VACUUM
·
2024
·
IF 3.8
Zonghan Hu,Qi Wang,Zihang Wang,Lanlan Zhang,Chengwei Hu,Yuanhu Lei,Yupei Qiao,Bing Lv
Currently, the two predominant heterojunction types, namely type II and S-scheme heterojunctions, are extensively employed in photoelectrochemical (PEC) water splitting for hydrogen production. However, type II heterojunctions suffer from the drawback of diminished oxidation-reduction capability. In this work, S-scheme CdIn 2 S 4 /CuS (CIS/CuS) heterojunction nanoblocks (NBs) photoanode is constructed for the first time by a hydrothermal and the successive ionic layer adsorption and reaction (SILAR) methods. The heterojunction achieves a photocurrent density of up to 4.0 mA/cm 2 at 0 V vs. Ag/AgCl, 2.37 times that of the pure CIS NBs photoanode. X-ray photoelectron spectroscopy (XPS), Tauc plots, Mott-Schottky (M − S) tests and density functional theory (DFT) calculations reveal the formation of S-scheme band structure between the interface of CIS and CuS. As a result, the significantly enhanced PEC water splitting performance of CIS/CuS NBs photoanode is attributed to the superior light absorption ability of CuS and the effective charge separation achieved by S-scheme band structure between the interface of CIS and CuS. This work also provides new ideas and strategies for designing efficient S-scheme heterostructures for efficient PEC water splitting.
✓ 已验证
产品关联
DOI
高影响因子
Nano Energy
·
2025
·
IF 17.1
Qiaoyun Chen,Hatameh Asgarimoghaddam,Wenxi Ji,Wenting Wu,Ji Cao,Rui Wang,Wei Yu,Xiaoting Nie,Yi Zhou,Bo Song,Kevin P. Musselman
Although poly[bis(4-phenyl) (2,4,6-trimethylphenyl) amine] (PTAA) is a widely used hole transport layer (HTL) in perovskite solar cells, its poor conductivity and the mismatched energy levels between PTAA and formamidinium-based perovskites increase interfacial carrier recombination and charge-transport resistance. To solve these problems, inorganic CuS nanosheets were synthesized and applied as additives in PTAA for the first time. After the addition of CuS, the conductivity of the HTL improves, and the energy levels are better aligned. In addition, perovskite growth is controlled through the interaction between CuS and PbI 2 , thus improving the quality of the perovskite films, which reduces nonradiative recombination. The addition of CuS into PTAA improved the power conversion efficiency from 21.99 % to 22.92 %. Moreover, both the thermal and humidity stability improved.
✓ 已验证
产品关联
DOI
高影响因子
Foods
·
2024
·Vol. 13
·期 12
·1845
·
IF 4.7
Yiming Zhao,Baoshan He,Danyang Li,Leyan Gao,Wenjie Ren
In the realm of analysis, the lateral flow immunoassay (LFIA) is frequently utilized due to its capability to be fast and immediate. However, the biggest challenge of the LFIA is its low detection sensitivity and tolerance to matrix interference, making it impossible to enable accurate, qualitative analyses. In this study, we developed a new LFIA with higher affinity and sensitivity, based on a nanobody (G8-DIG) and CuS nanoflowers-Au (CuS NFs-Au), for the detection of aflatoxin B1(AFB1) in maize. We synthesized the immunoprobe G8-DIG@CuS NFs-Au, stimulated the in situ development of Au nanoparticles (Au NPs) on Cu NFs by electrical displacement, and obtained Cu NFs-Au for fixing the G8-DIG. G8-DIG@CuS NFs-Au probe-based LFIAs may, in ideal circumstances, use a strip chromatography reader to accomplish sensitive quantitative detection and qualitative visualization. AFB1has a detection range of 2.82–89.56 µg/L and a detection limit of 0.87 µg/L. When compared with an LFIA based on CuS NFs, this sensitivity is increased by 2.76 times. The practical application of this method in corn flour demonstrated a recovery rate of 81.7% to 117%. Therefore, CuS NFs-Au show great potential for detecting analytes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Lushuang Xu,Qinyue Chen,Yangwei Qian,Jin Wang,Chenxi Wang,Rui Fan,Jia-Wei Shen,Qiying Shen
Nanozymes provide therapeutic benefits against a diverse range of malignant tumors. However, their antitumor potencies are seriously impaired by their low catalytic efficiencies and the off-target toxicities caused by their “always-on” catalytic activity. Herein, we developed multifunctional nanoparticles co-loaded with ultra-small copper sulfide nanoparticles (CuS NPs) and disulfiram (DSF) (DSF/CuS@M). These nanoparticles had peroxidase-like activity and served as (near-infrared) NIR-activatable proenzymes to achieve synergistic in situ chemotherapy, chemodynamic therapy (CDT), photothermal therapy (PTT), and cuproptosis-based antitumor therapy. DSF/CuS@M not only provided PTT as NIR-activatable proenzymes but also enabled complete DSF and Cu 2+ release. Non-toxic DSF was converted into diethyldithiocarbamic acid (DDC) through a glutathione (GSH)-mediated metabolic reaction, leading to the generation of cytotoxic Cu(DDC) 2 in situ , which enhanced cell apoptosis. Cu 2+ was converted into Cu + by GSH, and this Cu + catalyzed the conversion of H 2 O 2 into hydroxyl radicals (·OH) to induce CDT. Moreover, Cu + could also bind to dihydrolipoyl transacetylase (DLAT) in the tricarboxylic acid (TCA) cycle, thereby inducing cuproptosis. These results demonstrate that the NIR-activatable proenzyme developed in this study is effective and safe for synergistic therapy against malignant tumors.
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 10
·4507-4520
·
IF 2.7
Luhua Wang,Yi Ren,Hongfang Zhao,Hongxia Li,Xiaohui Niu,Deyi Zhang,Haiyan Fan,Kunjie Wang
To address the water pollution problem caused by hexavalent chromium, this study took advantage of a multi-defect adsorption mechanism and constructed a multiple defect-containing type-II heterojunction material, CuS/Cv-CNNs. This material has simultaneous sulfur vacancies, copper vacancies, and carbon vacancies, which were used to accelerate the removal of chromium from wastewater. Attributed to the formation of electron-rich structures and free-moving ions by the construction of multiple defect sites, the photogenerated carriers generated by CuS/Cv-CNNs-70 were efficiently separated, and a high amount of physical Cr(VI) adsorption was achieved by electrostatic attraction and ion exchange, consistent with a Freundlich isothermal adsorption model. Studies on the adsorption thermodynamics demonstrate that CuS/Cv-CNNs-70 prefers to adsorb Cr(VI) when temperatures are raised. In addition, the removal of Cr(VI) (120 mg L−1) by CuS/Cv-CNNs-70 reached 97.10% after 60 minutes through the synergistic effect of adsorption and visible-light photocatalysis. This finding indicates that the synergistic effect between the multilocation defects stimulated the combined potential of adsorption and photocatalysis of CuS/Cv-CNNs-70 to realize the full utilization of the defects. In conclusion, this study confirms the prominent role of a multiple defect mechanism in wastewater treatment and environmental protection.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Water Process Engineering
·
2024
·
IF 6.3
Meng Li,Weiji Sun,Wangkai Hui,Lang Liu
Photocatalytic oxidation technology is a green and low carbon approach for degradation of mineral processing wastewater, which is extensively applied to ecological environment restoration. In this research, coal gangue-ZnS/CuS pyroelectric/photothermal composite photocatalyst is constructed by high temperature calcination method. The temperature difference between heat converted from light energy absorbed by CuS and the circulating condensate water provides the impelling force for the pyroelectric effect. The porous structure of coal gangue acts as a “heat capacitor”, which furnishes greater temperature fluctuation for pyroelectric effect. Furthermore, the hydroxyl groups on the surface of coal gangue can availably adsorb oxygen and facilely form superoxide radicals with electrons. The degradation efficiency of xanthate is as high as 99.5 % within 50 min. This research has significant implications for designing and developing highly efficient photocatalysts for the degradation of mining wastewater.
✓ 已验证
产品关联
DOI
高影响因子
ACS Nano
·
2024
·
IF 15.8
Xiaoyu Chen,Ning Huang,Danyang Wang,Miao Zhang,Xuyang Deng,Fangze Guo,Bingcheng Yi,Changqing Yuan,Qihui Zhou
Periodontitis, a prevalent chronic inflammatory disease worldwide, is triggered by periodontopathogenic bacteria, resulting in the progressive destruction of periodontal tissue, particularly the alveolar bone. To effectively address periodontitis, this study proposed a nanoformulation known as CuS@MSN-SCS. This formulation involves coating citrate-grafted copper sulfide (CuS) nanoparticles with mesoporous silica (MSNs), followed by surface modification using amino groups and sulfated chitosan (SCS) through electrostatic interactions. The objective of this formulation is to achieve efficient bacteria removal by inducing ROS signaling pathways mediated by Cu2+ ions. Additionally, it aims to promote alveolar bone regeneration through Cu2+-induced pro-angiogenesis and SCS-mediated bone regeneration. As anticipated, by regulating the surface charges, the negatively charged CuS nanoparticles capped with sodium citrate were successfully coated with MSNs, and the subsequent introduction of amine groups using (3-aminopropyl)triethoxysilane was followed by the incorporation of SCS through electrostatic interactions, resulting in the formation of CuS@MSN-SCS. The developed nanoformulation was verified to not only significantly exacerbate the oxidative stress of Fusobacterium nucleatum, thereby suppressing bacteria growth and biofilm formation in vitro, but also effectively alleviate the inflammatory response and promote alveolar bone regeneration without evident biotoxicity in an in vivo rat periodontitis model. These findings contribute to the therapeutic effect on periodontitis. Overall, this study successfully developed a nanoformulation for combating bacteria and facilitating alveolar bone regeneration, demonstrating the promising potential for clinical treatment of periodontitis.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Chemistry
·
2025
·
IF 6.7
Shan Zhang,Meng-chen Xu,Yu-peng Lu,Yi-tong Jiang,Shuo-chao You,Ya-hao Geng,Xiao-yan Li,Gui-yong Xiao
Biomedical dressings are highly susceptible to bacterial infections, and most suffer from poor mechanical resistance, leading to structural damage during application and reduced effectiveness. Therefore, developing novel dressings with high mechanical strength and effective antibacterial ability is essential. In this study, a multi-component composite membrane is designed to address these challenges by leveraging the reinforcing effect of hydroxyapatite nanofibers (HANFs) and the photothermal antibacterial abilities of copper sulfide (CuS). This composite membrane exhibits excellent mechanical properties, with a maximum ultimate tensile strength and Young's modulus of 61 ± 1.25 MPa and 937.36 ± 16.15 MPa, respectively, in the dry state. Under near infrared (NIR) irradiation, the generated heat and released Cu 2+ produce a synergistic antibacterial effect, with the inhibition rate against Staphylococcus aureus ( S. aureus ) exceeding 90 % when the HANFs@CuS content reaches 40 wt%. Cellular experiments confirm the good biocompatibility of the composite membranes across different HANFs@CuS contents, with cell viability maintaining over 80 % at 40 wt%. This study seamlessly integrates the mechanical advantage of HANFs with the photothermal antibacterial ability of CuS nanoparticles , providing a promising strategy for designing advanced biomedical dressings.
✓ 已验证
产品关联
DOI
高影响因子
CELLULOSE
·
2025
·
IF 4.8
Sun Yanyan,Natsuki Jun,Zhou Wanyu,Zou Lihua,Wang Zhen,Li Bingbing,Gao Yamin,Chu Changliu,Natsuki Toshiaki
Wearable electronics have gained considerable attention in recent years owing to their softness, flexibility, and compatibility with the human body. However, most conventional multifunctional smart textiles are developed by integrating various fibers or fabrics with single functionalities, facing challenges such as high integration complexity and poor stability, and struggling to meet the demands of wearable electronics. In this study, we present a simple and scalable method involving dip-coating and spray-coating to produce multifunctional, wearable, high-performance MXene/CuS/cotton fabrics. Leveraging the conductive networks formed by synergistic MXene/CuS and the porous structure of the fabrics, these MXene/CuS/cotton fabrics demonstrate impressive electromagnetic interference (EMI) shielding effectiveness (51.1 dB at a thickness of 335 μm) and notable Joule heating performance (approximately 60 °C at a voltage of 6 V). Moreover, when pressure is applied, MXene/CuS/cotton fabrics exhibit negative piezoresistivity, high sensitivity (− 18.2 kPa −1 for 1–4 kPa pressures), rapid response and recovery times (0.4 s), along with exceptional long-term durability and stability (over 2000 cycles). These remarkable properties suggest that MXene/CuS/cotton fabrics are highly promising for future applications in human motion detection, EMI shielding, thermal management, and other applications.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Jinqiu Xu,Haoyu Chen,Jing Liu,Jianru Tang,Xiaohua Zhu,Sheng Yang,Shu Huang,Youyu Zhang,Meiling Liu
The development of analytical methods capable of simultaneously detecting multiple components in biological samples holds significant potential for advancing disease diagnosis. However, constructing optical platforms for continuous detection remains challenging due to limitations such as insufficient selectivity, specificity, response speed, and sensitivity. Herein, we developed a facile and efficient microwave-assisted method to rapidly synthesize CuS quantum dots (QDs) and constructed a fluorescence-based sensing platform for detecting Ag + and glutathione (GSH). The fluorescence emission of CuS QDs at 500 nm was selectively quenched upon interaction with Ag + , exhibiting a linear correlation with Ag + concentrations ranging from 0.3 to 300 μM. Notably, the quenched fluorescence could be restored by introducing GSH, accompanied by a slight redshift in the emission wavelength. This Ag + -mediated “off-on” fluorescence sensing mechanism significantly enhanced the sensitivity for GSH detection. This platform demonstrated high selectivity towards both Ag + and GSH, enabling their quantitative determination in complex matrices, including tap water, human serum, and cell lysate. This work not only presents a novel synthetic approach for CuS QDs but also achieves successive detection of Ag + and GSH without requiring complex probe modifications or the integration of multiple nanomaterials, representing a simplified yet highly effective design compared to more intricate systems. The proposed platform serves as a versatile measurement tool applicable across various fields, from environmental contaminant monitoring to the detection of key biological thiols, demonstrating a generalizable strategy for diverse analytical scenarios in both environmental and clinical contexts.
研究领域:
分析化学
·
纳米生物学
·
生物医学工程
·
分子诊断
·
环境监测
·
临床检验
·
药物代谢
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19
Dong Wang,Feng Yuan,Xuliang Deng,Haoyang Li,Siyang Nie,Qingda Liu,Xun Wang
Therapy based on heat and reactive oxygen species (ROS) generation have attracted increasing attention, while the weak photothermal ability and low ROS production have severely limited the efficiency of the tumor treatment. Here, 2D ultrathin CuS-phosphomolybdic acid (PMA) nanosheets are synthesized at sub-nanoscale. Typically, the improved second near-infrared light (NIR-II) light absorption, small bandgap, fast hot carrier response, abundant oxygen vacancies, and the electron delocalization between closely connected PMA and CuS units in sub-nanoscale result in the notably enhanced NIR-II photothermal therapy (PTT) performance of CuS-PMA. The reversible redox of Mo active sites in PMA provides basis for glutathione (GSH) depletion while triggering chemodynamic therapy (CDT) in the tumor microenvironment (TME), and the heat produced by the PTT greatly promotes the CDT and GSH depletion, where CuS-PMA presents sevenfold more ROS generation and fourfold more GSH depletion under PTT. In addition, the ROS generation/GSH depletion can downregulate heat shock proteins, weakening the heat resistance of tumor cells and thereby amplifying the killing effect of PTT. Moreover, the combination of antiprogrammed death-ligand 1 (αPD-L1) with the treatment of CuS-PMA promote the immunotherapy, resulting in the suppression of untreated abscopal tumors.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Qingao Wang,Shang Tang,Fangze Guo,Yunqi Feng,Yabo Li,Mengqing Gong,Yu Zhang,Caiyi Zhang,Li Mei,Youbin Wang,Daishuo Zhang,Wen Su,Changqing Yuan
Periodontitis is a chronic infectious disease caused by bacteria, characterized by progressive destruction of periodontal soft and hard tissues, ultimately leading to tooth loss. To treat periodontitis, this study combined the advantages of nanoparticles and hydrogels, and successfully developed an injectable aldehyde-functionalized PF127, carboxymethyl and sulfonated chitosan hydrogel doped with copper sulfide nanoparticles (CuS/PCS). The CuS/PCS hydrogel was synthesized through a dynamic Schiff base reaction. The injectable hydrogel forms a gel in situ after injection into deep periodontal pockets, achieving high antibacterial activity without causing bacterial resistance. The CuS/PCS hydrogel exhibited good biocompatibility, maintained cell viability, promoted stem cell proliferation, and demonstrated significant antimicrobial activity. In the rat periodontitis model, the CuS/PCS hydrogel effectively reduced inflammation and bone loss, and promoted periodontal tissue regeneration. These results suggest that CuS/PCS hydrogel could be a promising biomaterial for the treatment of periodontitis.
研究领域:
生物材料学
·
口腔医学
·
纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）