JOURNAL OF CONTROLLED RELEASE
·
2020
·
IF 7.727
Tao Sun,Guangping Zhang,Zhongyuan Guo,Qinjun Chen,Yujie Zhang,Yongchao Chu,Qin Guo,Chao Li,Wenxi Zhou,Yiwen Zhang,Peixin Liu,Hongyi Chen,Haijun Yu,Liping Jiang,Chen Jiang
Chelating Cu from tumors has been verified as an effective and promising strategy for cancer therapy through antiangiogenesis. However, systematic removal Cu by injecting with Cu chelators will result unavoidable side effects, since Cu is indispensable to the body. In this work, a micelle targeting to tumors' newborn vessels based on a polypeptide was developed to co-load DOX and Probe X, which can go through an “OFF-to-ON” procedure to report the Cu + -capture events in vivo in a real-time way by giving near infrared (NIR) fluorescence and photoacoustic signal. By co-delivering antiangiogenesis and chemotherapeutic reagents, the tumor can be significantly suppressed, meanwhile with a low systematic toxicity. Hopefully, this work can offer new insights in designing sophisticated antitumor strategy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Packaging and Shelf Life
·
2020
·
IF 4.244
Jie Zhang,Chenglin Cao,Shaoming Zheng,Wei Li,Baobi Li,Xiaoling Xie
Poly (butylene adipate- co -terephthalate) (PBAT)/ magnesium oxide (MgO)/ silver (Ag) ternary composite biofilms were prepared via a common solvent casting method and used for food packaging. The effects of MgO/Ag nanoparticles (NPs) on the physical and antibacterial properties of the composite biofilms were comprehensively investigated. The physical properties of the PBAT matrix, such as the mechanical and barrier properties, are improved by the incorporation of MgO/Ag NPs. The composite films with 3 wt% NPs content exhibit the optimal properties. Specifically, the tensile strength, the elongation at break, water barrier property, and oxygen barrier property are 11.91 MPa, 415.63 %, 1.135 kg·m/m²·s·Pa, and 3.679 Barrer, respectively. Furthermore, the inhibition rates of ternary composite film against Escherichia coli and Staphylococcus aureus exceed 90 %, indicating potential for application in the food packaging industry.
✓ 已验证
DOI
高影响因子
Polymer Chemistry
·
2020
·Vol. 11
·期 31
·5057-5066
·
IF 5.342
Jianrui Zhang,Xiaocui Han,Cheng Yue,Di Liu,Ziyu Lin,Yirong Sun,Liyuan Chen,Jinhui Pang,Zhenhua Jiang
A new diamine monomer with a dioxinyl bipyrimidine group was synthesized. Polyimide containing a bipyrimidine group was successfully homopolymerized by chemical imidization. Analyses to determine the structure and properties of these polymers were conducted using 1H NMR and FTIR spectroscopy and gel permeation chromatography (GPC). For the first time, cobalt acetate was incorporated into the synthesized polyimide to fabricate cobalt-complexed polyimide thin film composite membranes (TFCMs) by spin coating. To fully understand the behavior of cobalt complexed TFCMs, these membranes were synthesized and then characterized by FTIR spectroscopy, X-ray diffraction (XRD), and differential scanning calorimetry (DSC) to survey the effects of cobalt acetate on polyimide. The morphologies of TFCMs were determined using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). Phase separations and defects were absent in all cobalt-complexed TFCMs; the average thickness of the films ranged from 550 to 600 nm. This strongly suggested that cobalt acetate has good compatibility with bipyrimidine polyimide. The gas separation performance for TFCMs was also determined with the following results: the CO2 permeance of DMD-PI-3.0 (mixing 3.0 wt% cobalt acetate) TFCMs was 69.9 GPU at 35 °C and 1.5 bar while the selectivity of CO2/CH4 was 44.79 for DMD-PI-15 TFCMs. In short, this work reports a promising method to utilize the separation characteristics of polyimide TFCMs by incorporating cobalt ions.
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale
·
2020
·Vol. 12
·期 27
·14863-14869
·
IF 6.895
Shuli Yin,You Xu,Songliang Liu,Hongjie Yu,Ziqiang Wang,Xiaonian Li,Liang Wang,Hongjing Wang
The development of doped noble metal catalysts with nonmetal elements to improve the catalytic performance toward the oxygen reduction reaction (ORR) is significant for proton exchange membrane fuel cell technology. Here, we report a one-pot for dual-nonmetal-doping strategy for the synthesis of S and P-co-doped mesoporous PtPd nanocages (PtPdSP mNCs) by using pre-synthesized mesoporous PtPd nanocages (PtPd mNCs) as the precursor and triphenylphosphine sulphide as both S and P sources. Benefitting from the combined advantages of metal–nonmetal incorporation, hollow cavity and surface porosity, the resultant quaternary PtPdSP mNCs exhibit outstanding ORR activity and long-term stability. This research work provides a good strategy for the doping of two or more selected nonmetallic elements into metallic nanocrystals with a controllable structure and composition.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
HYDROMETALLURGY
·
2020
·
IF 3.338
Xintao Yi,Guangsheng Huo,Wei Tang
The extraction of Fe(III), Ni(II) and Co(II) from a Ni(II)-Co(II) solution containing Fe(III) was analyzed in a chloride medium using a mixed extractant consisting of 50% ( v /v) tributyl phosphate (TBP), 20% (v/v) 2-octanol and 30% (v/v) kerosene. The extraction of 0.5 mol/L Fe(III) in 4 mol/L hydrochloric acid reached 97%, and the consumption of chloride ions was investigated. Nickel(II) ions were not detectably extracted by TBP, with an inclusion of <1.1%. Compared with Fe(III), TBP extracted only a small amount of Co(II). The iron complexes formed by TBP and 2-octanol were [H 2 FeCl 4 · 2TBP] and [H 2 FeCl 4 · 5(2-octanol)], and the possible compositions of Co-containing extracts were [H 2 CoCl 4 · 2TBP] and [H 2 CoCl 4 ] · n[2-octanol]. An industrial process consisting of two-step extraction was designed to achieve the separation of Co(II) and Fe(III), resulting in a decrease in the Fe/Co mass ratio from 0.46 to <3.5 × 10 −4 in the raffinate.
✓ 已验证
产品关联
DOI
高影响因子
JOM
·
2020
·Vol. 72
·期 3
·1279-1285
·
IF 2.054
Xia Yang,Zhao Jinlong,Dong Zhaowang,Guo Xueyi,Tian Qinghua,Liu Yong
Cobalt-chrome-molybdenum (Co-Cr-Mo) alloy possesses outstanding strength, wear, and corrosion resistance and is a good material candidate for making dental and orthopedic implants. Spherical Co-Cr-Mo powder for additive manufacturing is usually costly due to the high-temperature melting processes and low yield of the powder with desirable particle size in the conventional melt-atomization process. A novel process for making spherical Co-Cr-Mo alloy powder through a simple meltless granulation and sintering process is described herein. The results indicate that the compositional segregation problem can be overcome and high-temperature operation avoided. Segregation-free powder was obtained after sintering above 1200°C. The powder was purified during sintering in a hydrogen atmosphere. The hydrogen purification mechanism is discussed with the aid of thermodynamic modeling using HSC Chemistry software. The oxygen content in the final powder can be controlled to < 0.2 wt.% for powder with particle size < 107 µ m. The final powder retained good spherical morphology.
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2021
·Vol. 413
·期 25
·6303-6312
·
IF 4.157
Wan Hui,Cao Xiyue,Liu Min,Zhang Feifei,Sun Chao,Xia Jianfei,Wang Zonghua
To improve the efficiency of aptasensors, a signal amplification strategy by coupling tyrosinase (Tyr)–triggered redox cycling with nanoscale porous carbon (NCZIF) has been proposed. The NCZIF was obtained by calcining ZIF-8 crystals in an inert atmosphere. It had high surface areas, great biocompatibility, and ease of functionalization, which was beneficial for immobilizing sufficient Tyr and aptamer covalently. When the target prostate-specific antigen (PSA) was present, the NCZIF functionalized with Tyr and an aptamer bound to the aptamer-modified Au electrode specifically through the sandwich structure. Then, Tyr acted to oxidize the electroinactive phenol, which led to low-background signal, in the substrate to electroactive catechol, and triggered the redox cycling under the action of NADH. The low detection limit of the proposed electrochemical aptasensor for PSA was 0.01 ng mL −1 , and the wide detection range was from 0.01 to 50 ng mL −1 . The use of ZIF-8 derived porous carbon and Tyr-triggered redox cycling system provided a promising solution for the development of simple, rapid, reliable, and low-background aptasensing methods, which had great potential in the field of disease diagnosis and biomedicine. Graphical abstract
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CHEMISTRY
·
2021
·Vol. 39
·期 10
·2801-2807
·
IF 6
Mengdi Zhang,Xiaofeng Lei,Yang Lv,Xizheng Liu,Yi Ding
Main observation and conclusion The application of lithium-ion batteries in cold climates has been hindered due to the decline in performance at low temperatures. The increased de-solvation energy and formation of Li dendrites at the anode surface emerge as the major challenges, which rely on the development of stable anode and compatible electrolytes. Herein, a self-healing GaInSn liquid metal (LM) based electrode coupled with a multi-solvent electrolyte is proposed toward reversible Li-storage at low temperatures. By using methyl butyrate (MB) as a co-solvent in 1 mol·L –1 LiTFSI of ethylene carbonate and diethyl carbonate, the electrolyte viscosity decreases from 52.07 to 13.75 mPa·s, while the ionic conductivity increases from 1.38 to 3.44 mS·cm –1 at –20 °C. Moreover, the Li/MXene@LM cells can display a discharge capacity of 500 mAh·g –1 , with capacity retention of 78% at –20 °C after 120 cycles. It is disclosed that a uniform LiF-rich solid electrolyte interface (SEI) layer on the anode is formed upon the addition of MB, which promotes the desolvation of Li ions at the interface of electrode/electrolyte especially at low temperatures. These results prove that MB as the co-solvent is well compatible with LM based anodes and holds great potential for the exploration of low-temperature energy devices.
✓ 已验证
产品关联
DOI
高影响因子
OPTICAL MATERIALS
·
2021
·
IF 3.08
Peiyuan Zhu,Zhijun Zhu,Zhenhua Li,Yanan Xu,Laurence A. Belfiore,Jianguo Tang
Carbon dots with both red-emission and red-excitation (R-CDs) have attracted much attention due to their excellent optical property and promising application in various fields. However, most carbon dots (CDs) with red-emission are only excited with short wavelength irradiation, which heavily hinders their further applications. Herein, novel R-CDs are obtained through a hydrothermal synthesis by using p-phenylenediamine and ammonium thiocyanate as precursors. The as-synthesized R-CDs exhibit a strong red emission at 618 nm at a long excitation (598 nm). Moreover, the R-CDs are explored as a selective and sensitive “turn-off” sensor for Sn 2+ detection by the non-radiative recombination of the excitons through effective electron, charge or energy transfer between Sn 2+ and surface functional groups such as hydroxyl, carbonyl, amine, thiophene, and S O, with a detection range from 0 to 90 μM and a detection limit of as low as 17.25 nM.
✓ 已验证
产品关联
DOI
高影响因子
Food Packaging and Shelf Life
·
2021
·
IF 6.429
Jie Zhang,Chenglin Cao,Yibo Wang,Lan Xie,Wei Li,Baobi Li,Ruijie Guo,Hong Yan
Magnesium oxide (MgO)/ silver (Ag) nanoparticles (NPs) were synthesized and incorporated into poly(butylene succinate- co -terephthalate) (PBST) matrix to prepare PBST/MgO/Ag nanocomposite films by solvent casting. The effects of nanofillers on physical, antibacterial, and cherry tomato preservation properties of the PBST matrix were studied. The introduction of nanofillers effectively enhanced the thermal, mechanical, and barrier properties of the PBST matrix. Optimal properties were achieved by 3% (w/w) MgO/Ag NPs content. Their initial decomposition temperature, elongation at break, tensile strength, water vapor permeability, and oxygen transmission rate were 343.3 °C, 544.94 %, 31.57 MPa, 1.61 × 10 −11 g•m/m 2 •s•Pa, and 4.01 × 10 −11 Barrer, respectively. Owing to the enhanced antibacterial activities of the nanofillers, PBST/MgO/Ag possessed superior antibacterial activities against Gram-positive bacteria ( Staphylococcus aureus ) and Gram-negative bacteria ( Escherichia coli and Salmonella para-typhi B ). Cherry tomato preservation experiments proved the excellent preservation capability of PBST/MgO/Ag films. These findings indicated that the nanocomposites possessed potential prospects in packaging.
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Muntadher M. Alwan Almijbilee,Yifei Wang,Mao Peng,Aiqun Kong,Jinli Zhang,Wei Li
A new nanofiltration composite membrane poly (butyl acrylamide-co-divinylbenzene) (poly-TaDb) was synthesized via a facile photopolymerization on polyetherimide using the monomers of n- tert -butyl acrylamide and divinylbenzene, and evaluated the separation performance in organic solutions. The unique poly-TaDb toplayer has a feature of branch structure containing regularly distributed oxygen and nitrogen groups that work as the interacting sites with metal ions (Fe 3+ , Zn 2+ , and Cu 2+ ), as reflected by the characterizations of ATR-FTIR, XPS, AFM, etc. Without the metal ion treatment, the optimal poly-TaDb membrane shows the permeance of 31, 17, 20.4 L m −2 h −1 MPa −1 respectively for organic solutions of tetrahydrofuran (THF), methanol (MeOH) and acetonitrile (ACN), with the rejection rates higher than 90% toward EB dye (879.8 g.mol −1 ). After interacting with these metal ions, the obtained Fe-binding poly-TaDb membranes possess higher permeance, with the THF, MeOH, and ACN permeance enhanced respectively to 113, 35, and 24.2 L m −2 h −1 MPa −1 , meanwhile maintaining high dye rejection rate. While the Cu- and Zn-binding membranes show much higher permeance but lower dye rejection rate. Density functional theory (DFT) calculations disclose that the void size of the toplayer network increases in the order of: the pristine (11.40 Å) < Fe-binding (11.54 Å) < Zn-binding (11.60 Å) < Cu-binding membrane (11.63 Å). It is the suitable void size and charge density distribution in the toplayer network of Fe-binding membrane. that results in the superior nanofiltration performance. This work provides a facile route to explore new polymeric network materials for highly effective separation performance in organic solvents.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2021
·
IF 5.816
Wenkai Huang,Fuhua Xu,Xiang Liu
Sodium borohydride has been widely regarded as a promising hydrogen carrier owing to its greatly hydrogen storing capability (10.8 wt%), high weight density and excellent stability in alkaline solutions. Herein, we first design and synthesize a series of bimetallic M-Ru/C nanocomposites (including Fe–Ru/C, Co–Ru/C, Ni–Ru/C and Cu–Ru/C), via simply alloying of commercial Ru/C with nonprecious metal, for superior H 2 evolution from the NaBH 4 hydrolysis. The result exhibits that H 2 generation is synergetically improved by alloying Ru/C with Co or Ni, while it is hindered by alloying Ru/C with Fe or Cu. Indeed, Co–Ru/C presents the highest efficient catalytic activity for H 2 generation, with the TOF of 117.69 mol(H 2 )·mol Ru −1 ·min −1 , whereas Ru/C is only 57.08 mol(H 2 )·mol Ru −1 ·min −1 . In addition, the TOF of Co–Ru/C reaches to 436.51 mol(H 2 )·mol Ru −1 ·min −1 (96.7 L(H 2 )·g Ru −1 ·min −1 ) in the presence of NaOH.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）