Nature Communications
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2026
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IF 18.1
Zhou Xuanzheng,Xu Kang,Li Zekai,Dong Yuxuan,Chao Jinghui,Zhai Yufei,Jin Ying,Xu Shaolin,Wang Min
Fluorescence-based thermometry offers non-contact, high-resolution temperature sensing, yet current methods face challenges in simultaneously achieving high sensitivity, stability and insensitivity to non-thermal perturbations. Here, a sensing paradigm is introduced that translates temperature variations into detectable shifts in the fluorescence emission angle via grating-modulated fluorescence emission. In a prototype device featuring a gold grating coupled with [Ru(phen)₃]Cl₂ fluorophores, an absolute sensitivity of 0.58 °/°C and a relative sensitivity of 81.34 %/°C at 79.36 °C are achieved, with a temperature resolution down to 0.01 °C. Unlike intensity-based methods, this angle-resolved strategy effectively isolates the thermal signal from excitation power fluctuations and environmental interferences and demonstrates robustness across broad humidity ranges (10–89% RH). Sustained operational stability is validated over 12-hour battery cycling, while real-time monitoring of a smartphone CPU enables early-warning capabilities against overheating. This promising and customizable approach establishes a pathway for thermal management in advanced engineering systems.
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CELLULOSE
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2026
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IF 4.6
Ye Xuan,Wang Xin,Chen Siying,Ma Yunyan,Yao Shuangquan,Qin Chengrong,Li Wei,Liang Chen
Bamboo exhibits fiber lengths comparable to those of softwood species, making it a high-quality raw material for long fibers. However, the effective separation and utilization of these long fibers are severely impeded by the parenchyma tissue present in bamboo. Therefore, the efficient separation of vascular bundles and parenchyma tissue from bamboo is a crucial prerequisite for achieving high-value utilization of its long fibers. This study systematically evaluates and quantifies the impact of alkaline conditions on the selective separation of bamboo vascular bundles (VB) and parenchyma cells (PC) through single-factor experiments, reveals the microscopic mechanisms that induce selective removal of PC, and proposes a mild pretreatment method that balances yield while preserving fiber integrity. The VB and PC samples obtained at different treatment temperatures were thoroughly characterized in terms of microstructure, chemical composition, crystallinity, and thermal stability. The results indicated that alkali treatment removed lignin from the cell corner middle lamella and compound middle lamella of bamboo, facilitating the separation of VB and PC. When PC separation efficiency reached its maximum (10.28%), VB separation efficiency was 65.64%. Under these conditions, the crystallinity index, and cellulose content of the samples were significantly increased. PC was found to have a higher syringyl/guaiacyl (S/G) ratio and a lower content of condensed lignin linkages, indicating greater reactivity under alkaline conditions. This study elucidates the mechanistic differences in alkali-induced separation of two tissue types for the first time, providing empirical data and a theoretical foundation for optimizing the efficient separation process of VB and PC.
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Nature Communications
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2026
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IF 18.1
Zhao Shufang,Wang Maolin,Chen Xiangxiang,He Huiwen,Xia Zhuohao,Wang Meng,Wu Xiaojie,Zhou Xian,Xu Wenqing,Liu Yakun,Ran Qidi,Xu Yao,Xu Binjun,Li Xiao-nian,Yao Siyu,Lin Lili,Ma Ding
Cyclohexanones, as critical precursors for polyamide 6, are inherently challenging to synthesize from lignin-derived phenolic bio-oils due to the high dissociation energy of the aryl-OCH 3 bond and the competitive risk of C=O bond over-hydrogenation. To address this intrinsic selectivity trade-off, we report the selective synthesis of cyclohexanones from lignin-derived phenolic monomers via a H 2 -free photothermal catalytic process using a RuPd/TiO 2 photocatalyst at 150 °C, with a selectivity of 94% and an activity of 12 mol -one ∙mol Ru+Pd −1 ∙h −1 . Through the proton-coupled electron transfer process, photogenerated electrons drive precise aryl-OCH 3 cleavage, and the resulting methoxy groups and water are utilized as internal hydrogen source. The low pressure of H* generated in situ is key to maintaining the high selectivity. The alkyl-substituted ketone is subsequently converted into the corresponding caprolactam monomer and copolymerized with conventional caprolactam. The propyl-functionalized polyamide 6 exhibits enhanced properties, including 88.9% transparency and 523% elongation at break, whereas conventional polyamide 6 (no alkyl) has only 71.5% transparency and 120% elongation, respectively. This work not only establishes a robust and chemically precise photothermal platform for selectively converting lignin to cyclohexanones, but also demonstrates that alkyl functionalization unlocks unprecedented properties in polyamide 6, thereby greatly increasing its value.
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Nature Communications
·
2026
·
IF 18.1
Zeng Yicheng,Liu Xiaonan,Liu Duanyang,Liu Yuan,Wang Qingya,Chen Weiwei,Wei Jing,Xu Jian,Liu Fangze,Li Hongbo
Colloidal quantum nanorods (NRs) exhibit linearly polarized emission and fast radiative recombination owing to their two-dimensional confinement, enabling high-performance light-emitting diodes (LEDs). However, due to facet-dependent growth kinetics, anisotropic shell growth often leads to preferential overgrowth along the long axis and insufficient radial (short axis) coverage. This structural imbalance weakens exciton confinement within the core and compromises the suppression of Förster resonance energy transfer. Here, we report a dual-ligand (organic phosphorus/carboxylic acids) slow-injection strategy to synthesize wurtzite CdSe/CdZnSe/ZnSeS core/shell NRs featuring compositionally graded thick shell ( ≈ 4.5 nm) with ZnSe as the dominant component. The organic phosphorus ligands create an environment of high monomer concentration (cadmium monomer concentration from 1.4% to 2% of cadmium by mass) to drive anisotropic growth, while the carboxylic acids promote isotropic growth due to their nearly equal binding energy across different crystal facets. Simultaneously epitaxial growth of compositionally graded alloy shells alleviates lattice mismatch at core/shell interfaces while reducing defect density and boosting carrier recombination efficiency. The resulting NR-LEDs achieve an external quantum efficiency of 32% for anisotropic nanocrystals. This work establishes graded thick-shell NRs as a generalizable platform for efficient, stable and polarized optoelectronics.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2026
·Vol. 37
·期 16
·1229
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IF 3.2
Xu Bing,Zhang Jian,Zeng Fanen,Pang Jiaxi,Yang Qinyi,Wu Xin,Sun Zhidong,Yu Hongbo
Biomass-derived porous carbons are considered promising supercapacitor electrodes owing to their sustainable precursors, cost-effectiveness, and superior structural features. Using bamboo shoot shells (BSSs) as the precursor, BSS-derived porous carbon was synthesized through a NaOH-assisted hydrothermal process and subsequent activation in air. The impact of hydrothermal temperature and duration on the material’s physicochemical characteristics and subsequent supercapacitor performance is methodically examined in this work. The as-prepared sample (BSSN-160–10) delivers a high specific capacitance of 211.4 F·g −1 at a current density of 1 A·g −1 , demonstrating exceptional electrochemical performance. Retaining 101% of its capacitance over 30,000 cycles, the symmetric supercapacitor yields an energy density of 15.15 Wh·kg −1 at a power density of 500 W·kg −1 . High energy density, high power density, and exceptional cycling longevity are all achieved by BSS-derived porous carbon in supercapacitor electrodes. Thus these materials offer a compelling candidate solution for green energy storage.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2026
·Vol. 37
·期 14
·1088
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IF 3.2
Liu Yong,Ke Binqing,Zhang Keju,Wu Longhua,Xia Qing
The environmental pollution caused by phenolic pollutants has attracted more and more attention, and developing simple and efficient detection methods for phenolic pollutants has aroused great interest of researchers. In this paper, a reduced graphene oxide (RGO)-modified electrode with high electrocatalytic activity was prepared by simple electrochemical reduction of graphene oxide (GO) on a glassy carbon electrode using cyclic voltammetry. The electrode-modified materials were systematically characterized by UltraViolet–Visible (UV–Vis), Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FE-SEM), X-ray diffraction spectroscopy (XRD) and electrochemical impedance spectroscopy (EIS). Differential pulse voltammetry (DPV) was employed to detect catechol with high sensitivity. The effects of conditions such as the amount of GO suspension, cycle number of cyclic voltammetry reduction, pH value of the buffer solution, and accumulation time on the detection of catechol were investigated. Under optimal conditions, the oxidation peak current of catechol showed a good linear relationship with its concentration when the concentration of catechol was in the range of 1 × 10 −7 M ~ 1 × 10 −5 M. The linear equation was expressed as I (μA) = 2.1321 C (μM) + 4.2807 with a correlation coefficient of 0.9902, and the limit of detection (LOD) was 4.5 × 10 −8 M. Meanwhile, this electrochemical sensor has been proven to be applicable for the determination of catechol in an actual water sample.
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Natural Products and Bioprospecting
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2026
·Vol. 16
·期 1
·68
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IF 5.8
Yang Jing,Kang Chongxin,Xiao Chulei,Zhang Yusi,Mai Yihong,Huang Yinghong,Zhan Yi,Liu Hetong,Wang Xian
Naringin and phloridzin are structurally similar flavonoids with anti-inflammatory, antioxidant, and antimicrobial properties, showing considerable potential as natural therapeutic agents. This study demonstrated that naringin and phloridzin exert anti-inflammatory effects and preserve normal intestinal function in UC mice. This protective effect is mediated by inhibition of the NF-κB signalling pathway. To investigate metabolic differences, we employed UPLC-MS/MS-based widely targeted metabolomics alongside targeted analyses of tryptophan (Trp) and short-chain fatty acids (SCFAs). Comparative analysis of metabolic profiles, differential metabolites, and associated pathways revealed regulatory effects on Trp and SCFAs. However, naringin demonstrated superior regulation of Trp metabolism and SCFA levels compared to phloridzin, resulting in more pronounced improvement of gut homeostasis. These findings elucidate the metabolic mechanisms underlying both flavonoid treatments and underscore their potential as complementary therapies for UC. Graphical abstract Naringin and phloridzin exert protective effects against DSS-induced ulcerative colitis by modulating tryptophan metabolism and suppressing inflammation through inhibition of the NF-κB signaling pathway
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Science China-Materials
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2026
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IF 7.7
Zhu Jinliang,Sun Xiaohan,Zhou Jiazuo,Liu Yifan,Ji Xinyao,Wang Fangmiao,Li Congteng,Tian Xue,Dong Xin,Ba Shuaijie,Yang Haiyue,Wang Chengyu
Stimuli-responsive fluorescent hydrogels, owing to their tunable optical property and unique smart response characteristics, have significant potential in encryption applications and information security. However, most current systems are limited to single-stimulus responsiveness and lack the capability for programmable information erasure or multi-modal dynamic synergy. Hence, we propose a multi-stimuli-responsive phase-change hydrogel incorporating aggregation-induced emission hydrophobic carbon dots (AIE-HCDs) and polyethylene glycol (PEG)-cellulose network, demonstrating dynamic fluorescence chromism under various external triggers. The hydrogel exhibits solvent-exchange-triggered fluorescence color changes from blue to red, enabled by the concentration modulation of AIE-HCDs through the exchange between PEG and water. Additionally, the temperature-induced phase transition of PEG from crystalline to molten state modulates the aggregation and dispersion of AIE-HCDs, thereby enabling dynamic fluorescence color changes. The phase transition further confers excellent shape-memory behavior and adjustable mechanical properties, with the tensile modulus varying from 6.28 MPa in the molten state to 36.23 MPa in the crystalline state, while maintaining high transparency (∼8% in the molten state). By utilizing microcontact printing and the multi-stimulus response, an encryption platform enables information to be hidden, selectively read under sequential stimuli (thermal, UV, and solvent), and completely erased upon demand. This strategy demonstrates significant potential for advancing high-level information encryption and anti-counterfeiting technologies. The alternative text for this image may have been generated using AI.
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JOURNAL OF NANOBIOTECHNOLOGY
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2026
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IF 15
Zhang Yiling,Li Yu,Lu Jiayu,Qin Xin,Wang Zixin,Cai Aojie,Fan Ling,Jin Ronghua,Xie Yandong
To address the therapeutic limitations and metabolic toxicity associated with conventional nanocarriers, a nanostructure using an “MOF-in-MOF” strategy was engineered. The comprises an olsalazine (Olsa)-based copper metal-organic framework (Olsa-MOF) that integrates intrinsic anti-inflammatory properties and enhanced chemodynamic performance. This Olsa-MOF template is integrally enveloped by a tumor microenvironment-responsive TK-based Cu-MOF layer, which demonstrates exceptional photothermal properties. Subsequent surface functionalization with dopamine-grafted hyaluronic acid (DOPA-HA) endows active targeting ability, yielding the final nanocomposite termed Olsa@TK-Cu@HA. Olsa@TK-Cu@HA not only overcomes the limitations of conventional nanocarriers but also offers a novel strategy to enhance the therapeutic efficacy of photothermal therapy (PTT) and chemodynamic therapy (CDT) through targeted modulation of the COX-2/PGE2 inflammatory axis. The Olsa@TK-Cu@HA demonstrates a superior photothermal conversion efficiency (26.8%) and robust reactive oxygen species (ROS) generation, along with pH-responsive release of Olsa. In vitro evaluation demonstrated that Olsa@TK-Cu@HA exerts tumor-selective cytotoxicity, showing 3.5-fold higher potency against cancer cell. Moreover, Olsa@TK-Cu@HA effectively induces immunogenic cell death (ICD), as evidenced by increased extracellular ATP efflux (5.06-fold elevation) and CRT exposure. Concurrently, it downregulates the COX‑2/PGE2 axis to relieve immunosuppression in the tumor microenvironment and suppresses PD‑L1 expression. This coordinated action amplifies ICD‑mediated antitumor immunity, leading to a tumor regression rate of 84.0% in vivo. By integrating precision targeting, stimulus-responsive drug release, and immunometabolic reprogramming, this work moves beyond conventional treatment paradigms and establishes an innovative platform for next‑generation cancer therapy. Graphical The alternative text for this image may have been generated using AI.
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Journal of Natural Medicines
·
2026
·
IF 2.6
Mao Qiang,Zhong Huan,Liang Wan-Li,Dai Jin,Huang Rui-Ting,Wang Yi-Di,Sun Di-Yang,Tang Kai,Xia Long-Fei,Gong Hai-Biao,Li Yi-Fang,Sun Wan-Yang,Zhang Qiong-Yi,Zeng Li,Yu Li-Li,Xu You-Hua,Wu Qi-Biao,Zhu Yi-Zhun,Tan Hong-Li,Ouyang Shu-Hua,He Rong-Rong
Natural Calculus Bovis (NCB) and Bovis Calculus Sativus (BCS) are both used clinically but exhibit different therapeutic effects, the material basis of which remains unclear. Lipid-soluble components are hypothesized to contribute to these differences, however the compositional variations at the lipid level have not been fully characterized. In this study, untargeted UHPLC-MS/MS lipidomics was employed to compare the lipid profiles of NCB and BCS. The results indicated that both samples contained fatty acyls, glycerolipids (GL), glycerophospholipids (GP), sphingolipids (SP), and sterol lipids (ST), indicating a conserved core lipid framework. However, NCB showed higher lipid complexity and abundance. NCB contained higher levels and greater molecular diversity of intact GP (phosphatidylcholines and phosphatidylethanolamines), SP (ceramides), fatty acid-derived lipids (polyunsaturated N -acylethanolamines, PU-NAE), and sterol esters. In comparison, BCS exhibited a simplified profile dominated by GL, with reduced GP, SP and ST species, enrichment of lysophospholipids and bile acid-related sterols, and lower overall lipid abundance. These differences may result from distinct formation processes: prolonged in vivo maturation for NCB versus time-limited in vitro culturing for BCS. This study expands the current understanding of the material basis of NCB and BCS, from a lipidomic perspective, offering molecular insights into its pharmacological properties and providing a scientific foundation for the material basis, quality control, standardization and rational clinical application of Calculus Bovis . Graphical abstract The alternative text for this image may have been generated using AI.
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Food Analytical Methods
·
2026
·Vol. 19
·期 8
·238
·
IF 3
Li Jinyu,Cui Jinqi,Li Shunmei,Zhang Zhuorui,Jiang Guiquan
Single-factor experiments and response surface methodology were employed to optimize the extraction of anthocyanins from the fruits of Amelanchier alnifolia (Saskatoon berry) using deep eutectic solvents (DES). The extracted anthocyanins were characterized using Fourier-transform infrared spectroscopy (FTIR) and ultra-performance liquid chromatography–mass spectrometry (UPLC–MS). Optimal conditions were as follows: choline chloride:acetic acid (1:3 molar ratio, DES-3); water content, 60% (v/v); solid-to-liquid ratio, 1:20 (g/mL); extraction time, 50 min; extraction temperature, 30 °C. Under these conditions, the extraction yield reached 4.84 ± 0.18 mg/g, which was 1.88-fold higher than that obtained using ethanol, and the purity of the extracted anthocyanins was 9.28 ± 0.56%, representing a 1.44-fold increase compared with ethanol extraction. The DES-extracted anthocyanins were identified as anthocyanin glycosides, primarily cyanidin-3-O-glucoside, cyanidin-3-O-α-arabinose, delphinidin-3-O-galactoside, delphinidin-3-O-glucoside, and delphinidin-3-O-α-arabinopyranoside. The bioactivity of the extracts was evaluated using in vitro antioxidant assays and hypoglycemic tests. DES-3-extracted anthocyanins had IC 50 values of 54.56, 56.86, and 46.67 μg/mL for scavenging hydroxyl radicals, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, and superoxide anions, respectively. On average, the antioxidant activity of DES-3-extracted anthocyanins was approximately 1.12-fold higher than that of ethanol-extracted anthocyanins. DES-3-extracted anthocyanins concentration-dependently inhibited both α-amylase and α-glucosidase, with IC 50 values of 26.78 and 22.95 μg/mL, respectively; these values are approximately 1.17-fold lower than the equivalent values for ethanol-extracted anthocyanins. DES-3 appears to be an efficient, green solvent for Saskatoon berry anthocyanins, yielding extracts with enhanced in vitro antioxidant and hypoglycemic activities. Graphical
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2026
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IF 4.1
Liu Weiyi,Wang Xin,Cong Lili,Xu Shuping
Matrix metalloproteinase-9 (MMP-9) plays a crucial role in cancer cell invasion, metastasis, and tumor growth. However, the precise and sensitive detection of MMP-9 remains a significant challenge, impeding a deeper understanding of its multifaceted roles in cancer progression. This study developed a novel surface-enhanced Raman scattering (SERS) sensing strategy based on DNA bending for ultrasensitive, highly selective detection of MMP-9. In the sensing system, MMP-9 aptamers and methylene blue–labeled complementary DNA were co-modified on a magnetic/plasmonic bead to fabricate a SERS probe. When target MMP-9 was present, the aptamer bound to the target and detached from the SERS nanoprobe, and the complementary DNA chain modified with methylene blue, due to its bending and the resultant closer proximity to the SERS nanoprobe surface, led to enhanced SERS signals. Meanwhile, cell experiments have confirmed that intensified hypoxia can directly lead to a significant increase in MMP-9 expression. Due to the high affinity between the aptamer and the target, this sensing system has high selectivity. The detection limit arrives at 3.67 ng/mL. We applied this sensor to determine MMP-9 in patient sera and obtained consistent results with the standard method. This strategy is expected to develop into a new method for diagnosing specific cancers related to MMP-9 and for evaluating the occurrence, development, and extent of cancer metastasis. Graphical abstract
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危险品化学品经营许可证（带存储）