ENVIRONMENTAL RESEARCH
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2023
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IF 8.3
Jinbin Lai,Ting Tang,Xiaodong Du,Rui Wang,Jiahao Liang,Dehao Song,Zhi Dang,Guining Lu
As emerging pollutants continue to be discovered, studies on the degradation behavior of emerging pollutants have proliferated, but few studies have focused on the reactivity of the new pollutants themselves. The work investigated the oxidation of a representative roadway runoff-derived organic contaminant , 1,3-diphenylguanidine (DPG) by goethite activated persulfate (PS). DPG exhibited the highest degradation rate ( k d = 0.42 h −1 ) with present of PS and goethite at pH 5.0, then started to decrease with increasing pH. Chloride ion inhibited DPG degradation by scavenging HO·. Both HO· and SO 4 − · were generated in goethite activated PS system. Competitive kinetic experiments and flash photolysis experiments were conducted to investigate free radical reaction rate. The second-order reaction rate constants for DPG reacting with HO· and SO 4 − · were quantified ( k DPG + HO·, k DPG + SO4 - · ), which both reached above 10 9 M −1 s −1 . Chemical structures of five products were identified, four of them were previously detected in DPG photodegradation , bromination and chlorination processes. By density functional theory (DFT) calculations, ortho- and para- C were more easily attacked by both HO· and SO 4 − ·. ion of H on N by HO· and SO 4 − · were the favorable pathways, and the product TP-210 might be generated by cyclization of DPG radical from abstraction of H on N (3). The results of this study help us to better understand the reactivity of DPG with SO 4 − · and HO·.
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FITOTERAPIA
·
2023
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IF 3.4
Dan Huang,Fanghua Li,Anquan Yang,Jing Wang,Min Xie,Meiling Mao,Jing Li,Xiaoli Zhang,Qingli Qu,Ranhua Xiong,Chaobo Huang
The study on the extraction conditions, purification, and biological activity of slash pine ( Pinus elliottii. ) is important for the development of slash pine resources. The optimal process conditions for the extraction of slash pine polysaccharide (SPP) were determined, resulting in a liquid-solid ratio of 66.94 mL/g, extraction temperature of 83.74 °C and extraction time of 2.56 h by using the response surface methodology, and the yield of SPP was 5.99% under the optimized conditions. Following the purification of SPP, the SPP-2 component was obtained and its physicochemical properties, functional group composition, antioxidant capacity, and moisturizing capacity were determined. Structural analysis suggested that SPP-2 has a molecular weight of 118.407 kDa, and was composed of rhamnose, arabinose, fucose, xylose, mannose, glucose, and galactose in a ratio of 5.98: 14.34: 1: 1.75: 13.50: 3.43: 15.79. The antioxidant activity analysis showed that SPP-2 has good free radical scavenging activity, and it was also found to have in vitro moisturizing activity and low irritation. These results suggest that SPP-2 has the potential for applications in the pharmaceutical, food, and cosmetic industries.
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DIAMOND AND RELATED MATERIALS
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2023
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IF 4.1
Yuan Xue,JinXia Wang,Hong Yuan,Hui Li
With the aim of preparing a sulfonic acid-type solid acid catalyst having a high density of acid sites and excellent stability, this work synthesized sulfonic acid bowl-shaped hydrothermal carbon microspheres (SA-OBHCs), using amine groups as the primary sulfonic acid bonding sites. This material was synthesized via a three-step functionalization process comprising the oxidation , amidation and sulfonation of BHCs. The extent to which chlorosulfonic acid reacted with amine groups in diethylenetriamine molecules on microsphere surfaces was also investigated using density functional theory calculations. These calculations showed that the substitution reaction of primary amines proceeded less readily than that of secondary amines but provided a more stable product. The surface acid d ensity of the SA-OBHCs was as high as 11.2 mmol·g −1 and the –SO 3 H groups on the SA-OBHCs were found to be thermally stable up to 200 °C. These SA-OBHCs were subsequently used to catalyze the synthesis of fatty acid methyl esters (FAMEs) from a waste frying oil model compound and methanol. Reactions performed using a methanol/oil molar ratio of 20:1 at 140 °C for 3 h gave a FAMEs yield of 93.4 %. After four reuses, an SA-OBHCs specimen provided a FAMEs yield of 77.5 %, demonstrating the significant stability of this material.
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Analytical Methods
·
2023
·Vol. 15
·期 26
·3251-3258
·
IF 3.1
Feifei Li,Congcong Hu,Wenen Su,Hao Liang,Fubing Xiao,Jinquan Liu,Yan Tan,Shengyuan Yang
L-Cysteine, widely used in medicine and the food industry, is of great essentiality to organisms and the food quality. Given that current detection approaches require exacting lab conditions and tedious sample treatment, there is a pressing demand for developing a method that possesses advantages of user friendliness, prominent performance, and cost-effectiveness. Herein, a self-cascade system was developed for the fluorescence detection of L-cysteine based on the ingenious performance of Ag nanoparticle/single-walled carbon nanotube nanocomposites (AgNP/SWCNTs) and DNA-templated Ag nanoclusters (DNA-AgNCs). The fluorescence of DNA-AgNCs could be quenched on account of the adsorption of DNA-AgNCs on AgNP/SWCNTs by π–π stacking. With the cooperation of Fe2+, AgNP/SWCNTs with oxidase and peroxidase-like activities could catalyze the oxidation of L-cysteine to produce cystine and hydrogen peroxide (H2O2) and then break the O–O bond of H2O2 to generate a hydroxyl radical (·OH), which could cleave the DNA strand into different sequence fragments which subsequently peeled off from the AgNP/SWCNTs, resulting in a “turn-on” fluorescence response. In this paper, AgNP/SWCNTs with multi-enzyme activities was synthesized enabling the reaction to proceed in just one step. The successful preliminary applications for the L-cysteine detection in pharmaceutical, juice beverage, and serum samples indicated that the developed method exhibited great potential in medical diagnosis, food monitoring, and the biochemical field, which also broadened the horizon for follow-up research.
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CHEMICAL ENGINEERING JOURNAL
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2023
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IF 15.1
Ying Zhang,Yunhai Chen,Dianwei Zhang,Huilin Liu,Baoguo Sun
Within this study, a peptide nanodots-bridged metal–organic framework (PNMOF) has been constructed by predictably assembling highly efficient fluorescent dipeptide nanodots into the three-dimensional framework upon coordination of Zn(II) and dihydroxamate linkers. The established system was on behalf of a new class of tripartite hybrid material, i.e., metal ion, organic linker, and peptide nanodot, which integrated the chemical and structural versatility in a modular fashion. Owing to its unique open framework with tripartite construction, PNMOF exhibited a rapid and sensitive response, therefore, the target (e.g., lambda-cyhalothrin, LCY) driven into the tripartite hybrid structure stimulated a cascade amplification effect. LCY can cause significant fluorescence quenching in the PNMOF-based cascade amplification platform due to the charge transfer mechanism, which was confirmed by density functional theory calculations. PNMOF-based cascade amplification platform was employed for fluorescence imaging detection of pyrethroids in solution and solid state assisted by the smartphone. The limit of detection was as low as 0.34 μg/L and the recoveries percentage in real agricultural products was calculated as 88.26–108.17%. This work not only underlies the structural diversity of conventional metal–organic framework but also offers a useful tool in environmental protection and food safety.
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MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 6
·1-12
·
IF 5.7
Niu Xiaohui,Zhao Rui,Yan Simeng,Li Hongxia,Yang Jing,Cao Kunjie,Liu Xiaoyu,Wang Kunjie
Abstract Chiral materials have drawn the widespread attention for their its chiral recognition ability. The design and synthesis of chiral material are of importance owing to the unpredictability in controlling chirality during the synthesis process. To circumvent problems, a chiral MOF (D-His-ZIF-8) was synthesized by ligand exchange of 2-methylimidazole (Hmim) on ZIF-8 by D-histidine (D-His), which can be treated as chiral host to distinguish amino acid enantiomers. The obtained D-His-ZIF-8 can provide chiral nanochannels for amino acid guests. Meanwhile, polynary transition-metal ion (Co 2+ and Fe 3+ ) coordinating with polydopamine (PDA) wrapped on the surface of D-His-ZIF-8 can increase the active sites. The electrochemical chiral recognition behavior showed that D-His-ZIF-8@CoFe-PDA exhibited good recognition of the tryptophan enantiomer (L/D-Trp) (working potential of −0.2 V vs. Hg/HgCl 2 ). The LOD and LOQ of L-Trp were 0.066 mM and 0.22 mM, respectively, while the LOD and LOQ of D-Trp were 0.15 mM and 0.50 mM, respectively. Finally, the usefulness of D-His-ZIF-8@CoFe-PDA/GCE was evaluated with a recovery of 94.4–103%. The analysis of real samples shows that D-His-ZIF-8@CoFe-PDA/GCE is a feasible sensing platform for the detection of L-Trp and D-Trp. Graphical abstract
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INDUSTRIAL CROPS AND PRODUCTS
·
2023
·
IF 5.9
Qingwen Zhu,Yujing Yang,Zheling Zeng,Ting Peng,Xianghui Yan,Junxin Zhao,Jiaheng Xia,Ping Yu,Xuefang Wen,Deming Gong
The study aimed to investigate the effects of processing methods on oil yield, chemical composition, physicochemical properties, antioxidant activity and volatile compounds of Cinnamomum camphora seed kernel oil (CCSKO). The processing methods used were hot pressing (HP), cold pressing (CP), solvent extraction (SE), aqueous extraction (AE), sub-critical fluid extraction (SCFE) and supercritical fluid extraction (SFE). The results showed that the extraction efficiencies from different processing methods ranged from 44.48% to 97.93%, with the highest efficiency from SCFE. All CCSKO samples were found to be rich in medium-chain saturated fatty acids (> 96%), and capric acid-capric acid-lauric acid accounting for the largest proportion of triacylglycerols (77.54%−78.74%). However, the total polyphenol content, δ-tocopherol content and antioxidant activity of AE, α-tocopherol and γ-tocopherol content of CP, and squalene content of SCFE were all significantly higher than those of the other samples. Additionally, the thermal behaviors and spectral profiles of all samples were similar. Furthermore, there were significant differences in the volatile compounds of CCSKO with different processing methods ( p < 0.05). Linalool , 2-nonanol, and ethyl caprate were determined to be the key aroma compounds of CCSKO. Overall, the results provide a theoretical reference for further processing of CCSKO.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Jinxin Li,Dan Zhong,Feiyu Li,Kefei Li,Wencheng Ma,Jun Ma,Jingna Zhang,Aoshuang Sun
A bifunctional electro-Fenton (EF) cathode with Fe 3 O 4 -LaFeO 3 /C embedded graphite felt (GF) was synthesized through a hydrothermal process, which was used for in situ electrochemical formation of active oxygen species (ROS) for coal pyrolysis wastewater (CPW) removal. Experimental results illustrated that the mineralization efficiency of dimethylphenol (DMP) was achieved at 90.7 % within 150 min reaction. On the basis of quenching test and free radical detection, the ∙OH and ∙O 2 − were the detectable ROS in the hetero-EF system for DMP removal. Meanwhile, the formed oxygen vacancies (OVs) and the redox of Fe 2+ /Fe 3+ promoted the oxygen adsorption and H 2 O 2 activation. Density functional theory (DFT) calculations further discussed that the Fe 3 O 4 -LaFeO 3 interface possessed more downward spin density of states in the conduction band, resulting in a higher total density of states (DOS) value near the Fermi level. Moreover, the Fe 3 O 4 -LaFeO 3 /C/GF cathode displayed good recyclability with low metal ion dissolution for 5 times (99.5 % DMP removal and 78.6 % TOC removal) and underlying actual CPW application potential (80.2 % of COD removal and 100 % of total phenol (Tph) removal). Overall, this work invented a novel and stable bifunctional cathode for the efficient removal of refractory CPW in the hetero-EF system.
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CATALYSIS COMMUNICATIONS
·
2023
·
IF 3.7
Dan Luo,Qin Wang,Jiansu Ran,Ruixue Yangcheng,Yuntong Cui,Shuang Luo,Jianjian Wang
A series of Zr-based catalysts were prepared using various commercial and cheap organic acids as the coordination agents, and these as-synthesized samples exhibited superior activities to produce lactic acid (LaA) from carbohydrates. Using humic acid (HA) as a typical coordination agent, LaA yield was up to 76% over the resultant Zr-HA, outperforming the most recent reported works. Deeper studies revealed that Zr-HA possessed both acid sites and base sites, and these dual active sites can simultaneously activate xylose, resulting in high yield production of LaA. Besides, Zr-HA also showed excellent reusability and can be reused at least five times.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2023
·Vol. 21
·期 1
·1-14
·
IF 10.2
Ma Bing,Ma Yingying,Deng Bo,Xiao Pengjun,Huang Pengyu,Wang Dali,Liu Lanxia
Certain chemotherapeutics can induce tumor cells’ immunogenic cell death (ICD), release tumor antigens, and thereby trigger personalized antitumor immune responses. Co-delivery of adjuvants using nanocarriers could amplify the ICD-induced tumor-specific immunity achieving a synergistic chemo-immunotherapeutic effect. However, complicated preparation, low drug loading efficiency, and potential carrier-associated toxicity are the major challenges that limited its clinical applications. Herein, a carrier-free core–shell nanoparticle (MPLA-CpG-sMMP9-DOX, MCMD NPs) was constructed by facile self-assembly of spherical nucleic acids (SNA) with two adjuvants of CpG ODN and monophosphoryl lipid A (MPLA) as a core and doxorubicin (DOX) radially around the dual-adjuvants SNA as a shell. The results demonstrated that MCMD NPs could enhance drugs accumulation in tumors, and release DOX upon enzymatic degradation of matrix metalloproteinase-9 (MMP-9) peptide in the tumor microenvironment (TME), which enhanced the direct-killing effect of DOX on tumor cells. The core of MPLA-CpG SNA efficiently boosted the ICD-induced antitumor immune response to further attack tumor cells. Thus, MCMD NPs achieved a synergistic therapeutic effect of chemo-immunotherapy with reduced off-target toxicity. This study provided an efficient strategy for the development of a carrier-free nano-delivery system for enhanced cancer chemo-immunotherapy.
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DYES AND PIGMENTS
·
2023
·
IF 4.5
Changxing Wang,Xiameng Li,Tingting Li,Yiru Wang,Guoqiang Guo,Siyuan Tang,Chenjie Gu,Da Chen
Multiple emission GQDs have always been the focus of researchers due to the unique emission characteristics and high-level application capabilities. Nevertheless, the most of GQDs with double emissions are formed by different chemical reactions, and the realization of double emission by adjusting the solvent environment is rarely reported. Here, the multi-doped and double-peak emissive GQDs (MD-GQDs) have been synthesized via one pot hydrothermal synthesis and re-dispersed in solvents with different polarity. Systematic characterizations of optical property indicate that the solvent polarity related double-peak emission photoluminescence is ascribed to the existence of multi-emissive centers in MD-GQDs from aromatic C O bond and surface/edge state (C–N/C–F). Furthermore, the double emission fluorescent mechanism of MD-GQDs has been proposed due to the electrostatic interaction between MD-GQDs and solvent molecules , which induces intramolecular charge transfer (ICT) effect in MD-GQDs. Finally, based on the unique solvent-induced discoloration behavior of MD-GQDs, a multi-mode anti-counterfeiting application based on organic solution as the secret key with easy operation and high visual effect is developed.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Qingyun Liu,Li Yang,Liangliang Wang,Zimu Li,Yongkang Yu,Yi Zheng,Daizheng Lian,Xianming Li,Hongzhong Chen,Lin Mei,Xiaowei Zeng,Nansha Gao
To resolve poor accumulation caused by systemic administration, injectable and responsive hydrogels are the prospective drug delivery systems for localized tumor treatment, owning to negligible invasiveness and accurate administration. Herein, an injectable hydrogel, based on dopamine (DA) crosslinked hyaluronic acid and Bi 2 Se 3 nanosheets (NSs) loading with doxorubicin (DOX) coated with polydopamine (Bi 2 Se 3 -DOX@PDA), was developed for synergistic chem-photothermal cancer therapy. The ultrathin functional Bi 2 Se 3 -DOX@PDA NSs could be responsive to the weak acidic condition and photothermal effect under NIR laser irradiation, achieving controlled release of DOX. Moreover, nanocomposite hydrogel based on hyaluronic acid matrix could be precisely administrated through intratumoral injection since its injectability and self-healing capacity, remaining at injected sites for at least 12 days. Furthermore, the excellent therapeutics effect of Bi 2 Se 3 -DOX@PDA nanocomposite hydrogel was demonstrated on 4 T1 xenograft tumor with outstanding injectability and negligible systemic side-effect. In short, the construction of Bi 2 Se 3 -DOX@PDA nanocomposite hydrogel paves a prospective path for local treatment of cancers.
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