International Journal of Environmental Science and Technology
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2023
·
IF 3.1
Zhou B.,Liu Z.,Li Y.,Lv G.,Wang L.,Liu H.,Liao L.
Chromium pollution in ground water is already very serious and needs to be solved urgently. In the present work, the products of natural pyrite after heat treatment were used as the reactive media for permeable reactive barrier. It found that natural pyrite can progressively convert to pyrrhotite with mixed monoclinic and hexagonal structures or pure hexagonal structure at different heat temperatures in argon atmosphere. The products heated at 600 °C had the highest removal of Cr 6+ as compared to pristine pyrite and other heated products. The column experiment showed the service life of the column was 480 PVs. The removal of Cr 6+ mechanisms under the batch and column conditions were also investigated in detail and both of them were redox reactions. The present work suggested that heat-treated natural pyrite has good application prospect as an efficient and low-cost reactive media material in permeable reactive barrier for chromium pollution control.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2023
·Vol. 415
·期 23
·5575-5588
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IF 4.3
Liu Yuanyuan,Han Yutong,Zhu Wenjie,Luo Qingming,Yuan Jing,Liu Xin
Glycosylation is one of the most common types of post-translational modifications in mammals. It is well known that N-glycans play a key role in cell adhesion, differentiation, synapsis, and myelination during the development of the mammalian central nervous system (CNS). Neuropathological symptoms (such as epilepsy and Alzheimer’s disease) are usually accompanied by N-glycosylation changes. In this study, we extracted N-glycan chains from eight regions of the mouse brain, and combined high-throughput, high-resolution matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) with the Fmoc N-hydroxysuccinimide ester (Fmoc-OSU) derivatization method to improve the sensitivity of glycan detection to characterize the total N-glycans in the mouse brain. A total of 96 N-glycan moieties were detected. An exhaustive examination of the relative abundance of N-glycans, coupled with a comparative analysis of differences, has uncovered discernible variations of statistical significance, including high mannose, fucosylated, sialylated, and galactosylated N-glycans. According to our investigations, a thorough and regionally specific cartography of glycans within the brain can facilitate the investigation of glycan-mediated mechanisms related to both the developmental trajectory and functional output of the brain. Additionally, this approach may serve as a basis for identifying potential biomarkers that are relevant to various brain-associated pathologies. Graphical Abstract
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CELLULOSE
·
2023
·Vol. 30
·期 12
·7877-7888
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IF 5.7
Gan Lin,Zheng Shuyu,Huang Jin
Gas adsorption materials, such as active carbon and zeolite, are known to cause second pollution after being used, due to their non-degradability. In this study, we prepared a degradable aerogel material based on cellulose nanocrystals (CNCs) and poly vinyl alcohol (PVA) with hierarchical pores and excellent CO \(_2\) -adsorption performance. The micropores, with specific area of 442 m \(^2\cdot\) g \(^{-1}\) , are obtained via in-situ growing MIL-100(Fe) on CNCs and concurrently assembling those CNC particles. The resulting aggregate is further introduced into degradable PVA aerogels, who offer mesopores and macropores. The resulting degradable material has a density of 0.216 g \(\cdot\) cm \(^{-3}\) and can adsorb 0.357 mmol CO \(_2\) per gram. This makes it a promising candidate for use in the preparation of light weight CO \(_2\) collectors.
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Nature Communications
·
2023
·Vol. 14
·期 1
·1-13
·
IF 16.6
Zheng Xiaozhong,Shi Xiaoyun,Ning Honghui,Yang Rui,Lu Bing,Luo Qian,Mao Shanjun,Xi Lingling,Wang Yong
Electrochemical hydrogen evolution reaction in neutral media is listed as the most difficult challenges of energy catalysis due to the sluggish kinetics. Herein, the Ir-H x WO 3 catalyst is readily synthesized and exhibits enhanced performance for neutral hydrogen evolution reaction. H x WO 3 support is functioned as proton sponge to create a local acid-like microenvironment around Ir metal sites by spontaneous injection of protons to WO 3 , as evidenced by spectroscopy and electrochemical analysis. Rationalize revitalized lattice-hydrogen species located in the interface are coupled with H ad atoms on metallic Ir surfaces via thermodynamically favorable Volmer-Tafel steps, and thereby a fast kinetics. Elaborated Ir-H x WO 3 demonstrates acid-like activity with a low overpotential of 20 mV at 10 mA cm −2 and low Tafel slope of 28 mV dec −1 , which are even comparable to those in acidic environment. The concept exemplified in this work offer the possibilities for tailoring local reaction microenvironment to regulate catalytic activity and pathway.
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Drug Delivery and Translational Research
·
2023
·
IF 5.4
Zhou Bo,Guo Zhendong,Zhao Peiwen,Wang Hao,Dong Siyan,Cheng Bo,Yang Jing,Li Binbin,Wang Xinyu
Type 2 diabetes is one of the major challenges that the world is facing today. However, metformin (MET) as most type 2 diabetics’ first-line oral hypoglycemic drug may cause serious side effects such as gastrointestinal irritation and nausea which reduce the patients’ medication compliance. Therefore, the aim of the study was to design a safe and effective self-treatment device for the delivery of MET. Here, a kind of coated microneedle (MN) patches based on poly(ethylene glycol)diacrylate (PEGDA) were prepared by a two-step casting method and photopolymerization process for transdermal administration of MET. The needles wrapped with drug-loaded hyaluronic acid (HA) coating showed promising mechanical properties and drug delivery ability that allowed them to penetrate the skin barrier for rapid drug delivery, and they had no skin irritancy. The in vivo experiment of type 2 diabetic rats showed a satisfying hypoglycemic effect of the coated MN patches. The study shows that the prepared MN patches will be a potential method for the treatment of type 2 diabetes in the future. Graphical Abstract
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JOURNAL OF POROUS MATERIALS
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2023
·
IF 2.6
Wu Wenrui,Wang Xin,Yan Yue,Zhang Hao,Xu Tao,Li Xianfu
The objective of this work was to prepare and evaluate Ni 3 S 4 /graphene nanostructures for making high-performance supercapacitor electrodes. A one-pot solvothermal method was developed to prepare the hierarchical nanostructures consisting of Ni 3 S 4 nanoflowers on graphene nanosheets. Due to the hierarchical structure of Ni 3 S 4 nanoflowers on graphene nanosheets, the resulting electrodes exhibited high supercapacitive performance. Herein, the Ni 3 S 4 /graphene electrode demonstrated the specific capacitance of 978.4 F g –1 at the current density of 0.5 A g –1 , the rate capability and long-term cycling stability were also excellent. Moreover, the capacitance contribution of NG-60 can reach 87.9% of the total capacity at 10 mV s −1 . The high pseudo-capacitive performance can be attributed to the superior electronic conductivity of graphene nanosheets and the well interconnected tiny pores/channels in the Ni 3 S 4 nanoflower arrays. The prepared Ni 3 S 4 /graphene hierarchical nanostructures may be promising as innovative electrode materials for making high-performance supercapacitors.
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Bio-Design and Manufacturing
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2023
·
IF 7.9
Lu Jingyi,Sun Miao,Zhang Jingyu,Yang Xiaofu,Dong Minyi,He Huihui,Liu An,Yu Mengfei,Wang Baixiang,Wang Huiming
Regeneration and reconstruction of bone tissue is always a challenge for clinicians due to the uncertainty of bone repair materials in terms of long-term and efficient effects on osteoblasts. Here, we propose a novel strategy combining benidipine, an antihypertensive drug and nanoparticles to synergistically promote the healing of bone defects. Loose and porous benidipine-loaded magnesium silicate nanoparticles were prepared and validated for their biosafety. The nanoparticles were efficiently taken up by preosteoblasts and uniformly distributed around the nucleus. After internalization into cells, the nanosystem is degraded by lysosomes, and the effect of promoting osteogenic differentiation is reflected by the continuous release of benidipine, silicon and magnesium ions. Our results clearly evaluated that the nanoflower-like magnesium silicate delivering benidipine tends to be more appropriate for the bone regeneration in preosteoblasts, indicating that it might be a potential approach in guiding bone repair in clinical applications. Graphic abstract
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Scientific Reports
·
2023
·Vol. 13
·期 1
·1-12
·
IF 4.6
Liu Yanhua,Liu Xingfei,Chen Juanning,Zhang Zhuanli,Feng Libang
Laserjet printing is a kind of facile and digital do-it-yourself strategies, which is of importance to fabricate inexpensive paper-based microfluidic devices. However, the printed hydrophobic barrier is not hydrophobic enough due to the weak hydrophobicity and requires subsequent heating, which can lead to the pyrolysis of cellulose in the paper and influence the detection results. Here, for the first time, we report a kind of functional toner including toner and polydopamine (PDA) nanocapsules which contains oleic acid modified ferric tetroxide (OA-Fe 3 O 4 ) and octadecylamine (ODA), which is suitable for printing with desired shapes and sizes to lead to formation of superhydrophobic barriers. Moreover, patterns printed with functional toner have good stability, including resistance to moisture, ultraviolet (UV) and bending. Finally, a proof-of-concept of metal and nitrite ions testing is demonstrated using colorimetric analysis, and the results show that the printed devices successfully perform instant detection of ions. The developed functional toner offers easy fabrication, cost-effectiveness and mass production of paper-based devices. In general, this strategy provides a new idea and technical support for the rapid prototyping of microfluidic paper-based analytical devices (μPADs) using laserjet printing.
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RESEARCH ON CHEMICAL INTERMEDIATES
·
2023
·
IF 3.3
Sun Bingnan,Wang Yajie,Yu Haoran,Zhang Lei,Zhang Weibing
In this work, dextranase was immobilized on the surface of hydroxyapatite nanowires (HAPNWs) through covalent cross-linking method. The prepared HAPNWs-NH 2 -dextranase was characterized by FE-SEM, XRD, TGA and FT-IR spectroscopy. The results show that the dextranase was successfully immobilized on HAPNWs by covalent cross-linking method. The properties of HAPNWs-NH 2 -dextranase were studied and compared with free dextranase, such as catalytic activity, kinetic constants, thermal stability and pH stability. The loading capacity, storage stability and reusability of the immobilized enzymes were investigated. HAPNWs-NH 2 -dextranase demonstrated better enzyme activity at higher temperatures (92.28% vs 33.08% at 70 °C) and higher pH stability (93.17% vs 57.78% at pH 7.0) than free dextranase. The loading capacity of dextranase on HAPNWs-NH 2 -dextranase can reach up to 868.2 mg g −1 . HAPNWs-NH 2 -dextranase retained 83.38% of its initial activity after 12 cycles, indicating that the HAPNWs-NH 2 -dextranase could have great performance in industry fields.
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Journal of Coatings Technology and Research
·
2023
·Vol. 20
·期 6
·1845-1856
·
IF 2.3
Zhang Liying,Gan Guoyou,Fan Peiyuan,Liu Yunchuan,Wang Tianwei,Li Weichao,Du Jinghong
Amine ligand, as one of the essential components of the Ag–amine complex, is necessary to reduce the sintering temperature and time of conductive inks. Herein, we report the facile preparation of hybrid amine conductive silver ink, mainly composed of silver oxalate–hybrid amine complex and methanol–acetone solvent. The synergistic effect of long-chain and short-chain amines enhances the uniformity of silver nanoparticles in the silver film. A uniformly conductive silver film is obtained by spin-coating as-prepared ink on the polyimide film, followed by thermal sintering. Then, the influence of butylamine content and sintering parameters on the physical properties and microstructure of silver film is systematically investigated. The resistivity of silver films, sintered at 170 °C for only 20 min, is found to be 6.71 μΩ·cm, which is four times higher than bulk silver. In addition, silver films after bending and adhesion test exhibit low resistivity and excellent adhesion. These results indicate that the hybrid amine conductive silver ink can provide promising opportunities for fabricating highly conductive flexible printed electronics at low temperatures in short times.
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Scientific Reports
·
2023
·Vol. 13
·期 1
·1-14
·
IF 4.6
Jiang Linlin,Niu Hui,Chen Yuan,Li Xing,Zhao Yulian,Zhang Chunhong,Li Minhui
Platycodon grandiflorum (Jacq.) A. DC. has been proposed as a medicine and food homology, thus playing an important role in disease prevention and health promotion, with great potential for research and value in clinical application. We aimed to analyze stakeholders' production behavior and financial performance from a value chain (VC) perspective and provide a basis for improving the quality of P. grandiflorum and the interests of stakeholders. P. grandiflorum collected from different producing areas were chemically analyzed, and the quality of platycodin D was evaluated. Rstudio3.6.0 was used to analyze the correlation between total platycodins (as platycodin D, platycoside E, and platycodin D 3 ) and platycodin D in P. grandiflorum , providing the basis for quality control of P. grandiflorum . In addition, we studied the anti-inflammatory and anti-cancer activities of P. grandiflorum extract under different links. Based on the food chain energy pyramid, the transfer efficiency of active components of P. grandiflorum in different links was studied. Accordingly, 10 different types of VCs were determined in producing P. grandiflorum . Our results show that vertical coordination has led to a more consistent traceability system and strict regulation of supply chains.
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Nature Communications
·
2023
·Vol. 14
·期 1
·1-8
·
IF 16.6
Chi Hongbin,Liu Yang,Li Ziyi,Chen Wanxin,He Yi
Flexible covalent organic frameworks (COFs) have been studied for applications containing sorption, selective separation, and catalysis. How to correlate the microscopic structure with flexibility in COFs is a great challenge. Herein, we visually track the flexible deformation behaviors of single COF-300 and COF-300-AR particles in response to solvent vapour guests with dark-field microscopy (DFM) in an in operando manner. COF-300-AR with freely-rotating C-N single bonds are synthesized by the reduction of imine-based COF-300 consisting of rigid C=N double bonds without changing topological structure and crystallinity. Unexpectedly, we observe that the flexible deformation of COF-300 is extremely higher than that of COF-300-AR despite it bears many C-N single bonds, clearly illustrating the apparent flexibility decrease of COF-300 after reduction. The high spatiotemporal resolution of DFM enables the finding of inter-particle variations of the flexibility among COF-300 crystals. Experimental characterizations by variable-temperature X-ray diffraction and infrared spectroscopy as well as theoretical calculations demonstrate that the flexible deformation of COF-300 is ascribed to the pedal motion around rigid C=N double bonds. These observations provide new insights into COF flexibility.
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