INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2024
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IF 8.1
Shaopei Jia,Yanfeng Gao,Xiaofei Ma,Quan Huang,Qian Zhang,Xiaozhe Cheng,Qisong Li,Yan Zhang,Wei Cheng,Menghui Liu,Yunchao Mu
Designing and synthesizing cost-effective hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) catalysts is still the critical impetus for electrocatalytic alkaline water splitting for green hydrogen production. We present a novel strategy to synthesize Ni 12 P 5 –Ni 2 P heterojunction nanoparticles anchored in the three-dimensional (3D) graphene composite bonded by N–P co-doped porous carbon (NPC) through a single high-temperature carbonization. The as-obtained Ni 12 P 5 –Ni 2 P@NPC/3DG possessed an open pore structure, promoting electrolyte diffusion and enhance bubble release. The synergistic effect of the Ni 12 P 5 –Ni 2 P heterojunction with high intrinsic catalytic activity and the N–P co-doped carbon enabled the composite to exhibit high catalytic activity and stability for HER and OER. The optimized Ni 12 P 5 –Ni 2 P@NPC/3DG-0.5 exhibited overpotentials of 209.8/206.1 mV at 10 mA cm −2 and Tafel slopes of 67.9/92.3 mV dec −1 for HER/OER. Furthermore, when Ni 12 P 5 –Ni 2 P@NPC/3DG-0.5 was used as both the cathode and anode for overall water splitting, the cell only required a low voltage of 1.58 V to achieve a current density of 10 mA cm −2 , which was comparable to the catalytic activities of commercial noble metal catalysts. Meaningfully, this synthetic method provided a new strategy to improve electrocatalytic performance of Ni-based phosphides, extensively promoting the development of highly efficient electrocatalysts for alkaline overall water splitting.
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CARBOHYDRATE RESEARCH
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2024
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IF 2.4
Lin Wang,Yu Pang,Zhongwen Su,Meihua Xin,Mingchun Li,Yangfan Mao
N -(sodium 2-hydroxypropylsulfonate) chitosan (HSCS), N -sulfonate chitosan (SCS) and N -isonicotinic sulfonate chitosan (ISCS) were prepared. The structures of the prepared chitosan derivatives were characterized by nuclear magnetic resonance ( 1 H NMR) spectroscopy, Fourier transform infrared (FTIR) spectroscopy, ultraviolet–visible (UV–vis) spectroscopy and elemental analysis (EA). Antibacterial and antibiofilm activities of these chitosan derivatives were evaluated in vitro . The minimum inhibitory concentration (MIC) of HSCS and SCS against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) were 0.625 mg/mL and 0.156 mg/mL, respectively. ISCS exhibited MIC values of 0.313 mg/mL and 0.078 mg/mL against E. coli and S. aureus , respectively. ISCS demonstrated superior antibacterial and antibiofilm properties compared to SCS and HSCS. These findings suggest that the incorporation of a pyridine structure into sulfonate chitosan enhances its antibacterial and antibiofilm activities, and the prepared ISCS has a promising application prospect for controlling the reproduction of microorganisms in the field of food packaging.
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Cong Zhang,Rui Cui,Liang Qi,Minhua Zong,Canyu Zhang,Yufei Cao,Wenyong Lou
Pickering emulsions, with their high specific surface area, serve as promising nanoreactors for highly efficient biocatalysis. These emulsions also provide an effective way to integrate multiple incompatible catalysts, such as enzymatic catalysis and metal catalysis, paving the way for green synthetic chemistry in the future. In this study, we used agar, an accessible and biodegradable material, to produce agar nanoparticles with varying properties by modifying them with phthalic anhydride. The agar nanoparticle-stabilized Pickering emulsion greatly enhanced the lipase-catalyzed esterification reaction, demonstrating 392- and 38-fold improvements compared with monophasic and biphasic catalytic systems, respectively. After 10 reuse cycles of the Pickering emulsion, the product yield remained 86.5 %, with the relative enzyme activity being 86.6 %. Furthermore, we successfully integrated lipase-catalyzed esterification and Pd-catalyzed C C coupling reactions within the Pickering emulsion. By increasing the interfacial reaction area and reducing the mass transfer distance, this system improved the efficiency of the chemoenzymatic cascade reaction. The agar-based Pickering emulsion provides a promising platform for efficient and sustainable green synthesis, utilizing enzyme catalysts or chemical-biological hybrid catalysts.
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SENSORS AND ACTUATORS B-CHEMICAL
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2025
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IF 7.7
Lei Wang,Jinning Fan,Shangcong Gu,Yan Zhang,Yan Huang,Guiyi Yang,Keyi Li,Songfang Zhao,Zhiqiang Liu,Duxia Cao
Pyrosulfite, a widely used food additive known for its dual functions as both a preservative and antioxidant, is extensively applied in various fields, including food preservation, and pharmaceutical industry. However, excessive use may pose potential risks to human health. Here, a near-infrared fluorescence probe, 4-(1-cyano-4-(4-(dimethylamino-phenyl)-buta-1,3-dienyl)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyridinium, iodide, named CPB was first developed. It triggers a near-infrared fluorescence (700 nm) quenching reaction with pyrosulfite in almost pure buffered solution through nucleophilic addition of the C C bond. This probe was effectively used for the quantitative monitoring of pyrosulfite in various foods and living cells, demonstrating high sensitivity. A near-infrared ratiometric fluorescent detection system for pyrosulfite was then successfully constructed by combining CPB and 3-(7-diethylamino-2-oxo-2 H -chromen-3-yl)-2-pyridin-4-yl-acrylonitrile ( CPA ) fluorescent compound. The ratiometric fluorescent detection system of the hydrogel-encapsulated probes has been successfully employed for the quantitative analysis of pyrosulfite with high sensitivity (detection limit: 0.12 µM), being able to keenly capture minor concentration changes. The system equipped with the two probes has also shown potential applications in anti-counterfeit ink.
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Journal of Environmental Chemical Engineering
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2025
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IF 7.2
Yalin Zhang,Meng Lyu,Yanhui Dou,Xinlong Liu,Zongzeng Yang,Xiaoyuan Liao
The development of degradable plastic has emerged as a critical strategy to address plastic pollution. This study focuses on polybutylene adipate terephthalate (PBAT) as the subject of investigation, systematically exploring its degradation behavior and microbial mechanisms in soil environments. Microorganisms such as Escherichia coli ( E. coli ), Staphylococcus aureus ( S. aureus ), and Bacillus flexus ( B. flexus ) were introduced, and the degradation efficiency and mechanisms of PBAT were analyzed under varying conditions of temperature (45, 55, and 65 ℃), ventilation (100 and 200 mL/min), and burial depth. The experimental results revealed that E. coli , under 100 mL/min ventilation at 55 ℃, exhibited the highest degradation efficiency, with a weight loss rate of 16.45% in 30 days, significantly outperforming the other strains ( S. aureus : 12.49%; B. flexus : 3.54%). It was found that the presence of surface cracks and ester bond (C=O, 1710 cm⁻¹) rupture by SEM and FTIR analysis, and degradation occurs preferentially in the amorphous zone and that crystallinity increases throughout the degradation process by XRD and DSC results. This study elucidates PBAT degradation was catalyzed by microorganisms through the secretion of key enzymes providing a novel foundation for optimizing the environmental application of degradable plastic and advancing green technology development.
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Journal of Oleo Science
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2025
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IF 1.8
Lin Gu,Yuan Gao,Wenxin Li,Jianing Liu,Danyang Wang,Yongjie Chi,Jing Zhang,Qingyan Gai,Habiba Nazir,Qingye Jia,Huimei Wang,Lianyan Wang
Ozonized sunflower oil has been found to have a valuable antimicrobial activity against bacteria, viruses, and fungi. However, delayed cutaneous wound healing, severe adverse skin reactions such as pain, burns, irritation, and unsatisfactory storage stability have limited its clinical use as it is known that the performance of ozonized sunflower oil is reflected by core indicators such as iodine value (IV), peroxide value (PV), and acid value (AV). Aiming to improve the above characteristics, ozone oxidation conditions such as the oil water content of raw materials, stirring speed, and ozonized time were successfully optimized, and the optimized conditions were 5%, 300 rpm, and 6 h, respectively. Additionally, the UHPLC-Q-Exactive Orbitrap MS was used to identify the compounds of sunflower oil and ozonation sunflower oil, and 10 fatty acids were successfully identified. The results clearly indicated that the ozonized sunflower oil prepared under optimized ozonation conditions achieved a high degree of ozonation (II) and a satisfactory PV/AV ratio. These optimized conditions further proved to be valuable in improving not only the storage stability of ozonized sunflower oil for up to six months but also in ensuring its remarkable antimicrobial effects on Staphylococcus aureus and Candida albicans, with a PV of 165.75 mmol/kg achieving a 100% antibacterial efficacy.
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JOURNAL OF MEMBRANE SCIENCE
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2025
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IF 9
Zhaoqian Zhang,Shaopeng Xin,Qiaoxia Hu,Yunxia Hu
Proteins have emerged as promising materials to fabricate advanced separation membranes due to natural abundance, high biocompatibility, and precisely defined molecular structures. However, existing studies have primarily focused on enhancing membrane performance using proteins, with limited investigation into the mechanism of membrane-formation and structure-performance relationship of protein-based membranes. In this study, lysozyme (Lyz) and hemoglobin (BHb) were co-assembled to construct defect-free, tunable nanofiltration membranes with sub-10 nm pore sizes. The assembly behaviors in solutions, on solid substrates and on porous substrates were investigated. It is demonstrated that the membrane formation is predominantly governed by interface-induced planar growth of protein assembled nanofilms. The BHb electrostatically interacts with Lyz to tailor the pore structure of the protein assembled nanofilm, ultimately leading to the formation of programmable Lyz/BHb membranes. Furthermore, systematic optimization of key parameters including protein concentration and pH enables precise control over structure and performance of membranes. The protein membrane without defects and nanoparticles could be created by protein co-assembly with short time and multi-layer growth. The resulting Lyz/BHb membranes exhibit exceptional tunability in nanometer, with pore sizes at 1.4–6.0 nm and water permeance varying from 39 to 310 L⸱m −2 ⸱h −1 ⸱bar −1 . These protein-based membranes demonstrate high efficiency in diverse separation tasks, including protein retention, dye recovery, and antibiotic removal. This work provides a versatile and simple method for tailoring properties of protein-based membranes, offering promising opportunities for the development of customized separation membranes for various industrial and environmental applications.
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International Journal of Refrigeration
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2025
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IF 3.8
Shiya Lin,Yiqi Xie,Xianyang Chen,Pengcheng Lin,Ying Chen
Advanced cold chain systems are essential for maintaining nutritional integrity and reducing spoilage in perishable fruits. However, conventional mechanical refrigeration incurs considerable energy consumption and operational costs. This study introduces a green, safe, and cost-effective alternative—Brine Phase Change Cold Storage Gels (BPCCSGs). With a low phase change temperature (−11.29 °C), high latent heat (242.14 J·g⁻¹), and elevated thermal conductivity (0.835 W·m⁻¹·K⁻¹), BPCCSGs are well-suited for cold chain applications involving subtropical fruits. Additionally, the risk of cold storage material leakage and its consequent detriment to fruit safety could be significantly reduced by using our state-of-the-art gel packaging technique. Gel-based encapsulation effectively minimized leakage risk and prevented potential contamination. Pre-charging BPCCSGs during off-peak hours significantly improved energy and cost efficiency (3.82 × 10⁻⁵ $·J⁻¹), while reducing environmental burden. Moreover, the improvement in thermal conductivity and the optimization of the spatial layout facilitated temperature uniformity of BPCCSGs at cold storage scenarios. Finally, the integration of a 5G-enabled sensor system enabled real-time monitoring of temperatures and locations. The system was successfully deployed in waxberry logistics, ensuring real-time traceability and maintaining fruit quality, highlighting its potential for next-generation cold chain systems.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Die Yang,Qi Luo,Chaoyi Li,Yiruo He,Derong Li,Zhilang Xu,Liming Ge,Changdao Mu,Defu Li
Pathogenic bacteria associated infection is a major cause of guided bone regeneration (GBR) treatment failure clinically. Antibacterial GBR membranes are promising strategies for addressing bacterial infection risk in bone repair. Here, an antibacterial heterogeneous bilayer collagen-based membrane (CDCP) was fabricated by controlling the crosslinking density between collagen and dialdehyde carboxymethyl cellulose (DCMC), which was composed of a porous layer containing nano-hydroxyapatite (nHap) to mimic bone's organic-inorganic composition, and a dense layer loading with chlorhexidine-carrying nanoparticles (CHX@mPDA NPs) to endow membrane with sustained antibacterial activity. CDCP membrane demonstrated good hemostasis and osteoblast/fibroblast cytocompatibility, besides drastically improved mechanical strength and biodegradation stability. CDCP membrane possessed robust broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria due to the sustained release of antibacterial drug CHX. CDCP membrane with dense network structure had strong physical barrier function against the inward growth of L929 cells, while the loose porous layer demonstrated significant induction in osteogenic differentiation of BMSCs. CDCP membrane had a significant promoting effect in bacteria-infected bone repair based on the synergistic effects of its powerful in vivo antibacterial activity and unique heterogeneous bilayer structure. Overall, CDCP membrane held potential application value and broad development prospects in the field of bacteria-infected bone repair.
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MACROMOLECULAR RESEARCH
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2025
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IF 3.4
Liu Jinlong
Traditional lignin-silver nanoparticle hydrogels are often limited by slow gelation (> 3 h), weak mechanical properties, and limited antibacterial efficacy. In this study, we introduce a novel approach by incorporating metal ions (Fe 3+ and Al 3+ ) into lignin-silver nanoparticle (AgNP) composites embedded in an acrylic acid (AA) matrix. This modification significantly enhances the hydrogel's multifunctionality. The presence of metal ions accelerates gelation, enabling rapid formation of highly crosslinked structures within seconds, a notable improvement over conventional lignin-based hydrogels, which typically exhibit slower gelation. Detailed characterization using SEM, FTIR, and XPS analyses reveals that metal ions interact with lignin moieties, inducing redox reactions and coordinating with functional groups, such as phenolic hydroxyl and carboxyl groups. The Fe 3+ -based hydrogel demonstrates potent antibacterial activity, driven by reactive oxygen species (ROS) generation (MIC = 1 mg/mL and MBC = 2 mg/mL against Escherichia coli and Staphylococcus aureus , respectively), while the Al 3+ -based hydrogel shows enhanced mechanical resilience, maintaining 95% recovery after compression. Compared to conventional lignin@AgNPs-AA hydrogels, both hydrogels exhibit remarkable multifunctional properties, including 2.5 × higher compressive strength, 90% DPPH radical scavenging activity, and improved stability. Mechanistic studies highlight distinct antibacterial pathways: Fe 3+ promotes oxidative stress through Fenton reactions, while Al 3 ⁺ disrupts bacterial membranes. This work establishes a rapid, metal-ion-catalyzed approach for the development of lignin-based hydrogels, addressing previous limitations and offering promising applications in wound healing, sensors, and environmental remediation. Graphical abstract
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2025
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IF 5.6
Meixin Wang,Xingguo Liu,Jingyuan Song,Liping Wang,Lianghai Hu
Peptide therapeutics have demonstrated remarkable efficacy in the treatment of metabolic disorders (GLP-1 analogs), cancers (targeted tumor receptor inhibition), and infectious diseases (antimicrobial/viral entry blockade mechanisms), yet their clinical application remains constrained by rapid in vivo degradation and limited transmembrane permeability due to macromolecular polarity. To address these challenges, we developed a biomimetic nano-delivery system (EV@DhHP-6-MIP) synergizing milk-derived extracellular vesicles (EVs) with molecularly imprinted mesoporous silica through ultrasound-assisted membrane fusion technology. The molecularly imprinted mesoporous silica, featuring surface-imprinted binding sites on its ordered 3.1 ± 0.3 nm channels, achieved high-efficiency loading of the antioxidative peptide DhHP-6. The EVs enhanced targeted delivery via CD63/TSG101 transmembrane protein-mediated receptor-dependent endocytosis, while their natural phospholipid bilayer structure minimized immunogenicity compared to synthetic carriers. Leveraging milk as a renewable resource, this system ensured scalable production feasibility. In vitro evaluation using human embryonic kidney 293 T cells—selected for their well-characterized endocytic mechanisms and stable oxidative stress response—demonstrated that EV@DhHP-6-MIP reduced intracellular ROS levels by 38.5 %. For in vivo validation, Caenorhabditis elegans , which shares evolutionarily conserved oxidative stress pathways with humans, was employed. EV@DhHP-6-MIP treatment extended nematode survival time by 31.2 % under paraquat-induced oxidative stress and reduced intestinal lipofuscin accumulation by 40.47 %, without observable reproductive toxicity. This system resolves the longstanding conflict between protective encapsulation and bioavailability enhancement in peptide drug delivery through a tripartite synergistic mechanism: mesoporous silica-enabled drug stabilization, molecular imprinting-driven controlled release, and EV-mediated efficient delivery. Our work establishes a theoretical paradigm for developing intelligent nano-drug delivery systems with high efficacy and low toxicity, thereby holding significant translational value.
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2025
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IF 5.6
Lei Huang,Xin Ling,Linhui Huang,Feng Wei,Santosh K Tiwari,Xinyu Chen,Fei Ma,Fangdi Huang,Nannan Wang,Yanqiu Zhu,Dahai Yu
In pursuit of a sustainable alternative to conventional petroleum-derived polymers, this study aims to enhance the comprehensive performance of polylactic acid (PLA). Despite its inherent biocompatibility and biodegradability, the intrinsic brittleness of PLA significantly restricts its broader applicability, particularly in the medical domain. To overcome this limitation, we utilized the Hummers method to functionalize the surface of carbon nanotubes (CNTs) with carboxylic acid groups, followed by a green and highly efficient solution-mixing approach to immobilize the modified CNTs onto the surface of HKUST-1, a metal-organic framework (MOF). The resulting inorganic-organic nanocomposite, denoted as CNTₘ/HKUST-1, was uniformly integrated into a PLA matrix via a mechanical hot-pressing technique, yielding the CNTₘ/MOF-PLA composite. This composite exhibited remarkable enhancements in mechanical properties, including tensile strength, modulus, and fracture toughness, alongside improved thermal stability. Furthermore, it demonstrated exceptional antibacterial efficacy against *Staphylococcus aureus* and Escherichia coli, coupled with outstanding biocompatibility and minimal cytotoxicity. The green synthesis strategy employed herein positions the CNTₘ/MOF-PLA composite as a highly promising material for applications in tissue engineering and advanced biomedical devices.
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