RARE METALS
·
2024
·
IF 9.6
Li Hang,Wang Fei,Sun Xiao-Jing,Qi Liu-Jie,Li Jing-An,Iqbal Mujahid,Guan Shao-Kang
Ischemic stroke is increasing worldwide, and stent intervention has gradually become one of the effective treatments. Owing to its good mechanical properties and biocompatibility, biodegradable Mg-Zn-Y-Nd alloy (ZE21B) has good application prospects in vascular stents. However, too fast degradation and delayed endothelialization are the bottleneck problem to limit its further application. In this study, the bio-inspired coating barnacle cement cp19k is constructed on ZE21B surface through electrostatic spraying to improve the corrosion resistance and pro-endothelialization ability. The coating was evaluated through electrochemistry, static immersion corrosion, in vitro blood experiments and cell experiments. Cp19k effectively improved the corrosion resistance of the substrate ZE21B, reduced the degradation rate, improved endothelial cell proliferation and migration capabilities, inhibited smooth muscle cells proliferation and regulated contractile phenotype, inhibited macrophage adhesion, regulated macrophage M2 phenotype, and reduced the expression of inflammatory factor of TNF-α and inhibited fibroplasia in vivo. Our data indicated that the barnacle cement cp19k coating had potential application on the surface modification of Mg alloy cerebrovascular stent. Graphical abstract
研究领域:
生物医学工程
·
材料科学
·
血管生物学
·
神经学
✓ 已验证
DOI
高影响因子
ULTRASONICS SONOCHEMISTRY
·
2024
·
IF 8.7
Qi Zhang,Yifei Zhu,Guofeng Zhang,Honghui Xue,Bo Ding,Juan Tu,Dong Zhang,Xiasheng Guo
Acoustic cavitation plays a critical role in various biomedical applications. However, uncontrolled cavitation can lead to undesired damage to healthy tissues. Therefore, real-time monitoring and quantitative evaluation of cavitation dynamics is essential for understanding underlying mechanisms and optimizing ultrasound treatment efficiency and safety. The current research addressed the limitations of traditionally used cavitation detection methods by developing introduced an adaptive time-division multiplexing passive cavitation imaging (PCI) system integrated into a commercial diagnostic ultrasound platform. This new method combined real-time cavitation monitoring with B-mode imaging, allowing for simultaneous visualization of treatment progress and 2D quantitative evaluation of cavitation dosage within targeted area. An improved delay-and-sum (DAS) algorithm, optimized with a minimum variance (MV) beamformer, is utilized to minimize the side lobe effect and improve the axial resolution typically associated with PCI. In additional to visualize and quantitatively assess the cavitation activities generated under varied acoustic pressures and microbubble concentrations, this system was specifically applied to perform 2D cavitation evaluation for ultrasound thrombolysis mediated by different solutions, e.g. , saline, nanodiamond (ND) and nitrogen-annealed nanodiamond (N-AND). This research aims to bridge the gap between laboratory-based research systems and real-time spatiotemporal cavitation evaluation demands in practical uses. Results indicate that this improved 2D cavitation monitoring and evaluation system could offer a useful tool for comprehensive evaluating cavitation-mediated effects ( e.g. , ultrasound thrombolysis), providing valuable insights into in-depth understanding of cavitation mechanisms and optimization of cavitation applications.
研究领域:
生物医学工程
·
超声治疗
·
医学成像
·
空化动力学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2023
·Vol. 14
·期 1
·1-10
·
IF 16.6
Jiang Zhao,He Liangrui,Yang Zhiwen,Qiu Huibin,Chen Xiaoyuan,Yu Xujiang,Li Wanwan
Distinctive upconversion or downshifting of lanthanide nanocrystals holds promise for biomedical and photonic applications. However, either process requires high-energy lasers at discrete wavelengths for excitation. Here we demonstrate that co-sensitization can break this limitation with ultrawide excitation bands. We achieve co-sensitization by employing Nd 3+ and Ho 3+ as the co-sensitizers with complementary absorptions from the ultraviolet to infrared region. Symmetric penta-layer core-shell nanostructure enables tunable fluorescence in the visible and the second near-infrared window when incorporating different activators (Er 3+ , Ho 3+ , Pr 3+ , and Tm 3+ ). Transient spectra confirm the directional energy transfer from sensitizers to activators through the bridge of Yb 3+ . We validate the features of the nanocrystals for low-powered white light-emitting diode-mediated whole-body angiography of mice with a signal-to-noise ratio of 12.3 and excitation-regulated encryption. This co-sensitization strategy paves a new way in lanthanide nanocrystals for multidirectional photon conversion manipulation and excitation-bandwidth-regulated fluorescence applications.
研究领域:
纳米技术
·
生物光子学
·
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2012
·
IF 4.601
Wenlong Yin,Wendong Wang,Lei Bai,Kai Feng,Youguo Shi,Wenyu Hao,Jiyong Yao,Yicheng Wu
The 12 new rare-earth tellurides Ba2MLnTe5 (M = Ga and Ln = Sm, Gd, Dy, Er, Y; M = In and Ln = Ce, Nd, Sm, Gd, Dy, Er, Y) have been synthesized by solid-state reactions. The two compounds Ba2GaLnTe5 (Ln = Sm, Gd) are isostructural and crystallize in the centrosymmetric space group P1̅, while the other 10 compounds belong to another structure type in the noncentrosymmetric space group Cmc21. In both structure types, there are one-dimensional anionic 1∞[MLnTe5]4– chains built from LnTe6 octahedra and MTe4 (M = Ga, In) tetrahedra, but the connectivity between the LnTe6 octahedra and MTe4 tetrahedra is different for the two structure types. On the basis of the diffuse-reflectance spectra, the band gaps are around 1.1–1.3 eV for these compounds. The Ba2MLnTe5 (M = Ga and Ln = Gd, Dy; M = In and Ln = Gd, Dy, Er) compounds are paramagnetic and obey the Curie–Weiss law, while the magnetic susceptibility of Ba2InSmTe5 deviates from the Curie–Weiss law. In addition, electronic structure calculation on Ba2MYTe5 (M = Ga, In) indicates that they are both direct-gap semiconductors with large nonlinear-optical coefficients.
研究领域:
材料科学
·
凝聚态物理
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2013
·Vol. 97
·期 3
·990-995
·
IF 2.107
Kuo Jiang,Songbai Liu,Yuan Li,Yaofei Li
Powders of zirconia doped with 8 mol% REO 1.5 (RE = Yb, Y, Gd, and Nd) were synthesized by using the sol–spray pyrolysis method. The effects of RE 3+ ionic radius on monoclinic (m) phase content of powders were investigated. The XRD results showed that the metastable tetragonal (t′) phase underwent a complete phase change to form m and cubic (c) phases after a heat treatment of 50–100 h at 1450°C. A cation size-dependent reduction in the m phase content of the REO 1.5 partially stabilized ZrO 2 powders was observed. The SEM–EDS analysis of the powders revealed that the RE 3+ concentrations in the c phases decreased with decreasing the RE 3+ ionic radius. These results indicate that the stabilizer concentration of the c phase can be attributed to RE 3+ ionic radii, resulting in different m phase contents. Compared to the REO 1.5 single doped ZrO 2 , the m phase contents of 8 mol% (RE 0.5 Yb 0.5 )–ZrO 2 (RE = Y, Gd, and Nd) powders were significantly reduced. The results prove that the stabilizer with a lower RE 3+ size is effective in reducing the m phase content of partially stabilized ZrO 2 after annealing at high temperatures.
研究领域:
材料科学
·
陶瓷学
✓ 已验证
DOI
高影响因子
Bioactive Materials
·
2021
·
IF 14.593
Meiqi Chang,Wei Feng,Li Ding,Hongguang Zhang,Caihong Dong,Yu Chen,Jianlin Shi
Tumor oxygenation level has been regarded as an attractive target to elevate the efficiency of photodynamic therapy (PDT). Cyanobacterial photosynthesis-mediated reversal of tumor hypoxia could enable an oxygen-boosted PDT, but is limited by scant penetration depth and efficiency of external light. Herein, aiming at the dual purposes of reducing biological toxicity induced by long-term light irradiation and alleviating hypoxia, we here introduce a novel-designed CaAl 2 O 4 :Eu,Nd blue persistent luminescence material (PLM) as the in vivo light source after pre-excited in vitro . The ingenious construction of blue-emitting PLM with “optical battery” characteristics activates cyanobacterial cells and verteporfin simultaneously, which performs the successive oxygen supply and singlet oxygen generation without the long-term external excitation, resulting in the modulated tumor hypoxic microenvironment and enhanced photodynamic tumor proliferation inhibition efficiency. Both in vitro cellular assessment and in vivo tumor evaluation results affirm the advantages of self-produced oxygen PDT system and evidence the notable antineoplastic outcome. This work develops an irradiation-free photosynthetic bacteria-based PDT platform for the optimization of both oxygen production capacity and light utilization efficiency in cancer treatment, which is expected to promote the clinical progress of microbial-based photonic therapy.
研究领域:
癌症治疗
·
生物光子学
·
材料科学
·
生物工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CRYSTENGCOMM
·
2020
·Vol. 22
·期 38
·6330-6338
·
IF 3.117
Chunyan Cheng,Yueshan Xu,Gejihu De,Jianxun Wang,Wei Wu,Yuexing Tian,Shasha Wang
Rare-earth doped upconversion nanoparticles (UCNPs) have attracted wide-ranging interest due to their potential applications in bioimaging and biolabeling, where a high emission intensity and small particle size are needed. However, common synthesis processes can be somewhat complex or require additional reactants, and the use of small-size NPs is limited by their weak luminescence intensity. In this work, uniform, monodisperse ∼5 nm β-NaGdF4:20% Yb/2% Er NPs were synthesized via a simple one-pot synthesis method in the high boiling-point solvents 1-octadecene (ODE) and oleic acid (OA) using a single dose of NaF at an ultralow NaF concentration of NaF/RE = 4. The effects of NaF/RE, the reaction temperature, and the reaction time on the size and phase of the particles were investigated. High-quality β-NaGdF4:20% Yb/2% Er@β-NaGdF4:20% Yb/10% Nd core–shell NPs with a size of ∼13 nm, enhanced UC luminescence, long UC lifetimes (τ) for green (τ ≈ 150 μs) and red (τ ≈ 105 μs) emission under 980 and 808 nm excitation, revealed via lifetime imaging, and obvious emission in the near-infrared (NIR) II region were synthesized. The synthesized core–shell NPs may result in a decrease in the overheating effect and allow for a deep penetration depth when further used for bioimaging applications. This work could inspire the synthesis of other high-quality RE-doped UCNPs via adding a single dose of a small amount of NaF and could lay the foundation for the use of Gd-based UCNPs in biomedical applications.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLUTION CHEMISTRY
·
2011
·Vol. 40
·期 8
·1447-1457
·
IF 1.335
Hu Yu-Feng,Jin Chuan-Wei,Zhang Jin-Zhu,Ling Shan
Electrical conductivities were measured for the ternary systems Y(NO 3 ) 3 +La(NO 3 ) 3 +H 2 O, La(NO 3 ) 3 +Ce(NO 3 ) 3 +H 2 O, La(NO 3 ) 3 +Nd(NO 3 ) 3 +H 2 O, and their binary subsystems Y(NO 3 ) 3 +H 2 O, La(NO 3 ) 3 +H 2 O, Ce(NO 3 ) 3 +H 2 O, and Nd(NO 3 ) 3 +H 2 O at (293.15, 298.15 and 308.15) K. The measured conductivities were used to test the generalized Young’s rule and the semi-ideal solution theory. The comparison results show that the generalized Young’s rule and the semi-ideal solution theory can yield good predictions for the conductivities of the ternary electrolyte solutions, implying that the conductivities of aqueous solutions of (1:3 + 1:3) electrolyte mixtures can be well predicted from those of their constituent binary solutions by the simple equations.
研究领域:
物理化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2011
·
IF 2.089
Yu-Feng Hu,Chuan-Wei Jin,Shan Ling,Jin-Zhu Zhang
Densities were measured for the ternary systems Y(NO3)3 + La(NO3)3 + H2O, La(NO3)3 + Ce(NO3)3 + H2O, and La(NO3)3 + Nd(NO3)3 + H2O and their binary subsystems at (293.15, 298.15, and 308.15) K. The results were used to test the applicability of simple equations for the density of the mixed solutions. The predictions of the simple equations agree well with measured values, indicating that the densities of the examined electrolyte solutions can be well predicted from those of their constituent binary solutions by the simple equations.
研究领域:
化学
·
物理化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Xuyi Wei,Xiaohui Mao,Junwei Han,Wenqing Qin,Hongbo Zeng
Efficient recovery of rare earth elements (REEs) from wastewater is crucial for advancing resource utilization and environmental protection. Herein, a novel nitrogen-rich hydrogel adsorbent (PEI-ALG@KLN) was synthesized by modifying coated kaolinite-alginate composite hydrogels with polyethylenimine through polyelectrolyte interactions and Schiff’s base reaction. Various characterizations revealed that the high selective adsorption capacity of Ho (155 mg/g) and Nd (125 mg/g) on PEI-ALG@KLN is due to a combination of REEs (Lewis acids) via coordination interactions with nitrogen-containing functional groups (Lewis bases) and electrostatic interactions; its adsorption capacity remains more than 85 % after five adsorption-desorption cycles. In waste NdFeB magnet hydrometallurgical wastewater, the recovery rate of PEI-ALG@KLN for Nd and Dy can reach more than 93 %, whereas that of Fe is only 5.04 %. Machine learning prediction was used to evaluate adsorbent properties via different predictive models, with the random forest (RF) model showing superior predictive accuracy. The order of significance for adsorption capacity was pH > time > initial concentration > electronegativity > ion radius, as indicated by the RF model feature importance analysis and SHapley Additive exPlanations values. These results confirm that PEI-ALG@KLN has considerable potential in the selective extraction of REEs from wastewater.
研究领域:
环境科学
·
材料科学
·
化学工程
·
废物管理
·
机器学习
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-8
·
IF 14.7
Zhou Mengwei,Huang Ping,Shang Xiaoying,Zhang Ruihuan,Zhang Wen,Shao Zhiqing,Zhang Shuo,Zheng Wei,Chen Xueyuan
Photon upconversion through lanthanide-doped nanoparticles is of great significance for various applications. However, the current development of upconversion nanoparticles is hindered by the low quantum efficiency and long radiative lifetimes of lanthanide ions, restricting their applications in time-dependent nanophotonics. Herein, we report ultrafast upconversion superfluorescence with a lifetime of sub-2.5 ns in lanthanide-doped nanoparticles at room temperature. Upon excitation with an 800-nm fs-pulsed laser, we achieve a large number ( N = 912) of correlated dipoles in Nd 3+ -concentrated nanoparticles, resulting in collective coherent emission with two orders of magnitude amplification in intensity and more than three orders of magnitude improvement in the radiative decay rate. Furthermore, we demonstrate that the control of excitation power and emitting sample length enables the lifetime manipulation of upconversion emission in a wide range from μs to sub-ns, accompanied by the typical superfluorescence signature of Burnham-Chiao ringing. These findings may benefit applications in many advanced technologies such as quantum counting and high-speed super-resolution bioimaging.
研究领域:
纳米技术
·
光子学
·
材料科学
·
光学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
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