JOURNAL OF NANOBIOTECHNOLOGY
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2026
·Vol. 24
·期 1
·307
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IF 15
Meng Can,Nan Weijin,Wu Meiliang,Guo Qingyu,Zhang Wenxin,Wu Hong,Zhang Yan
GelMA-OHA/ZIF8@BMP4 (GOZB) was developed from oxidized hyaluronic acid and GelMA, incorporating BMP4-loaded ZIF8 nanoparticles for sustained release.
GOZB restores corneal epithelial ultrastructure and barrier integrity, promoting tissue repair in corneal injury models.
GOZB effectively suppresses inflammation, oxidative stress, and neovascularization, showing excellent therapeutic efficacy and safety for CoNV.
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APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
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2026
·Vol. 132
·期 5
·459
·
IF 3
Cong Xinyue,Jiang Yi,Gu Hao,Zhang Limei,Wang Jiaming,Song Xiqing,Yuan Yishan,Shan Mingzhe,Liu Zhanqi,Shen Mengyang
With the continuous advancement of Internet of Things(IoT) technology, flexible pressure sensors have been extensively researched as core components of wearable devices. However, achieving high sensitivity without compromising stability remains a challenge for most sensors. Inspired by volcanic stone, this paper reports a three-dimensional porous microstructural design termed "volcanic stone" and successfully fabricates a flexible porous piezoresistive sensor based on MWCNTs/PDMS using sugar cubes as a sacrificial template.The multi-layered structure formed by this method exhibits a large pore architecture on the scale of hundreds of micrometers. It features a hollow framework ranging from sub-micrometer to micrometer dimensions. Irregular pores are distributed across the skeleton, adding structural complexity at the microscale. The arrangement of this structure is conducive to establishing a highly interconnected conductive network. The sensor can be used to monitor body motion and some subtle vital signs. Here, we demonstrate a flexible pressure sensor that has excellent stability and outstanding durability. Notably, it maintains a 95% cycle retention rate after 8,750 cycles and achieves ultrahigh sensitivity (up to 395.53 kPa⁻ 1 at 0–9 kPa and 979.39 kPa⁻ 1 at 9–14 kPa). The response and unloading times were both 200 ms. And it had excellent bending and torsion properties, with an elastic deformation of 400%. It significantly improves the monitoring performance and has broad application prospects in healthcare, human–computer interaction, and other fields.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2026
·Vol. 37
·期 12
·902
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IF 3.2
Zhong Huaiyu,Zhu Zhanglin,Cai Haoqi,Ruan Dianxu,Li Zhimei,Zhong Qingdong,Huang Lei
In this paper, a copper wire beam electrode (WBE) was used to monitor the formation and cracking behavior of the solid electrolyte interface (SEI) film on the surface of FeSi alloy anode materials. The corrosion products were analyzed via scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The results showed that the corrosion pattern of FeSi alloy in electrolyte solution changes from local corrosion to uniform corrosion, which indicates the gradual formation of the SEI film on the FeSi alloy surface. When a column of FeSi alloy was removed in situ, corrosion behavior was divided into three stages. In the initial stage, local corrosion was observed with the FeSi alloy acting as the anode. In the middle stage, the exposed Cu electrode acted as the anode for local corrosion. In the later stage, cracking of the SEI film and further propagation of cracks on the surface of FeSi alloy lead to uniform corrosion of the Cu WBE. This phenomenon showed that the formation of corrosion products and the accumulation of fluorine ions on the Cu WBE are the reasons for the rupture of SEI film and the formation of micro − cracks on the surface of FeSi alloy.
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Light-Science & Applications
·
2026
·Vol. 15
·期 1
·210
·
IF 24
Zhang Xiang,Wu Yuanwu,Ou Jianfeng,Shen Zixi,Liu Nian,Alshahrani Thamraa,Mohd Yusoff Abd. Rashid bin,Tang Jiang,Luo Jiajun
Purity has been fundamental to the fabrication of high-performance semiconductors, spanning from precursors to reaction atmospheres. Emerging thermally evaporated perovskites involving precise control impose even stricter requirements on the purity of the vapor atmosphere. Compared to the purified solvent for the reaction atmosphere in the solution-based method, efficient and effective vapor purification remains unexplored. Here, we report one-step vapor purification for a pure atmosphere with less than one percent detrimental impurity. The in-situ residual gas analysis was employed to emphasize the complexity of the gas-phase composition and reveal the impurity reaction competition during the purification. The pre-control of the vapor atmosphere enabled a record external quantum efficiency over 20% for a thermally-evaporated perovskite light-emitting diode (PeLED) based on defect-suppressed FA x Cs 1- x PbBr 3 films. Moreover, the PeLED display panels exhibit over 5-fold and 2-fold magnification in operational and storage stability. The stability extension in OLEDs by this strategy demonstrates its universal effectiveness and commercialization potential for other types of thermally evaporated optoelectronic devices.
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Nature Communications
·
2026
·
IF 18.1
Fu Yubing,Chen Xinyu,Lu Liwei,Yang Wenwei,Gan Siyu,Yan Xueling,Liu Lan
Developing sustainable adhesives with simultaneous high adhesive strength and excellent work of debonding remains challenging. Here, strong, ultra-tough, environmentally reliable, and recyclable polyurethane adhesives are reported, utilizing a multiscale engineering approach. The multiscale structure employs a top-down design philosophy to merge the advantages of both thermoplastic and thermosetting systems, integrating multi-level organizations including macroscale dual-length dynamic crosslinked networks, mesoscale initial and fibrillar crystals, nanoscale hard phase domains, and molecular scale weak hydrogen bonds. The multiscale structure exhibits the following features: multi-level organizations and surface-anchored high energy phases significantly enhance the bulk cohesion and interfacial adhesion, respectively. And hydrophobic organizations provide barrier mechanisms, while dynamic crosslinking enables network reconfiguration. As a result, the developed adhesive exhibits both high adhesive strength (21.24 MPa) and ultrahigh work of debonding (35,731 N m -1 ), coupled with excellent physical and chemical recyclability and environmental reliability (high humidity, water, organic solvents, acids and alkalis, high and ultralow temperatures, aging). This work highlights how multiscale structure enabled by dual-length crosslinked networks simultaneously optimizes bulk cohesion and interfacial adhesion, offering a perspective for designing strong and tough adhesives.
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European Journal of Wood and Wood Products
·
2026
·Vol. 84
·期 3
·65
·
IF 2.7
You Ziyuan,Yu Yang,He Zengcheng,Qiu Zhe,Xiao Zefang,Yu Fanjun,Zhang Tianpeng,Xie Yanjun
Titanium dioxide has been used as an efficient UV-reflecting agent in wood photodegradation resistance treatment due to its UV shielding effect, but the influence of its photocatalytic performance on the aging behavior of wood was still neglected. The objective of the present study was to investigate the potential and mechanism of anatase and rutile titanium dioxide (A-TiO 2 and R-TiO 2 ) in enhancing the weathering resistance of poplar. The weathering resistance of untreated poplar veneer (P), anatase titanium dioxide-modified poplar veneer (AP) and rutile titanium dioxide-modified poplar veneer (RP) was systematically evaluated by using accelerated weathering test methods. AP and RP exhibited excellent dimensional retention and color stability under UV radiation, relying on their UV shielding. However, it is interesting to note that RP still showed a relative weathering advantage under the simultaneous presence of UV & water weathering, while AP exhibited a paradoxical accelerated aging phenomenon. The A-TiO 2 was proven to accelerate the degradation of lignin, resulting in destruction of the β-O-4-Linked structures characterized by 2D-NMR, which can be attributed to its photocatalytic properties.
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Nature Communications
·
2026
·
IF 18.1
Huang Nuanshan,Fang Jun,Wang Xin,Hu Sixia,Li Sibo,Xie Guanshui,Gan Lin,Peng Haichen,Lin Xiao,Zhang Xiaoshan,Liu Fengde,Yang Ziqing,Zhao Peng,Huang Pengfei,Li Wenjia,Qiu Longbin
Wide-bandgap (WBG) perovskite solar cells (PSCs) have emerged as promising candidates for tandem applications, despite potential instability induced by halogen components. Formamidinium-cesium (FACs)-based perovskites represent as an intrinsically stable WBG system due to their low bromine-to-lead ratio and the absence of thermally unstable methylammonium. However, the performance of FACs-based WBG perovskites is highly dependent on achieving precise control over the formation dynamics. Here, we employ in-situ characterization to reveal that the key to this control lies in the evolution of the intermediate phase and propose a pathway-priming strategy. By strategically guiding the early formation of the CsPbX 3 intermediate phases, the strategy in turn templates and accelerates the subsequent transformation to the desired α-phase. The primed pathway yields a more uniform and complete phase transition, leading to enhanced film homogeneity. As a result, we demonstrate highly efficient 1.67 eV WBG PSCs with an efficiency exceeding 23%, along with excellent long-term operating stability maintaining 90% initial performance for 800 hours under continuous light stress. Furthermore, semitransparent WBG PSC achieve efficiencies of 20.91% (0.1 cm 2 ) and 19.67% (1.0 cm 2 ), corresponding to a four-terminal perovskite/silicon tandem solar cells with an efficiency of 31.04% (1.0 cm 2 ), highlighting their potential for high-performance tandem photovoltaics.
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Nature Communications
·
2026
·
IF 18.1
Zhao Zhenyu,Liao Jing,Wang Long,Sun Jijun,Xie Yujie,Chen Yu,Chen Chang
Tracheal defects constitute severe respiratory disorders arising from multifactorial etiologies, with current therapeutic modalities significantly constrained by anatomical limitations, compromised vascularization at anastomotic sites, and frequent graft rejection. These challenges are further compounded by the inability to deliver continuous and quantitatively controlled regenerative signals, thereby limiting the efficacy of tissue regeneration and vascular reconstruction. Herein, we designed a mechanically driven, 3D-printed piezoelectric system (PFT) capable of transducing mechanical energy into therapeutic cues upon exogenous ultrasound activation. By leveraging the synergistic interplay between ultrasound-induced micro-expansion of the patch for effective defect occlusion and the simultaneous electromechanical transduction of regenerative signals, this system enables coordinated enhancement of both structural sealing and vascular reconstruction, thereby facilitating efficient and integrated tracheal defect repair. As a sustainable external modulation method, the mechanically-driven expandable patch system can serve as a broadly applicable strategy to enhance regenerative therapy for various systemic organs dependent on vascularization.
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METABOLIC BRAIN DISEASE
·
2026
·Vol. 41
·期 1
·153
·
IF 3.8
Li Chunlei,Li Yuan,Liu Tongyan,Zong Yue,Zhou Lingyun
Spinal cord injury (SCI) is a highly disabling condition affecting the central nervous system (CNS). Neuroinflammation and neuronal apoptosis are two critical factors in the pathological process of SCI. Although electroacupuncture (EA) has been reported to alleviate neuroinflammation in brain injury, the underlying molecular mechanism remains unclear. Transcriptome sequencing of spinal cord tissues was performed to identify potential key factors and pathways involved in EA post-SCI. DHCR24, a cholesterol synthesis regulator, was selected as a key candidate and DHCR24 was downregulated after SCI (log 2 FC = -1.6, P < 0.01), and this downregulation was notably reversed by EA treatment (log 2 FC = 1.04, P < 0.01). We investigated the neuroprotective effect of DHCR24 against neuron death and neuroinflammation in SCI, with a particular focus on its effects on the Wnt signaling pathway. SCI-induced DHCR24 downregulation was associated with decreased expression of the axonal regeneration marker NF and increased activation of Iba1/CCR7-positive microglia, accompanied by enhanced neuronal apoptosis and inflammatory factor release. Importantly, functional validation experiments demonstrated that DHCR24 was required for the therapeutic effects of EA. Complementary in vitro studies in LPS/IFN-γ-stimulated BV2 microglia cells confirmed the role of DHCR24 in microglial polarization and neuronal survival, likely via Wnt signaling activation. Integrating transcriptomic and mechanistic evidence, we demonstrate that DHCR2 promotes Wnt pathway activation, reduces neuronal apoptosis and neuroinflammation, and ultimately enhances spinal cord repair. This study provides evidence supporting the potential clinical application of EA in SCI recovery and identifies DHCR24 may be a key mechanistic target underlying its therapeutic effects. Graphical
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Science China-Life Sciences
·
2026
·Vol. 69
·期 7
·2360-2375
·
IF 9.6
Wang Tianxiao,Shao Weihua,Zhou Ting,Li Yuchao,Qin Ran,Chen Ziyu,Cao Jikang,Hu Xinyu,Cang Jingxuan,Sun Chang,Wang Yuli,Jiang Huijun,Han Feng,Pan Yongchu,Yuan Hua,Jiang Jiandong,Wu Fan
Radiotherapy-induced osteoradionecrosis of the jaw (ORNJ) affects quality of life by causing severe pain, persistent infections, and stomatognathic dysfunction. Current ORNJ treatments are limited by several factors, including surgical trauma and notable individual differences. Oxidative stress, which is a critical driver of radiation-induced injury, promotes inflammation and disrupts the balance between bone formation and resorption. Here, we developed ceria-doped silicate nanozymes (CeSNs) to eliminate reactive oxygen species (ROS) by inducing a superoxide dismutase-like (SOD-like) and catalase-like (CAT-like) cascade. ROS-eliminating mitophagy contributed to the restoration of jawbone radiation injury. Dl-3-n-butylphthalide (NBP) encapsulated in CeSNs (NBP@CeSNs) demonstrated improved pH-responsive release for enhanced angiogenesis, while the silicon ions of silicate enhanced jawbone osteogenesis, thus providing the nanozymes with angiogenesis and osteogenesis capabilities. Our NBP@CeSNs nanozymes provided a promising pathway for ORNJ treatment.
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JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
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2026
·
IF 2.6
Xu Xiaobin,Gao Qiang,Ma Yue,Dong Chengwei,Ye Bing,Zhou Fei
M142 aluminum alloy, commonly used in piston systems, exhibits inadequate performance under prolonged high-temperature and high-load conditions. This study developed a TiO 2 nanoparticle-reinforced Ni-Fe composite coating via electrodeposition to address this. The effect of FeSO 4 ·7H 2 O concentration on Ni-Fe coatings was first investigated. The results show that hardness increased with FeSO 4 ·7H 2 O concentration, while the wear rate initially decreased and then increased. Adding TiO 2 nanoparticles effectively mitigated the adverse effects of high Fe content, leading to a dense, homogeneous composite structure (NFT15). Compared to the NF25 coating, the TiO 2 -reinforced coating demonstrated a 19.5% increase in hardness, a 30% improvement in adhesion strength, and a 30.9% decrease in wear rate. It also exhibited superior thermal stability, maintaining structural integrity and showing a 41.7% hardness increase after thermal cycling. Finally, a multi-performance evaluation identified the composite coating with 15 g L −1 TiO 2 as possessing the optimal overall properties.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 7
·489
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IF 5.4
Zhao Jingyu,Sun Haiyue,Li Yunlun,Liu Hongyan,Zhang Haijun,Xin Junhong
The efficient enrichment and simultaneous detection of trace levels of angiotensin (Ⅰ, Ⅱ, Ⅲ) and aldosterone in plasma pose certain technical challenges. Herein, we propose a novel strategy where a cationic covalent organic framework (Py-BPy 2+ -COF) was served as an attractive adsorption material for efficient enrichment of angiotensin (Ⅰ, Ⅱ, Ⅲ) and aldosterone. Adsorption experiments and model fitting revealed that Py-BPy 2+ -COF exhibited adsorption capacities ranging from 5.02 to 26.12 μg g −1 for the four target analytes. The Hirshfeld partition analysis elucidated that the interaction forces of angiotensin and aldosterone with Py-BPy 2+ -COF originated from electrostatic interactions, π-π stacking and hydrophobic interactions. Py-BPy 2+ -COF was employed as the sorbent packing in a 96-well plate coupled with liquid chromatography-tandem mass spectrometry, achieving high sensitivity, excellent reproducibility, high recoveries (80.1%-94.9%), low limits of detection (5–50 pg mL −1 ), and cost-effectiveness, while maintaining high extraction efficiency even after 10 repeated uses. This study provides a novel approach for the detection of angiotensin (Ⅰ, Ⅱ, Ⅲ) and aldosterone in plasma, and demonstrates the potential of cationic COFs as functional materials in biomedical analysis. Graphical
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