Nature Nanotechnology
·
2025
·
IF 34.9
Liang Kaiyu,Zhao Lan,Zhang Shuheng,Zheng Luyu,Zhang Zheyuan,Wang Shengyu,Chen Junxin,Xu Wenbin,Wang Weikai,Yang Hanshen,Song Chenxin,Qiu Pengcheng,Zhao Chenchen,Fang Weifeng,Zhu Jinjin,Fan Shunwu,Liu Zhaoming,Tang Ruikang,Zhao Yueqi,Fang Xiangqian
In the elderly population, dysregulated cellular behaviour during the healing process impacts tissue regeneration after injury. Early in the regeneration process, pro-inflammatory macrophages contribute to immune imbalance, while in later stages, senescent stem cells reduce regenerative capacity. Here we demonstrate that nicotinamide adenine dinucleotide (NAD + ) can reprogramme both types of dysfunctional cell. We developed a spatiotemporal-adaptive nanotherapeutic system for the delivery of NAD + into selected cells during different phases of tissue repair. By replenishing intracellular NAD + pools, this system reshapes the multicellular regeneration niche, by metabolically rewiring pro-inflammatory macrophages towards a pro-repair phenotype during the early phase, and enhancing the differentiation capacity of senescent stem cells at later stages. This strategy effectively restored impaired bone regeneration in osteoporotic mice and accelerated skin wound healing. Our work presents a spatiotemporal-adaptive nanomedicine platform that bridges cell metabolism, nanomedicine and regeneration therapy.
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DOI
PubMed
高影响因子
Nature Photonics
·
2025
·
IF 32.9
Zhang Jiakang,Yan Wenjian,Li Zhipeng,Jiang Haokun,Peng Cheng,Lan Mengjiao,Sun He,Yang Jinxian,Wang Yanbo,Li Chongwen,Pang Shuping,Zhou Zhongmin
The commercialization of perovskite photovoltaics faces significant hurdles due to device degradation under environmental stressors, such as illumination, humidity and heat, which represents a core challenge for industrial applications. Here we present a conformational engineering strategy targeting the buried interface of perovskite solar cells and based on the structural evolution of additives—from 1,1-diphenylethylene to 1-octyl-2-(1-phenylvinyl)benzene and diethylamino hydroxybenzoyl hexyl benzoate. We decouple the contributions of the additives, including ultraviolet shielding, strain regulation and chemical passivation. In conjunction with in situ characterization, we reveal that dynamic interfacial strain regulation plays a major role in improving device stability during light–dark cycling. Our devices achieve power conversion efficiencies of 26.47% and 22.67%, for active areas of 0.09 cm 2 and 20.5 cm 2 , respectively. Under maximum power point tracking, small-area devices maintain 96.2% of their initial power conversion efficiency after 1,132 h of testing in ISOS-L-1I (continuous illumination) and 88.8% after 348 h in ISOS-LC-1 (12-h day–night cycling). This research establishes an innovative design paradigm for stable and efficient perovskite solar cells through a multifunctional strategy driven by conformational engineering.
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DOI
高影响因子
Nature Photonics
·
2025
·
IF 32.9
Gao Yuping,Liu Hang,Song Zonglong,Chen Yu,Yang Liu,Hu Ziyang,Zou Yu,Chen Yongsheng,Liu Yongsheng
Achieving uniform crystallization across both top and buried interfaces in perovskite films is crucial for unlocking their full photovoltaic potential, yet remains an unresolved challenge. The buried interface, in particular, suffers from poor crystallization relative to the top surface, resulting in suboptimal crystal quality and increased defect densities. Here we propose a one-step strategy to induce the spontaneous formation of near-phase-pure two-dimensional perovskites at the buried interface via the introduction of organic cation halide salts in the perovskite precursor solution. Single-crystal structure analysis highlights the pivotal role of molecular engineering in facilitating the spontaneous formation of buried two-dimensional perovskite phases. The low dipole moments and planar rigidity structures of organic spacers promote their aggregation at perovskite grain boundaries, followed by their migration to the film’s bottom interface. The two-dimensional perovskite layer simultaneously promotes uniform crystallization and efficient defect passivation at the buried interface, leading to a power conversion efficiency of 26.31% (certified 26.02%). Unencapsulated devices retain 95% of their initial power conversion efficiency after 1,000 hours of continuous illumination.
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高影响因子
Nano-Micro Letters
·
2024
·Vol. 17
·期 1
·1-18
·
IF 31.6
Yu Ming-Yuan,Wu Jing,Yin Guang,Jiao Fan-Zhen,Yu Zhong-Zhen,Qu Jin
A flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane is designed for synergistic solar-thermal desalination of seawater/brine and catalytic degradation of organic pollutants.
The hydrogen bonding networks can be regulated by the abundant surface –OH groups and the in situ generated ions and radicals during the degradation process for promoting solar-driven steam generation.
The de-solvation of solvated Na + and subsequent nucleation/growth of NaCl are effectively inhibited by SO 4 2− /HSO 5 − ions.
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高影响因子
Science China-Materials
·
2023
·Vol. 67
·期 1
·162-169
·
IF 8.1
Yang Bixia,Zhu Mengyao,Jiang Xingpeng,Shao Wenlei,Wang Zhiqi,Yan Jiawei,Zheng Yanting,Zhuang Zanyong,Yu Yan
The photooxidation of renewable bioderivatives into value-added chemicals is highly significant; however, it typically exhibits low selectivity owing to the challenges in controlling the oxidative species and managing the desirable reaction pathways. In this work, we used the Bi 2 O 2 CO 3 /ZnIn 2 S 4 heterostructure, prepared by a CO 2 -mediated solid–solid phase transition, to catalyze the photooxidation of bioderived 5-hydroxymethylfurfural (HMF) into 2,5-diformylfuran (DFF) with a high selectivity of 98.1% and a yield rate of 882.6 µmol g −1 h −1 . The metal carbonate/oxide heterointerface enables the effective transfer of photoactive electrons and holes, optimizes surface oxygen activation, and facilitates the synergy of ·OOH and holes to selectively convert HMF into DFF. The findings unravel how the tailoring and coupling of the electron–hole pairs and reactive oxygen species on heterostructured materials can promote the usage of renewable feedstocks for sustainable development.
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高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 7
·11214-11227
·
IF 0
Li Tiantian,Yang Huan,Zhang Naili,Dong Lijia,Wu Aiping,Wu Qiqian,Zhao Mingshui,Liu Hua,Li Yan,Wang Yanhong
Cadmium (Cd) contamination is a widespread environmental issue. There is a lack of knowledge about the impacts of applying arbuscular mycorrhizal fungi (AMF) and biochar, either alone or in their combination, on alleviating Cd phytotoxicity in Ligustrum lucidum . Therefore, a pot experiment was conducted in a greenhouse, where L. lucidum seedlings were randomly subjected to four regimes of AMF treatments (inoculation with sterilized AMF, with Rhizophagus irregularis , Diversispora versiformis , alone or a mixture of these two fungi), and two regimes of biochar treatments (with or without rice-husk biochar), as well as three regimes of Cd treatments (0, 15, and 150 mg kg −1 ), to examine the responses of growth, photosynthetic capabilities, soil enzymatic activities, nutritional concentrations, and Cd absorption of L. lucidum plants to the interactive effects of AMF, biochar, and Cd. The results demonstrated that under Cd contaminations, AMF alone significantly increased plant total dry weight, soil pH, and plant nitrogen (N) concentration by 84%, 3.2%, and 13.2%, respectively, and inhibited soil Cd transferring to plant shoot by 42.2%; biochar alone significantly enhanced net photosynthetic rate, soil pH, and soil catalase of non-mycorrhizal plants by 16.4%, 9%, and 11.9%, respectively, and reduced the soil Cd transferring to plant shoot by 44.7%; the additive effect between AMF and biochar greatly enhanced plant total dry weight by 101.9%, and reduced the soil Cd transferring to plant shoot by 51.6%. Furthermore, dual inoculation with D. versiformis and R. irregularis conferred more benefits on plants than the single fungal species did. Accordingly, amending Cd-contaminated soil with the combination of mixed-fungi inoculation and biochar application performed the best than either AMF or biochar alone. These responses may have been attributed to higher mycorrhizal colonization, soil pH, biomass accumulation, and biomass allocation to the roots, as well as photosynthetic capabilities. In conclusion, the combined use of mixed-fungi involving D. versiformis and R. irregularis and biochar addition had significant synergistic effects on enhancing plant performance and reducing Cd uptake of L. lucidum plants in Cd-contaminated soil. Graphical abstract
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WATER AIR AND SOIL POLLUTION
·
2024
·Vol. 235
·期 2
·1-18
·
IF 3.8
Deng Yu,Chen Jingfan,Xiao Zhidan,Liu Jiaying,Zhang Jie,Zhu Bingqi,You Xiaotong,Ni Fuquan,Ao Tianqi,Tan Yanping
N self-doped porous biochars (KBCs) were synthesized through high-temperature carbonization and KHCO 3 activation using chicken feathers as biomass. Subsequently, it was employed for the remediation of tetracycline hydrochloride (TC)-contaminated water and soil. The properties of KBCs were analyzed by various characterization techniques. The results verified that KBC 800-2 exhibited outstanding specific surface area (1648.89 m 2 g −1 ) and pore volume (0.806 cm 3 g −1 ). The maximum adsorption capacity of KBC 800-2 for TC was 147.8 mg g −1 , which was superior to that of raw biochar (15.5 mg g −1 ). The results of pseudo-second-order and Freundlich indicated that the process was dominated by chemisorption. Moreover, the adsorption capacity of KBC 800-2 was stable over a wide pH range of 3–12 and high coexisting ionic strength. The consequences proved that the enhancement of pore filling effect and π-π electron interactions between TC and N self-doped adsorbent were the predominant driving forces to improve the adsorption efficiency of TC. Notably, compared to T50 (soil and 50 mg kg −1 TC), the properties of organic carbon, total nitrogen, and sucrase, urease, and catalase activities in TKBC 800-2 (soil, 50 mg kg −1 TC, and 2% KBC 800-2 ) were increased by 108.57%, 4.98%, 886.08%, 89.52%, and 78.08% respectively. KBC 800-2 as a low-cost and highly effective adsorbent for antibiotic pollution has enormous application potential. Graphical
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高影响因子
AMB Express
·
2023
·Vol. 13
·期 1
·1-8
·
IF 3.7
shi Shi,Cheng Yutong,Wang Shuai,Zhang Xiangmei,Han Fubo,Li Xiaojing,Dong Huijun
Nonomuraea gerenzanensis ( N. gerenzanensis ) is known for its ability to biosynthesize A40926, the precursor of the glycopeptide antibiotic (GPA) Dalbavancin. However, challenges and uncertainties related to the genetic manipulation of the rare actinomycetes remain. In order to improve the conjugation transfer of N. gerenzanensis , the crucial factors affecting conjugal transfer were evaluated, including agar medium, mycelial state, donor-recipient ratio, magnesium ion concentration, and antibiotic coverage time firstly. Additionally, γ-butyrolactone (GBL) for quorum sensing (QS) and antibiotics targeting bacterial walls were applied to evaluate their effects on conjugation transfer. As a result, the optimal conditions of 5%TSB of liquid medium, 24 h of the period time, V0.1 of agar medium, 30 mM of magnesium ion, the ratio 10:1 of donor-to-recipient, and 27 h of the overlaying time of antibiotic were determined. Furthermore, the results showed that autoinducer GBL and GPA teicoplanin had a synergetic effect on the conjugation transfer of N. gerenzanensis at a working concentration of 60 µM and 0.5 µg mL −1 , respectively. The highest conjugation efficiency could reach about 1.3 depending on the optimal process conditions and the interference of QS and antibiotics.
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高影响因子
CHINESE SCIENCE BULLETIN
·
2014
·Vol. 59
·期 16
·1794-1799
·
IF 1.365
Yi Min,Shen Zhigang,Zhu Jinyang
A novel fluid dynamics route for scalable and efficient production of graphene and its analogues is demonstrated. Atomic force microscopy and transmission electron microscopy analyses strongly suggest that the bulk layered materials (graphite, BN, MoS 2 , and WS 2 ) are efficiently exfoliated into individual layers containing mono- and few-layer nanosheets. Computational fluid dynamics analysis indicates that multiple fluid dynamics events are responsible for efficient exfoliation. Cavitation and pressure release can generate normal force for exfoliation. The velocity gradient-induced viscous shear stress, the turbulence-induced Reynolds shear stress, and shear effects stemmed from turbulence and flow channel-induced collisions can generate lateral force for exfoliation, resulting in theses bulk layered materials self-exfoliation down to single or few layers through their intrinsically lateral self-lubricating ability.
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高影响因子
CHINESE SCIENCE BULLETIN
·
2007
·Vol. 52
·期 2
·194-199
·
IF 0.722
Wu Hua,Zeng XiangQiong,Lu LingBo,Ren TianHui
Two di-n-butyl dithiocarbamate derivatives were easily synthesized. Their tribological performances as lubricating oil additives in rapeseed oil were evaluated using a four-ball machine, and their chemistry of films was analyzed with X-ray absorption near-edge spectroscopy (XANES). The results indicate that the two compounds possess excellent anti-wear property and good load-carrying capacity. According to the XANES results, for the thermal films, the outer surfaces are mainly composed of N, S-containing polymer and ferric sulfate, and the near-surface and the bulk are composed of ferrous sulfate, while for the anti-wear films, the outer surfaces are only composed of ferric sulfate, but the near-surface and the bulk are mainly composed of ferrous sulfate.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2024
·Vol. 59
·期 10
·4267-4280
·
IF 3.5
Chen Ling,Gan Qingbao,Xiao Xueqing,Cai Shuguang,Yan Xiaohui,Zheng Chan
Recent progress in the development of MnO 2 -based micromotors has shown the immense potential of these motile devices to remediate environmental contamination. However, the production of such micromotors on an industrial scale through a facile, efficient and reproducible process remains challenging. The present work aimed to address this issue using naturally occurring and abundant pine pollen (PP) grains. The immersion of PP in potassium permanganate (KMnO 4 ) solutions was found to generate MnO 2 nanoparticles (NPs) on the PP surfaces, the amount and distribution of which was readily adjusted by varying the coating time. Because of the asymmetrical shape of the PP grains, the MnO 2 /PP composites exhibited rapid self-propulsion at a maximum speed of 360.686 μm/s (approximately eight body lengths/s) in low-concentration hydrogen peroxide (H 2 O 2 ) solutions. The ability of these materials to remediate heavy metal pollutants was also examined and was evidently increased by a factor of 1.5 compared with static counterparts. These composites could also be recovered and reused over three consecutive cycles. The competitive cost, continuous motion and superior decontamination capacity of these materials suggests potential applications in the rapid removal or degradation of heavy metal ions, toxic organic dyes, pathogenic bacteria and other pollutants in wastewater. These micromotors represent a new approach to the utilization of natural materials in environmental remediation.
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高影响因子
Food Production Processing and Nutrition
·
2024
·Vol. 6
·期 1
·1-10
·
IF 4
Liu Hao,Chen Jianan,Dong Meng,Pang Jie,Qin Lei,Huang Xuhui
The aim of this research was to determine the residues of dioxins and dioxin-like polychlorinated biphenyls in cultured eel and find out the source of pollution and the distribution pattern of eels. One hundred samples of eel, 4 fodder samples, and 12 environmental samples (water, plants, and soil) were collected from 4 cities and counties in Jiangxi Province, China. The contents of 17 kinds of dioxins (PCDD/Fs) and 12 kinds of dioxin-like polychlorinated biphenyls (dl-PCBs) were determined by high-resolution gas chromatography-tandem mass spectrometry, and the exposure risk was evaluated by using risk index. The total toxicity equivalence quantity (TEQ) of dioxin and dioxin-like polychlorinated biphenyls in eel and fodder samples collected in the study area were 0.65 ± 0.31 pg/g and 0.10 ± 0.02 pg/g, respectively. Dl-PCBs were the main dioxin pollution in eel and fodder samples. 2,3',4,4',5-pentachlorodiphenyl and 2,3,3',4,4'-pentachlorobiphenyl were the main contributing monomers. The environmental samples were mainly polluted by polychlorinated dibenzo-p-dioxins (PCDDs), with the main contributing monomer being Octachlorodibenzodioxins (OCDD), while 3,3',4,4',5-pentachlorobiphenyl and 2,3,4,7,8-pentachlorodibenzofuran were the main toxic compounds in eel and fodder. The dioxin pollution of eels cultured in Jiangxi Province was mainly from fodder polluted via dl-PCBs. The meat segment VI (tail) exhibited a strong enrichment effect of polychlorinated benzofurans (PCDFs). It should be the key part for dioxins and dioxin-like polychlorinated biphenyls assessment. Further, the results were helpful to improve the edible safety of eel products and the efficiency of the risk assessment of dioxins and dioxin-like polychlorinated biphenyls in fish. Graphical
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高影响因子
危险品化学品经营许可证（带存储）