MICROCHIMICA ACTA
·
2017
·Vol. 184
·期 8
·2981-2990
·
IF 4.58
Wang Ting,Liu Siyu,Gao Guihua,Zhao Pan,Lu Nan,Lun Xiaowen,Hou Xiaohong
The authors describe a method for magnetic solid phase extraction (MSPE) combined with ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for the quantitation of eight non-steroidal anti-inflammatory drugs (NSAIDs) in wastewater and environmental water samples. Specifically, the NSAIDs were directly extracted by using a magnetic nanocomposite of type Fe 3 O 4 /MIL-101(Cr) (Matérial Institute Lavoisier, MIL) from 50 mL water samples without any further cleanup. The effects of the amount of adsorbent, pH value, salt concentration, ultrasonic extraction time, desorption solvent nature and volume and desorption time were investigated. Under the optimal conditions, UPLC-MS/MS based detection resulted in the following figures of merit: (a) Linear calibration plots that typically extend from 0.1 (0.2, 0.05, 0.02) to 50 μg·L −1 , depending on the compound; (b) detection limits between 3 to 60 ng·L −1 ; and (c), recoveries varying from 81.2% to 116.8% with relative standard deviations between 0.4% and 10.8%. The adsorption of NSAIDs on Fe 3 O 4 /MIL-101(Cr) was characterized by adsorption isotherms, kinetics and thermodynamics studies and provides a deeper insight into the adsorption mechanism. Compared to other method for pretreatment and preconcentration of NSAIDs, the new method is more rapid, sensitive, accurate and eco-friendly. The method was successfully applied to the determination of the NSAID residues in a variety of real environmental and wastewater samples.
Schematic of a method for determination of non-steroidal anti-inflammatory drugs (NSAIDs) in environmental water by magnetic solid phase extraction based on Fe 3 O 4 /MIL-101(Cr) combined with UPLC-MS/MS. The adsorption mechanism of NSAIDs on Fe 3 O 4 /MIL-101(Cr) was studied.
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LANGMUIR
·
2025
·
IF 3.9
Yingjie Ma,Baolei Liu,Dewen Sun,Dongfang Wang,Yabin Ma,Qianping Ran
SiO2/Fe3O4 hybrid wall microcapsules containing a paraffin core were successfully fabricated by Pickering emulsion template self-assembly and sol–gel technologies. The walls of these microcapsules were embedded with different dosages of Fe3O4 nanoparticles due to the effect of Fe3O4 Pickering emulsion of different concentrations. The resultant microcapsules exhibited a regular spherical morphology and a rough outer surface compared with that of the SiO2 wall. Thermal analysis indicated that the encapsulation efficiency (Een), thermal energy-storage efficiency (Ees), and thermal conductivity of paraffin@SiO2/Fe3O4 hybrid wall microcapsules prepared with 0.01 mol/L Fe3O4 Pickering emulsion [Pa@SiO2/Fe3O4-Ms (0.01)] increased by 16.71%, 16.88%, and 28.4% compared with those of paraffin@SiO2 microcapsules (Pa@SiO2-Ms), respectively. The phase-change temperatures and enthalpy of Pa@SiO2/Fe3O4-Ms (0.01) with an 80–100 μm particle size range changed little after 300 thermal cycles. At the same time, these microcapsules were introduced into water-based acrylic resin paint to prepare phase-change composite protective coatings (PCCPCs) and exhibited excellent thermoregulatory performance. The real-time temperature difference and temperature ramp rate of PCCPCs incorporating 5 wt % (80–100 μm) Pa@SiO2/Fe3O4-Ms (0.01) increased by 4.6 °C and decreased by 2.45 °C/min compared to that of the pure coating, respectively. Meanwhile, the fluctuation amplitude and fluctuation frequency of the average temperature on the back side of 5 wt % (80–100 μm) Pa@SiO2/Fe3O4-Ms (0.01)-PCCPCs decreased by 3.8 °C and extended by 395 s compared to that of the pure coating under one heating and cooling cycle, respectively. This study will provide great potential applications for addressing the risk of shrinkage deformation and cracking of the protected concrete substrates under high-frequency and large temperature difference conditions.
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JOURNAL OF ANALYTICAL CHEMISTRY
·
2026
·
IF 1.5
Sha Ou,Wu Yunfan,Xu Yuan,Yao Yang,Zhang Kaixuan,Fan Guangyu
In this study, an eco-friendly and dependable method based on magnetic solid-phase extraction and high-performance liquid chromatography equipped with ultraviolet detection was established to extract and determine chlorpromazine in milk. A novel composite material, Fe 3 O 4 @CS@AC, used as a magnetic adsorbent, was successfully synthesized via the chemical co-precipitation method and characterized. Various factors influencing the recovery of chlorpromazine were discussed and optimized. Moreover, Fe 3 O 4 @CS@AC for chlorpromazine exhibits a large adsorption capacity of 17.82 mg/g, and its mass transfer mechanism aligns more closely with the quasi-second-order kinetic model, dominated by chemisorption. Under optimal conditions, the linearity of chlorpromazine was investigated in the range of 0.01–5.00 mg/L, with a coefficient of determination greater than 0.9995, and the limit of detection was 2.47 × 10 –3 mg/L. The feasibility of the developed method was evaluated by analyzing and detecting chlorpromazine in different milk samples, with recoveries of 90.76–96.72% and relative standard deviation of 2.01–4.23%. This method, with straightforward operation and good reproducibility, was successfully applied for the analysis and determination of trace chlorpromazine in milk, providing a promising avenue for the development and application of novel adsorbents in milk analysis.
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JOURNAL OF ANALYTICAL CHEMISTRY
·
2023
·Vol. 78
·期 2
·213-221
·
IF 1.1
Suo Lili,Hu Meihua
Abstract A new specific sorbent entitled molecularly imprinted polymer (Fe 3 O 4 @PDA MIP) was fabricated on the surface of ferroferric oxide nanoparticles with the dummy template of 5,7-dimethoxycoumarin through self-assembly of dopamine which is efficient for recognition and determination of aflatoxin B in food samples coupled with UPLC-FLD with a large volume flow cell. The prepared MIPs were characterized, and the adsorption properties were evaluated. The maximum adsorption capacities were 0.46 mg/g for aflatoxin B1 and 0.047 mg/g for aflatoxin B2. Under optimized conditions, the calibration plots are linear in the range of 0.005–0.5 and 0.001–0.1 ng/mL with LODs of 0.0024 and 0.0004 ng/mL for aflatoxin B1 and aflatoxin B2, respectively. The recoveries from spiked samples are 89.0–105.0% with RSDs of 5.6–7.7% in case of corn, peanut and edible oil. And after 7 cycles, the adsorption capacity of the MIPs did not decrease significantly.
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International Journal of Nanomedicine
·
2023
·
IF 8
Fangqing Wang,Nianlu Li,Wenbo Wang,Long Ma,Yaru Sun,Hong Wang,Jinhua Zhan,Dexin Yu
Purpose Owing to lack of specific molecular targets, the current clinical therapeutic strategy for triple negative breast cancer (TNBC) is still limited. In recent years, some nanosystems for malignancy treatment have received considerable attention. In this study, we prepared caramelized nanospheres (CNSs) loaded with doxorubicin (DOX) and Fe3O4 to achieve the synergistic effect of combined therapy and real-time magnetic resonance imaging (MRI) monitoring, so as to improve the diagnosis and therapeutic effect of TNBC.Methods CNSs with biocompatibility and unique optical properties were prepared by hydrothermal method, DOX and Fe3O4 were loaded on it to obtain Fe3O4/DOX@CNSs nanosystem. Characteristics including morphology, hydrodynamic size, zeta potentials and magnetic properties of Fe3O4/DOX@CNSs were evaluated. The DOX release was evaluated by different pH/near-infrared (NIR) light energy. Biosafety, pharmacokinetics, MRI and therapeutic treatment of Fe3O4@CNSs, DOX and Fe3O4/DOX@CNSs were examined in vitro or in vivo.Results Fe3O4/DOX@CNSs has an average particle size of 160 nm and a zeta potential of 27.5mV, it demonstrated that Fe3O4/DOX@CNSs is a stable and homogeneous dispersed system. The hemolysis experiment of Fe3O4/DOX@CNSs proved that it can be used in vivo. Fe3O4/DOX@CNSs displayed high photothermal conversion efficiency, extensive pH/heat-induced DOX release. 70.3% DOX release is observed under the 808 nm laser in the pH = 5 PBS solution, obviously higher than pH = 5 (50.9%) and pH = 7.4 (less than 10%). Pharmacokinetic experiments indicated the t1/2β, and AUC0–t of Fe3O4/DOX@CNSs were 1.96 and 1.31 -fold higher than those of DOX solution, respectively. Additionally, Fe3O4/DOX@CNSs with NIR had the greatest tumor suppression in vitro and in vivo. Moreover, this nanosystem demonstrated distinct contrast enhancement on T2 MRI to achieve real-time imaging monitoring during treatment.Conclusion Fe3O4/DOX@CNSs is a highly biocompatible, double-triggering and improved DOX bioavailability nanosystem that combines chemo-PTT and real-time MRI monitoring to achieve integration of diagnosis and treatment of TNBC.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Chuan Cao,Yanjun Guo,Dadi Chen,Jun Cui,Xiang Hu
Conventional heterogeneous iron-based catalysts face challenges such as insufficient catalytic activity, sluggish Fe(Ⅲ)/Fe(Ⅱ) cycle, and hindered electron transfer during Fenton catalytic reactions. Herein, Fe 3 O 4 /Fe 0 /Fe 3 C-2-600, obtained by calcining MIL-88B (Fe) in-situ growth on stainless-steel mesh at varying temperatures, was served as a catalytic electrode in a dual-cathode electro-Fenton system. The catalytic mechanism was elucidated by density functional theory (DFT) calculations. Based on the calculations, the presence of Fe 0 could induce electron transfer to Fe(Ⅲ), accelerating the Fe(Ⅲ)/Fe(Ⅱ) cycle. Simultaneously, Fe 0 was functioned as an electron transfer station, rapidly exporting electrons from the internal Fe 3 O 4 core to the surface graphite layer, further activating H 2 O 2 . Due to the rapid electron transfer, the Fe 3 O 4 /Fe 0 /Fe 3 C-2-600 cathodes demonstrated remarkable catalytic activity, achieving a 97.7 % degradation of tetracycline (TC) within 12 min. According to electron spin resonance tests and quenching experiments, hydroxyl radicals (·OH) was identified as the main active species. In addition, the possible degradation pathways of TC were proposed, according to the results of high-performance liquid chromatography-mass spectrometry (HPLC-MS). The Fe 3 O 4 /Fe 0 /Fe 3 C-2-600 cathode presented a promising strategy for developing an efficient and straightforward method to construct internal electric fields that could accelerate electron transfer in Fenton reactions. Moreover, the integration with the double-cathode electro-Fenton system, realizes the concept of reagent-free and sustainable catalysis, enhancing its practical application value.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Xiyue Xue,Yanpeng Chen,Yuxin Xiao,Saidi Wang,Hongjie Zhang,Jin Wang,Wen-Hui Zhang
This study pioneers a sustainable “waste-to-wealth” strategy for fabricating a high-performance, pH-universal Fenton-like catalyst (FeCu 2 @BC T4 ) through the one-step co-pyrolysis of acid-precipitated black liquor (APBL) and Fenton sludge with a copper precursor. The innovation lies in the precise engineering of a Fe 0 /Fe 3 O 4 heterojunction synergistically coupled with Cu 0 nanoparticles on a functional APBL-derived biochar. By tuning the Cu/Fe mass ratio and pyrolysis time, the phase composition and electron-transfer properties were optimized. The resulting catalyst exhibits exceptional activity and stability across a broad pH range (3–9), achieving >92.3% methylene blue degradation within 60 min, and demonstrates superior removal efficiency toward various cationic dyes (rhodamine B, crystal violet, malachite green) and an anionic dye (methyl orange). Mechanistic investigations reveal a clear pH-governed transition of reactive oxygen species (ROS) pathways: under acidic conditions (pH 3), •OH-dominated homogeneous–heterogeneous catalysis prevails; under neutral conditions, the system shifts to a heterogeneous process driven by synergistic •OH/ 1 O 2 oxidation. This unique ROS switch is sustained by efficient electron mediation from the biochar matrix, coupled with robust electron supply and transfer enabled by the Fe 0 /Fe 3 O 4 heterojunction and Fe Cu galvanic coupling. This work provides a novel paradigm for converting industrial solid wastes into advanced catalytic materials with a well-elucidated mechanism, effectively overcoming the critical pH limitation of conventional Fenton technologies and showing broad application prospects for organic wastewater remediation.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2026
·
IF 5.4
Qing Jin,Kai Ma,Guilong Gao,Xinyu Zhou,Lijie Xu,Ying Zhang,Jiangtao Shi,Lu Gan
In this study, a series of carbon nanofiber (CNF) based one-dimensional catalysts were prepared by pyrolyzing MIL-88B(Fe) anchored PAN/lignin electrospun nanofibers, which were then employed to activate peroxymonosulfate (PMS) for bisphenol A (BPA) degradation. The results indicated that adjusting the lignin content in nanofiber precursor could engineer the crystalline phase of iron compounds in the catalysts, as well as their catalytic activity and stability. Specifically, the precursor with lower lignin content was converted into Fe 3 O 4 loaded CNF (P2L1-Fe-C), whereas Fe 3 C loaded CNF was obtained (P1L1-Fe-C) by increasing lignin content to 50 wt% in the nanofiber precursor. Having multiple Fe valence states within Fe 3 C which facilitated internal electron transfer, P1L1-Fe-C exhibited high catalytic activity with high stability and low iron ion leaching when activating PMS for BPA degradation. P1L1-Fe-C/PMS system could produce more kinds of active species including hydroxyl radical (•OH) and multiple non-radical species like singlet oxygen ( 1 O 2 ), high-valent iron-oxo species, and electron transfer process. Comparatively, P2L1-Fe-C/PMS system was only able to produce •OH and 1 O 2 . The existence of more BPA degradation pathways resulted in enhanced resistance of P1L1-Fe-C/PMS system towards various environmental interferences. This study inspires a new thinking of developing iron based Fenton-like catalyst with tunable crystalline phases through precursor recipe regulation, achieving both high activity and stability. Download: Download high-res image (225KB) Download: Download full-size image
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CHROMATOGRAPHIA
·
2021
·Vol. 84
·期 11
·1065-1075
·
IF 2.044
Zhang Zixin,Wang Zhida,Zhang Ying,Zhang Yi,Han Lifeng,Tian Fei
We present a facile approach for the direct attachment of cross-linked poly(2-thiopheneacetic acid) onto the surface of magnetite nanoparticles with one single carbon layer (Fe 3 O 4 @1C NPs) via self-assembly oxidative polymerization. The functional Fe 3 O 4 @1C NPs combined with poly(2-thiopheneacetic acid) [Fe 3 O 4 @1C@ poly(Th) NPs] was successfully prepared and used for magnetic solid-phase extraction (MSPE). The influence of the preparation conditions and extraction conditions were investigated in detail. The morphology and size distribution of the monolithic materials were characterized by transmission electron microscopy. Under the optimized experimental conditions, the prepared Fe 3 O 4 @1C@ poly(Th) NPs showed good extraction efficiency for canthin-6-one alkaloids. Furthermore, the results indicated that the binding specificity and selectivity of the Fe 3 O 4 @1C@ poly(Th) NPs might be attributed to electrostatic interactions and pore structure. A MSPE–HPLC method was also developed for quantitative analysis of canthin-6-one alkaloids. The developed method showed good linearity, low limit of detections, low limit of quantifications, and good reproducibility over a wide linear range. To further prove the utility, Fe 3 O 4 @1C@ poly(Th) NPs-MSPE was also used to extract canthin-6-one alkaloids from Eurycoma longifolia stems, with a recovery rate of 87.9–114%. Thus, this method is potentially applicable for the extraction of similar alkaloid compounds from medicinal herb samples.
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Nanomaterials
·
2018
·Vol. 8
·期 7
·466
·
IF 3.504
Yang Luo,Wei Zhang,Zhengfang Liao,Shengnan Yang,Shengtao Yang,Xinhua Li,Fang Zuo,Jianbin Luo
Core-shell (C/S) structured upconversion coated Fe3O4nanoparticles (NPs) are of great interest due to their potential as magnetic resonance imaging (MRI) and upconversion luminescent (UCL) imaging agents, as well as near-infrared activated photodynamic therapy (PDT) platforms. When C/S structured Fe3O4@Mn2+-doped NaYF4:Yb/Er NPs were prepared previously, well-defined C/S-NPs could not be formed without the doping of Mn2+during synthesis. Here, the role of Mn2+doping on the synthesis of core-shell structured magnetic-upconversion nanoparticles (MUCNPs) is investigated in detail. Core-shell-shell nanoparticles (C/S/S-MUCNPs) with Fe3O4as the core, an inert layer of Mn2+-doped NaYF4and an outer shell consisting of Mn2+-doped NaYF4:Yb/Er were prepared. To further develop C/S/S-MUCNPs applications in the biological field, amphiphilic poly(maleic anhydride-alt-1-octadecene) (C18PMH) modified with amine functionalized methoxy poly(ethylene glycol) (C18PMH-mPEG) was used as a capping ligand to modify the surface of C/S/S-MUCNPs to improve biocompatibility. UCL imaging, T1-weighted MRI ascribed to the Mn2+ions and T2-weighted MRI ascribed to the Fe3O4core of C/S/S-MUCNPs were then evaluated. Finally, chlorine e6 (Ce6) was loaded on the C/S/S-MUCNPs and the PDT performance of these NPs was explored. Mn2+doping is an effective method to control the formation of core-shell structured MUCNPs, which would be potential candidate as multifunctional nanoprobes for future T1/T2-weighted MR/UCL imaging and PDT platforms.Keywords:Mn2+;Fe3O4;upconversion;core-shell-shell;MR/UCL imaging;PDT platforms
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TALANTA
·
2017
·
IF 4.162
Xiaoling Yang,Kexin Qiao,Fang Liu,Xiaoling Wu,Miyi Yang,Jing Li,Haixiang Gao,Sanbing Zhang,Wenfeng zhou,Runhua Lu
In this research, a novel method using magnetic mixed hemimicelles dispersive solid-phase extraction (MMHDSPE) based on C 16 mimBr-coated attapulgite/polyaniline-polypyrrole/Fe 3 O 4 (ATP/PANI-PPY/Fe 3 O 4 ) nanocomposites were investigated for enrichment and separation of three acaricides in fruit juice. In this method, we combined the simplicity and speed of dispersive solid-phase extraction, the advantages of mixed hemimicelles and the facility of the phase separation of the magnetic nanoparticles to develop a simple, rapid, sensitive, and effective method for detecting target analytes from the juice samples. ATP/PANI-PPY/Fe 3 O 4 nanocomposites were successfully synthesized using a one-pot method. The as-prepared nanocomposite sorbents were characterized by Fourier transform infrared spectra (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The experimental factors affecting the extraction efficiency including the sorbent type, amount of ATP/PANI-PPY/Fe 3 O 4 nanocomposites, volume of ILs , sonication time, pH, and desorption conditions were optimized. Under the optimal conditions, good linearity was observed for all target analytes, with correlation coefficients (r 2 ) ranging from 0.9994 to 0.9999; the limits of detection (LOD) were in the range of 0.16–0.57 μg L −1 , and the recoveries of analytes using the proposed method ranged between 88.67% and 95.10%. The sorbents exhibited excellent repeatability in the range of 1.83–4.24% in extracting the three target analytes. In addition, the intra-day and inter-day precision values were found to be in the range of 0.19–6.24% and 2.23–8.36%, respectively. The method was successfully applied to analyze fruit juice samples by rapid preconcentration of acaricides.
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JOURNAL OF SEPARATION SCIENCE
·
2015
·Vol. 38
·期 12
·2167-2173
·
IF 2.737
Xi Wang,Ning Chen,Qing Han,Zaiyue Yang,Jinhua Wu,Cheng Xue,Junli Hong,Xuemin Zhou,Huijun Jiang
A facile adsorbent, a nanocomposite of Fe 3 O 4 and reduced graphene oxide, was fabricated for the selective separation and enrichment of synthetic aromatic azo colorants by magnetic solid-phase dispersion extraction. The nanocomposite was synthesized in a one-step reduction reaction and characterized by atomic force microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, X-ray diffraction and Brunauer–Emmett–Teller analysis. The colorants in beverages were quickly adsorbed onto the surface of the nanocomposite with strong π–π interactions between colorants and reduced graphene oxide, and separated with the assistance of an external magnetic field. Moreover, the four colorants in beverages were detected at different wavelengths by high performance liquid chromatography with diode array detection. A linear dependence of peak area was obtained over 0.05–10 μg/mL with the limits of detection of 10.02, 11.90, 10.41, 15.91 ng/mL for tartrazine, allure red, amaranth, and new coccine, respectively (signal to noise = 3). The recoveries for the spiked colorants were in the range of 88.95–95.89% with the relative standard deviation less than 2.66%. The results indicated that the nanocomposite of Fe 3 O 4 and reduced graphene oxide could be used as an excellent selective adsorbent for aromatic compounds and has potential applications in sample pretreatment.
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高影响因子
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