MATERIALS CHEMISTRY AND PHYSICS
·
2025
·
IF 4.7
Junqin Mao,Yutong Zhang,Tao Shen,Qiuyu Zeng,Wanli Zhang,Xinyu Zhang,Qiang Liu,Heng Zheng,Guoyu Lv
As gastric ulcers remain a significant clinical challenge, this study presents the development of a flexible microneedle system based on cerium/zinc-doped bioactive glass (CeZnBG) and a PCL/PLA matrix for targeted ulcer therapy. The design leverages the synergistic antioxidant and antibacterial properties of CeZnBG, combined with the localized drug delivery capability of microneedles, to enhance ulcer healing. CeZnBG was synthesized via high-temperature sintering at various temperatures (950 °C, 1050 °C, 1150 °C, and 1250 °C), and subsequently incorporated into PCL/PLA microneedles (PCMN) at doping concentrations of 0.5 %, 1.5 %, and 2.5 % to form composite materials. The structural and physicochemical characteristics of the CeZnBG-PCMN, were investigated using X-ray diffraction (XRD), scanning electron microscopy (SEM), Energy Dispersive X-ray Spectroscopy (EDS), mechanical properties, differential scanning calorimetry (DSC), and X-ray photoelectron spectroscopy (XPS). In vitro assays, including ROS scavenging and cytocompatibility, were used to assess the bioactivity of the composites. The results demonstrated that PCMN containing 1.5 % CeZnBG maintained excellent cytocompatibility (with relative cell viability exceeding 80 %) while exhibiting notable antibacterial performance, indicating promising potential for targeted gastric ulcer repair.
研究领域:
生物医学工程
·
药剂学
·
组织工程
·
纳米医学
·
消化病学
·
材料科学
·
转化医学
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2013
·
IF 3.479
Zhu Xiong,Lisheng Zhang,Songqi Ma,Yong Yang,Chuanzhi Zhang,Zhaobin Tang,Jin Zhu
Blends of entirely bio-sourced polymers, namely polylactide (PLA) and starch, have been melt-compounded by lab-scale co-extruder with castor oil (CO) as a plasticizer. The enrichment of castor oil on starch had great effect on the properties of the blends. If the castor oil was mainly dispersed in PLA matrix, the properties of the blends were poor, but when the hexamethylenediisocyanate (HDI) was grafted on starch granules the ready reactions between the hydroxyl on CO and the isocyante on the HDI-grafted starch (HGSTs) brought CO molecules enriched on starch particles. DSC analysis shows that the CO layer on starch has a positive effect on the crystallization of PLA in the ternary blend. The accumulation of CO on starch greatly improves the toughness and impact strength of PLA/starch blends. The grafting content of HDI on the starch granules primarily determined the compatibility and properties of the resulted blends.
研究领域:
材料科学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Rui Luan,Ziyao Zhao,Yuan Yuan,Chunxia Wang,Mei-Xian Li,Yu Ren
This study aimed to enhance the antibacterial and biocompatible properties of PLA nonwoven materials by plasma-assisted surface decoration with selenium nanoparticles. PLA nonwoven materials were pretreated by plasma surface modification technology for varying durations. Subsequently, Se nanoparticles obtained from the redox reaction of sodium selenite were loaded onto the PLA surfaces through impregnation. SEM images demonstrated that plasma pretreatment enhances the uniformity of Se nanoparticles as well as the contents loaded onto the PLA nonwoven materials. Based on EDS analysis, the relative concentration of Se elements increased with longer plasma pretreatment durations, reaching 6.38% after 6 min of treatment. XPS analysis confirmed the presence of elemental selenium nanoparticles. Furthermore, the results of surface wettability showed that the surface of Se/PLA composites changed from hydrophobic to super hydrophilic after the plasma and Se combined treatment. Moreover, bacterial inhibition of the Se/PLA composites substantially improved with increasing plasma pretreatment time. The Se/PLA composites with 6 min of plasma pretreatment showed the best antibacterial performance and biocompatibility, with inhibition rates against Staphylococcus aureus and Escherichia coli reaching 95.75% and 75.54%, respectively, and cell viability was over 99% for L929 cells. These functionalized Se/PLA composites exhibit tremendous potential for applications in novel antibacterial materials.
研究领域:
材料科学
·
生物学
·
医学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2025
·
IF 11.3
Haicheng Huang,Chaopei Chen,Somia Yassin Hussain Abdalkarim,Yuheng Liu,Kaiwei Chen,Sherif Mehanny,Hou-Yong Yu
Polylactic acid (PLA) is widely used in crop protection but faces challenges such as low toughness and unpredictable degradation rates. This study addresses these limitations by developing a green and durable mulch film incorporating citric acid-modified cellulose nanocrystals (CA-CNC) as an interfacial compatibilizer in PLA. Adding CA-CNC enhances the orientation of PLA molecular chains, thereby improving tensile ductility. Specifically, incorporating 5 % CA-CNC significantly increased tensile strength by 28.2 %, while toughness surged by 190.1 %. Mulch films were subjected to indoor UV light and outdoor degradation in soil and cultivation environments (using soybean as a case study) to explore degradation mechanisms. Notably, the mulch film with 5 % CA-CNC completely fragmented after 140 days of soil degradation, representing a higher degradation rate of 31.9 %. Meanwhile, the degradation rates observed after 90 days of outdoor cultivation environment degradation (9.8 %) and 30 days of indoor UV degradation (2.8 %) exhibit distinctions compared to outdoor soil degradation. Further analyses of changes in the physicochemical properties of mulch film confirmed the degradation mechanisms. This study provides valuable insights for estimating short-term indoor and long-term outdoor degradation of mulch films, underlining their significance in sustainable agricultural practices.
研究领域:
材料科学
·
农业科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2024
·
IF 7.1
Wenlong Pang,Bin Li,Yufeng Wu,Yu Zhang,Jun Yang,Zhongxun Tian,Shaonan Tian,Jianjun Li
Biodegradable plastics such as polylactic acid (PLA) have been extensively applied in numerous fields. Although PLA is degradable in natural environments, its decomposition postdisposal leads to resource wastage. Herein, we first employ enzymatic hydrolysis to degrade PLA. Subsequently, PtPb alloy nanoparticles are synthesized in a single step via a wet chemical method, catalyzing the reformation of the PLA enzymatic hydrolysis products into higher-value chemicals (pyruvic acid). Under conditions of an oxygen flow rate of 60 mL/min, a reaction temperature of 90 °C, and a reaction duration of 60 min, the conversion rate of lactic acid catalytic oxidative dehydrogenation to pyruvic acid reaches an impressive 96.86%, with a selectivity of 95.69%. Moreover, this catalyst exhibits satisfactory stability. Experimental and density functional theory (DFT) calculations are combined to ascertain the active state changes of PtPb and the reaction pathways for the catalytic oxidative dehydrogenation of lactic acid to pyruvic acid, as well as the free energy changes of different catalysts in this transformation. In this work, we employ a simple synthetic strategy to specifically investigate the impact of PtPb alloy nanoparticles under various conditions on the catalytic oxidative dehydrogenation of lactic acid to pyruvic acid, offering a new research avenue for the waste treatment and resource utilization of biodegradable plastics in the future.
研究领域:
材料科学
·
环境科学
·
催化化学
✓ 已验证
产品关联
DOI
高影响因子
LANGMUIR
·
2011
·
IF 4.269
Bin Xu,Hongjing Dou,Ke Tao,Kang Sun,Jing Ding,Weibin Shi,Xiasheng Guo,Jiyu Li,Dong Zhang,Kun Sun
A new method for the fabrication of Fe3O4 nanoparticles enveloped by polymeric nanocapsules is proposed. This method is characterized by combining a double emulsification with the interfacial coprecipitation of iron salts to form Fe3O4/polymer composite nanocapsules in a single step. To demonstrate the viability of this approach, methoxy poly(ethylene glycol)-poly(lactide) (MePLEG) was chosen as the shell material for Fe3O4/MePLEG nanocapsules. In addition to the versatility offered for fabricating nanocapsules with different shell materials, the method was found to be convenient for adjusting the magnetite content of the nanocapsules from 0 to 43%. In addition to their confirmed T2-weighted magnetic resonance imaging (MRI) enhancement, the resultant composite nanocapsules display much more obvious acoustic responses than MePLEG nanocapsules in an acoustic investigation. Furthermore, the low toxicity of these composite nanocapsules, as confirmed by our study, combined with their magnetic and acoustic properties ensure that these composite nanocapsules have great potential in acting as ultrasonic/MRI dual contrast agents.
研究领域:
材料科学
·
医学影像学
·
纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2026
·
IF 6.4
Pengjie Zhang,Houyong Yu,Yunfei Shen,Jiayuan Shen,Xuefei Chen
Mechanical shearing-mediated acid hydrolysis with only 1.55% HCl achieved a 96.65% MCC yield. • The resulting MCC exhibited high crystallinity, good thermal stability, and uniform particle size. • As a reinforcing agent, MCC improved PLA crystallization, mechanical properties, water vapor barrier and food preservation. • Life cycle assessment confirmed lower environmental impacts of the proposed MCC process than commercial MCC production. Conventional microcrystalline cellulose (MCC) production generally relies on high-concentration acid hydrolysis, leading to low yield (<90%), substantial energy consumption and environmental pollution. Herein, this study presents a sustainable and efficient strategy for preparing MCC via ultra-low hydrochloric acid (HCl) hydrolysis mediated by mechanical shearing force to overcome these bottlenecks. This optimized process achieved an exceptional yield of 96.65% at an extremely low HCl concentration of merely 1.55% at 90 °C for 95 min, far below the acid dosages employed in current methods. The improved hydrolysis efficiency stemmed from the mechanical shearing force, which effectively disrupted the intermolecular hydrogen bonds of cellulose, thereby loosening its structure and facilitating H⁺ penetration to promote glycosidic bond cleavage. The as-prepared MCC featured a uniform particle size (79.62 μm), high crystallinity (85.86%), excellent thermal stability (T max = 380.2 °C) and good dispersion stability, surpassing the overall performance of commercial MCC. As a reinforcing agent, MCC significantly improved the properties of polylactic acid (PLA) via hydrogen bonding and heterogeneous nucleation. Specifically, the PLA composite incorporated with 3 wt% MCC exhibited a 56.25% increase in tensile strength, a 24.92% improvement in elongation at break, a 40.11% enhancement in crystallinity, a 52.47% reduction in water vapor permeability (WVP), and a remarkable food preservation effect compared with neat PLA. Furthermore, life cycle assessment (LCA) indicated significantly lower environmental impacts of the ultra-low acid hydrolysis process relative to commercial MCC production. This work provides a sustainable and industrially viable route for MCC production, with broad application potential in food packaging, biomedical and composite materials.
✓ 已验证
产品关联
DOI
高影响因子
COMPOSITES SCIENCE AND TECHNOLOGY
·
2023
·
IF 9.1
Ling Yan,Somia Yassin Hussain Abdalkarim,Xuefei Chen,ZhiMing Chen,Weidong Lu,Jingli Zhu,Meijin Jin,Hou-Yong Yu
The demand for biopolymer-based green packaging has attracted growing attention because of its outstanding properties and consistency with clean environmental principle, unfortunately, its slow crystallization rate and narrow processing window are challenging. Inspired by combined functions in nanocellulose-based conductive hybrids, this work developed high-performance polylactic acid (PLA) composites using conductive cellulose nanofiber (CNFene). Interestingly, CNFene has multiple functions as highly graphitized carbon and abundant hydroxyl groups, delivering stimulating properties to PLA composites. As nucleating agents , 3 wt% CNFene has a carbon layer on the surface combined with a hydrogen bonding network synergistically enhancing the tensile and crystallization properties of PLA-C3, with a tensile strength of ∼ 53.7 MPa, crystallinity of ∼ 33.9 %, and 6.6 °C decrease in the cold crystallization temperature . Additionally, the compatibility between CNFene and PLA can form a multi-level “reinforcement” network structure, further improving thermal stability and barrier properties. The resultant PLA-C3 showed higher thermal decomposition onset temperature ( T 0 ), wider melt-processing window (197.6 °C) and extremely lower overall migration levels in ethanol (68.6 μg/kg) and isooctane (16.3 μg/kg), due to that improved interaction between CNFene and PLA positively affects crystallization ability and kinetic/mechanism of PLA to meet the requirements of industrial and green biopackaging applications.
✓ 已验证
产品关联
DOI
高影响因子
Coatings
·
2023
·Vol. 13
·期 10
·1686
·
IF 3.4
Hongyu Gong,Lin Li,Na Li,Lina Tian,Tao Zhang,Lexin Zhang,Tifeng Jiao
With the continuous application of antibacterial materials, various problems have emerged, such as expensive prices and the potential development of resistance. Cationic antibacterial agents, due to their high solubility, reactivity, and antibacterial properties, are considered as environmentally friendly and cost-effective antibacterial agents. In addition, the electrospinning technique is recognized as a versatile and high-efficiency method to produce nanofibers with multifunctional properties and adjustable structures. In this work, we prepared a series of nanofiber membranes by electrospinning technology using hexadecyl trimethyl ammonium Bromide (CTAB) and 5-Chloro-8-hydroxyquinoline (5-Cl8Q) as antibacterial agents and polylactic acid (PLA) as substrate. The antimicrobial performance of PLA/CTAB/5-Cl8Q was the highest among the prepared materials, which inhabitedS. aureusandE. coliup to 99.9% and 95.9%, respectively, and the antibacterial properties were stable. In general, PLA/CTAB/5-Cl8Q has great development potential, and it can be applied to real life as a cost-effective, biodegradable and highly antibacterial material.Keywords:electrospinning;composite nanofibers;cationic antibacterial agent;antibacterial
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Yijiao Xue,Tianchen Zhang,Linfeng Tian,Jiabing Feng,Fei Song,Zheng Pan,Meng Zhang,Yonghong Zhou,Pingan Song
To expand the practical application and realize sustainable development, it is urgent to develop advanced polylactide composites with fire retardancy and mechanically strong properties by utilizing bio-derived additives. Unfortunately, such desired performance portfolio is still unsatisfactory due to unclear mechanism and improper design strategy. In this paper, a novel bio-derived polyphosphonate containing Schiff base (PVP) was prepared by a two-step method of condensation and addition reactions. By incorporating only 0.5 wt% PVP, the LOI value of PLA is increased to 32.5 vol% as well as achieving a UL-94 V-0 rating. Such superior fire retardancy is ascribed to the physical barrier effect of char residue, which arising from the cyclization of Schiff base and catalytic carbonization of polyphosphonate. Due to the crosslinking reaction between PLA and PVP and nucleating effect of PVP in the PLA matrix, the mechanical strength of PLA is increased by 10.2% with addition of 1.0 wt% PVP. This study provides a feasible way for designing bio-derived fire retardants to simultaneously improving the fire retardancy and mechanical strength of PLA, thus is expected to expand the practical application of PLA materials.
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2019
·Vol. 43
·期 24
·9696-9705
·
IF 3.069
Yashi Chen,Qing Li,Xinhong Chen,Xi Xu
Although the construction process of dual functional materials for dye and oil/water separation has been developed rapidly, the postprocess of the used separation materials themselves is still a problem owing to their non-degradation in the natural environment. Herein, novel porous membranes (PLA–PEI) are successfully prepared based on the utilization of a dip-coating technique. The adsorption isotherms and kinetics present a good correlation with Langmuir isotherms and the pseudo-second-order model, respectively. The maximum adsorption capacity of PLA–PEI for methyl orange (MO) can reach 455.10 mg g−1, which is approximately 78 times as much as that of PLA (5.82 mg g−1). In addition, the separation efficiencies of three actual oils (methylbenzene, hexamethylene and soybean oil) are all higher than 99.7%. Moreover, the obtained membranes can realize high-efficiency and simultaneous removal of MO (removal efficiency > 99.8%) and oil droplets (oil rejection > 99.7%) from mixed wastewater under a permeate flux of up to 8285 L m−2 h−1 solely driven by gravity. These results suggest that PLA–PEI is a promising and competitive candidate for water purification.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 139
·期 28
·e52621
·
IF 3.057
Xiao-Qiong Cheng,Wei Liu,Chun Zhang,Xiao-Cheng Chen,Shu-Qian Duan,Hai Fu
In recent years, the problem of oily sewage has seriously affected the ecological environment and human health. Thus, we prepared a novel biodegradable poly (lactic acid) (PLA) membrane with antibacterial property and oil–water separation function via electrospinning method. First, the matter of silver ion glass microbeads (AgGB) loaded with layered double hydroxides (LDHs) and the LDH@AgGB modified with 3-triethoxysilyl-1-Propanamine (APTES) were synthesized. Then, the LDH@AgGB were blended with PLA to prepare PLA/LDH@AgGB composite. And the PLA nanofibrous membranes were electrospun. The results showed that APTES could significantly improve the dispersion and compatibility of LDH@AgGB in PLA matrix. The addition of A-LDH@AgGB could greatly improve the crystallinity, and control the porosity and pore-size of PLA membranes. The maximum water contact angle of the PLA membranes could reach to 109.31°, while the oil contact angle of the PLA membranes decreased to 0° resulting in a high oil absorption capacity, and fast oil absorption rate performance. Meanwhile, the PLA membrane had efficient antibacterial property against Escherichia coli . The reported novel LDH@AgGB and its PLA composite membrane provided a method for designing and preparing environmental-friendly, high-performance materials with both excellent antibacterial property and oil–water separation.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）