate, diafenthiuron, pyridaben, doramectin, and ivermectin) in fruit juice and functional food by ultra-high-performance liquid chromatography. In this method, these analytes were extracted from apple juice and curcuma wenyujin using cucurbituril used as the adsorbent, water as the extraction solvent, and methanol as the elution solvent. The primary parameters affecting the extraction efficiency were optimized by experiments for concentration of adsorbent, oscillation time, desorption solvent, and pH value and by response surface methodology. Under the optimal conditions, all target analytes had a good linear relationship, with correlation coefficients ranging from 0.9900 to 0.9940, the limits of detection were 0.42–5.16 ng/mL, the limits of quantification were 1.39–17.18 ng/mL, and the spiked recoveries of seven target compounds in real samples ranged from 70.04 to 94.95%. The intra-day precision RSD variations ranged from 0.13 to 0.70%, and the inter-day precision RSDs were between 0.38 and 1.4%, which had good reproducibility and repeatability. In general, DMSPE is a convenient, efficient, and environmentally friendly method for sample preparation, which has the potential for microextraction.
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ACTA PHARMACOLOGICA SINICA
·
2022
·Vol. 43
·期 9
·2289-2301
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IF 7.169
Su Xue-ling,Wang Shu-hui,Komal Sumra,Cui Liu-gen,Ni Rui-cong,Zhang Li-rong,Han Sheng-na
Connexin 43 (Cx43) is the most important protein in the gap junction channel between cardiomyocytes. Abnormalities of Cx43 change the conduction velocity and direction of cardiomyocytes, leading to reentry and conduction block of the myocardium, thereby causing arrhythmia. It has been shown that IL-1β reduces the expression of Cx43 in astrocytes and cardiomyocytes in vitro. However, whether caspase-1 and IL-1β affect connexin 43 after myocardial infarction (MI) is uncertain. In this study we investigated the effects of VX765, a caspase-1 inhibitor, on the expression of Cx43 and cell-to-cell communication after MI. Rats were treated with VX765 (16 mg/kg, i.v.) 1 h before the left anterior descending artery (LAD) ligation, and then once daily for 7 days. The ischemic heart was collected for histochemical analysis and Western blot analysis. We showed that VX765 treatment significantly decreased the infarct area, and alleviated cardiac dysfunction and remodeling by suppressing the NLRP3 inflammasome/caspase-1/IL-1β expression in the heart after MI. In addition, VX765 treatment markedly raised Cx43 levels in the heart after MI. In vitro experiments were conducted in rat cardiac myocytes (RCMs) stimulated with the supernatant from LPS/ATP-treated rat cardiac fibroblasts (RCFs). Pretreatment of the RCFs with VX765 (25 μM) reversed the downregulation of Cx43 expression in RCMs and significantly improved intercellular communication detected using a scrape-loading/dye transfer assay. We revealed that VX765 suppressed the activation of p38 MAPK signaling in the heart tissue after MI as well as in RCMs stimulated with the supernatant from LPS/ATP-treated RCFs. Taken together, these data show that the caspase-1 inhibitor VX765 upregulates Cx43 expression and improves cell-to-cell communication in rat heart after MI via suppressing the IL-1β/p38 MAPK pathway.
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MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 3
·1-10
·
IF 6.408
Wang Lijun,Zhou Hong,Wu Xue,Song Yanfei,Huang Yukun,Yang Xiao,Chen Xianggui
A novel colorimetric aptasensor has been developed for highly sensitive tetracycline (TC) detection based on the peroxidase-like activity of Fe 3 O 4 @Cu nanoparticles and “sandwich” oligonucleotide hybridization. The Fe 3 O 4 @Cu nanoparticles with high peroxidase-like activity were successfully synthesized under mild conditions. Then, a “sandwich” oligonucleotide hybridization probe (a short amino-modified complementary sequence of a portion of the TC aptamer (cDNA1), TC aptamers, and a long complementary to 5′ terminal TC aptamer sequence (cDNA2)) was created in 96-wells plates via DNA hybridization in the absence of TC from the detection system. The unique “sandwich” oligonucleotide hybridization probe adsorbed large numbers of Fe 3 O 4 @Cu nanozymes while further enhancing its peroxidase-like activity. Based on the 3,3′,5,5′-tetramethylbenzidine (TMB)-hydrogen peroxide (H 2 O 2 ) reporting system, the blue color of the solution decreased linearly with the increase of TC concentration, ranging from 10 −3 to 10 3 μg/L with an ultralow limit of detection (LOD) of 0.91 ng/L (2 pM). The proposed method was successfully applied to detect TC in spiked milk samples, with recoveries of 81.8 to 112%, demonstrating the excellent potential for highly sensitive TC detection in milk. Graphical abstract
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npj Science of Food
·
2022
·Vol. 6
·期 1
·1-8
·
IF 7
Chen Yu-Hong,Zhang Yan-Hong,Chen Gen-Sheng,Yin Jun-Feng,Chen Jian-Xin,Wang Fang,Xu Yong-Quan
Phenolic acids are important taste components in green tea. The aim of this study was to analyze the taste characteristics of phenolic acids and their influence on the bitterness and astringency of green tea by sensory evaluation and chemical determination. The major tea phenolic acids and quercetin-3- O -rutinoside (Que-rut) were significantly positively correlated with the bitterness ( r = 0.757, p < 0.01; r = 0.605, p < 0.05) and astringency ( r = 0.870, p < 0.01; r = 0.576, p < 0.05) of green tea infusion. The phenolic acids have a sour and astringent taste, whereas Que-rut has a mild astringent taste. Phenolic acids and Que-rut can increase the bitterness of epigallocatechin gallate (EGCG). However, these components behaved differently for astringency on EGCG. Gallic acid (GA) enhances the astringency throughout all the concentrations in this study. While it seemed to be double effects of caffeic acid (CA), chlorogenic acid (CGA), and Que-rut on that, i.e., the inhibition at lower concentrations (CA: 0–0.2 mM; CGA: 0–0.2 mM; Que-rut: 0–0.05 mM) but enhancement at higher ones. The phenolic acids and Que-rut interacted synergistically with tea infusion and as their concentration increased, the synergistic enhancement of the bitterness and astringency of tea infusion increased. These findings help provide a theoretical basis for improving the taste of middle and green tea.
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CELLULOSE
·
2022
·Vol. 29
·期 3
·1419-1433
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IF 6.123
Huang Ting,Zhou Yaohong,Zhang Xiaohua,Peng Dayong,Nie Xuliang,Chen Jing,Xiong WanMing
A furfuryl alcohol resin-based solid acid (SC-FAR-800) was prepared and applied in the conversion of carbohydrates into furan platform compounds in microwave. The results showed that SC-FAR-800 was an irregular mesoporous material containing sulfonic acid groups with an acid density of 3.43 mmol/g, which was quite stable below 200 °C. SC-FAR-800 showed good catalytic activity, and the yield of furfural from xylose could reach 60.46%; the yield of 5-HMF from fructose, glucose, cellobiose and cellulose macromolecules could reach 89.35%, 38.17%, 42.6%, 14.73%, respectively. However, the effect of reaction temperature, reaction time, catalyst dosage and water content on various carbohydrate’s conversion was different. SC-FAR-800 could be reused more than 6 times in fructose conversion, and could be regenerated after a re-sulfonation process. Moreover, the catalytic activity of SC-FAR-800 was super to some biomass-based solid acid. Therefore, this catalyst may be an attractive alternative in the conversion of biomass to prepare furan compounds. Graphical abstract Furfuryl alcohol resin-based solid acid (SC-FAR-800), which has a high acidity of 3.43 mmol/g, was applied in the conversion of carbohydrates in a microwave oven. The peak yield of furfural from d -xylose could reach 60.46%; the yield of 5-HMF from d -fructose, glucose, cellobiose and cellulose macromolecules could reach 89.35%, 38.17%, 42.6%, 14.73%, respectively.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2022
·Vol. 29
·期 28
·43169-43178
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IF 5.19
Piao Mingyue,Du Hongxue,Sun Yuwei,Teng Honghui
Hybrid hydrogel was synthesized by immobilizing TiO 2 in polyethylene glycol diacrylate (TiO 2 @PEGDA) as an efficient adsorbent with photocatalysis property for bisphenol A (BPA) elimination. TiO 2 @PEGDA exhibited spherical and rough structure with limited crystallinity and abundant functional groups. The contact angle increased to 61.96° (TiO 2 @PEGDA) from 46.73° (pristine PEGDA), indicating that hydrogel hydrophilicity decreased due to the presence of TiO 2 . The swelling capacity of TiO 2 @PEGDA (9.0%) was decreased compared with pristine PEGDA (15.6%). Adsorption results demonstrated that the maximum adsorption capacity of TiO 2 @PEGDA (101.4 mg/g) for BPA was slightly higher than that of pristine PEGDA (97.68 mg/g). The adsorption capacity was independent with pH below 8 and decreased obviously when the value of pH was higher than 8. The adsorption behavior was fitted well with the pseudo-second-order kinetic and the Langmuir isotherm model. Both ΔG 0 and ΔH 0 were negative, indicating that BPA adsorbed on TiO 2 @PEGDA was an exothermic and spontaneous process. Regeneration study was performed by photocatalysis, and the adsorption capacity was 85.6% compared with the initial capacity after four-cycle use, indicating that TiO 2 @PEGDA could be recycled without significant adsorption capacity loss. Consequently, TiO 2 @PEGDA can serve as an eco-friendly and promising material for efficiently adsorbing BPA with self-clean property.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2022
·Vol. 20
·期 1
·1-22
·
IF 9.429
Zhang Yu,Wang Xiaowei,Chen Jian,Qian Dingfei,Gao Peng,Qin Tao,Jiang Tao,Yi Jiang,Xu Tao,Huang Yifan,Wang Qian,Zhou Zheng,Bao Tianyi,Zhao Xuan,Liu Hao,Zheng Ziyang,Fan Jin,Zhao Shujie,Li Qingqing,Yin Guoyong
Subtalar osteoarthritis (STOA) is often secondary to chronic ankle sprains, which seriously affects the quality of life of patients. Due to its etiology and pathogenesis was not studied equivocally yet, there is currently a lack of effective conservative treatments. Although they have been used for tissue repair, platelet-rich plasma-derived exosomes (PRP-Exo) have the disadvantage of low retention and short-lived therapeutic effects. This study aimed to determine whether incorporation of PRP-Exo in thermosensitive hydrogel (Gel) increased their retention in the joint and thereby playing a therapeutic role on STOA due to chronic mechanical instability established by transecting lateral ligaments (anterior talofibular ligament (ATFL)/calcaneal fibular ligament (CFL)). PRP-Exo incorporated Gel (Exo-Gel) system, composed of Poloxamer-407 and 188 mixture-based thermoresponsive hydrogel matrix in an optimal ratio, was determined by its release ability of Exo and rheology of Gel response to different temperature. The biological activity of Exo-Gel was evaluated in vitro, and the therapeutic effect of Exo-Gel on STOA was evaluated in vivo. Exo released from Exo-Gel continuously for 28 days could promote the proliferation and migration of mouse bone mesenchymal stem cells (mBMSCs) and chondrocytes, at the same time enhance the chondrogenic differentiation of mBMSCs, and inhibit inflammation-induced chondrocyte degeneration. In vivo experiments confirmed that Exo-Gel increased the local retention of Exo, inhibited the apoptosis and hypertrophy of chondrocytes, enhanced their proliferation, and potentially played the role in stem cell recruitment to delay the development of STOA. Thus, Delivery of PRP-Exo incorporated in thermosensitive Gel provides a novel approach of cell-free therapy and has therapeutic effect on STOA.Graphical Abstract
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