ANALYTICAL LETTERS
·
2026
·
IF 1.8
Panpan You,Lei Li,Wenhui Yang,Shuxin Liang,Taiqun Yang,Chaoqun Ma,Guoqing Chen,Chun Zhu,Hui Gao
The effective treatment of iodine-containing wastewater is essential for environmental protection, as elevated iodide concentrations can adversely affect ecosystems and human health. Traditional methods for iodide monitoring and pH adjustment often involve time consuming multi step procedures, limiting their efficiency in real time wastewater management. In this study, we introduce a deep learning assisted analytical strategy that enables the simultaneous determination of iodide concentration and pH from a single fluorescence lifetime decay curve. The approach is based on the dual sensitivity of fluorescein sodium, which exhibits distinct fluorescence responses in different environments: protonation occurs under acidic conditions, deprotonation under alkaline conditions, and dynamic fluorescence quenching is triggered by iodides. By integrating time correlated single-photon counting (TCSPC) with a hybrid convolutional neural network–residual network–random forest regression (CNN-ResNet-RF) model, we achieve rapid and accurate prediction of both parameters without chemical separation or additional reagents. The proposed model not only overcomes the nonlinear coupling between pH and iodide effects on fluorescence lifetime but also demonstrates strong generalization performance in simulated wastewater matrices. This work provides a robust, reagent-free, and high-throughput analytical platform for real-time monitoring and process control in iodine-containing wastewater treatment.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2026
·
IF 3.1
Xinmei Yan,Junjie He,Ying Yang,Hao Jiang,Haipeng Zou,Zichen Zhang,Guanghao Chen,Yan Jiang,Hongwen Zhang
Oily wastewater poses significant threats to environmental ecosystems and human health, and the inherent complexity of oil–water mixtures underscores the urgent need for advanced, intelligent separation materials. In this study, we report the development of a pH-responsive sponge with reversible wettability switching, designed for efficient and adaptive oil–water separation. Acrylic acid-terminated polydimethylsiloxane (PDMS-AA) was synthesized via sodium ethoxide-initiated ring-opening polymerization of octamethylcyclotetrasiloxane (D 4 ), followed by end-capping with acrylic acid. Subsequently, a bifunctional copolymer (PDMS-AA-UA) was prepared through free-radical copolymerization of PDMS-AA and 10-undecenoic acid (UA), which was then grafted onto hydrophilic SiO 2 nanoparticles to form a micro-/nano-structured composite coating. The resulting sponge exhibits reversible, pH-driven wettability transitions. Under acidic (pH 1) and neutral (pH 7) conditions, the surface displays superhydrophobicity with a water contact angle (WCA) of approximately 160°, enabling selective oil absorption. Upon exposure to alkaline conditions (pH 14), deprotonation of carboxyl groups renders the surface hydrophilic, facilitating rapid release of absorbed oil and demonstrating controllable desorption behavior. This switchable wettability enables on-demand separation of various oil–water mixtures.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2026
·
IF 6.7
Yueyuan Yong,Hafiz Nabeel Ahmad,Lin Chen,Hao Chen,Zhinuo Tang,Jie Zhu
With increasing attention on sustainable biomanufacturing, the stable delivery of natural molecular actives remains hindered by challenges, such as structural instability and low bioavailability. In this study, a stitching strategy based on intermolecular forces to efficiently assemble yeast exopolysaccharides (EPS) into plant-derived soybean isolate protein amyloid fibrils (AF) was proposed. The strategy utilizes hydrogen bonding, hydrophobic interactions, and electrostatic interactions to achieve spontaneous association between EPS and AF. The system could dynamically regulate the release behavior of active ingredients through factors changing, such as pH triggering, thereby achieving an integrated function of loading-protection-delivery. The AF-EPS molecular stitching system significantly enhances the biological activity of polyphenols, provides a new strategy for the efficient delivery and application of natural bioactive ingredients, and is expected to promote the innovative development of functional molecular delivery systems in the field of food.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2026
·Vol. 16
·期 3
·166
·
IF 4.3
Yunfeng Zhang,Cheng Zhao,Zhongqun Li,Dexin Kong,Lingshuai Kong
Peroxymonosulfate (PMS)-based advanced oxidation is often hindered by pH instability and the lack of post-reaction separation. Herein, commercial magnesium hydroxide (Mg(OH)2) is introduced as a multifunctional catalyst to address these limitations. Mg(OH)2effectively catalyzed PMS decomposition via a nonradical pathway dominated by singlet oxygen (1O2) generation, achieving rapid and complete degradation of electron-rich pollutants like bisphenol A (BPA) within 40 min. The system exhibits exceptional pH self-regulation, stabilizing the solution at ~9.8 and maintaining high efficiency across an initial pH range of 3–11. Mechanistic studies confirm1O2as the primary reactive species with a steady-state concentration of 1.67 × 10−12M. The catalyst demonstrates strong resistance to common anions and humic acid, along with excellent stability over four cycles. Furthermore, Mg(OH)2enables in situ flocculation and removal of degradation products. This work highlights Mg(OH)2as an efficient, stable, and multifunctional activator, offering a integrated strategy for practical wastewater treatment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2026
·
IF 5.9
Hui Li,Dadi Liu,Qianrou Fan,Yulu Li,Cheng Lv,Xinlu Wang,Yang He,Jinbing Cheng,Yebin Guan,Yumin Leng
Gold nanoclusters (AuNCs) have attracted significant interest due to their unique fluorescence properties in the environmental monitoring field. In this work, we report the first pH-dependent preparation of glutathione-protected AuNCs (Glu-AuNCs) with different fluorescent emission. The Glu-AuNCs shows the intense yellow emission from samples pH 1.0–5.5, and red emission from samples pH 11.0 to 12.5, respectively. The size of AuNCs depends on the pH of the reaction solution. The characterizations of UV–vis and photoluminescent (PL) spectra show the size of AuNCs increases with increasing samples pH value. The strongly red-emitting Glu-AuNCs were applied to detect Hg 2+ ions by fluorescence quenching. Owing to the specific Hg 2+ -Glu interactions, the fluorescent AuNCs protected by the interference biothiol, Glu, showed superior selective detection of Hg 2+ . The red-emitting Glu-AuNCs provided high sensitivity for Hg 2+ detection with widely linear range of 0–20 μM and a detection limit of 1.6 nM (0.32 ppb), which is compared with the reported data in literature. To show a potentially practical application, the developed assay method was applied to detect Hg 2+ in real samples and a certified reference material. The developed simple method for Hg 2+ detection with high selectivity and sensitivity opens a new idea for other sensor development.
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Bangfeng Fu,Ruilei Yang,Sitong Zhang,Weijie Gong,Liang Zhang,Linpin Luo,Guangjun Huang,Jianlong Wang
The development of smart packaging capable of simultaneously maintaining quality and enabling real-time freshness monitoring remains a major challenge in fresh meat preservation. This work designed a multifunctional gelatin/carboxymethyl cellulose composite film (GCAB) functionalized with hydrothermally optimized Bi 2 S 3 /BiOBr heterostructure and blueberry anthocyanins. Under NIR irradiation, the film rapidly generated temperatures exceeding 50 °C, and synergized with the inherent antioxidant capacity of anthocyanins to achieve viability reduction rates of 94.42% against Staphylococcus aureus and 96.32% against Escherichia coli . The integration of these components also improved the mechanical strength (18.8 MPa tensile strength), hydrophobicity (116.8° water contact angle), and UV-blocking capability. This film effectively extended pork shelf life to 12 days under refrigerated storage (4 °C) by suppressing microbial proliferation and lipid oxidation. Furthermore, it successfully monitored pork spoilage progression through visible color changes. This work provides a novel strategy for designing next-generation active packaging materials that integrate intelligent sensing and multi-mode antibacterial functions.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MATERIALS & DESIGN
·
2026
·
IF 8.2
Hongbao Hou,Xu Li
Introduction Esophageal cancer (EC) is the most malignant tumor posing great threat to human health. Chemotherapy, as the first-line treatment for EC, can not yield expected outcome due to chemo-resistance, low efficacy of monotherapy and off-target toxicity. Hence, it is imperative to develop one novel therapeutic strategy that can realize anti-drug resistance, tumor microenvironment response drug release, and integrated multi-modal therapy. Objectives Currently, treatment of EC faces great challenges. One pH-responsive nanoplatform, CDs-DOX-GOx@PEG (CDG@PEG), composed of copper-doped carbon dots (Cu-CDs), doxorubicin (DOX), glucose oxidase (GOx), and polyethylene glycol (PEG), was fabricated to realize better treatment of EC via multi-modal synergistic and targeted therapy. Methods Microscopy. The physicochemical properties of CDG@PEG were determined via TEM, XPS, XRD, FTIR and so on. The anti-tumor capacity was assessed with KYSE-30 cells and xenograft mice models. Moreover, the therapeutic mechanism was assessed by transcriptome, immunofluorescence and immunohistochemical analysis. Results Physiochemical characterization results showed that as designed nanoplatform was successfully fabricated and was endowed with outstanding pH-responsive and O 2 /ROS-generation capacities. In vitro , CDG@PEG exhibited excellent cell uptake and potent tumor cell-killing effect. In vivo, CDG@PEG displayed superior anti-tumor effect accompanied by good biocompatibility. Mechanistically, CDG@PEG realized the EC therapy by down-regulating drug-resistant genes (such as HIF-1α related genes), inducing mitochondria dysfunction, triggering cell apoptosis. Conclusion One multifunctional nanoplatform, CDG@PEG, was successfully prepared and it exhibited excellent in vitro and in vivo anti-tumor effect, which open new venues for developing novel therapeutic strategies for chemo-resistance cancer.
✓ 已验证
DOI
高影响因子
FOOD CONTROL
·
2026
·
IF 7
Ning Zhang,Lina Yang,Fuming Zhang,Huaying Pan,He Liu
Intelligent packaging materials offer innovative solutions for the freshness monitoring and quality maintenance of high-protein foods during their preservation and distribution. However, most existing intelligent packaging films rely on single natural pigments or synthetic indicators, which suffer from narrow color-changing ranges or safety controversies, while their biodegradability is largely overlooked. To this end, the present study prepared composite films comprising soy hull nanocellulose, polyvinyl alcohol, and pullulan, into which purple cabbage anthocyanin (PCA), curcumin (CU), and their blends at different ratios (PCA:CU = 8:2, 5:5, and 2:8 v/v) were incorporated. Results indicated that PCA and CU formed a hydrogen bond network with the film matrix via phenolic hydroxyl groups, significantly enhancing the mechanical properties of the composite films (P < 0.05). The incorporation of PCA and CU also improved thermal stability and hydrophobicity while reducing water vapor permeability. Among the formulations, PCA/CU-3 (8:2 v/v) exhibited optimal overall performance, showing the most distinct color response across pH 4–12, an antibacterial rate of 93.87% against Pseudomonas fragi , and effective delay of microbial growth and total volatile basic nitrogen (TVB-N) accumulation in dried tofu, extending its shelf life to 12 days. The film color gradually changed from deep red to deep purple during spoilage, enabling visual monitoring. Additionally, PCA/CU-3 degraded noticeably within 25 days under soil-burial conditions. Overall, this study demonstrates a novel degradable food-packaging material integrating antibacterial preservation and real-time spoilage monitoring functions.
✓ 已验证
产品关联
DOI
高影响因子
POLYMER
·
2026
·
IF 5.1
Xin Yu,Li Bo Tong,Miaomiao Li,Xiangjun Li,Yinxia Dong
Steel reinforcement in concrete is prone to corrosion in a chloride environment. The resulting structural damage is the primary factor shortening the service life. Applying acrylic coatings to steel surfaces provides excellent protection. However, resin is vulnerable to alkali hydrolysis and physical damage under the harsh conditions in reinforced concrete. To address this issue, a composite coating of poly (methyl methacrylate-co-butyl acrylate-co-tannic acid-glycidyl methacrylate)/L-lysine-modified graphene oxide (PMBT/L-GO) is successfully prepared on the reinforcing steel. The active hydroxyl groups on tannic acid-glycidyl methacrylate (TA-GMA) enable the coating to neutralize OH - . The localized reduction in pH inhibits the saponification hydrolysis reaction of the resin. The incorporation of L-lysine-modified graphene oxide (L-GO) enhances barrier performance through a labyrinth effect. Modification of L-lysine creates active sites within the coating to capture Cl - . This potentially prevents the passive film formed on the surface of the reinforcing steel from being damaged. The combination of tannic acid (TA) and L-Lysine has a synergistic effect on corrosion inhibition, enhancing the anti-corrosion performance of the coating. Moreover, multi-level reversible hydrogen-bond networks are constructed in the coating matrix to achieve self-healing of micro-damage. The PMBT/L-GO coating exhibits a corrosion current density ( i corr ) of 3.84 × 10 -9 A·cm -2 in simulated concrete pore solution (SCPS). The low-frequency impedance modulus (|Z| f=0.01 Hz ) can recover to 2.94 × 10 8 Ω·cm 2 following 24 h of room-temperature self-healing after damage. This outstanding corrosion resistance and self-healing behavior indicates that it is a promising solution for protecting concrete reinforcement against corrosion.
✓ 已验证
DOI
高影响因子
Theranostics
·
2026
·Vol. 16
·期 15
·8521
·
IF 14.9
Yipeng Pang,Fructueux Modeste Amona,Hanyuan Liu,Shuming Tang,Jianlong Lao,Xi Chen,Xiaoye Wang
Rationale Chronic diabetic wounds are complicated by multidrug-resistant (MDR) infections and a deleterious oxidative microenvironment, rendering single-target therapies ineffective. This study aimed to develop a smart, dual-metal-organic framework (MOF) nanoplatform (PCNZnCy) capable of microenvironment-responsive, coordinated antibacterial, antioxidant, and pro-regenerative therapy for infected diabetic wounds. Methods The nanoplatform PCNZnCy was constructed by integrating the natural flavonoid chrysin into a zinc-doped porphyrinic MOF (PCN-224), enabling pH- and reactive oxygen species (ROS)-triggered co-release of Zn²⁺ and chrysin. Antibacterial and anti-biofilm activity was assessed against biofilm-embedded MDR pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa (PA). Antioxidant and signaling effects were evaluated by measuring ROS scavenging, mitochondrial function, endothelial cell proliferation, and activation of Nrf2/HO-1, STAT3, and Akt pathways, with confirmation using the Nrf2 inhibitor ML385. To assess efficacy and safety in a clinically meaningful setting, we used a diabetic murine wound model infected with P. aeruginosa and a systems-level transcriptomic analysis to capture the broader tissue response. Results We found that PCNZnCy showed strong synergistic antibacterial activity against MRSA and PA. Beyond that, it scavenged excess ROS, triggered Nrf2/HO-1 signaling, modulated STAT3 and Akt signaling, preserved mitochondrial health, and spurred endothelial cell growth. In diabetic mice, wounds healed faster, with improved collagen deposition and increased formation of new blood vessels, while the compound remained safe. RNA-seq data underscored a decisive move from pro-inflammatory to pro-regenerative gene expression. Conclusions PCNZnCy adapts to the wound's specific microenvironment, enabling it to kill bacteria, reduce oxidative stress, and promote tissue regeneration. In the infected diabetic models, it worked consistently well. This makes it a strong candidate for multifactorial, complex wound pathologies, in which multiple complications overlap.
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yali Zhao,Zitong Liang,Rongyan Yang,Yuan Liao,Rong Wang,Gwo Sung Lai,Yu Liu
SVICR enables interface-confined repair of triazine-polyamine NF membranes. • Confined vapor repair densifies the active layer without increasing thickness. • Li + /Co 2+ , Li + /Ni 2+ and Li + /Mn 2+ separation factors reach 53, 40 and 55 in 2 M H₂SO₄. • The resultant NF membranes advance selective metal recovery from LIB leachates. • Membranes show less than 2% performance loss after 21 days in acid/alkali. Nanofiltration (NF) application in recovering valuable metals from spent lithium-ion batteries (LIBs) is limited by the poor acid resistance and inadequate selectivity of conventional polyamide membranes. Triazine-based polyamine networks inherently possess superior pH stability and positive surface charges favorable for multivalent cation rejection, yet their synthesis is hampered by the low reactivity of cyanuric chloride (CC), resulting in loosely cross-linked active layers with suboptimal separation performance. Here, we introduce a solid-vapor interface confined repair (SVICR) strategy that transforms a preformed loose triazine-polyamine network into a dense, defect-free separation layer through spatially confined post-repair with diethylenetriamine vapor. This interface-limiting process efficiently consumes residual chlorine sites while minimizing thickness increase and hydraulic resistance. The resulting membranes exhibit exceptional mono−/multivalent ion selectivity in 2 M H₂SO₄, with separation factors of 53, 40, and 55 for Li + /Co 2+ , Li + /Ni 2+ , and Li + /Mn 2+ , respectively, alongside a water permeance of 4–8 L·m −2 ·h −1 ·bar −1 . Moreover, the membranes demonstrate outstanding long-term stability under extreme conditions, sustaining less than 2% performance decline after 21 days of exposure to 2 M H₂SO₄, 2 M HCl, or 1 M NaOH. The SVICR strategy establishes a processable and effective platform for fabricating pH-resistant NF membranes, advancing sustainable LIB recycling technologies. Download: Download high-res image (122KB) Download: Download full-size image
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Yuandong Lin,Chunfeng Zhang,Jiangbo Li,Xiaobo Zou,Zuohan Zhang,Shaolin Deng,Di Zhao,Jun-Hu Cheng
Dual-ligand engineering significantly enhances QYs of DPA-KA-CuNCs. • PL improved via size confinement, surface passivation, and enhanced LMCT. • A pH-responsive “turn-on” fluorescence enables highly sensitive VBNs detection. • Paper-based fluorescent label allows rapid and visual colorimetric sensing. • Real-time shrimp freshness monitoring with strong TVB-N correlation (R 2 = 0.98). With increasing consumer demand for food safety, conventional freshness detection methods remain limited by subjectivity and operational complexity. Herein, highly emissive green fluorescent copper nanoclusters (CuNCs) were developed as intelligent packaging labels via dual-ligand engineering of kojic acid (KA)-stabilized CuNCs with D-penicillamine (DPA). DPA markedly improved the fluorescence quantum yield from 1.2% to 11.4% by promoting ultrasmall cluster formation (∼2 nm), enhancing quantum confinement, and passivating surface defects. The obtained DPA-KA-CuNCs exhibited a pH-responsive fluorescence “turn-on” behaviour toward volatile basic nitrogen compounds (VBNs). Fluorescence quenched under acidic conditions was efficiently restored upon exposure to ammonia, dimethylamine, and trimethylamine through ligand deprotonation and enhanced ligand-to-metal charge transfer. Detection limits reached 0.23, 0.19, and 0.18 ppm, respectively. A paper-based fluorescent label further enabled visual monitoring of shrimp freshness, showing excellent correlation with TVB-N values (R 2 = 0.9835). This work provides a sensitive and visual strategy for non-destructive aquatic product freshness evaluation. Download: Download high-res image (187KB) Download: Download full-size image
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）