APPLIED CATALYSIS B-ENVIRONMENTAL
·
2020
·
IF 16.683
Weiming Xiang,Qiuyi Ji,Chenmin Xu,Yang Guo,Yazi Liu,Dunyu Sun,Wenwu Zhou,Zhe Xu,Chengdu Qi,Shaogui Yang,Shiyin Li,Cheng Sun,Huan He
A novel Co 3 O 4 /g-C 3 N 4 /Bi 2 O 2 CO 3 (BCCN) photocatalyst with p-n/n-n heterojunction was synthesized through a solvent-thermal method. The degradation efficiency of 20 mg/L iohexol reached 94 % in 60 min ( k app =0.0417 min −1 ) in BCCN/light/PS system, which was 2.8 and 6.5 times higher than systems of BCCN/light ( k app =0.0150 min −1 ) and BCCN/PS ( k app =0.0064 min −1 ). The g-C 3 N 4 addition lowered conduction band of the prepared material to produce superoxide radicals, activate persulfate and further prevent the recombination of photoelectrons and holes. Superoxide radicals and singlet oxygens were dominant radicals for iohexol degradation. Besides, persulfate could act as electron acceptor to enhance efficiency of electron transfer. The interaction between sulfate, superoxide and hydroxyl radicals improved singlet oxygens production. Furthermore, theoretical calculation and liquid chromatography mass spectrometry were performed to analyze degradation pathway of iohexol in the system. Ultimately, the BCCN/light/PS system can provide a new method to degrade organic pollutants in aquatic environments.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2020
·
IF 4.939
Fanghui Wang,Yajun Zhang,Yimeng Luo,Yanan Wang,Hong Zhu
A dandelion-like CNTs-Ni foam composite carrier supported Co–Mo–P ternary alloy catalyst (Co–Mo–P/CNTs-Ni foam) was prepared by electroless plating . The structure of Co–Mo–P/CNTs-Ni foam catalyst is characterized by XRD , SEM, XPS and EDS . The particle size of Co–Mo–P ternary alloy nanoparticles is about 80 nm. The Co–Mo–P/CNTs-Ni foam completely retains the tubular structure of carbon nanotubes and the gaps between carbon nanotubes of CNTs-Ni carrier, which increases the specific surface area of the catalyst and the flow space of reactants and products. Co–Mo–P/CNTs-Ni foam catalyzes sodium borohydride alcoholysis to produce hydrogen at a maximum rate of 2.64 L ·min −1 ·g −1 , and the reaction activation energy is 47.27 kJ ·mol −1 , which is far lower than that of the spontaneous alcoholysis reaction of sodium borohydride. After the Co–Mo–P/CNTs-Ni foam catalyst was reused 8 times, the catalytic hydrogen production rate was reduced by 23% compared with the initial rate.
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION SCIENCE AND TECHNOLOGY
·
2020
·
IF 1.718
Yingying Li,Haoliang Zhao,Weijun Yang,Yong Gao,Liming Wang
Trace cobalt ion in the zinc sulfate electrolyte is the most difficult to be removed among all metallic impurities and has the most detrimental effect on zinc electrowinning. In this study, poly(p-hydroxystyrene) resin was first prepared from polystyrene, and then 1-nitroso-2-naphthol was grafted onto poly(p-hydroxystyrene) resin through -O- group by a series of reactions to obtain the 1-nitroso-2-naphthol-grafted-poly(p-hydroxystyrene) resin. Finally, the grafted resin was supported on SiO2. The supported resin could removal trace cobalt ions with good selectivity and reusability in the zinc sulfate leachate, which can meet the requirements of the industrial electrolytic zinc process.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ETHNOPHARMACOLOGY
·
2020
·
IF 3.69
Diao Hui,Tan Rui-Zhi,Li Jian-Chun,Zhong Xia,Wen Dan,Fan Jun-Ming,Wang Li
Ethnopharmacological relevance Acute kidney injury (AKI) is a common disease in hospitalized patients, especially in critically ill patients. It is characterised with high morbidity and mortality, and is also an important cause of chronic kidney disease and chronic renal failure. Astragalus propinquus Schischkin and Panax notoginseng (A&P) compound, a famous traditional Chinese medicine , consists of Astragalus propinquus Schischkin, Panax notoginseng, Angelica sinensis , Achyranthes bidentata , and Ecklonia kurome, has been widely used for the treatment of various kidney diseases in the southwest of China. However, the effects of A&P on treatment of AKI and its underlying mechanism are needed to be uncovered. Aim of the study Recent researches reported that Mincle (Macrophage-inducible C-type lectin) plays a key role in renal injury of AKI by regulating the expression and secretion of inflammatory cytokines on macrophage through modulating NF-κB signaling pathway. Here, we aimed to investigate the renoprotective effect of A&P on AKI and whether by inhibiting Mincle. Materials and methods We established a lipopolysaccharide (LPS)-induced Bone Marrow-Derived Macrophage (BMDM) inflammatory cell model and a cisplatin-induced mouse AKI model in vitro and in vivo . Renal histopathology staining was performed to observe kidney morphology. The expression and secretion of inflammatory cytokines were detected by real-time PCR and Enzyme-linked immunosorbent assay. Western blotting was used to detect the protein levels and Flow cytometry performed to detect polarization of macrophage. Results The results showed that A&P significantly reduced the mRNA expression of IL-1β, IL-6, TNFα and MCP-1 in LPS-stimulated BMDM cells, and secretion of IL-1β and IL-6 in supernatant. The same results were found in Cisplatin-induced AKI kidney and serum after treatment with A&P. The data also showed that A&P strongly reduced the mRNA and protein levels of Mincle in vitro and vivo , and also inhibited the activation of Syk and NF-κB. Notably, A&P down-regulated the M1 macrophage marker iNOS, which may relate to the inhibition of Mincle. Interestingly, both overexpression of Mincle by transfection of pcDNA3.1-Mincle plasmid and administration of TDB (a ligand of Mincle) can significantly abolished the A&P-inhibited inflammation in BMDM, suggesting Mincle pathway play a key role in macrophage inflammation in AKI. Conclusion Our findings indicated that A&P protected kidney from inhibiting inflammation through down-regulating of Mincle pathway in macrophage in AKI. It provides a potential medicine compound for the treatment of AKI.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2020
·
IF 6.215
Silu Huo,Yubo Zhao,Mingzhu Zong,Bolong Liang,Xueli Zhang,Izhar Ullah Khan,Kexun Li
Heteroatom-doped porous carbon frameworks have attracted extensive attention as high-performance electrodes for capacitive applications. While their further development is still restricted by the inevitable concurrent dopant leaching effect and structural collapse during the high-temperature pyrolysis process . Therefore, developing a straightforward method for the synthesis of carbons simultaneously with plentiful multiple external defects and rational porous structure to satisfy high-performance capacitive applications is still a tremendous challenge. Herein, an emerging plerogyra sinuosa-like hierarchically porous carbon with plentiful N/P external defects is firstly prepared via an effective and in-site carbonization process, which shows great promise for supercapacitor and capacitive deionization applications. Due to the efficient N and P synergistic effects and 3D connected framework with prolific meso-microporous structure, the optimized carbon exhibits a large specific capacitance of 337 F g −1 at a current density of 1 A g −1 and maintains 239 F g −1 at 100 A g −1 in 6.0 M KOH electrolyte. For capacitive deionization tests, the carbon shows an excellent salt adsorption capacity of 19.3 mg g −1 in NaCl solution with a concentration of 500 mg L −1 at an applied voltage of 1.2 V. While from the kinetics analysis and density functional theory, we find that the coupling of multiple external defects has a positive influence on the distribution of electron density and surface condition, which is greatly beneficial to pseudocapacitance, quantum capacitance and the electrolyte-adsorption capacity. This work provides a new route for the preparation of emerging heteroatom-doped hierarchically porous carbon frameworks for further advanced applications such as water treatment, electrocatalysis , as well as energy storage.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2020
·
IF 5.065
Yanqing Wang,Qianqian Han,Hongmei Zhang,Yuanyuan Yan
In this work, the binding interactions of norfloxacin (NRF) with p -acetylaminophenol (AAP), aspirin, ibuprofen , and aminopyrine were investigated by molecular modeling and fluorescence quenching methods. The results indicated the existence of the electrons transferring during the π–π stacking interaction with face to face stacking of them. NRF acts as electron acceptor during the NRF-AAP and NRF-aminopyrine complexes and acts as electron donor during the NRF-aspirin, NRF-ibuprofen complexes. Fluorescence quenching of NRF induced by AAP, aspirin, ibuprofen, and aminopyrine are the formation of complexes. The binding ability of NRF with AAP, aspirin, ibuprofen, and aminopyrine indicated that the order are from top to bottom aminopyrine, AAP, aspirin, and ibuprofen and the number of the binding site n is about 1.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2021
·Vol. 9
·期 30
·9599-9609
·
IF 7.393
Cong Shen,Yanqing Zhu,Zixiao Li,Jingling Li,Hong Tao,Jianhua Zou,Xueqing Xu,Gang Xu
InP quantum dots (QDs) are considered as the most promising alternative to Cd-based QDs with lower toxicity, and emission spectrum tunability ranging from the visible to near-infrared region. Although high-quality fluorescent InP QDs have been successfully synthesized by several groups, the rigorous synthesis conditions hinder its practical use in display devices. In this work, for the first time, we introduce Zn2+ into the growth stage of the InP QDs to prepare an InP–In(Zn)P core, and then the as-grown InP–In(Zn)P cores were consecutively coated with typical double shells of inner ZnSe and outer ZnS. The final InP–In(Zn)P/ZnSe/ZnS core/shell/shell QDs exhibited a maximum photoluminescence (PL) quantum yield (QY) of 94.3% and have tunable emissions from yellow (569 nm) to red (630 nm), showing a potential application in display devices. Above all, compared with other related studies, the excellent PL properties were obtained in relatively milder conditions (ultimate vacuum level of 400 mTorr). The results of this study provide guidance for the commercial application of InP QDs as a viable alternative to Cd-based QDs.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Zhaode Mu,Jiangman Tian,Jie Wang,Jing Zhou,Lijuan Bai
Sensitive detection of endotoxin is especially critical in the fields of food security, therapeutics and medical science. In this work, a new sandwich-type electrochemical aptasensor was designed for ultrasensitive detection of endotoxin. For the first time, nitrogen-doped carbon nanotubes (N-CNTs) was functionalized with polydiallyldimethylammonium chloride (PDDA), forming P-N-CNTs nanocomposite. Then, Fe-based metal–organic framework (Fe-MOF) and silver nanoparticles (AgNPs) was decorated with P-N-CNTs to form the MOF/Ag-P-N-CNTs nanohybrid, which was employed as an enhanced signal indicator, not only exhibited outstanding electrochemical activity, but also could directly label with thiol-modified signal probes (TSPs) to form tracer label. Additionally, the avidin–biotin recognition system was introduced to increase the amount of biotin-modified capture probes (BCPs). Differential pulse voltammetry (DPV) was utilized to investigate the detection performances of the proposed aptasensor, which suggested a wide linear range from 1 fg/mL to 100 ng/mL with a low detection limit of 0.55 fg/mL toward endotoxin.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2019
·
IF 3.206
Guohan Sun,Shiqiao Wang,Jianfeng Zhou,Jianbin Pan,Yanli Tong,Qinghua Mei,Haiyun Zhai
In the present study, a novel and facile poly-m-amino-benzenesulfonic acid (p-m-ABSA) film on glassy carbon electrode (GCE) was developed using pulse potentiostatic method (PPM), which is employed with the oxidative polymerization of m-ABSA at anode potential. Meanwhile, a simple and sensitive sensor was fabricated to detect normetanephrine (NMN), which is one of the significant diagnostic markers for diseases. Compared with bare GCE, the p-m-ABSA film prepared on GCE surface has the advantage of increasing electrode surface area and active sites distinctly, thus obviously improving the electrocatalytic activity. The results demonstrated that the developed electrochemical sensor exhibited high sensitivity, stability, selectivity and excellent electrocatalytic activity towards NMN. The surface morphology of p-m-ABSA/GCE was characterized by scanning electron microscopy (SEM), indicating that the electrode surface had a layered structure. The preparation conditions and analysis methods of sensors were studied in detail. Under optimum conditions, peak current and concentrations of NMN were linearly related well from 0.5 to 30.0 µM with a limit of detection (S/N = =3) of 0.17 µM. Moreover, this modified sensor has also been successfully used for the detection of NMN in human serum samples.
✓ 已验证
产品关联
DOI
高影响因子
PEST MANAGEMENT SCIENCE
·
2019
·Vol. 75
·期 12
·3175-3183
·
IF 3.255
Ning Zhao,Lu'an Ge,Yanyan Yan,Shuang Bai,Dandan Wang,Weitang Liu,Jinxin Wang
BACKGROUND Asia minor bluegrass ( Polypogon fugax Nees ex Steud.) is an invasive grass species severely infesting wheat and canola fields in China. In May 2017, a suspected resistant P. fugax population AHHY that survived fenoxaprop- P -ethyl applied at its field-recommended rate was collected from a wheat field in Huaiyuan County, Anhui Province, China. This study aimed to determine the resistance profile of AHHY to acetyl-CoA carboxylase (ACCase) inhibitors and to investigate its mechanisms of resistance to fenoxaprop. RESULTS Single-dose testing indicated that the AHHY population had evolved resistance to fenoxaprop. The partial carboxyltransferase domain of ACCase in P. fugax was amplified and compared. Four loci encoding plastidic ACCase were isolated from both the resistant and sensitive individuals. Combining gene sequencing with the derived cleaved amplified polymorphic sequence assay, we found that 100% of the plants of AHHY carried Trp-1999-Ser mutation in their ACCase1,1–2 allele. Whole-plant dose–response bioassay indicated that AHHY was highly resistant to fenoxaprop and pinoxaden (resistance index (RI) ≥ 10) with low resistance to clodinafop-propargyl, sethoxydim, and clethodim (2 ≤ RI < 5). Pre-treatment with piperonyl butoxide largely reduced (55%) the weed's resistance to fenoxaprop. Both basal and fenoxaprop-induced glutathione S -transferases activities toward 1-chloro-2, 4-dinitrobenzene were significantly higher in resistant plants than in susceptible plants. CONCLUSION This study revealed that P. fugax had multiple alleles encoding plastidic ACCase, and reported for the first time the occurrence of Trp-1999-Ser mutation and non-target-site resistance in this species. Fenoxaprop resistance in AHHY plants was conferred by target-site mutation and P450s-involved enhanced metabolism. © 2019 Society of Chemical Industry
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemical Science
·
2019
·Vol. 10
·期 35
·8179-8186
·
IF 9.556
Xiaohong Pan,Yuehui Zhao,Tingting Cheng,Aishan Zheng,Anbin Ge,Lixin Zang,Kehua Xu,Bo Tang
Reductive stress, the opposite of oxidative stress, represents a disorder in the redox balance state which is harmful to biological systems. For decades, the role of oxidative stress in tumor therapy has been the focus of attention, while the effects of reductive stress have been rarely studied. Here, we report the anti-cancer effects of reductive stress induced by three natural antioxidants (resveratrol, curcumin and celastrol). Considering the fact that the solid tumor microenvironment suffers from hypoxia, we performed cell experiments under hypoxic conditions. In order to observe the reductive stress, we first developed an ultrasensitive fluorescent probe (TCF-MQ) for specifically imaging NAD(P)H which is a marker of reductive stress. TCF-MQ responded to NAD(P)H rapidly and exhibited high sensitivity with a detection limit of 6 nM. With the help of TCF-MQ, we found that upon the treatment of HepG2 cells with pharmacological doses of three natural antioxidants under hypoxic conditions, high levels of NAD(P)H were produced before cell death. The excess NAD(P)H resulted in reductive stress instead of oxidative stress. In contrast, under normoxic conditions, there was no reductive stress involved in the process of cell death induced by three natural antioxidants. Therefore, we hypothesize that the mechanism of cancer cell death induced by natural antioxidants under hypoxia should be attributed to the reductive stress.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2019
·
IF 9.518
Xin Zhang,Guoming Xie,Dan Gou,Peng Luo,Yuan Yao,Hui Chen
Pseudomonas aeruginosa ( P. aeruginosa ) is one of the most intractable multidrug-resistant bacteria of nosocomial infections. The conventional detection methods for P. aeruginosa are time-consuming or low detection sensitivity. Here, a novel enzyme-free electrochemical biosensor was constructed to detect P. aeruginosa rapidly and sensitively. Firstly, the ZrMOF with large surface area was synthesized, which offers excellent adsorption. Further, it was connected with a specific amount of Cu 2+ to synthesize Cu-ZrMOF with high catalytic activity . Then the [email protected] @DNA nanocomposite was composed and served as the signal probe to catalyse the decomposition of H 2 O 2 . Moreover, high conductive Super P was introduced to increase the electron transfer for satisfactory detection sensitivity. The proposed biosensor was constructed and used to quantify P. aeruginosa with a wide linearity range of 10–10 6 CFU mL −1 and a low limit of detection of 2 CFU mL −1 (S/N = 3). Compared with conventional methods, the new method of present biosensor is more sensitive, and less time-consuming (only within 120 min). The analytical performance evaluation indicated that the biosensor exhibits good reproducibility and specificity. Finally, the biosensor was successfully applied to quantify P. aeruginosa in spiked urine samples. These results show that the proposed electrochemical biosensor might be a potential laboratory tool for detecting P. aeruginosa in the clinic.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）