ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Xingkang Diao,GuoHua Qi,Yu Tian,Jing Li,Yongdong Jin
Hydrogen peroxide (H2O2) is a key reactive oxygen species (ROS) that regulates redox signals in organisms by reversibly oxidizing target proteins. However, it causes oxidative damage at supraphysiological concentrations, leading to various diseases. Therefore, accurate and sensitive detection of H2O2 in organisms, especially in cells, is essential for reliable pathological diagnosis. Herein, a sensitive and reproducible surface-enhanced Raman spectroscopy (SERS) platform was developed for in situ profiling detection of H2O2 released from cells utilizing a uniform and dense plasmonic Ag@Au core/shell nanoparticle nanomembrane (Ag@AuNPs-NM) as the SERS substrate. In the designed substrate configuration, the Ag@Au core/shell nanostructure combines the strong electromagnetic field enhancement of AgNPs with the stability of AuNPs, which could enhance the sensitivity of SERS detection. Meanwhile, the dense and uniform distribution of “hot spots” in the Ag@AuNPs-NM endows the platform with excellent detection reproducibility. In the presence of H2O2, the ratiometric I1073/I998 SERS signal of the Raman reporter 4-mercaptophenylboronic acid (4-MPBA) is changed due to the oxidation of the boronate group of 4-MPBA to the phenolic hydroxyl group of 4-hydroxythiophenol (4-HTP). The developed SERS sensing platform possesses a good linear relationship between the ratiometric I1073/I998 signal of 4-MPBA and the concentration of H2O2 in the range from 1 to 500 μM, with a limit of detection of 0.26 μM. As a proof of concept, we applied this platform to in situ monitoring of drug-stimulated H2O2 released from cells that were cultured on the SERS chips. This work provides a practical method for the in situ profiling detection of cellular H2O2 with satisfactory results, holding promise for the diagnosis of H2O2-associated diseases.
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DOI
PubMed
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2025
·
IF 5.4
Yuxin Song,Huan Xing,Liang Ma,Fengxia Wang,Mingfang Zhang,Zherui Wan,Xuewen Li,Yan Tang,Guang Yang
Heavy metal ions (HMIs) pose a great threat to human health because of their irreversible detrimental effects, thus the fabrication of a convenient sensing platform that is capable of tracing HMIs with high accuracy remains a major challenge. Herein, a portable strategy for the fabrication of electrochemical sensor was described in which Ag-ZIF-8 and polyaniline (PANI) were combined and dropwise to glassy carbon electrode (GCE) for the recognition of Pb 2+ and Cu 2+ by DPSV. The structures and properties of the proposed working electrode (PANI/Ag-ZIF-8/GCE) were studied by TEM, SEM, FT-IR, XRD, CV and DPSV. Additionally, the results revealed that the designed sensing platform of the PANI/Ag-ZIF-8/GCE displayed excellent electrochemical performance for the simultaneous and individual tracing of HMIs including (Pb 2+ and Cu 2+ ) with satisfactory sensitivity and selectivity due to the excellent conductivity of PANI and large surface areas with abundant active sites on Ag-ZIF-8. The LODs for individual recognition of Pb 2+ and Cu 2+ were 0.003 μM and 0.006 μM, respectively. The LODs of simultaneous tracing of Pb 2+ and Cu 2+ were 0.004 μM and 0.008 μM, respectively. Moreover, real sample analysis of tap water and the Songhua River indicated good results with higher reliability for the detection of target HMIs, which may be beneficial for the fabrication of MOF-based probes by a simple strategy for the detection of HMIs to safeguard people’s lives and health.
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DOI
高影响因子
Science China-Materials
·
2016
·Vol. 60
·期 1
·68-74
·
IF 0
Wang Di,Wang Ruihong,Liu Liyuan,Qu Yang,Wang Guofeng,Li Yadong
Techniques for detecting glucose are developing at a breathtaking speed because diabetes mellitus can cause many serious complications, such as blindness, high blood pressure heart disease and kidney failure. Herein, water soluble NaYF 4 :Eu 3+ @Ag core-shell nanocrystals for glucose detection with lower detection limit have been successfully developed, using NaYF 4 :Eu 3+ cores as the energy donors and Ag shells as the efficient quenchers through energy transfer. After immobilization of glucose oxidase (GOx) on the surface of NaYF 4 :Eu 3+ @Ag core-shell nanocrystals, the Ag shells can be decomposed in the presence of glucose, accompanied by down-shifting luminescence recovery. The limit of detection of NaYF 4 :Eu 3+ @Ag was 0.12 μmol L −1 . Therefore, the NaYF 4 :Eu 3+ @Ag can be easily extended to the detection of a variety of H 2 O 2 -involved analytes.
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DOI
ACS Omega
·
2021
·
IF 3.512
Xufei Shao,Xiaotong Li,Jinzhu Ma,Runduo Zhang,Hong He
Ozone is a poisonous gas, so it is necessary to remove excessive ozone in the environment. Catalytic decomposition is an effective way to remove ozone at room temperature. In this work, 10%Ag/nano-Al2O3 and 10%Ag/AlOOH-900 catalysts were synthesized by the impregnation method. The 10%Ag/nano-Al2O3 catalyst showed 89% ozone conversion for 40 ppm O3 for 6 h under a space velocity of 840 000 h–1 and a relative humidity of 65%, which is superior to 10%Ag/AlOOH-900 (45% conversion). The characterization results showed Ag nanoparticles to be the active sites for ozone decomposition, which were more highly dispersed on nano-Al2O3 as a result of the greater density of terminal hydroxyl groups. The understanding of the dispersion and valence of silver species gained in this study will be beneficial to the design of more efficient supported silver catalysts for ozone decomposition in the future.
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DOI
高影响因子
IEEE TRANSACTIONS ON ELECTRON DEVICES
·
2023
·Vol. 70
·期 8
·4251-4256
·
IF 3.1
Biao He,Yongkai Jing,Xinfa Zhu,Chao Fan,Chun Sun,Yonghui Zhang,Mengjun Wang,Hongxing Zheng,Erping Li
In this work, light detectors utilizing p-type tin monosulfide (p-SnS) few layers with an Au/SnS/Ag Schottky structure are demonstrated. These detectors exhibit broad-spectrum light detection capabilities spanning the visible to near-infrared (NIR) wavelength range. Notably, under NIR 850 nm illumination, the detectors exhibit exceptional photodetection performance with an ultrahigh responsivity of up to 1652.87 $\text{A}\cdot \text{W}^{-{1}}$ , an extremely specific detectivity of $8.05\times 10^{{12}}$ cm $\cdot $ Hz $^{\text {1/{2}}}\cdot \text{W}^{-{1}}$ , and a rapid response time of approximately 6.5 ms. These characteristics surpass those of most 2-D materials-based detectors and even outperform commercial InGaAs (Hamamatsu, InGaAs G8370-85) and Silicon (Hamamatsu, Si S9119-01) detectors. The remarkable photoresponse is attributed to the SnS/Ag Schottky structure, which facilitates the separation of excited electron–hole pairs. Our findings suggest a promising route for developing high-performance optoelectronics based on p-SnS.
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DOI
高影响因子
Nanocomposites
·
2019
·
IF 0
Lian Xiong,Shaodi Zheng,Zewang Xu,Zhengying Liu,Wei Yang,Mingbo Yang
In the present work, micropores and a low filler content of Ag@SiO2 nanoparticles (NPs) are synchronously introduced into polydimethylsiloxane (PDMS) film to obtain porous dielectric elastomeric composites. The morphology and dielectric and mechanical properties of the composites are investigated. The resulting composites possess high dielectric permittivity, low dielectric loss and low Young’s modulus, which is beneficial to the requirements of a dielectric elastomer actuator. This study provides an effective method to prepare high-performance PDMS-based dielectric porous dielectric elastomeric composites filled with low filler contents of Ag@SiO2 NPs.
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DOI
Desalination and Water Treatment
·
2024
·
IF 1
Guangcheng Luo,Zhigang Jia,Tao Ni,Ziyu Li,Jun Chen,Hongping Wu,Nannan Wang
In this study, the novel three-dimensional porous silver/polydopamine/polyurethane (Ag/PDA/PU) sponge was synthesized by a facile method. The PU sponge modified by polydopamine (PDA/PU) was employed not only as a carrier but also as a reducing agent. Ag ions can be in situ reduced on the fiber surface of PDA/PU sponge. The as-prepared Ag/PDA/PU sponge was characterized by X-ray powder diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscope (SEM), and energy-dispersive X-ray (EDX). The results showed that the as-formed Ag nanoparticles had been successfully loaded onto the fiber surface of the sponge. The Ag/PAD/PU sponge exhibited higher catalytic activity for the organic pollutant in wastewater with the assistance of NaBH 4 medium. The novel Ag/PDA/PU sponge has the potential application for the treatment of wastewater containing organic pollutant due to its high catalytic efficiency, low cost, and facile synthesis process.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2022
·
IF 9.221
Jialin Chen,Yonghong Lu,Lanjun Liu,Haibo Xu
Maintenance-free, cost-effective, and long-lasting potentiometric sensors are highly anticipated for marine detection. Solid-state silver/silver chloride (Ag/AgCl) is considered the most suitable non-polarizable electrode for that purpose. However, the conventional fabrication of thin-film or porous Ag/AgCl electrodes has limitations in the case of simultaneous cost-effectiveness and stability endurance. In the present study, the multi-walled carbon nanotube (MCNT)/Ag/AgCl composite electrode with a 70 mg/cm 2 Ag load was prepared, having nanoporous MCNT/Ag conductive skeleton, and a three-dimensionally spreading Ag/AgCl thin layer. The prepared MCNT/Ag/AgCl composite electrode showed an excellent electrode performance, including low resistance, high exchange current density , and stable potential with long-term stability and low cost. The process kinetics and self-repairing mechanism between Ag and AgCl with the help of MCNT were elucidated. The usage of MCNT/Ag/AgCl composite electrode as a solid-state reference electrode and ocean electric field sensor was successfully evaluated, which provides a promising marine potentiometric sensor application for this nanoporous metal composite electrode via a novel preparation method.
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高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yanan Yan,Youhong Tang,Dan Chang,Shengmei Song,Ayesha Aziz,Muhammad Asif,Shaomin Shuang,Chuan Dong
Multi-color carbon dots (CDs), as advanced carbon nanomaterials with exceptional features, have gained significant attention, yet the facile and rapid synthesis of CDs with tunable multi-color emission from a single carbon source remains a challenge. By simply varying the solvent (water, EtOH, or DMF), blue-, green-, and yellow-emitting CDs are obtained, with corresponding tunable emission peaks of 469, 485, and 528 nm and quantum yields of 31.2 %, 34.1 % and 35.0 %. This emission tunability attributed to variations in their carbon core and surface states. Furthermore, multi-color CDs are employed as fluorescent probes to assess their detection capabilities. The multi-color CDs enabled highly sensitive Ag + detection, achieving detection limits of 4 pM, 34 pM, and 42 pM, respectively. This strategy enabled a multichannel smartphone platform for on-site analysis, with the CDs also proving effective for bioimaging in HeLa cells and zebrafish, collectively establishing their dual potential for environmental and biomedical applications.
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2017
·Vol. 41
·期 22
·13327-13335
·
IF 3.269
Ce Gao,Qing-Da An,Zuoyi Xiao,Shangru Zhai,Bin Zhai,Zhan Shi
Nanosilver/alginate composite beads were successfully fabricated via a simple one-pot encapsulation method and were effectively applied to degradation experiments with p-nitrophenol under batch and fixed-bed conditions. Three-dimensional alginate hydrogels cross-linked with calcium ions were used as supporting matrix for “confinement” of the nanosilver, leading to the formation of nanosilver/alginate composite beads without significant aggregation of active nanoparticles. The samples were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and X-ray photoelectron spectroscopy. As-fabricated bead-like samples showed excellent catalytic efficiency at ambient temperature; material with 10% silver content required 170 seconds to catalyze hydrogenation of highly toxic p-nitrophenol under batch conditions. Good stability was also demonstrated in the process of dynamic catalytic degradation, which showed continuous high conversion performance for 4-NP; about 40 minutes at 298 K and residual concentration reached 0.0335 mg L−1 at a flow rate of 1 mL min−1. A pseudo-first order kinetic model described the relationship between concentration and time well; the rate constant k is 0.0149 s−1. Very favorably, the way to recycle the catalyst is very simple, namely filtration only is enough. In addition, the catalytic capability did not decline significantly after 10 recycles and average conversion content was still 97.96%.
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高影响因子
Foods
·
2026
·Vol. 15
·期 3
·479
·
IF 5.1
Baizhi Cen,Juge Liu,Mengyuan Tan,Bo Wang,Lu Gao,Zhenquan Yang,Genxi Zhang,Tao Zhang,Xuechao Xu
In this study, a silver-based metal–organic framework (Ag-MOF) nanozyme was synthesized for the synergistic eradication of drug-resistantSalmonellaenteritidisin food matrices. Ag-MOF exhibits multiple enzyme-like activities, namely oxidase (OXD)-, peroxidase (POD)-, and superoxide dismutase (SOD)-like activities. It demonstrated excellent antibacterial and antibiofilm activities against erythromycin- and chloramphenicol-resistantS. enteritidisstrains (N29 and P23). Specifically, treatment with 20 mg mL−1Ag-MOF resulted in nearly complete eradication ofS. enteritidisin in vitro suspension assays, including 1 × 107CFU mL−1N29 strain and 6 × 106CFU mL−1P23 strain. Moreover, treatment with 1 mg mL−1Ag-MOF led to 80~90% biofilm inhibition ofS. enteritidis. Mechanistic investigations revealed that Ag-MOF effectively interacted with amino-rich structures on the bacterial surface (such as membrane proteins and peptidoglycan components), generated abundant reactive oxygen species (ROS), released Ag+ions, and depleted intracellular glutathione, which collectively disrupted cell membrane integrity and induced severe leakage of intracellular proteins and nucleic acids. Importantly, Ag-MOF maintained high antibacterial efficacy in complex simulated food matrices (pork, milk, and egg shell). Overall, this study offers key insights into enzyme-mimicking antibacterial materials and a promising strategy to combat multidrug resistant foodborne pathogens.
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DOI
PubMed
高影响因子
RSC Advances
·
2014
·Vol. 5
·期 8
·5604-5610
·
IF 3.708
Mei Yu,Jindan Zhang,Songmei Li,Yanbing Meng,Jianhua Liu
The performances of photovoltaic devices can be improved by increasing light-harvesting and charge collection respectively. The design and synthesis of nanocomposites with the ability of enhancing the generation and collection of the photo-generated electrons provide a significant way to improve the power conversion efficiency (PCE). Herein, SWNTs@(TiO2/Ag/Au) nanocomposites were synthesized and successfully integrated into photoanode films of dye-sensitized solar cells (DSSCs) to improve the power conversion efficiency. The synthesis processes were based on multi-functional DNA. DNA not only works as a dispersing agent preventing SWNTs bundling but also as a sacrificial mold assembling TiO2, Ag and Au nanoparticles on the surface of the SWNTs. The synthesized SWNTs@(TiO2/Ag/Au) nanocomposites enhance the charge collection and light-harvesting of DSSCs simultaneously. With 2.45 wt% SWNTs@(TiO2/Ag/Au) nanocomposites incorporating into the photoanode films, the PCE of the DSSCs increases from 6.8% to 8.3%.
研究领域:
材料科学
·
纳米科技
·
能源化学
·
光伏器件
·
表面科学
·
胶体与界面化学
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高影响因子
危险品化学品经营许可证（带存储）