ADVANCED FUNCTIONAL MATERIALS
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2025
·
IF 19
Yun Li,Zhuorui Dong,Yingfei Ma,Jian Zhang,Yanan Wang,Dandan Cui,Kaifang Wang,Baojie Du,Runzhi Li,Zhifei Wang,Ruixue Wang,Bing Cao,Ruiping Zhang
Acinetobacter baumannii ( A. baumannii ) is a leading cause of pneumonia. Conventional antibiotics can increase the risk of drug resistance and non-specifically harm microflora, disrupting their balance. In addition to pathogenic bacteria, lung inflammation also damages tissue. This study develops an aptamer/polymer-functionalized mesoporous polydopamine/silver nanocomposite (Apt/ODEA-PDA/Ag-ICG) to specifically target A. baumannii and sequentially exhibit antibacterial/antioxidative properties for pneumonia treatment. After synthesizing the polyzwitterion (ODEA), the polymer/aptamer is conjugated with the PDA/Ag core, and ICG is further labeled to fabricate the nanocomposite. Upon intratracheal instillation, nanocomposites penetrate the mucus barrier with the help of polyzwitterions. The nanocomposite precisely targets A. baumannii through specific recognition by the aptamer, without affecting other microflora. Moreover, ICG is conjugated and distributed disorderedly within the polymer. ICG near the PDA/Ag core contributes to high NIR-I absorbance and good photothermal ability. ICG further from the PDA/Ag acts as a fluorescent molecule for specific A. baumannii imaging. Furthermore, PDA/Ag efficiently exhibits synergistic antibacterial activity owing to the acidic environment/heat-accelerated Ag + release and photothermal effect. Importantly, alongside Ag + release, the antioxidant ability of PDA scavenges reactive oxygen species and alleviates inflammation, thereby accelerating pneumonia treatment. In summary, nanocomposites provide an alternative approach for designing advanced antibacterial systems.
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Journal of Energy Storage
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2025
·
IF 9.8
Wenjing Chen,Lan Jiang,Xiaowu Hu
Phase change material (PCM) is a promising energy material for applications, but their inherent drawbacks, such as poor thermal conductivity and vulnerability to leakage, strongly limit their use in efficient energy storage and thermal management. To overcome these drawbacks, this paper innovatively uses a high-temperature one-step reduction method to simultaneously prepare Ag particles and reduced graphene oxide (rGO) and carbonize melamine foam (CMF) to improve thermal conductivity as well as photo-thermal conversion, and ultimately a series of shape-stable thermally conductive reinforced composite phase change material (CPCM) are prepared using vacuum impregnation. The high-density three-dimensional thermal conductivity network of Ag@rGO-CMF was able to significantly increase the thermal conductivity of CPCM (up to 104.2 % enhancement). The prepared CPCM have high loading ratios (96.9 % ~ 97.8 %), high enthalpies (154–157.7 J/g), high photo-thermal conversion efficiencies (81.3 % ~ 90.5 %), and excellent thermal management capabilities of electronic devices. This study provides a simple and feasible method for the preparation for high performance CPCM.
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ANALYTICAL CHEMISTRY
·
2024
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IF 6.7
Jing Wu,Ying Zhang,Jiuchuan Wang,Zhuangzhuang Ling,Xuanhua Yan,Xiaoming Lyu,Jinghuai Fang,Mingfei Cheng,Min Zhao,Tao Ban,Yu Liu,Yang Li
In the realm of disease diagnostics, particularly for conditions such as proteinuria and hemoglobinuria, the quest for a method that combines accurate, label-free detection of protein compositions and their conformational changes remains a formidable challenge. In this study, we introduce an innovative Ag/Au plasmonic hybrid coupling nanoarray (Ag/Au PHCN) architecture marked by sub-10 nm interparticle gaps. These nanoarrays, leveraging plasmonic hybrid coupling and synergistic enhancement mechanisms, create a plethora of uniform surface-enhanced Raman spectroscopy (SERS) hotspots. The Ag/Au PHCN substrates demonstrated unparalleled sensitivity in the unmarked detection of hemoglobin (HGB), bovine serum albumin (BSA), and cytochrome C (Cyt.C) in bodily fluids, incorporating the advantages of high sensitivity, high reproducibility, durability, recyclability, and biocompatibility. Notably, the detection limits for BSA and HGB are unprecedented at 0.5 and 5 ng/mL, respectively. This achievement sets a new benchmark for label-free protein detection using two-dimensional nanostructures. Crucially, the Ag/Au PHCNs possess the novel capability to discern protein conformational changes post denaturation, underscoring their potential in probing protein functionalities. Most importantly, these nanoarrays can differentiate between normal and proteinuria-affected urine samples and monitor protein content variations over time, heralding a new era in clinical diagnostics with particular relevance to proteinuria and hemoglobinuria detection.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
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IF 4.9
Lan Zhang,Tingting Zhang,Shiying Wu,Lujie Li,Wei Li,Lingling Wang,Weihua Li,Xianhuai Huang,Jiansheng Li,Rui Lu
Although surface-enhanced Raman scattering (SERS) is a powerful spectral analysis technique, its practical application is restricted due to the poor chemical stability of some noble metal nanoparticles. In this work, Ag@ZIF-8 nanocomposites with different ZIF-8 core-shell thicknesses were prepared by coating AgNP surfaces with polyvinylpyrrolidone and adjusting the dosage of zinc nitrate and 2-methylimidazole. Several characterizations have confirmed that the Ag@ZIF-8 nanocomposites was successfully prepared. Based on transmission electron microscopy images and SERS spectral intensity, it was determined that Ag@ZIF-8 nanocomposites with a ZIF-8 shell thickness of 30 nm exhibited optimal SERS performance. As a result of evaluating the uniformity and stability of the composite with 4-ATP as the probe molecule, it showed a relative standard deviation of 6.91 % and a decrease in SERS intensity of 4.5 % after 28 days. Based on the results obtained with Ag@ZIF-8 nanocomposites as the SERS substrate, the detection limits of 4-mercaptopyridine and thiram were as low as 5.87×10 −9 M and 6.61×10 −8 M, respectively. Furthermore, the finite-difference time-domain simulation reveals an enhancement factor of 2.6×10 6 , which is in good agreement with the experimental value of 1.8×10 6 , confirming its effectiveness as a SERS substrate.
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BIOCHEMICAL ENGINEERING JOURNAL
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2025
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IF 3.8
Meng Xianghe,Wang Shuyi,Lu Yuanchao,Nie Xiaohua,Ye Qin
Sciadonic acid (△5,11,14–20:3, SCA) is a rare versatile non-methylene-interrupted polyunsaturated fatty acid. To prepare high purity SCA from Torreya oils with 8.04 % purity, Ag + -assisted high-speed countercurrent chromatography (HSCCC) combined with urea complexation (UC) or argentation column chromatography (CC) was investigated. Results showed that n -hexane: acetonitrile (1:1, v/v) was suitable mobile phase for HSCCC, and SCA with purity of 23.74 % and recovery of 61.74 % (SCA purity>20 %) were obtained. When the Ag + addition was 0.50 %, one round of Ag + -HSCCC resulted in a recovery of SCA up to 95.38 % with purity around 21 %. It was believed that the enhanced performance originated from the reversible complexes between Ag + and C C in SCA through π-s * and d-π* bonds. Starting with low purity SCA of 8.04 %, HSCCC (23.74 %), UC (62.67 %), or Ag + -CC (60.41 % ) alone failed to produce SCA with high-purity (>90 %). However, Ag + -HSCCC combined with Ag + -UC or Ag + -CC yielded SCA with purities of 76.21 % and 97.74 %, and overall recovery of 21.38 % and 19.31 %, respectively. Thus, Ag + -HSCCC was an efficient method for the pre-enrichment of SCA, which could effectively facilitate coupling with UC, Ag + -CC or other PUFA purification techniques, resulted in significant improved purification performances.
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BIOSENSORS & BIOELECTRONICS
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2024
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IF 10.7
Chunli Yang,Yanan Shi,Yuqing Zhang,Jiayang He,Zhihan Zhang,Xinyue Jia,Ruo Yuan,Wenju Xu
Constructing label-free bivariate fluorescence biosensor would be intriguing and desired for the recognizable and accurate detection of two specific DNA segments, yet the design of functional DNA structures with low overlapped interference might be challenging. Herein in this work, a double-faced J anus D NA n ano a rchitecture ( J DNA) with bi-responsive recognition regions on opposite sides was assembled, which consisted of two substrate strands and two template strands for loading green-/red-emissive Ag nanoclusters ( g AgNC and r AgNC) as bivariate signaling reporters. Of note, the hybridized double helix in the middle rationally oriented two flank faces and stabilized the rigid conformation of J DNA, while the template sequences of bicolor clusters were blocked to minimize non-specific background leakage. Upon inputting two targets, the discernible hairpins lost their hairpin structures due to forming two dsDNA complexes. They were executed to simultaneously invade J DNA for activating two individual target-recycled strand displacement (TRSD) events, guiding signal transduction and efficient amplification. Consequently, the clustering templates were unlocked via the tailored conformation switch of J DNA, in which g AgNC and r AgNC were in situ synthesized in two diagonal positions, thereby significantly emitting bi-responsive signal without cross interference. Benefited from the logic integration of double-faced J DNA and TRSD, a label-free, sensitive and specific bivariate fluorescence approach was developed, which would open a new avenue for the potential application in biosensing and bioanalysis.
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Analytical Methods
·
2024
·Vol. 16
·期 14
·2085-2092
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IF 2.7
Yue Liu,Guanwen Su,Wei Wang,Hongyuan Wei,Leping Dang
This study proposes a microfluidic platform for rapid enrichment and ultrasensitive SERS detection of bacteria. The platform comprises ZnO nanoflower arrays decorated with silver nanoparticles to enhance the SERS sensitivity. The ZnO nanoflower array substrate with a 3D reticular columnar structure is prepared using the hydrothermal method. SEM analysis depicts the 3.05 μm gap distribution of the substrate array to intercept the most bacteria in the particle sizes range of 0.5 to 3 μm. Then, silver nanoparticles are deposited on the ZnO nano-array surface by liquid evaporation self-assembly. TEM and SEM analysis indicate nanosize of Ag particles, evenly distributed on the substrate, enhancing the SERS efficiency and improving sensing reproducibility. The probe molecules (R6G) are tested to demonstrate the high SERS activity of the proposed microfluidic sensor. Then, Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, and Bacillus subtilis are selected, demonstrating the sensor's excellent bacterial capture and sensitive recognition capabilities, with a detection limit as low as 102 CFU mL−1. Additionally, the antibacterial properties of ZnO/Ag heterojunction nanostructures are studied, suggesting their ability to inactivate bacteria. Compared with the traditional Au-enhanced chip, the sensor preparation is easy, safe, reliable, and low-cost. Moreover, the ZnO nano-array exhibits a large specific surface area, high interception ability, stronger and uniform SERS performance, and effective and reliable detection of trace pathogens. This work provides potential future ZnO/Ag microfluidic SERS sensor applications for rapid, unlabeled, and trace pathogens detection in clinical and environmental applications, potentially achieving breakthroughs in early detection, prevention, and treatment.
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MICROCHEMICAL JOURNAL
·
2025
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IF 5.1
Lei Zhang,Zhen Zhao,Hongming Zhang,Wanli Jiao
To detect trace hydrogen sulfide (H 2 S) safely, more sensitively and less expensively, a new synthesized ZIF-8-derived ZnO-supported Ag nanoparticle assemblies have been investigated. In the successful formation, ZIF-8 was synthesized in room temperature aqueous solution, followed by ultrasonication to produce Ag + /ZIF-8 compounds, and yielded Ag/ZnO assemblies after sintering. Various characterizations have been done to confirm the morphology, surface chemical state and electron distribution by XRD, SEM, XPS, BET and DRIFT. The sensing test results indicate that at an exciting operating temperature of 100 °C, the A-2 labeled sensor exhibits excellent H 2 S detection capabilities, including a response value of 104 for 2.5 ppm H 2 S, the minimum detection limit of 1.1 ppb, satisfied selectivity, significant resilience against humidity and long time stability. More significantly, a valuable test of 140 h real time detection of the H 2 S emission from fresh fish meat has been performed successfully, providing effective data for protein spoilage assessment. Rhombic dodecahedron structure, catalysis of Ag nanoparticles and overflow effect of H 2 S result in the distinct sensing mechanism, providing novel insights and theoretical foundations for developing highly efficient trace H 2 S gas sensors.
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COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2024
·
IF 8.1
Yanzhi Cai,Dengpeng Chen,Laifei Cheng,Siyu Guo,Zhongyi Hu,Yuhan Wang,Haiming Yu,Yuan Zhou
The performance of sensors is often limited by the structural characteristics of the single form of conductive filler, making it difficult for sensors to simultaneously consider the broad sensing range and high sensitivity. How to achieve high sensitivity and broad working range of sensors through innovative sensing materials and sensor structure design remains a challenge. Here, a flexible sensor with multidimensional sensing materials and a double-layer structure is constructed. It consists of a high-performance CNTs@Ag-MXene-TPU sensing layer and a TPU flexible layer with significant deformability. Thanks to the synergistic effect of the double-layer structure and multidimensional sensing materials, this sensor has a high sensitivity of up to maximum gauge factor of 12216.3 and a wide sensing range of 300 %. Its response time and recovery time can reach 200 and 250 ms, respectively, and it also exhibits excellent cycling stability.
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ENVIRONMENTAL RESEARCH
·
2024
·
IF 7.7
Jiwen Li,Yaqian Duan,Linlin Wang,Jingjun Ma
The poor light absorption and low carrier separation efficiency of Titanium dioxide (TiO 2 ) limit its further application. The introduction of plasma metal Ag have the potential to solve these drawbacks owing to its plasma resonance effect. Thus core-shell structure Ag@TiO 2 plasma photocatalysts was prepared by using facile reduction method in this work. More specifically, Ag@TiO 2 composite catalysts with different Ag loading amounts were prepared in the presence of surfactant PVP. Ag@TiO 2 demonstrates excellent light absorption performance and photoelectric separation efficiency compared with pure TiO 2 . As a result, it displays excellent performance of Cr(VI) reduction under visible light. The optimal composite catalysts Ag@TiO 2 –5P achieves exceptional visible-light-driven photocatalytic Cr(VI) reduction efficiency of 0.01416 min −1 that is 2.29 times greater than pure TiO 2 . To investigate the role of PVP, we also synthesized Ag@TiO 2 -5 without PVP. The experimental results show that although Ag@TiO 2 -5 Cr(VI) reduction performance is superior to pure TiO 2 , it significantly decreases compared with Ag@TiO 2 –5P. The results of TEM and optoelectronic testing show that agglomeration of Ag particles leads to a decrease in the photoelectric separation efficiency of Ag@TiO 2 -5. The smaller Ag particles provide more active sites and demonstrating a stronger overall local surface plasmon resonance (LSPR) effect. DMPO spin-trapping ESR spectra testing indicates that ∙O 2 − and ∙OH are the main reactive species. This research provides a potential strategy to prepare Ag-based plasma photocatalysts for environment protection.
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Chemosensors
·
2024
·Vol. 12
·期 9
·187
·
IF 3.7
Yuyu Peng,Chunyan Wang,Gen Li,Jianguo Cui,Yina Jiang,Xiwang Li,Zhengjie Wang,Xiaofeng Zhou
In this study, a MOF-199/Ag@Au SERS sensing structure was successfully synthesized by combining metal–organic frameworks (MOFs) with surface-enhanced Raman scattering (SERS) technology for the efficient detection of dopamine (DA), a biomarker for neurological diseases, in serum. Using electrochemical methods, a copper-based MOF (MOF-199) was synthesized in situ on copper substrates and further deposited with silver nanoparticles (AgNPs). Subsequently, gold nanoshells were encapsulated around these silver cores by in situ chemical deposition. This preparation process is simple, controllable, and inexpensive. Furthermore, a novel Azo reaction-based DA SERS method was proposed to detect 1 pM DA, which represents an improvement in sensitivity by two orders of magnitude compared to previous unlabeled SERS detection methods and by four orders of magnitude compared to another SERS approach proposed in this work. There was an excellent linear relationship (R2= 0.976) between the SERS signal at 1140 cm−1and the DA concentration (0.001 M~1 pM). The results indicate that the MOF-199/Ag@Au sensor structure can successfully achieve both the qualitative and quantitative detection of DA in serum, thus providing a robust technical basis for the application of SERS technology in the field of clinical neurological disease screening.
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Desalination and Water Treatment
·
2024
·
IF 1
Songhao Luo,Zhigang Yi,Min Cheng,Biao Song,Chengyun Zhou,Wenjun Wang,Zhifeng Liu
It is challenging to produce soft polymer materials with high surface area and nanoscale morphology that can be used for continuous flow water treatment in a processable, versatile, and stable manner. Here, we manufactured a processable Ag@CMPA-bph and used it to treat pollutants in wastewater at continuous flow conditions. The aerogel was prepared by a simple reduction method of CMP matrix and Ag metal precursors. Thermogravimetric analysis and electron microscopy showed that the aerogel had excellent thermal stability and distribution of fine Ag nanoparticles. The synthesized aerogel inherits the controllable properties of the CMP matrix and can be tailored to a specific shape for installation into the water treatment unit. In continuous flow conditions, this aerogel shows excellent catalytic activity to efficiently treat the combined pollutant containing p- nitrophenol and methyl orange ( p- NP&MO), which can reach a removal rate of more than 99 % at the flow rate of 0.6 L h -1 . Furthermore, the Ag@CMPA-bph can also be used for continuous flow treatment of pollutants in river water sample and shows robust anti-pollution load capacity and catalytic activity.
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