MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 9
·1-10
·
IF 5.705
Sun Ying,Wang Ruixue,Liu Xuan,Shan Guiye,Chen Yanwei,Tong Ti,Liu Yichun
Platinum nanoparticles (PtNPs) were uniformly grown on the surface of gold nanorods (AuNRs) by a laser irradiation procedure. Transmission electron microscopy confirmed that the PtNPs are uniformly grown on the surface of the AuNRs. The formation of PtNPs on the AuNRs leads to a red-shift of the absorption maximum from 734 nm to 766 nm. In addition, the efficiency of surface enhanced Raman scattering (SERS) is increased, but the photothermal conversion efficiency is decreased compared to pure AuNRs. The result indicates that electron transfer occurs between gold and platinum. The peroxidase mimicking effect of PtNPs, AuNRs and Au/Pt NRs by catalyzing the oxidation of colorless 3,3’,5,5’-tetramethylbenzidine (TMB) to blue oxidized 3,3’,5,5’-tetramethylbenzidine (oxTMB; a quinone) in the presence of H 2 O 2 . The catalytic activity of Au/Pt NRs is higher than that of sole AuNRs or PtNPs by factors of 4.2 and 2.1, respectively. Thus, Au/Pt NRs have been used for the detection of peroxide and the limit of detection is 0.04 μM. This work provides an approach to integrate the peroxidase mimicking effect with SERS enhancement for potential application in detection.
A schematic diagram for the laser-induced growth of Au/Pt NRs and the colorimetric determination of hydrogen peroxide concentration with their peroxidase mimicking properties. The limit of detection is 0.04 μM based on the use of Au/Pt NRs as a catalyst.
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TALANTA
·
2018
·
IF 4.244
Linlin Xu,Hua Zhang,Yue Tian,Anxin Jiao,Feng Chen,Ming Chen
The prospect of wielding surface-enhanced Raman spectroscopy (SERS) as a powerful technique for ultrasensitive detection of organic molecules in wastewater has received extensive attention in environmental surveillance. Based on ultraviolet (UV, 405 nm) laser irradiation of ZnO nanorods in HAuCl 4 solution, ZnO@Au nanorods with controllable Au nanoparticles were successfully fabricated and established as an advanced SERS-based substrate. The reduction of Au ions was driven by the generation of electron-hole pairs via UV laser excitation of semiconductor-based nanomaterials , resulting in the moderate overgrowth of Au nanoparticles on the ZnO nanorods. The Au composition-dependent SERS analysis of crystal violet (CV) molecules revealed that the ZnO@Au nanorods with 16.21% Au contents exhibited optimized SERS activity in comparison with other nano-substrates in this paper. Furthermore, the detection limit of light-resistant methyl blue (MB) dye molecules was achieved at nanomole (nM) level of 10 −9 M (0.8 μg/L), providing ultrasensitive detection of organic pollution in wastewater. Even after twenty recycles, the excellent reusability of this novel substrate with 65% original SERS intensity was achieved by subsequently eliminating the residual MB molecules via photocatalytic degradation. Therefore, the as-prepared ZnO@Au nanorods can serve as a cost-effective, clean, reusable and active SERS substrate for ultrasensitive monitoring of light-resistant organic pollutant in natural ecosystems.
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ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Xiaosen Li,Chun Li,Yifan Fang,Xin Liang,Zhou Fang
Chemical agents present significant threat to international peace, security, and human health due to their potential toxicity. Therefore, developing a sensitive, rapid, and on-site detection method is of great importance. Herein, we developed a highly sensitive and selective glove-based electrochemical sensor based on a metal–organic-framework-modified screen printed electrode (SPE) for chemical agent marker detection. Layered copper benzene-1,3,5-tricarboxylate (Cu-BTC) was successfully constructed to modify screen-printed electrodes (SPE) for detecting electrically inactive ethyl methyl phosphonate (EMPA) and isopropyl methyl phosphonate (IMPA). Additionally, gold nanoparticles (AuNPs) reduced by plasma technology have been applied to create gold nanoparticle-encapsulated copper benzene-1,3,5-tricarboxylate-modified screen-printed electrode (Au@Cu-BTC/SPE) composites for detecting thiodiglycol (TDG). The large surface area and porous structure of Cu-BTC and Au@Cu-BTC enhance the target adsorption and ion diffusion and the efficient use of catalytic materials for rapid electron transfer and zero-distance catalysis. The limit of detection (LOD) was determined to be 4.13 × 10–16 M for EMPA, 7.46 × 10–12 M for IMPA, and 4.05 × 10–12 M for TDG. Following multiple cycles and extended exposure, the sensor demonstrated exceptional repeatability and stability. The response current of Cu-BTC to EMPA and IMPA decreased by 6.75% and 4.86%, and the peak value of Au@Cu-BTC to TDG decreased by 3.3% after 4 weeks, respectively. The peak current showed a good linear relationship with the concentrations of the three target substances, with R2 values all greater than 0.99. The interaction mechanism between the modified electrode and the targets was investigated by density functional theory (DFT) with the generalized gradient approximation of the PBE functional. The results showed that compared with other metal ions, Cu2+ could coordinate tighter with organophosphates. The established MOF-modified SPE integrated with a protective glove sensor was applied for the detection of real-world samples and demonstrated a broad spectrum of practical applications.
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Journal of Materials Chemistry C
·
2021
·Vol. 9
·期 28
·9011-9020
·
IF 7.393
Jiangcai Wang,Cuicui Qiu,Hua Pang,Junyu Wu,Mengtao Sun,Dameng Liu
The ultrasensitive surface-enhanced Raman spectroscopy (SERS) detection of trace organic pollutants is an important issue in environmental protection. However, the SERS detection performance easily suffers from poor sensitivity and reproducibility due to the limitations of materials. A high-performance substrate is necessary to control the plasmonic hotspots in a wide spectral range. In this work, a perovskite quantum dot–graphene/nano-Au (PQD–G/Au) composite was designed using the combination of ligand-assisted reprecipitation and spinning coating techniques. The SERS performance of PQD–G/Au composites showed a strong dependence on their synthesis parameters, which was proved by the finite-difference time-domain program simulation. An excellent SERS detection behavior was obtained on the PQD–G/Au composite for rhodamine 6G (R6G) and p-nitrophenol (PNP) with a large linear detection range (10−12 to 10−6 M for R6G and 10−8 to 10−4 M for PNP) and a low detection limit (6.02 × 10−13 M for R6G and 2.95 × 10−9 M for PNP). The superior SERS performance was attributed to the synergistic effect of the electromagnetic enhancement of Au nanostructures and chemical enhancement of PQD–G heterostructures. The proposed method paves a new practical application of other 2D materials and heterostructures for designing a novel PQD-based SERS substrate.
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Journal of the Taiwan Institute of Chemical Engineers
·
2019
·
IF 3.834
Shenhao Yuan,Xushuai Lv,Yiwei Zhang,Yangjin Wu,Chunfeng Mao,Yuming Zhou,Wenxia Chen,Yanyun Wang
A core-shell structure Au-based catalysts mSiO 2 /Au/Co 3 O 4 HS were successfully derived from in-situ growth ZIF-67 hollow spheres, which were synthesized by a one-step soft template method. The samples were characterized by SEM, TEM, EDX, XPS, XRD and BET to confirm its successful preparation and structural features. The catalytic performance of the catalysts were evaluated by liquid phase oxidation of benzyl alcohol to benzaldehyde with O 2 as the oxidant under alkaline conditions. The experimental results illustrated that reaction conditions, including effect of catalyst amount, oxygen flow rate, reaction temperature and reaction time, were optimized to be 40 mg, 50 ml/min, 140 °C and 5 h, respectively. Meanwhile, 55% conversion of benzyl alcohol and 84% selectivitiy to benzaldehyde together with the excellent reusability and stability were achieved under optimal reaction conditions, which was attributed to the core-shell structure leading to the encapsulation of Au NPs and provision of multiple active reaction interface. Based on the intermediates formed from the de-protonation of substrate, a plausible oxidation reaction mechanism with mSiO 2 /Au/Co 3 O 4 HS catalysts was tentatively proposed to study the relationship between structure and catalytic performance.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Haifeng Yao,Changbo Jia,Yongping Dong
Herein, a novel sandwich electrochemiluminescence (ECL) aptasensor was developed based on the resonance energy transfer (RET) with iridium complex doped silicate nanoparticles (SiO 2 @Ir) as energy donor and gold nanoparticles modified TiVC MXene (AuNPs@TiVC) as energy acceptor. Strong anodic ECL signal of SiO 2 @Ir was obtained through both co-reactant pathway and annihilation pathway. Electrochemical results showed that SiO 2 @Ir has good electron transfer rate and large specific surface area to immobilize more aptamers. AuNPs@TiVC apparently quenched the ECL signal of SiO 2 @Ir due to the ECL resonance energy transfer between them. In the presence of kanamycin (KAN), a sandwich type sensor was formed with the aptamer probes as connecters between the donor and the acceptor, resulting in the decrease of ECL intensity. Under the optimal condition, KAN could be sensitively detected in the range of 0.1 pg/mL to 10 ng/mL with a low detection limit of 24.5 fg/mL. The proposed ECL system exhibited satisfactory analytical performance, which can realize the detection of various biological molecules by adopting suitable aptamer.
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Yahui Zhang,Xia Huang,Jiachang Chen,Jiyuan Li,Shen Zhou,Junying Chen
Quantitative analysis of harmful patina components on the surface of bronzeware is crucial as patina can corrode artifacts. Surface-enhanced Raman spectroscopy (SERS) has a common application in surface analysis. However, there exists an absence of documented investigations concerning the quantitative analysis of detrimental patina, particularly the chloride patina. To achieve high sensitivity in targeting harmful patina, we report a fabrication method for constructing Ag/Au alloys in the pores and on the surface of UiO-66 (zirconium 1,4-dicarboxybenzene metal–organic framework) nanomaterials, resulting in Ag/Au/UiO-66 nanoparticle monolayers formed by self-assembly at the oil–water interface. By incorporating them onto the surface of PVA hydrogel, we obtained SERS sensor devices with excellent flexibility, outstanding optical transparency, and ultrahigh activity. These sensor devices efficiently sample irregular surfaces and detect micrometer-scale specimen. They significantly enhance the Raman characteristic peaks of measured objects, facilitating precise analysis of the patina composition on the surface of bronze artifacts. The Raman peak at 118 cm–1 was boosted from 367 to 11,909 for detecting harmful patina, and the enhancement factor of the SERS substrate was calculated to be 3.6 ×1010 for detecting the Raman peak of rhodamine 6G (R6G), which could be easily detected at 610 cm–1 at a concentration of 10–13 mol/L (M). The Raman peaks at 610 cm–1 from the SERS substrate could also be readily detected. By grafting the organic fluorescent group amino-MQAE onto the surface of Ag/Au/UiO-66 nanoparticles (NPs), the content of harmful patina on the surface of bronze artifacts treated for different durations was indirectly determined. These results indicate the successful construction of the Ag/Au alloy on the surface of UiO-66 NPs, resulting in SERS sensor devices with excellent flexibility, optical transparency, and ultrahigh sensitivity.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Shengqiao Gao,Qingyi Wei,Hongbin Pu
Heterojunction-like substrates have drawn significant attention in surface enhanced Raman spectroscopy (SERS) owing to their multi-enhancement characteristics. In this study, the core-shell architectures of UiO-66@ TiO 2 were fabricated for capture and enrichment of organophosphorus pesticides (OPs) in solution. After absorption of OPs, the SERS-active nanoparticles of Au were assembled on the core-shell architectures to form UiO-66@TiO₂/Au substrate via Au-S bonding between OPs molecule and AuNPs and electrostatic interactions between UiO-66@TiO 2 and Au, resulting in adsorption-induced aggregation of Raman signal for OPs. The proposed method of adsorption-induced aggregation could be used for detecting thiamethoxam and triazophos in apple juice with detection limit of 3.51 μg/L and 0.66 μg/L, respectively. Furthermore, the satisfactory recovery rates, ranging from 91.98 % to 104.31 % for thiamethoxam and from 91.47 % to 116.47 % for triazophos, indicated that the prepared heterojunction-like substrate could be potentially used for trace detecting OPs in foods.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Sicheng Xu,Hanyan Zhang,Zhiyi Qian,Weizhong Yuan
A novel and efficient cancer therapy was developed using a smart hydrogel containing multifunctional bimetallic organic frameworks and anticancer drugs. The injectable self-healing hydrogel with pH-responsiveness was constructed through borate ester and imine bonds among dopamine-grafted sodium alginate (SADA), hydroxypropyl chitosan (HPCS) and 2-formylphenylboronic acid (2-FPBA). The Au nanoparticles-decorated Ti/Fe bimetallic organic framework tetragonal nanosheets (Au/TF-MOF TNS) were synthesized and incorporated into the hydrogel with the anticancer drugs doxorubicin (DOX). Upon intratumoral injection of nanocomposite hydrogel, the acidic tumor microenvironment triggered the cleavage of borate ester and imine bonds, causing the hydrogel to break down and accelerating the release of both Au/TF-MOF TNS and DOX. These Au/TF-MOF TNS functioned as nanozymes, producing hydroxyl radicals (·OH) for chemodynamic therapy (CDT), generating oxygen (O 2 ) to support sonodynamic therapy (SDT), and depleting glucose for starvation therapy (ST). Additionally, the Au/TF-MOF TNS served as sonosensitizers, capable of converting O 2 into singlet oxygen ( 1 O 2 ) upon ultrasound irradiation to achieve SDT. Therefore, this nanocomposite hydrogel system enabled synergistic sonodynamic-chemodynamic-starvation-chemo therapy (SDT-CDT-ST-CT) of cancer, presenting a promising platform for advanced cancer therapy strategies.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Xiaoyan Ma,Longfei Fu,Ling Zhang,Meiqi Bao,Jie Zhou,Huiting Wang,Qian Zhang,Jiarui Xia
A high-performance flexible surface-enhanced Raman spectroscopy (SERS) substrate has been developed that integrates signal enhancement, self-calibration stability, and photocatalytic self-cleaning functions, enabling reliable SERS detection of organic pollutants in complex environments. The photocatalytically active MoS 2 serves as an intrinsic internal standard (IS) to effectively correct SERS signal fluctuations. The Schottky junction formed between MoS 2 and Au nanoparticles (Au NPs), through the synergistic effect of electromagnetic (EM) and chemical (CM) enhancements combined with localized electric field-induced electron flow, reduces the limit of detection (LOD) for Rhodamine 6G (R6G) to 3.24 × 10 −9 M. Meanwhile, by enhancing the separation efficiency of photogenerated carriers, the substrate achieves efficient self-cleaning within 25 min, demonstrating excellent reusability. For practical application validation, the MoS 2 /Au/filter paper (MoS 2 /Au/FP) flexible substrate was successfully applied to the integrated “wiping, detection and self-cleaning” analysis of 10 −5 to 10 −7 M malachite green (MG) residues on herring surfaces. It maintained stable SERS quantitative performance across multiple rounds of real-sample analysis, verifying its signal reliability for complex matrix detection. This triple-integrated SERS substrate provides novel insights for developing efficient and reliable on-site rapid detection technologies, holding significant application value in food safety monitoring, environmental pollutant analysis, and related fields.
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FOOD CHEMISTRY
·
2026
·
IF 10.4
Yukun Yang,Jian Liu,Rong Guo,Baoqing Bai,Tao Bo,Jinhua Zhang,Ligang Yu,Huilin Liu,Ying Zhang,Shuo Wang
A three-channel sensor array based on Au@Pt NPs was constructed. • Au@Pt NPs with dual-function characteristics was designed. • Discrimination of light aroma-type Baijiu (LAB) was achieved. • Different years, production processes, price gradients, and adulterated were analyzed. • This method highlighted simple to operate, rapid in detection. The development of light aroma-type Baijiu (LAB) industry proposes a growing need for developing rapid and accurate discrimination method for the quality control of LAB. This study innovatively constructed a dual-mode three-channel sensor array based on the gold/platinum nanoparticles (Au@Pt NPs) with surface engineering. In this case, two colorimetric sensor channels based on ascorbic acid/para-aminophenol-chloroauric acid-nanozyme (AA/ pAP-HAuCl₄-Au@Pt NPs) and one fluorescent sensor channel based on nanozyme‑hydrogen peroxide- o -phenylenediamine (Au@Pt NPs-H₂O₂-OPD) were established. Experimental results demonstrate the colorimetric and fluorescence mode can accurately quantify four organic acids and three aldehydes in Baijiu, respectively. Samples including 17 different years and 9 different production processes of basic liquors of LAB, 48 different price gradients of commercial LAB, and adulterated LAB were analyzed. Discrimination with an accuracy exceeding 96% by Linear Discriminant Analysis, Hierarchical Cluster Analysis, and leave-one-out cross-validation was achieved. The dual-mode three-channel sensor array is characterized by simplicity, rapidity and accuracy, providing a new idea for the quality discrimination and market regulation of Baijiu.
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Foods
·
2026
·Vol. 15
·期 15
·2598
·
IF 6
Qingqing Li,Xuecheng Zhang,Shurun Chen,Bowen Guo,Qingwen Cao,Xinyue Feng,Xiaoping Yu,Xiaoyu Jia,Biao Zhang,Hongqing Wang
Acetamiprid (ACE) is a widely used neonicotinoid insecticide with potential health risks due to its persistence in the environment and bioaccumulation in plant-based foods. In this study, an improved dual-mode lateral flow immunochromatography assay (DMLFIA) was established for the sensitive detection of ACE residues in plant-based foods using Au@Ag@Pt NPs as dual-function signal probes. In the colorimetric mode (Mode 1), with the inhibition rate as the vertical coordinate and the ACE concentrations as the horizontal coordinate, the linear detection range of the colorimetric mode was 0.1–3000 μg/L with the detection limit of 0.08 μg/L. In the photothermal mode (Mode 2), the temperature values obtained via smartphones integrated thermal imager showed a linear relationship with 0.1–3000 μg/L of ACE, and the detection limit is 0.1 μg/L. The cross-reactivity rate of the developed DMLFIA with other structural analogs and functional substances was less than 0.39%. The recovery rate of the developed DMLFIA used in spiked plant-based foods was 81.1–99.4%, with relative standard deviations (RSD) of 1.3–10.7%. The detection results of this constructed DMLFIA showed good consistency with those obtained by HPLC and ELISA. The constructed DMLFIA provides a selective, sensitive and rapid detection tool for ACE in different scenarios in plant-based foods.
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