RSC Advances
·
2014
·Vol. 4
·期 48
·25183-25188
·
IF 3.708
Meihua Wang,Weifen Niu,Xin Wu,Lixia Li,Jun Yang,Shaomin Shuang,Chuan Dong
3-Mercaptopropionic acid (MPA)-capped ZnS:Cu/ZnS core/shell quantum dots (QDs) have been synthesized via a facile aqueous coprecipitation method and characterized by fluorescence, UV-Vis absorption, infrared spectroscopy and transmission electron microscopy. The fluorescence of ZnS:Cu/ZnS could be increased in the presence of uric acid (UA). The affecting factors for the fluorescence of ZnS:Cu/ZnS were examined including pH, temperature and reacting time. Under the optimized conditions, the fluorescence intensity of the ZnS:Cu/ZnS QDs against the UA concentration showed a linear response in the range of 0.66 μM to 3.3 μM with the correlation coefficient (R2) 0.9973 and the limit of detection 0.044 μM. Most relevant molecules and physiological ions had no effect on the detection of UA. The feasibility of the developed method was further demonstrated by determining the concentration of uric acid in human urine samples and the recoveries were 95% ∼ 103%. Our work provides a sensitive, selective and convenient fluorescence method to determine UA in real samples.
研究领域:
分析化学
·
纳米医学
·
生物传感器
·
临床检验
·
分子诊断
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DOI
高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2014
·
IF 2.063
Jianhong Tan,Lei Guo,Shenying Xu
Corrosion inhibition of indole-3-carboxylic acid (ICA) on mild steel in 0.1 M H 2 SO 4 solution has been studied through weight loss, potentiodynamic polarization , electrochemical impedance spectroscopy (EIS), and scanning electron microscope (SEM) experiments. Plots from polarization and EIS techniques show ICA acts as a mixed type inhibitor and its high inhibition effectiveness is assumed to occur via the adsorption of the inhibitor molecules on steel surface. It is then found that this adsorption behavior obeys the Langmuir adsorption isotherm . Theoretical techniques incorporating molecular mechanics and molecular dynamics were used to simulate the adsorption of ICA molecule on Fe(1 1 0) surface.
研究领域:
材料科学
·
腐蚀科学
·
电化学
·
表面工程
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2020
·
IF 3.573
Yijiao Qiu,Houfang Lu,Yingming Zhu,Yingying Liu,Kejing Wu,Bin Liang
Phase-change solvents exhibit the promising potential to reduce the regeneration energy for CO2 capture. In this paper, 3-dimethylaminopropylamine (DMAPA) with intramolecular primary and tertiary amino groups was mixed with solvent NHD and water for phase-change absorption of CO2 in the model flue gas. The results show that the homogeneous mixture changes into two phases after CO2 absorption when NHD/H2O ranges from 9:1 to 5:5 and 90% of CO2 is enriched in the lower phase with only 23% of the total volume. The absorption loading reaches 1.06 mol CO2/mol amine, the phase separation time for DMAPA–NHD–H2O is only 14% of that for MEA–SA–H2O, and the viscosity of the lower phase is only 37.14 mPa·s when DMAPA and NHD/H2O are 1 M and 8:2, respectively. Analysis of the reaction mechanism shows that the primary amino group of DMAPA initially reacts with CO2 and the tertiary amino group captures proton of zwitterionic intermediate as an acceptor. The mixed-amine effect is suggested to explain the high absorption performance of the DMAPA–NHD–H2O mixture. The energy estimation shows that the regeneration energy is reduced by 42% compared with that of the 5 M MEA solution, which confirms the advantage of phase-change absorption using DMAPA–NHD–H2O.
研究领域:
化学工程
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环境科学
·
能源技术
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产品关联
DOI
高影响因子
LUMINESCENCE
·
2019
·Vol. 35
·期 2
·203-207
·
IF 1.691
Junfeng Qu,Han Jiang,Shuhong Xu,Chunlei Wang,Dayan Ban
The emission wavelength of organic–inorganic hybrid perovskite quantum dots (QDs) can be tuned by controlling reaction time relevant to the halide exchange. It is because halide exchange with different time would lead to different molar ratio of halides in perovskite QDs such as Cl and Br. Here, to research the ligand's effect on the halide exchange, this work synthesized 3-mercaptopropionic acid (MPA)-capped CH 3 NH 3 PbBr x Cl 3-x QDs. It was found that SH − of MPA appeared to inhibit the halide exchange during the reation. Moreover, although the MPA-capped CH 3 NH 3 PbBr x Cl 3-x QDs did not contain the chiral centre, they exhibit the optical rotation. This may provide a method for chirality manipulation of perovskite.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2013
·
IF 2.906
Jianxia Sun,Shun Bai,Weibin Bai,Feiyan Zou,Lei Zhang,Zhijian Su,Qihao Zhang,Shiyi Ou,Yadong Huang
3-Monochloropropane-1,2-diol (3-MCPD) is a well-known food processing contaminant that has been shown to impede the male reproductive function. However, its mechanism of action remains to be elucidated. In this study, the effects of 3-MCPD on progesterone production were investigated using R2C Leydig cells. 3-MCPD caused concentration-dependent inhibition of cell viability at the IC25, IC50, and IC75 levels of 1.027, 1.802, and 3.160 mM, respectively. Single cell gel/comet assay and atomic force microscopy assay showed that 3-MCPD significantly induced early apoptosis. In addition, 3-MCPD significantly reduced progesterone production by reducing the expression of cytochrome P450 side-chain cleavage enzyme, steroidogenic acute regulatory protein, and 3β-hydroxysteroid dehydrogenase in R2C cells. The change in steroidogenic acute regulatory protein expression was highly consistent with progesterone production. Furthermore, the mitochondrial membrane potential and cAMP significantly decreased.
研究领域:
毒理学
·
生殖生物学
·
细胞生物学
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DOI
PubMed
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 101
·98761-98767
·
IF 3.289
Liqun Ma,Shaobo Dong,Zijian He,Yulin Yang,Hongge Jia,Yutao Di,Yanan Tang,Yazhen Wang
In order to develop a new silane coupling agent that can be used as coupling agent and initiator, (3-(tert-butylperoxy)propyl)trimethoxysilane was synthesized by using tert-butyl hydroperoxide and (3-chloropropyl) trimethoxysilane. The new reagent was characterized by 1H-NMR, FT-IR and mass spectroscopy. The thermokinetics of the new reagent was investigated, including thermal stability, decomposition constants (Kd), activation energy (Ea), the heat of decomposition (ΔH) and pre-exponential factor (Ad). In addition, the application of (3-(tert-butylperoxy)propyl)trimethoxysilane on modificating nano-TiO2 and initiating polymerization was studied. The structures of the products of modificating nano-TiO2 and initiating polymerization were verified by XPS, FT-IR. The results indicated that the new reagent had the characteristics of a coupling agent and initiator.
研究领域:
材料化学
·
高分子科学
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产品关联
DOI
高影响因子
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
·
2025
·Vol. 116
·期 1
·9
·
IF 2.2
Huang Junyun,Liu Boying,Yuan Sijia,Zhou Haiyun,Bao Jian,Tu Yong,Wang Zunyao,Wang Weixia
Benzophenone-3 (BP-3), a widely used ultraviolet filter in personal care products, has been extensively detected in aquatic environments and poses potential ecological risks. This study innovatively investigated the pH-dependent acute toxicity of BP-3 to three model aquatic organisms— Daphnia magna , Photobacterium phosphoreum , and Danio rerio —by determining the EC 50 and LC 50 values across a pH range of 5.0 to 9.0. Our results revealed that BP-3 exerted greater acute toxicity on all three tested aquatic organisms under acidic conditions (pH 5.0) than under alkaline conditions (pH 9.0). The increased toxicity with lower pH was attributed to the predominance of the more lipophilic molecular form of BP-3, emphasizing the significant influence of environmental pH on BP-3 toxicity. These findings provide essential toxicological data for assessing the ecological risks of BP-3 in diverse aquatic environments, highlighting the necessity of considering BP-3 concentration, environmental pH and exposed species in ecological risk assessments.
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产品关联
DOI
PubMed
高影响因子
ChemistrySelect
·
2024
·Vol. 9
·期 3
·e202304182
·
IF 1.9
Yiguo He,Mengxiang Li,Liming Peng,Tong Yang,Dong Zhang,Yadong Zhang
Graphical Atorvastatin calcium is a pivotal pharmaceutical for the treatment of primary hypercholesterolemia, with the reaction between isobutyl acetate and aniline being a crucial step. By employing continuous flow synthesis technology, we achieved a yield of 94 % within a residence time of 15 minutes. Simultaneously, kinetic studies and CFD calculations were conducted. Subsequently, we conducted further reaction investigations and designed a continuous system. 4-methyl-3-oxo-n-phenyl-pentanamide, as a crucial component of atorvastatin calcium, often generates a large amount of by-products in conventional synthesis. Here, we first developed a continuous microflow system for the continuous flow synthesis of 4-methyl-3-oxo-n-phenyl-pentanamide. Compared to traditional batch reactors, the reaction time was reduced by 1/12 in the microreactor. Using this device, the kinetic parameters of the reaction were determined, and a reaction kinetics model was established to investigate the effects of channel geometry and material inlet velocity on the entire reaction system. Furthermore, we studied the subsequent reactions and successfully established a fully continuous synthesis device, where the two-step continuous flow chemical reactions were achieved at 40 minutes and a total yield of 32 %.
研究领域:
药物化学
·
有机合成
·
生物医学工程
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产品关联
DOI
高影响因子
Desalination and Water Treatment
·
2024
·
IF 1
Yuhang Xu,Wei Li,Sisi Qin,Kai Su,Junmin Chen,Shengli Zhang
ABSTRACT In this study, La(OH) 3 -loaded Juncus effusus (La-JE) with a three-dimensional structure was prepared via an in-situ precipitation and then wrapped in a cellulose membrane. The La-JE not only avoided the leakage of La(OH) 3 but also was separated from solution easily. The optimal pH for phosphate removal by the La-JE was 6. The removal rate of phosphate was positively correlated with adsorption time, La-JE dosage and reaction temperature, and negatively correlated with phosphate concentration. The adsorption process conformed to pseudo-second-order kinetic model and was better fit by Freundlich model. At 25°C, the maximum adsorption capacity of the La-JE was 22.75 mg·P/g. The influence of SO 4 2– , Cl – , NO 3 – , NH 4 + , HCO 3 – and CO 3 2– on phosphate removal was negligible, suggesting that the La-JE had good anti-interference ability. Mechanism analysis showed that the removal process of phosphate was related to both ligand exchange and surface precipitation. The application in real water environment exhibited that the La-JE had good potential for advanced dephosphorization of sewage treatment plant and natural waterbody remediation.
研究领域:
环境科学
·
水处理技术
✓ 已验证
DOI
高影响因子
POWDER TECHNOLOGY
·
2018
·
IF 3.23
Weiwei Chu,Zhenzhen Lu,Ruiqin Tan,Shihui Tang,Wei Xu,Weijie Song,Junhua Zhao
In this work, β-SrHPO 4 , Sr 3 (PO 4 ) 2 , and Sr 5 (PO 4 ) 3 (OH) (SrHAp) powders were successfully prepared by a controllable hydrothermal method and were utilized in removal of lead ion (Pb 2+ ). The effects of pH value, contact time and initial ion concentration on the immobilization of Pb 2+ were investigated systematically. Results showed that β-SrHPO 4 exhibited a capacity of 1438 ± 45 mg/g for Pb 2+ , while Sr 3 (PO 4 ) 2 and SrHAp showed values of 1223 ± 45 mg/g and 543 ± 45 mg/g respectively under the optimum conditions. The XRD , SEM and EDX results revealed that the mechanism of Pb 2+ immobilization by β-SrHPO 4 , Sr 3 (PO 4 ) 2 and SrHAp was mainly due to a process of dissolution and precipitation in the acidic solution. Comparing the immobilization behavior and capacities of β-SrHPO 4 , Sr 3 (PO 4 ) 2 and SrHAp for Pb 2+ removal, it is shown that β-SrHPO 4 is an effective and eco-friendly material for the removal of Pb 2+ from acidic aqueous solutions among strontium phosphates materials.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Foods
·
2024
·Vol. 13
·期 12
·1878
·
IF 4.7
Yushi Wei,Dan Zhang,Junhui Pan,Deming Gong,Guowen Zhang
Indole-3-propionic acid (IPA) is a plant growth regulator with good specificity and long action. IPA may be harmful to human health because of its accumulation in vegetables and fruits. Therefore, in this study, the properties of the interaction between calf thymus DNA (ctDNA) and IPA were systematically explored using multispectroscopic and computational modeling approaches. Analysis of fluorescence spectra showed that IPA binding to ctDNA to spontaneously form a complex was mainly driven by hydrogen bonds and hydrophobic interaction. DNA melting analysis, viscosity analysis, DNA cleavage study, and circular dichroism measurement revealed the groove binding of IPA to ctDNA and showed that the binding did not significantly change ctDNA confirmation. Furthermore, molecular docking found that IPA attached in the A-T rich minor groove region of the DNA. Molecular dynamics simulation showed that DNA and IPA formed a stable complex and IPA caused slight fluctuations for the residues at the binding site. Gel electrophoresis experiments showed that IPA did not significantly disrupt the DNA structure. These findings may provide useful information on the potential toxicological effects and environmental risk assessments of IPA residue in food at the molecular level.
研究领域:
生物化学
·
分子生物学
·
计算生物学
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DOI
PubMed
高影响因子
ECS Journal of Solid State Science and Technology
·
2015
·Vol. 4
·期 5
·M25
·
IF 1.558
Vantu Nguyen,Yueli Liu,Yang Li,Shah Abdul Hakim,Xue Yang,Wen Chen
Fe2(MoO4)3/carbon nanotubes (CNTs) nanocomposite was prepared by a precipitation method and used as a cathode for sodium-ion batteries (SIBs). The field emission scanning electron microscopy (FESEM) test showed that the CNTs and Fe2(MoO4)3 nanosheets formed an interpenetrating network structure. The X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that the Fe2(MoO4)3 was a monoclinic crystal structure and mixed with element states in the nanocomposite. The electrochemical properties of the Fe2(MoO4)3/CNTs nanocomposite were studies by electrochemical impedance spectroscopy (EIS) and galvanostatic charge-discharge measurement. The results indicated that Fe2(MoO4)3/CNTs nanocomposite had high specific capacity and good cycling stability as a cathode material for SIBs. As the charge/discharge curent density is at 1 C, the initial specific capacity of Fe2(MoO4)3/CNTs nanocomposite is 85 mAhg−1, and it remains 79.81 mAhg−1 after 50 cycles.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）