JOURNAL OF HAZARDOUS MATERIALS
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2021
·
IF 10.588
Shuaibing Guo,Bing Yu,Adeel Ahmed,Hailin Cong,Youqing Shen
Emerging infectious diseases caused by the spread of bacteria and viruses are a major burden on global economic development and public health. At present, most personal protective equipment has weak antibacterial and anti-viral properties. The PAN/PTHP nanofibers reported in this article provide a new method for the development of personal protective equipment. In this study, a mixture of PTHP and PAN was prepared into PAN/PTHP nanofibers with high-efficiency and long-lasting antibacterial effects (>99.999%) through the electrospinning process. Live/dead staining and cell proliferation experiments showed that the preparation of PAN/PTHP nanofibers has good cell compatibility. In addition, PAN/PTHP nanofibers show obvious destructive effects on lentiviruses. Based on these characteristics, PAN/PTHP nanofibers were applied to facial masks, which can be used as the inflatable biocidal layer of facial masks and have an excellent interception effect on particles in the air. The successful synthesis of these fascinating materials may provide new insights for the development of new protective materials.
研究领域:
材料科学
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生物医学工程
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纳米技术
·
公共卫生
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Qiu-hui Hu,De-yu Tang,Xing-han Wang,Ling-ling Yan,Luo-lin Deng,Mei-qi Zhao,Er-ning Deng,Qing-han Zhou
Organic pollutants and microorganisms have become the main challenge in sewage treatment for decades. This mainly results from rapidly developing industry and urbanisation. However, simultaneous clearance of the organic pollutants and microorganisms in water still remains challenging in wastewater treatment. To address this problem, a novel molecularly imprinted metal–organic framework (MOF)/polyacrylonitrile (PAN) hybrid nanofibrous membrane (MOF/PAN-MIM) was prepared for selectively adsorbing bisphenol A (BPA) and inhibiting bacterial fouling in water treatment. Based on the experimental results, the MOF/PAN-MIM showed higher affinity towards BPA as compared to any other organic pollutants and a selective adsorption order of BPA > bisphenol F (BPF) > bisphenol S (BPS) > phenol > nitrophenol > resorcinol with adsorption performance 56.63 mg·g −1 . The kinetics and isotherm models of the adsorption of MOF/PAN-MIM towards BPA are best fitted to a pseudo-second-order mode and a Langmuir isotherm. The cyclic reusability of the membranes was demonstrated by the regeneration experiments, with a removal efficiency of 77.73% towards BPA and a negligible Cu ion leakage of 0.64% after six adsorption–desorption cycles. Additionally, the inhibition rate against E. coli and S. aureus was measured to be greater than 90% via the antibacterial assay. The above results indicated that the as-prepared MOF/PAN hybrid nanofibrous membrane has efficient selectivity, sustained cyclic adsorption ability, and antibacterial fouling effect, which can be used as a potential multi-functional filtration membrane in real wastewater treatment.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
POLYMER
·
2025
·
IF 4.5
Yi Chen,Xuan Wang,Hongyang Ma,Shyam Venkateswaran,Benjamin S. Hsiao
Chiral electrospun fibrous membranes with nanoscale fiber diameter were fabricated from synthetic polymers, poly(L-(-)-menthyl methacrylate) and poly(D-(+)-menthyl methacrylate), respectively, and employed as chiral filters for highly selective separation of chiral compounds. The structure and morphology of chiral nanofibrous membranes were controlled by adjusting the molecular weight of the polymer, the solution concentration, and the composition of solvents, verified with SEM measurements. To enhance the mechanical properties of a chiral nanofibrous membrane, polyacrylonitrile (PAN) was employed as second nanofibrous component serving as a skeleton, where a chiral nanofibrous composite membrane was fabricated through a two-nozzle electrospinning approach. Chiral compounds (S)-(-)-α- and (R)-(+)-α-phenethylamine were employed to challenge the separation efficiency of PAN/L-PMnMA and PAN/D-PMnMA nanofibrous composite membranes, in terms of the selective adsorption capability, while high selective factor was achieved for chiral isomers, implying that the chiral nanofibrous composite membrane could be potentially used for the chiral separation of natural products.
研究领域:
材料科学
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高分子科学
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分析化学
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纳米技术
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分离科学
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产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Jiaxin Lin,Jingqi Chen,Minghao Li,Dan Li,Zheye Zhang,Peng Chen,Weiqing Zhang
Reactive oxygen species (ROS) are central regulators of redox homeostasis and cell fate. However, their precise orchestration to trigger PANoptosis, a coordinated form of programmed cell death (PCD) integrating pyroptosis, apoptosis, and necroptosis, remains underexplored. Herein, we report a gold single-atom nanozyme (Au-SA/NHC) featuring atomically dispersed Au N 4 sites that enable energy-independent, parallel and cascaded ROS generation. By mimicking peroxidase (POD), catalase (CAT), and glutathione oxidase (GSH-OXD) activities, Au-SA/NHC sustainably produces singlet oxygen ( 1 O 2 ) and hydroxyl radicals (∙OH) from endogenous substrates while depleting glutathione (GSH) to amplify oxidative stress. This redox remodeling triggers mitochondrial dysfunction, which acts as a central hub to bridge ROS stress with the assembly of the PANoptosome and activation of downstream signaling. Pharmacological and redox interventions—including ROS scavenging, mitochondrial protection, and inhibition of individual death modules—validated this axis and confirmed that PANoptosis represents the predominant cell death mode induced by Au-SA/NHC. In vivo, Au-SA/NHC significantly suppressed tumor growth with favorable biocompatibility, whereas ROS scavenging abolished therapeutic efficacy, underscoring the essential role of oxidative stress. Collectively, this work establishes a redox-engineered single-atom nanozyme as a next-generation catalytic nanotherapy capable of precisely engaging coordinated cell death programs through the ROS–mitochondria–PANoptosis axis.
研究领域:
肿瘤学
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纳米医学
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细胞死亡机制
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氧化还原生物学
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分子生物学
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转化医学
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生物材料
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Fangfang Wei,Feng Qi,Yangyang Li,Weiyu Dou,Tangye Zeng,Jing Wang,Zhikan Yao,Lin Zhang,Zhe Tang
Bilirubin is a serious toxin in the blood of liver failure patients, and the development of bilirubin adsorbent with high removal efficiency, excellent hemocompatibility is crucial to improve the efficacy of hemoperfusion therapy. Herein, PAN/PEI nanofiber membrane (NFM) with amino-rich and smooth surface structure was prepared through a more facile co-blended electrospun method. During simulated adsorption experiments in vitro , PAN/PEI NFMs exhibited a high adsorption capacity of 142.79 mg g −1 for free bilirubin at clinical bilirubin concentration (100 mg L -1 ) in patients with liver failure. In addition, the bilirubin removal efficiency in static adsorption exceeded 96% when the PAN/PEI NFMs addition was greater than 120 mg. In particular, PAN/PEI NFMs displayed excellent hemocompatibility, presented a low hemolysis rate (0.4%), favorable anti-adhesion properties for hemocyte and plasma protein, and had no significant effect on coagulation. The development of this facile method promotes the feasibility of nanofibrous membranes for the treatment of hyperbilirubinemia with significant implications for improving therapeutic efficacy.
研究领域:
材料科学
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生物医学工程
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血液透析
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Feng Li,Huijie Lv,Feng Zhu,Qiuping Zhang,Qian Xu,Wenliang Ji
Co-extraction of multiple types of target substances is the key to achieve high throughput detection. In this work, PDA@MOF-808/PAN NFsM was prepared by co -modified polyacrylonitrile nanofiber membrane (PAN NFsM) with polydopamine (PDA) and metal-organic framework-808 (MOF-808), and its potential as a solid-phase extraction (SPE) adsorbent was investigated by using the most typical nine veterinary drug residues in eggs and chicken as model target substances. The results show that PDA@MOF-808/PAN NFsM could effectively co-extract all the target substances (adsorption efficiency ranged from 81.46 % to 96.78 %), and had good capability of sample matrix purification (matrix effect was lower than −15.26 %), so a new SPE method has been established. Combined with UPLC-MS/MS, the detection limits were 0.3 to 3.1 μg/kg, the recoveries were between 71.02 % and 106.48 %, and the relative standard deviations were lower than 12.03 %, indicating that the method has considerable good sensitivity, accuracy and precision.
研究领域:
分析化学
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兽医学
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食品安全
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Xiangxiang Liu,Bingyin Jiang,Xing Yin,Hongyang Ma,Benjamin S. Hsiao
Nanofibrous composite membranes using polyvinyl alcohol (PVA) and polyacrylonitrile (PAN) were fabricated by the two-nozzle electrospinning approach, where the PAN nanofibrous component was modified selectively, and the composite membranes were employed for removal of both nanoparticles and heavy metal ions such as chromium (VI) and cadmium (II) from contaminated water. The chemical compositions and morphologies of the membranes were determined by FTIR, TGA, elemental analysis, SEM, and porometer measurements. It can be seen that the two nanofibrous components were integrated together, where the PVA nanofibrous component was cross-linked by glutaraldehyde (GA) working as a mechanical support of the membrane, and the PAN nanofibrous component could be further functionalized independently. The PAN component was further modified by surface grafting or hydrolysis to fabricate composite microfiltration membranes which exhibited high separation efficiency and selectivity for particular sized-microspheres, while positively charged or negatively charged nature enabled impressive adsorption capability, as demonstrated by the removal of chromium (VI) and cadmium (II) ions from contaminated water, respectively.
研究领域:
环境科学
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材料科学
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水处理
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产品关联
DOI
高影响因子
Journal of Materials Chemistry A
·
2014
·Vol. 2
·期 43
·18304-18312
·
IF 0
Yan Li,Lihuan Wang,Xia Yin,Bin Ding,Gang Sun,Tao Ke,Jingyuan Chen,Jianyong Yu
Given the dire consequences of accidental lead ion (Pb2+) exposure, a portable, sensitive and robust analytical approach capable of colorimetric visualization is highly desirable. In this study, we demonstrate a colorimetric strip that relies on a novel polydiacetylene (PDA) embedded polyacrylonitrile nanofibrous membrane (PAN NFM). The Pb2+-chromic PDA is prepared from controlled mixtures of 10,12-pentacosadiynoic acid (PCDA) and PCDA-5EG, a PCDA derivative with a pentaethylene glycol headgroup. Moreover, the Pb2+ complexation ability is manipulated by controlling the molar ratio of PCDA to PCDA-5EG. The PAN NFM acting as a three dimensional matrix is designed for PDA immobilization, thereby improving the stability, portability and sensitivity. Upon exposure to a series of metal ions, only Pb2+ could induce a color change, which clearly showed that our strip could act as a highly selective probe to detect Pb2+. Ultimately, the strip with a naked eye detection limit of 0.48 μM undergoes a brilliant color transition, from blue to red, in a concentration-dependent manner and all the color transitions of strips are quantitatively visualized by employing a chromatic framework. The findings indicate that the strip is particularly promising for visual Pb2+ recognition due to its facile functionalization, simple construction, and versatility to empower colorimetric signaling.
研究领域:
分析化学
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材料科学
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环境科学
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产品关联
DOI
JOURNAL OF ENVIRONMENTAL MANAGEMENT
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2025
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IF 8.4
Qixun Nian,Huayin Zhang,Kai Wang,Chunmin Wang,Qiuping Zhang,Qian Xu
The extensive use of antibiotics has led to the co-occurrence of multiple antibiotic classes in environmental water, necessitating efficient removal strategies. In this study, MOF-801@polydopamine@polyacrylonitrile nanofiber membranes (MOF-801@PDA@PAN NFMs) were synthesized via thermally initiated polymerization and layer-by-layer self-assembly for the simultaneous adsorption of 32 antibiotics from six major categories. Theoretical and experimental analyses confirmed rapid adsorption (within 10 min) through electrostatic attraction, hydrogen bonding, π-π interactions, and metal complexation. The membranes achieved removal efficiencies ranging from 39.22% to 98.83% and followed pseudo-second-order kinetics. Regeneration tests demonstrated stable performance over 15 reuse cycles. Compared to existing methods, these membranes offer broader-spectrum removal, higher efficiency, faster kinetics, and reduced adsorbent dosage. Additionally, they operate without pH or ionic strength adjustments and eliminate the need for post-treatment separation, highlighting their practical potential for environmental remediation. These findings offer a promising platform for scalable, cost-effective treatment of antibiotic-contaminated water.
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产品关联
DOI
高影响因子
Journal of Water Process Engineering
·
2025
·
IF 6.7
Abdul Qadir,Adeel Ahmed,Pervaiz Ahmad,Aisha H. Albalawi,Zahrah Alqahtani,Haia H. Aldosari,Raza Ullah,A. Timoumi,Awais Khalid
Metal–organic frameworks (MOFs) have currently attracted interest as effective self-sacrificial templates for the fabrication of hierarchical porous metal–nanoparticle materials. This study involved the synthesis of Cu-based MOF-loaded polyacrylonitrile (MOF/PAN) fibers using electrospinning, subsequently subjected to calcination in a nitrogen environment to yield Cu nanoparticle-loaded carbon nanorods (Cu@CNRs) as heterogeneous catalysts. The catalytic performance of prepared Cu@CNRs was investigated via hydrogen peroxide (H 2 O 2 ), peroxydisulfate (S 2 O 8 2− ), and peroxymonosulfate (HSO 5 − ) activated degradation of sulfamethoxazole (SMX). The activation performance of Cu@CNRs followed the sequence: HSO 5 − > S 2 O 8 2− > H 2 O 2 , indicating that HSO 5 − was the most effective oxidant under identical conditions. The Cu@CNR-I/HSO 5 − system demonstrated exceptional efficacy, attaining 99.99 % SMX removal in 30 min and a significant rate constant of 0.2312 min −1 . The improved activity is due to the hierarchical porous structure, elevated surface area, plentiful active sites, and robust Cu-N-C/HSO 5 − synergy. The carbonization created a polarization disparity in Cu N coordination, thereby promoting PMS activation by Cu(I/II) species. Radical quenching and EPR tests revealed that SO₄ •- and OH • radicals predominated the degradation route. The primary operating factors, such as catalyst and oxidant dose, solution pH, SMX concentration, coexisting anions, and humic acid, were carefully examined. The catalyst Cu@CNR-I exhibited remarkable catalytic stability and reusability over five cycles, indicating significant potential as a sustainable heterogeneous catalyst for wastewater treatment applications.
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产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 47
·41420-41427
·
IF 3.289
Guohui Li,Avinav G. Nandgaonkar,Keyu Lu,Wendy E. Krause,Lucian A. Lucia,Qufu Wei
The engineering of supports for enzyme immobilization while retaining competent functionality is nontrivial. We attempted to enhance the removal efficiency of organics by adopting a relatively novel approach involving a synergy from the adsorption capabilities of a support incorporated with organically modified montmorillonite (O-MMT) and catalytic properties of immobilized laccase. Electrospun polyacrylonitrile (PAN)/O-MMT membranes after alkaline hydrolysis and carboxyl activation were chosen as the support system for laccase immobilization. A confocal laser scanning microscope confirmed a uniform enzyme distribution along with the fibers' longitudinal surface. After enzyme immobilization, the optimum pH shifted from 3 to 3.5, while the optimum temperature remain unchanged at 50 °C. Its stability was preserved despite a large fluctuation in pH (50% of its initial activity retained over the pH range 2–6) and temperature (more than 80% of its initial activity retained over 30–70 °C). Compared to free laccase, the thermal stability of the immobilized laccase was improved after being under 30 °C and 50 °C for 8 h. The operational stability was 68% of the initial one after 10 times repeated usage, while also demonstrating 80% storage stability of the initial activity even after two months. The immobilized laccase showed a high removal efficiency of crystal violet at an optimum pH of 5 and temperature ∼40 °C as well as an initial substrate concentration of 100 mg L−1. Compared with that of the individual support and the free laccase, the removal efficiency by an immobilized enzyme is far higher to confirm a synergy in the immobilized enzyme and support system.
研究领域:
生物技术
·
环境科学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry A
·
2026
·
IF 9.2
Zhao Meng,Haibo Yang,Yongzhen Ma,Yan Cheng,Yanlong Ma,Binglong Zheng,Hongwei Zhou,Ying Lin
In increasingly complex electromagnetic environments, developing high-performance and dynamically tunable electromagnetic wave (EMW) absorption materials is essential. This study designed a pressure-responsive TiO2/CNFs@Co/C elastic aerogel for efficient EMW absorption. A 3D interpenetrating structure consisting of Ti3C2Tx MXene-derived TiO2 nanosheets, magnetic Co/C frameworks, and carbon nanofibers was constructed via electrospinning combined with in situ synthesis. This 3D interpenetrating structure constructs abundant heterogeneous interfaces, thereby enhancing interfacial polarization. The results demonstrate that the composite achieves an exceptionally broad effective absorption bandwidth (EAB) of 8.17 GHz at a thickness of 2.7 mm, with only 10 wt% filler loading. Additionally, the composite exhibits strong environmental tolerance, including hydrophobicity, stretchability, and thermal insulation. Notably, the alginate-induced elastic aerogels enable dynamic tuning from 6.4 to 18 GHz under compressive strains of 0% to 66%. This work designs dynamically tunable, high-performance EMW absorbers through component optimization and interface engineering, providing a promising strategy for the preparation of next-generation multifunctional intelligent EMW absorbers.
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产品关联
DOI
高影响因子
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