FUEL
·
2024
·
IF 6.7
Zunlong Hu,Peng Hu,Xiulin Wang,Tongtong Wu,Sida Ge,Haodong Xie,Baijun Liu,Shengli Chen,Zhijie Wu
The hydrocracking catalyst is characteristic of bifunctional catalyst mainly requiring metal–acid balance, which includes metal–acid ratio and metal–acid proximity. Here, we screened and clarified the optimal metal–acid balance on 1-methylnaphthalene (1-MN) hydrocracking by adjusting metal–acid ratio (n M /n A ) via physically mixing the γ-Al 2 O 3 supported NiW samples and Beta zeolite with different acidity (denoted as NiW/AB(x) and x presents the molar ratio of SiO 2 /Al 2 O 3 for Beta zeolite). NiW/AB(60) catalyst with a n M /n A of 0.40 showed the highest BTX selectivity (14.4 %) at a 1-MN conversion of 76.6 %, suggesting an optimal site balance between the metal sulfide site and medium-strong acid sites ( ca . 1:2.5). Also, four different metal–acid proximities with centimeter, millimeter, micrometer and nanoscale distances were compared. The nanoscale proximity enabled the highest BTX selectivity (19.6 %) as compared to the microscale (14.4 %), millimeter scale (12.4 %) and centimeter scale (7.1 %) catalysts, confirming that the selectivity of BTX benefited from the fast diffusion for transporting reaction intermediates between metal and acid sites. Thus, we realized a n M /n A of 0.40 and a nanoscale site proximity for improving the reactivity and selectivity of 1-MN hydrocracking. This work not only presents an elegant showcase of achieving the synergistic effects of bifunctional catalyst, but also provides a rational approach for enhancing the catalytic performance of hydrocracking and beyond.
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DOI
高影响因子
Journal of Energy Storage
·
2022
·
IF 8.907
Dengji Xu,Wanyu Shen,Shiqi Sun,Yanjun Chen,Zhumao Lu,Xiaokai Meng,Chao Wang,Li Guo,Changcheng Liu,Que Huang
The purpose of this study is to explore a new clean and environment protecting composite microcapsule material with 1-dodecanol (DD) as the core and modified methylated melamine-formaldehyde (MMF) as the shell, to meet the needs of low temperature heat or energy storage (0–40 °C). The microencapsulated phase change material (MPCM) base with a mass ratio of 14:3 was synthesized by in-situ emulsion polymerization , then two kinds of additives 10 wt% boron nitride (BN) and 5 wt% BN mixed with 5 wt% carbon nanotubes (CNTs) were applied to solve the defects of easy leakage and low thermal conductivity , while the samples were defined and shorted as BPCM and BCPCM, respectively. The experimental results showed that the prepared BCPCM presented good storage stability in the temperature range of 0–40 °C, which was due to its good thermal conductivity of 0.584 W/m·K, latent heat of 163.8 J/g, and strong supramolecular interaction between 1-DD and MMF. Through charging and discharging tests for batteries under low temperature, BCPCM indicated excellent thermal management performance, which proposed its application potential in the cryogenic storage environments and battery thermal management system (BTMS) field.
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高影响因子
IONICS
·
2021
·Vol. 27
·期 9
·3761-3768
·
IF 2.817
Li Wei,Ai Huiting,Liu Zheng,Wei Chuchu,Han Guo-Cheng,Zhan Ling
In order to improve the electrochemical properties of Na 2 MnPO 4 F (NMPF), low-cost biomass cane bagasse was used as a carbon source for coating, Na 3 V 2 (PO 4 ) 2 F 3 (NVPF) was used as a doped phase to prepare different ratios of xNa 3 V 2 (PO 4 ) 2 F 3 ·(1-x)Na 2 MnPO 4 F@C (NVPF/NMPF@C) composite materials via a sol–gel method. The results including analysis of XRD, SEM, EDS, and XPS methods showed that NVPF/NMPF@C (x = 0.2) composite material had good crystallinity, and NVPF can be uniformly doped in NMPF@C. The rate performance of NVPF/NMPF@C composite was tested at 0.1, 0.2, 0.5, 1, and 2 C. The first discharge specific capacity of NVPF/NMPF@C composite electrode material reached 193 mAh/g and increased by approximately 20 times when compared to only 9 mAh/g of NMPF@C. The coulombic efficiency of NVPF/NMPF@C material remained 95% after 35 cycles at 0.1 C. The introduction of NVPF can improve charge transfer and Li + diffusion, and enhance the electrochemical behavior of the lithium-ion battery cathodes.
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高影响因子
ACS Sustainable Chemistry & Engineering
·
2017
·
IF 5.951
Xinzhi Ma,Jing Wen,Shen Zhang,Haoran Yuan,Kaiyue Li,Feng Yan,Xitian Zhang,Yujin Chen
Development of noble-metal-free and active electrocatalysts is crucial for the oxygen evolution reaction (OER) in the water-splitting process. Herein, crystal CoxB catalysts (x = 1–3) of the OER are fabricated by a ball-milling method. Among these CoxB catalysts, Co2B exhibits the best OER activity, with a current density of 10 mA cm–2 at an overpotential of 287 mV in 1 M KOH solution. Such OER activity of Co2B is favorably comparable to that of the commercial IrO2 and most recently reported OER catalysts. Furthermore, the Co2B catalyst exhibits excellent stability with a stable current density of 50 mA cm–2 over 12 h of continuous electrolysis operation. X-ray photoelectron spectroscopy and cyclic voltammetry demonstrate that the B in CoxB makes oxidation easier, leading to their enhanced OER activities in comparison to metal Co. In addition, the Co2B electrocatalyst also exhibits high activity in the hydrogen evolution reaction; thus, the catalyst can be used as a bifunctional catalyst for full water splitting.
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高影响因子
Current Drug Delivery
·
2015
·Vol. 12
·期 6
·726-735
·
IF 1.478
Chenhui Wang,Changhui Yu,Kongtong Yu,Lesheng Teng,Jiaxin Liu,Xuesong Wang,Fengying Sun,Youxin Li
The use of biodegradable polymers such as PLGA to encapsulate therapeutic proteins for their controlled release has received tremendous interest. However, an acidic environment caused by PLGA degradation productions leads to protein incomplete release and chemical degradation. The aim of this study was to develop novel PCADK/PLGA microspheres to improve protein stability and release behavior. Bovine serum albumin (BSA) incubated in PCADK and PLGA degradation products was investigated using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), size exclusion chromatography (SEC-HPLC), circular dichroism (CD) and fluorescence spectroscopy. Blended microspheres of PCADK/PLGA were prepared in different ratios and the release behaviors of the microspheres and the protein stability were then measured. The degradation properties of the microspheres and the pH inside the microspheres were systematically investigated by scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM) to examine the mechanism of autocatalytic degradation and protein stability. BSA was more stable in the presence of PCADK monomers than it was in the presence of PLGA monomers, revealing that PCADK is highly compatible with this protein. PCADK/PLGA microspheres were successfully prepared, and 2/8 was determined to be the optimal ratio. Further, 43% of the BSA formed water-insoluble aggregates in the presence of PCADK/PLGA microspheres, compared with 57% for the PLGA microspheres, demonstrating that the BSA encapsulated in PCADK/PLGA blended microspheres was more stable than in PLGA microspheres. The PCADK/PLGA blended microspheres improved protein stability and release behavior, providing a promising protein drug delivery system.
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DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2018
·Vol. 43
·期 16
·7973-7981
·
IF 4.229
Shaowei Yang,Hui Xie,Hongwei Zhu,Lijuan Zhang,Yunshan Zhou,Huixian Zhang,Zipeng Zhao
In this work, metal-organic framework compound CPL-1 of a formula {[Cu 2 (pzdc) 2 (pyz)]⋅2H 2 O} n (pzdc = pyrazine-2,3-dicarboxylate, pyz = pyrazine) possessing kinetic quantum sieving effect on H 2 /D 2 separation was selected to prepare two new chromatography stationary phase materials CPL-1@γ-Al 2 O 3 and MnCl 2 @CPL-1@γ-Al 2 O 3 by loading CPL-1 on γ-Al 2 O 3 particles with size 80–100 mesh through repeating in situ crystallization process , and afterwards by loading MnCl 2 on CPL-1@γ-Al 2 O 3 via impregnation approach. The two optimized materials were thoroughly characterized by IR, XRD , SEM, EDS and TG/DTA method. The experimental results showed that, under liquid nitrogen temperature by using just 1-m chromatographic column and cheap He gas as carrier gas, the MnCl 2 @CPL-1@γ-Al 2 O 3 can solve the problem of long separation time and trailing phenomenon existing in the CPL-1@γ-Al 2 O 3 column, can realize highly effective hydrogen isotope H 2 /D 2 separation with good separation resolution (R = 1.62) and approximate Gauss distribution of chromatographic peak, can be used for both qualitative and quantitative analysis of hydrogen isotope H 2 /D 2 with short separation time of 6.5 min.
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高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2025
·
IF 8.3
Shibo Wu,Jingrui Cao,Yang Zhou,Jiahao He,Jiangjie Zhou,Muslum Demir,Hongye Yang,Zaizai Tong,Pianpian Ma
High-entropy perovskite oxides, an emerging electrocatalytic electrode material, integrates the distinctive features of high-entropy materials and perovskites, offering significant potential in electrocatalysis. While adjusting the B-site elements has been a widely adopted approach for modulating the electrocatalytic activity of HEPs, there was a notable lack of systematic investigations into the role of A-site ions in regulating their electrocatalytic performance. To overcome this deficiency, in the present study, La 1-x Na x (CrMnFeCoNi) 1/5 O 3 HEPs were synthesized using carbon nanotubes-based sacrificial template method. It was found that the Na substitution at the A-site not only significantly reduced the synthesis temperature but also facilitated the preservation of carbon nanotubes. This retention contributed to the formation of a three-dimensional network structure, exposing a greater number of active sites. The Na modification induced significant valence fluctuations at the B-site and tailored the oxygen vacancy concentrations, enhancing the synergistic "cocktail effect" among the various metal atoms. Furthermore, the introduction of Na stimulated the formation of surface M-OOH species, which serve as active intermediates to enhance OER activity. As a result, the Na-modified HEPs demonstrated exceptional OER performance compared to their parent phases. Among these, La 0.6 Na 0.4 (CrMnFeCoNi) 1/5 O 3 (L6N4-5M) sample exhibited a lower overpotential of 313 mV at a current density of 10 mA cm −2 and a Tafel slope of 47.4 mV dec −1 . Additionally, the A-site Na modification strategy and the in-depth investigation of the OER mechanism provide valuable insights for the future design and development of high-performance HEP electrocatalysts.
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产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2025
·Vol. 36
·期 1
·1-10
·
IF 4.5
Ren Haiyong,Guo Qiaofeng,Lin Bingyuan,Liu Yiyang,Wang Xiang,Huang Kai,Wu Kaiting
Polymer nanocomposites have prolific applications in the environmental and health domain. Healthcare workers have constantly faced a challenge in constructing an effective sustained-release system for drugs, especially in areas where it is difficult to follow traditional treatment guidelines. To achieve a dual sustained release of vancomycin and cell growth factors, we designed a composite hydrogel, which was polymerized under ultraviolet irradiation to form a methacrylate gelatin (GelMA)/polyethylene glycol diacrylate (PEGDA) cross-linked system. The hydrogel showed antibacterial and pro-osteogenic differentiation activities by blending it with vancomycin and insulin-like growth factor 1 (IGF-1)-loaded silica particles. The experimental results showed that with increased PEGDA concentration, the hydrogels were degraded by swelling with a longer sustained release time. After 144-h immersion, the hydrogel still showed sustained release of IGF-1. The antibacterial experiment showed that the hydrogel pair had an obvious antibacterial effect against S. aureus. The results of live/dead staining and Cell Counting kit-8 assay indicated excellent biocompatibility of the hydrogel. Alizarin Red staining (ARS) further demonstrated that this hydrogel could induce bone marrow stem cells to initiate osteogenic differentiation. This hydrogel material exhibited excellent antibacterial and pro-osteogenic differentiation properties and might be promising for chronic osteomyelitis treatment. Graphical
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Tiankai Bai,Zhilong Shi,Shuguang Bao,Xiaorong Hou,Yuping Zhao,Wai L.W. Leung,Yuhui Li,Sirigunqiqige Pan,Ying Xin,Ye Luo,Xiaohe Xiao,Laxinamujila Bai,Huifang Li
Radix Fici Hirtae (RFH), a traditional Chinese medication, is said to be useful in controlling immunity. However, it remained unclear whether its polysaccharides components are associated with these immunomodulatory properties. Herein, two polysaccharides, designated RFHP-1 and RFHP-2, were isolated from RFH using water-soluble alcohol precipitation and column chromatography. Structural characterization by monosaccharide content analysis, methylation, and nuclear magnetic resonance spectroscopy (NMR) revealed that the main chain of RFHP-1 was formed by the interconnection of →4)-α-D-Glc p -(1→, →3,6)-β-D-Glc p -(1→, →3)-β-D-Glc p -(1→, and →4,6)-α-D-Glc p -(1→, and the main chain of RFHP-2 was formed by the interconnection of →4)-α-D-Glc p -(1→, →3,6)-β-D-Gal p -(1→, →3)-β-D-Gal p -(1→, →4,6)-α-D-Glc p -(1→ and →6)-β-D-Gal p -(1→. Both RFHP-1 and RFHP-2 raised the CD4/CD8 ratio and improved the expression of immune factors in immunocompromised mice. By activating the NF-κB pathway (promote phosphorylation of p65 and IκB), RFHP-1 and RFHP-2 both promoted release cytokines (NO, TNF-a, IL-6, and IFN-γ) at RAW 264.7 macrophages. The results of molecular docking (−8.4 kcal/mol vs. -6.0 kcal/mol) and isothermal titration calorimetry (ITC) (−7.75 kcal/mol vs. -7.46 kcal/mol) demonstrated that RFHP-1 exhibited stronger binding affinity with MD2, suggesting greater immunoactivating potential. These findings indicate that RFHP polysaccharides, particularly RFHP-1, may serve as promising candidates for development as dietary supplements for individuals with compromised immune systems.
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产品关联
DOI
PubMed
高影响因子
HISTOCHEMISTRY AND CELL BIOLOGY
·
2025
·Vol. 163
·期 1
·1-15
·
IF 2.1
Zhong Wen-Jing,Xiong Jian-Bing,Zhang Chen-Yu,Jin Ling,Yang Nan-Shi-Yu,Sha Han-Xi,Liu Yu-Biao,Duan Jia-Xi,Guan Cha-Xiang,Zhou Yong,Su Feng
Pulmonary fibrosis (PF) is an insidious, progressive, and fatal age-associated disease that occurs primarily in older adults and has a poor prognosis. Alveolar epithelial cell (AEC) senescence is the critical pathological mechanism of PF. The accumulation of oxygen radicals, commonly referred to as reactive oxygen species (ROS), strongly contributes to cellular senescence. The triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recognition receptor. Triggering via TREM-1 results in ROS, leading to the amplification of inflammation. However, whether TREM-1 is involved in PF by inducing oxidative stress to exacerbate AEC senescence remains unclear. We first observed that blockade of TREM-1 during the fibrotic phase attenuated bleomycin (BLM)-induced PF in mice, with decreased expression of senescence-related proteins, including p16, p21, p53, and γ-H2AX, in the lung tissue. Moreover, TREM-1 blockade during the fibrosis stage restored antioxidant levels by increasing the percentage of Nrf2- and HO-1-positive cells in mice with PF. Notably, TREM-1 was highly expressed in surfactant-associated protein (SPC)-positive AECs in mice with PF. In vitro, blocking TREM-1 activated Nrf2 antioxidant signaling, thereby decreasing intracellular ROS levels and diminishing BLM-induced senescence in AECs. Furthermore, inhibition of Nrf2/HO-1 partially counteracted the anti-senescence effect of blocking TREM-1 in BLM-treated AECs. In this study, we reported that TREM-1 stimulated the senescence of AECs, induced ROS and exacerbated PF. We also provide compelling evidence suggesting that the Nrf2/HO-1 signaling pathway underpins TREM-1-triggered senescence. Therefore, our findings provide new insights into the molecular mechanisms associated with TREM-1 and AEC senescence in the pathogenesis of PF.
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产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Jing Bai,Wencheng Chen,Freeman Bwalya Kabwe,Xutao Shang,Guozhen Lin,Qian Jiang,Chenguang Wang
Amid growing global energy demands and the imperative to reduce carbon emissions, sustainable aviation fuel (SAF) production via Fischer–Tropsch (FT) synthesis has emerged as a pivotal solution. This study focuses on enhancing the selectivity of C8–C16 hydrocarbons for jet fuel through the integration of mesopore confinement effects and acid hydrocracking by developing novel Co/M-TUD-1 catalysts with a uniform, continuous three-dimensional mesoporous architecture. Utilizing sol–gel and melt infiltration methods for catalyst preparation and incorporating metals such as Al, Zr, La, and Ce, we explored how different supports influence FT synthesis outcomes. Characterization techniques, including N2 physisorption, H2-TPR, XRD, NH3-TPD, and Py-FTIR, were employed to understand the physicochemical properties of these catalysts. Experimental results demonstrated significant improvements in jet fuel selectivity, achieving up to 51.3% selectivity and a productivity of 174.7 g/kgcat/h with the Co/Al-TUD-1 catalyst. Further optimization through adjustment of reaction conditions confirmed the potential for industrial-scale SAF production, offering a cleaner, more sustainable approach to addressing fossil fuel shortages.
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产品关联
DOI
高影响因子
JOURNAL OF COORDINATION CHEMISTRY
·
2018
·
IF 1.703
Kuan-Guan Liu,Ru Wang,Hong-Yan Han,Qi-De Shan,Jing Nie,Xiao-Wei Yan
Incorporating ferrocenecarboxylato(-1) into [CuI
2(μ-dppm)2]2+ (dppm = bis(diphenylphosphino)methane) led to the isolation of a heterometallic complex [Cu2(μ2-η1,η1dppm)2(μ2-η1, η1FcCOO)(CH3CN)]BF4·CH3CN (1). It was characterized by infrared spectroscopy (IR), elemental analysis (EA), powder X-ray diffraction analysis (PXRD), ultraviolet–visible spectrum (UV–Vis), nuclear magnetic resonance (NMR), and thermogravimetric analysis (TGA). Single-crystal X-ray structural analysis revealed that ferrocenecarboxylato(-1) coordinated to the [Cu2(μ2-η1,η1dppm)2]2+ unit via μ2-η1,η1 bridging mode in 1. The title complex shows good optical absorption and thermal stability, and reliable electrochemical stability. Moreover, this heterometallic copper(I) complex could be used as a promising electrochemical sensing material for the detection of H2O2.
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高影响因子
危险品化学品经营许可证（带存储）