DALTON TRANSACTIONS
·
2023
·Vol. 52
·期 46
·17148-17162
·
IF 4
Yunqi Xu,Kang Wang,Yi Zhu,Jing Wang,Dazheng Ci,Min Sang,Qunling Fang,Huaxia Deng,Xinglong Gong,Ken Cham-Fai Leung,Shouhu Xuan
The global health crisis of bacterial resistance to antibiotics requires innovative antibacterial strategies. One promising solution is the exploitation of multifunctional nanoplatforms based on non-resistant antibacterial mechanisms. This work reports a novel Fe3O4@Au/polydopamine (PDA) nanodurian with excellent photothermal-magnetomechanic synergistic antibacterial effects. The one-step formed Au/PDA hybrid shell provides good photothermal properties and spiky surfaces for enhanced magnetomechanic effects. Upon near-infrared (NIR) irradiation, the Fe3O4@Au/PDA nanodurian (200 μg mL−1) achieved nearly 100% antibacterial effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The efficiency of photothermal antimicrobial activity was further enhanced by the application of a rotating magnetic field (RMF), with the sterilization efficiency being increased by up to more than a half compared to the action alone. Interestingly, the size of the nanodurian has a significant impact on the synergistic sterilization effect, with larger particles showing a superior performance due to stronger chain-like structures in the magnetic field. Finally, the Fe3O4@Au/PDA nanodurian also demonstrates effective biofilm removal, with larger particles exhibiting the best eradication effect under the photothermal-magnetomechanic treatment. Overall, this magnetic field enhanced photothermal antibacterial strategy provides a promising broad-spectrum antimicrobial solution to combat bacterial infections. Thus, it possesses great potential in future nanomedicine and pollution treatment.
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高影响因子
EUROPEAN POLYMER JOURNAL
·
2024
·
IF 5.8
Fan Zhang,Meng-hang Gao,Chao-qun Wu,Jing-hui Yang,Nan Zhang,Yong Wang
In today’s electric power systems, biodegradable and environmentally benign dielectric materials with outstanding dielectric capabilities are essential. Here, a hybrid filler MXene@PDA (M@P) was acquired by coating MXene with polydopamine (PDA), and then it was added into cellulose matrix to manufacture regenerated cellulose/M@P (RC/M@P) composite films. Finally, a crosslinking strategy with glutaraldehyde (GA) assistance was developed to further modify the RC/M@P composite films. The crosslinked composite films (CRC/M@P) had a denser structure with fewer defects, considerably decreased dielectric loss, and significantly strengthened breakdown strength. The highest energy storage density of 3.37 J/cm 3 was obtained for CRC/M@P-1 composite film with only 1 wt% M@P at 361.07 MV/m, achieving significant enhancement compared with the original CRC film. Moreover, crosslinking also contributed to the CRC/M@P for achieving better mechanical properties. The excellent comprehensive performances endow CRC/M@P composite films with promising application for the next-generation dielectric capacitors.
研究领域:
材料科学
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环境科学
·
能源工程
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NANOTECHNOLOGY
·
2020
·Vol. 31
·期 21
·215606
·
IF 3.551
Haifeng Niu,Jianbo Li,Xuefang Wang,Zhe Qiang,Jie Ren
We demonstrated a simple approach for fabricating Au–Fe3O4/PDA hollow nanoparticles as high-performance catalysts for water purification. The polydopamine (PDA) shell was in situ formed on the silica surface from self-polymerization, which acts as a medium support for coupling with metal ions (for Fe3O4 nanoparticle deposition) as well as a reducing agent and stabilizer for Au nanoparticle reduction and deposition. A step of simultaneous Fe3O4 nanoparticle deposition and silica core removal under alkaline conditions is first introduced in this study. This process significantly simplifies previous strategies which typically require the use of poisonous agents such as hydrogen fluoride or additional complicated post-treatment steps. Under optimized conditions, the Au–Fe3O4/PDA hollow nanoparticles show a high saturation magnetization of 18.8 emu g−1 and an excellent catalytic performance for the rapid reduction of p-nitrophenol with the reaction kinetic constant of 0.34 min−1. This catalyst can be easily recovered using a permanent magnet and recycled eight times with a high catalytic cycle stability. The strategy presented in this work provides a facile and versatile approach towards designing complicated Au–Fe3O4/PDA hollow nanostructures, which might have great potential for many applications within biological, energy, and environmental technologies.
研究领域:
材料科学
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环境科学
·
纳米技术
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RSC Advances
·
2017
·Vol. 7
·期 75
·47715-47725
·
IF 3.108
Le Shang,Qiu-yue Wang,Kang-long Chen,Jing Qu,Qing-han Zhou,Jian-bin Luo,Juan Lin
In this research, reducible polydopamine coated magnetic nanoparticles (SPIONs@PDA) were prepared and doxorubicin (DOX) was encapsulated for both magnetic resonance imaging (MRI) detection and cell targeting drug delivery. The SPIONs@PDA exhibited excellent water-solubility and colloidal stability, because the coating of the magnetic nanoparticle was a crosslinked reducible polydopamine synthesized with N,N-bis(acrylate) cystamine (BACy) as a crosslinker, dopamine methacrylamide (DMA) as an anchor to immobilize SPIONs, and polyethylene glycol (PEG) to provide colloidal stability. The SPIONs@PDA showed reduction-sensitivity due to the reducible disulfide bond in the polymer network. Subsequently, a sustained and high cumulative drug release in glutathione (GSH) was observed, rather than the low drug release in PBS (pH 7.4). Fluorescent imaging studies by confocal laser scanning microscopy indicated that the prepared SPIONs@PDA could specifically target tumor cells. The results of the cytotoxicity assays further demonstrated that the DOX-loaded SPIONs@PDA presented efficient antitumor activity to HeLa cells. These favorable properties suggested SPIONs@PDA as promising targeted magnetic nanoparticles for MRI detection and stimuli-triggered drug delivery in cancer theranostics.
研究领域:
生物材料学
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医学影像学
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肿瘤学
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APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Libo Sun,Qingtai Xie,Heshun Jing,Xueqing Liu,Lijun Zhao,Xun Sun,Baorong Duan,Caixia Qi,Huijuan Su
Here, Au/polydopamine (Au/PDA) catalysts were prepared by gold sol adsorption (Au/PDA(Sol)), PDA in situ reduction (Au/PDA(PDA reduction)) and DA in situ reduction (Au/PDA(DA reduction)). The factors that influence the performance of Au-PDA on the reduction of 4-nitrophenol (4-NP), were systematically studied for the first time. The catalytic performance of Au/PDA(Sol) is the best because of the uniform and small size of Au nanoparticles (NPs) (3.2 ± 0.7 nm), with a turn over frequency (TOF) of 10125 h −1 , a mass-normalized rate constant ( k’ ) of 33360 min -1 g Au -1 and an apparent activation energy (Ea) of 11.39 KJ/mol. It is confirmed that there are electronic interactions between Au and the catechol hydroxyl groups and imino groups of PDA. Some unreduced Au 3+ ions can be reduced in situ by NaBH 4 during the catalytic reaction, forming ultra small Au NPs and leading to a good initial catalytic activity, especially for Au/PDA(DA reduction). This work systematically studied the influencing factors in catalysis for Au/PDA, providing guidance for the preparation and industrial application of PDA supported noble metal catalysts.
研究领域:
化学
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材料科学
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催化反应
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CRYSTENGCOMM
·
2021
·Vol. 23
·期 37
·6610-6619
·
IF 3.545
Qunling Fang,Kezhu Xu,Qingshan Xiong,Yunqi Xu,Ailing Hui,Shouhu Xuan
Infectious diseases associated with drug-resistant bacteria increasingly threaten public health. Effective antibacterial nanoplatforms are of special importance for treating bacterial infections. In this work, a novel magnetic Fe3O4–Au–PDA hybrid microcapsule with both photothermal (PTT) and photodynamic (PDT) anti-bacterial functions was developed. First, the Fe3O4@Au/PDA core/shell microspheres with hollow nature were obtained by a simple in situ redox–oxidize polymerization method. Then, they were etched in acid to improve the hollow interior and porous shell. Finally, the tetracarboxyzinc phthalocyanine (ZnPc) was used as the photosensitizer to be loaded into the above Fe3O4–Au–PDA hybrid microcapsule. Owing to the dual-mode photothermal Au–PDA hybrid shell and the ZnPc photosensitizer, the final Fe3O4–Au–PDA/ZnPc hybrid microcapsule serves as a wonderful photothermal/photodynamic (PTT/PDT) synergistic therapy agent. The experimental results show that the Fe3O4–Au–PDA/ZnPc microcapsule possesses excellent photothermal sterilization effect (808 nm laser irradiation) against Escherichia coli, and the experimental results further demonstrate good photodynamic behavior under Xenon lamp irradiation. The product exhibits much higher antibacterial performance by combining the PTT/PDT treatment, which demonstrates that this work provides a novel dual-mode phototheranostic nano-agent for an effective treatment of bacterial infections.
研究领域:
纳米医学
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材料科学
·
微生物学
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LANGMUIR
·
2022
·
IF 4.331
Qing Sun,Bin Xiang,Peng Mu,Jian Li
Developing high-performance membranes is an extremely significant strategy to combat increasing severe oil pollution. However, most of the previously reported superwettable membranes have been inevitably involved with the use of toxic solvents and complicated preparation processes. In addition, most of them lacked the capacity of separating crude oil-in-water emulsions. Herein, a facile and green strategy is employed to fabricate a polytetrafluoroethylene (PTFE) membrane with a mixed suspension of PDA@ZIF-8 and carboxymethyl cellulose (CMC) using water as a solvent via the vacuum filtration method. Combining hydrophilic property with micro–nano-roughness, the CMC-PDA@ZIF-8-coated PTFE membrane (CPZP membrane) exhibits excellent underwater superoleophobicity. More importantly, the separation efficiency of various surfactant-stabilized oil-in-water emulsions including crude oil/water emulsion is higher than 99.2% with a flux up to 1306.5 L m–2 h–1, and the separation performance remains nearly the same after 10 cycles. Moreover, outstanding underwater superoleophobic and self-cleaning properties are maintained after long-distance sandpaper abrasion and multiple bending tests. Meanwhile, its exceptional separation performance is still maintained in harsh environments (3.5 wt % NaCl, 1 M HCl, 60 °C hot water) even after immersing it for 24 h. Therefore, this green-prepared and high-performance membrane has tremendous application prospects in treating oily wastewater.
研究领域:
环境科学
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材料科学
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Biotechnology Journal
·
2025
·Vol. 20
·期 12
·e70169
·
IF 3.1
Yiran Tang,Jie Xu,Wang Liu,Jingjing Zhu,Huan Fang,Langyu He,Hongxi Liu,Yuen Yee Cheng,Xiangqin Li,Huanwei Sun,Wei Zhang,Kedong Song
Cardiovascular diseases are a leading global cause of mortality, with cardiac patches (CPs) emerging as a novel surgical treatment. This study used a combined decellularization method with sodium dodecyl sulfate (SDS), Triton X-100, and DNase to process porcine myocardial tissue (PMT), yielding decellularized extracellular matrix (dECM). Quantitative analysis revealed that the dECM contained collagen, DNA, and glycosaminoglycans (GAGs) at concentrations of 2.63 ± 0.37 µg/mg, 4.27 ± 0.79 ng/mg, and 15.94 ± 0.60 µg/mg. Additionally, a conductive hydrogel patch (PDA/CSCA/PAM) with a uniform porous structure and excellent mechanical properties was developed. Its adhesive strengths on glass, stainless steel, and PMT were 50.71 ± 2.88 kPa, 34.19 ± 3.63 kPa, and 54.71 ± 3.24 kPa, respectively. Bacterial inhibition rates reached 103.26 ± 3.52% (Day 1) and 99.26 ± 5.35% (Day 3), indicating significant antimicrobial efficacy. The patch met myocardial tissue engineering standards for swelling ratio, hydrophilicity (contact angle <90°), hemolysis rate (<5%), and conductivity (10 −4 S cm −1) , with biosafety certified by ISO 10993-5. These results highlight its mechanical compatibility, antimicrobial activity, and biocompatibility, offering a multifunctional solution for myocardial infarction repair with high clinical translation potential.
研究领域:
心血管工程
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生物医学材料
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组织工程
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再生医学
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生物材料科学
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Soft Matter
·
2019
·Vol. 16
·期 1
·132-141
·
IF 3.399
Yangjie Xu,Jiulong Zhao,Zhilun Zhang,Jing Zhang,Mingxian Huang,Shige Wang,Pei Xie
In this study, sodium alginate (ALG)/poly dopamine (PDA)–polyvinylpyrrolidone (PVP) nanocomposites was synthesized via a one-step electrostatic spraying method. The spinning solution of ALG and dopamine was electrostatically sprayed into an alkaline solution of PVP, calcium chloride and tris buffer (pH = 8.5), in which the gelation of ALG and the polymerization of dopamine could be simultaneously triggered. PDA hence produced possesses a high photothermal conversion efficiency, while the PVP that was facilely conjugated onto the surface of nanocomposites improves the colloidal stability and compatibility of the material. Moreover, the ALG renders the nanocomposite excellent drug (doxorubicine, DOX) loading capacity. Promisingly, the temperature increment during the PTT process could promote the DOX release, thus enhancing its therapeutic effect. The in vitro/in vivo biosafety and tumor treatment experiments further corroborate that the ALG/PDA–PVP nanocomposites have remarkable biocompatibility and synergism for tumor hyperthermia and chemotherapy. Consequently, such a one-step electrospray strategy provides a new way for designing nanomaterials and is expected to significantly promote the development of organic photothermal therapeutic agents with excellent bio-compatibility.
研究领域:
生物医学工程
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纳米医学
·
癌症治疗
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高影响因子
ACS Applied Materials & Interfaces
·
2026
·
IF 8.2
Qixu Yu,Yujun Wei,Jing Zhang,Shumeng Wu,Sihui Chen,Zhijian Huang,Lelun Jiang,Junyang Tao,Guanwei Liang,Shudong Yu
Freshwater scarcity has become a critical global issue, highlighting the urgent need for low-cost and efficient technologies for seawater desalination and wastewater purification. Inspired by the hopper-shaped corolla of the Morning Glory, which efficiently concentrates sunlight and directs water along its conical surface, we developed a paper-based solar evaporator constructed from cellulose paper via laser-induced graphene (LIG) and further modified with polydopamine (PDA) to enhance hydrophilicity. The paper substrate was folded into a three-dimensional (3D) conical structure, which enlarged the evaporation area, improved light absorption, and optimized thermal management. Under 1 sun irradiation, the optimized 3D device achieved an evaporation rate of 2.02 kg m–2 h–1 with an efficiency of 125.1%, outperforming its two-dimensional counterpart. The conical geometry also facilitated edge crystallization of salts, ensuring long-term operational stability. Outdoor tests further verified its capability for freshwater production, demonstrating the potential of this bioinspired, low-cost, and scalable paper-based evaporator for sustainable desalination and clean water generation.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2022
·Vol. 33
·期 9
·6563-6575
·
IF 2.779
Li Jie,Xu Sai,Yu Yang,Liu Kaiying,Gao Yuefeng,Chen Baojiu
Multifunctional nanoparticles with marvelous temperature sensing and photothermal conversion are preferable in photothermal therapeutic applications. Herein, nanocomposites of NaYF 4 :Er 3+ /Yb 3+ @NaYF 4 :Nd 3+ /Yb 3+ core–shell upconversion nanoparticles (UCNPs) modified by polydopamine (PDA) were designed to achieve temperature sensing and efficiency of photothermal conversion. It has been found that under the irradiation of 808 nm laser, temperature sensing can be realized on the basis of the fluorescence intensity ratio of Er 3+ green light emission. In addition, the photothermal conversion ability of the UCNPs modified by PDA is greatly improved. Moreover, Nd 3+ as activator endows UNCPs excited by 808 nm, which can avoid overheating due to the absorption of the excitation band (980 nm) in water. Therefore, the multifunctional nanoparticles are expected to become an effective drug for cancer therapy in the future and this research will stimulate interest in designing multifunctional nanoparticles that are biocompatible, especially for in vivo tumor diagnosis.
研究领域:
生物医学工程
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材料科学
·
纳米医学
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高影响因子
FIBERS AND POLYMERS
·
2023
·Vol. 25
·期 2
·437-445
·
IF 2.5
Huang Peijun,Liu Yan,Chen Zhuoming,Zheng Yuansheng,Vasilovna Khammatova Venera,Faritovich Gainutdinov Ruslan,Xin Binjie
Polypyrrole (PPy) is one of the most widely researched conductive polymers due to its high electrical conductivity, good thermal and environmental stability, oxygen resistance, heterocyclic structure, non-toxicity, and simple synthesis method, and is an excellent candidate for electric heating materials. For better application in textile heating, a polyurethane (PU) film is used as a substrate and dopamine (PDA) is used as a multifunctional platform for the secondary reaction on the film to immobilize the polypyrrole on the surface of the film, making it a smart wearable element. By varying the amount of PPy to control its direct oxidative polymerization reaction, materials with good electrical conductivity and flexibility were obtained. It has a fast electrothermal response at low operating voltages (up to 118 °C after 20 s at 5 V), good flexibility, light weight and uniform heat distribution. It has significant advantages compared to other electrical heating materials.
研究领域:
材料科学
·
高分子科学
·
电气工程
·
纳米技术
·
化学合成
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高影响因子
危险品化学品经营许可证（带存储）