MICROCHIMICA ACTA
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2022
·Vol. 189
·期 11
·1-8
·
IF 6.408
Li Shuhuai,Wu Yuwei,Pang Chaohai,Ma Xionghui,Wang Mingyue,Luo Jinhui,Zhi Xu,Li Bei
A highly sensitive kanamycin electrochemiluminescence (ECL) switch sensor was constructed. A signal element consisting of ordered mesoporous carbon loaded with indium oxide nanoparticles/carbon quantum dots (OMC/In 2 O 3 /C-dots) was assembled on the surface of a gold electrode. Then, a molecularly imprinted polymer (MIP) was prepared on the modified electrode surface using kanamycin as the template molecule and o -aminophenol as the functional monomer. After kanamycin elution, the prepared sensor retained specific kanamycin recognition sites. OMC/In 2 O 3 effectively amplified the ECL signal of the C-dots, thereby enhancing the detection sensitivity, whereas kanamycin quenched the signal. Therefore, the imprinted sites acted as a switch, providing a new method for detecting kanamycin. Under the optimal experimental conditions, the concentration of kanamycin was proportional to the degree of ECL quenching within a linear range of 5–4500 × 10 −12 mol L −1 at 0.8 V (vs. Ag/AgCl electrode electrode), and the detection limit was 5.8 × 10 −13 mol L −1 . When applied to the detection of kanamycin in actual samples, such as chicken, duck, pork, and milk, the recovery for spiked samples was in the range 92.7–110%. Graphical abstract
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JOURNAL OF ELECTRONIC MATERIALS
·
2022
·Vol. 51
·期 12
·6964-6974
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IF 2.047
Geng Zhibin,Liu Hong,Xiong Wei
Polymer/conductor composites are used in energy storage capacitors; however, they exhibit high interface leakage currents, causing low breakdown strength. Here, a ternary-blend strategy was used to synthesize polyvinyl chloride (PVC)/titanium carbide transition-metal carbide two-dimensional nanolayered material (Ti 2 C MXene)/diamond composites using solution casting. The PVC matrix exhibited low polarity and high insulation, while the Ti 2 C MXene and diamond fillers exhibited high conductivities and ultrahigh insulation properties, respectively. Overall, the PVC/Ti 2 C/diamond ternary composites exhibited better electrical properties than the PVC/Ti 2 C binary composites. In the ternary composites, PVC/Ti 2 C interface polarization caused high dielectric constants, while low leakage currents induced by diamond caused low dielectric losses and high breakdown strength. The optimum-composition (12 wt.% Ti 2 C and 4 wt.% diamond) ternary composite exhibited a high dielectric constant (~153 at 100 Hz), low dielectric loss (~0.14 at 100 Hz), low conductivity (~1.4 × 10 −6 S m −1 at 100 Hz), and high breakdown strength (~312 MV m −1 under a direct current field). This study indicates a synergistic effect between Ti 2 C MXene and diamond in the composite dielectrics, and could guide the fabrication of dielectric films for capacitors. Graphical Abstract
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JOURNAL OF FLUORESCENCE
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2022
·Vol. 32
·期 6
·2343-2350
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IF 2.525
Liu Tao,Zhang Shuai,Fan Xiaoyu,Yang Dou,Wang Min,Shao Xiaodong,Wang Shuhao,Yue Qiaoli
Carbon dots (CDs) were used to develop a sensitive sensing technique for detecting Cr(VI). CDs were made using a hydrothermal technique from citric acid and glutamic acid. These prepared CDs emitted blue fluorescence under excitation of 350 nm (λ em = 420 nm), and the fluorescence quantum yield was 48.41%. Transmission electron microscope was used to examine the morphology of the CDs, which had an average size of 2.21 ± 0.39 nm. The elementary composition and bonding structure of the CDs were conducted by XPS and FT-IR spectrum. Cr(VI) quenched the fluorescence of CDs through a static quenching effect and an inner filter effect, allowing Cr(VI) to be detected quantitatively. This approach was used to detect Cr(VI) in two samples of water, with the findings demonstrating that it is reliable and accurate. The fluorescence intensity change was linearly related to the concentration of Cr(VI) in the range from 0.5 to 400 μM, with the detection limit being 0.10 μM. This approach has the virtues of wide detection range, low cost and fast response. The strategy has a great application prospect for detecting Cr(VI) in practical samples.
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Advanced Composites and Hybrid Materials
·
2022
·Vol. 5
·期 4
·3023-3034
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IF 11.806
Xu Yaoyuan,Zhang Runze,Zhong Zhengxiang,Yang Ling
Sunlight is one of the most significant energy sources that we utilized in our daily life. Although it brings great benefits to us, due to the high energy of the ultraviolet part in sunlight, long time exposure to sunlight may cause severe problems to both humans and materials, such as skin cancer, material fatigue, and degradation. Also, the infrared part of the light can also lead to energy accumulation, heating the surface in an undesirable way. In order to ameliorate the ultraviolet shielding ability of thermochromic materials. In this paper, we synthesized a kind of novel film materials through coordinated self-assembly at room temperature in a very simple and green method. The material is mainly composed of two kinds of metal salts (Cr(NO 3 ) 3 ·9H 2 O and CuSO 4 ·5H 2 O) and octa-aminopropyl POSS, exhibiting great reversible thermochromic property from 20 to 80 ℃, superb UV shielding (100%) performance, and excellent infrared shielding (99%) ability. By increasing the ratio of CuSO 4 ·5H 2 O, the UV shielding effectiveness was enhanced and it achieved nearly 100% along with 99% IR shielding effectiveness at 780–1400 nm when the addition is 50%. The relevant mechanisms were illustrated by decomposition analysis through UV–Vis spectroscopy, in situ XPS, in situ XRD, FT-IR, TG-MS tests, and molecular simulations. These unique properties make this material very promising in various areas, such as new generation smart windows, functional coatings, and temperature sensors. Graphical abstract
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Nature Communications
·
2022
·Vol. 13
·期 1
·1-13
·
IF 17.694
Ge Xiaohu,Dou Mingying,Cao Yueqiang,Liu Xi,Yuwen Qiang,Zhang Jing,Qian Gang,Gong Xueqing,Zhou Xinggui,Chen Liwei,Yuan Weikang,Duan Xuezhi
Mechanism driven catalyst design with atomically uniform ensemble sites is an important yet challenging issue in heterogeneous catalysis associated with breaking the activity-selectivity trade-off. Herein, a trimer Ni 1 Sb 2 site in NiSb intermetallic featuring superior selectivity is elaborated for acetylene semi-hydrogenation via a theoretical guidance with a precise synthesis strategy. The trimer Ni 1 Sb 2 site in NiSb intermetallic is predicted to endow acetylene reactant with an adequately but not excessively strong σ-adsorption mode while ethylene product with a weak π-adsorption one, where such compromise delivers higher ethylene formation rate. An in-situ trapping of molten Sb by Ni strategy is developed to realize the construction of Ni 1 Sb 2 site in the intermetallic P6 3 /mmc NiSb catalysts. Such catalyst exhibits ethylene selectivity up to 93.2% at 100% of acetylene conversion, significantly prevailing over the referred Ni catalyst. These insights shed new lights on rational catalyst design by taming active sites to energetically match targeted reaction pathway.
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Lipids in Health and Disease
·
2022
·Vol. 21
·期 1
·1-20
·
IF 4.315
Ge Jian,Xu Wei-jia,Chen Hai-feng,Dong Zong-hua,Liu Wei,Nian Fu-zhao,Liu Jun
Objective The purpose of this study was to explore the effect of cigarette smoke component (CSC) exposure on serum lipid levels in rats and the underlying molecular mechanism. Methods Male SPF-grade SD rats were randomly divided into a control group and a CSC exposure group, with the CSC group being exposed to CSC for 6 weeks. RT–PCR and Western blotting methods were used to detect lipid metabolism gene expression in rats, and 16S RNA gene sequencing was used to detect the gut microbiota in the rat cecum. Rat serum exosomes were prepared and identified, and the interaction of exosomal miR-291a-3p and miR-126a-5p with AMPK and CYP7A1 was detected by a dual luciferase reporter gene assay (DLRG). Results Serum indicators, including cholesterol levels and trimethylamine oxide (TMAO) content, were significantly affected in the CSC exposure group compared with the control group ( P < 0.05), and the expression levels of adenylate-activated protein kinase (AMPK), acetyl-coenzyme A carboxylase (ACC) and HMG-CoA reductase (HMG-CoAR) genes were significantly increased ( P < 0.05) in the liver, while the expression level of cholesterol 7α-hydroxylase (CYP7A1) was markedly decreased ( P < 0.01). 16S rRNA gene sequencing of the gut microbiota in the rat cecum showed that the abundance of Firmicutes in the CSC group increased significantly at the phylum level, while the abundances of Bacteroidota and Spirochaetota were reduced significantly ( P < 0.01). The relative abundance of Romboutsia, Turicibacter, and Clostridium sensu stricto increased significantly ( P < 0.01), and the relative abundance of Prevotella, Muribaculaceae_norank, Lachnospiraceae NK4A136 group, Roseburia, Treponema, and Ruminococcus significantly decreased ( P < 0.01) at the genus level. In addition, the exosome miR-291a-3p and miR-126a-5p levels were markedly regulated by CSC exposure ( P < 0.01). The interactions of miR-291a-3p and miR-126a-5p with AMPK and CYP7A1 mRNA were also validated by the DLRG method. Conclusions In summary, the rat dyslipidemia induced by CSC exposure may be related to the interference of gut microbiota structure and interaction of miRNAs from serum exosomes with target mRNAs, which further regulated AMPK-ACC/CYP7A1 signaling in rats.
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JOURNAL OF POLYMERS AND THE ENVIRONMENT
·
2022
·Vol. 31
·期 2
·565-578
·
IF 4.705
Yu Huijie,Yan Qi,Yang Zhijun,Mei Jun,Xie Jing
This research was to evaluate the effects of locust bean gum (LBG) and carboxymethyl chitosan (CMCS) active coatings supplemented with Melissa officinalis L. essential oil (MOEO) nanoemulsions to extend the shelf life of sea bass ( Lateolabrax japonicus ) fillets during refrigerated storage at 4 °C. The results indicated that the active coatings could delay the increase in microbiological, pH, and K value of sea bass fillets. At the same time, the active coatings markedly depressed the off-flavor compounds productions such as the trimethylamine (TMA), total volatile basic nitrogen (TVB-N), hypoxanthine (Hx), hypoxanthine riboside (HxR) and reduced free amino acids (FAAs) accumulation during refrigerated storage. 24 volatile compounds were identified and the active coatings treated significantly reduced the fishy flavor compounds, such as 2-ethyl-1-hexanol, 3-methylbutanol, 2-methylbutanol, hexanal, and 1-octen-3-one. The shelf life of uncoated sea bass was 6 days, and sea bass treated with CMCS/LBG, CMCS/LBG-0.5%MOEO, CMCS/LBG-1%MOEO and CMCS/LBG-2%MOEO were 6, 9, 12 and 15 days, respectively, which suggested that the active coatings were a potential option in maintaining the quality of sea bass during refrigerated storage. Graphical Abstract
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Nature Communications
·
2022
·Vol. 13
·期 1
·1-9
·
IF 17.694
Shi Benbing,Pang Xiao,Li Shunning,Wu Hong,Shen Jianliang,Wang Xiaoyao,Fan Chunyang,Cao Li,Zhu Tianhao,Qiu Ming,Yin Zhuoyu,Kong Yan,Liu Yiqin,Zhang Mingzheng,Liu Yawei,Pan Feng,Jiang Zhongyi
The idea of spatial confinement has gained widespread interest in myriad applications. Especially, the confined short hydrogen-bond (SHB) network could afford an attractive opportunity to enable proton transfer in a nearly barrierless manner, but its practical implementation has been challenging. Herein, we report a SHB network confined on the surface of ionic covalent organic framework (COF) membranes decorated by densely and uniformly distributed hydrophilic ligands. Combined experimental and theoretical evidences have pointed to the confinement of water molecules allocated to each ligand, achieving the local enrichment of hydronium ions and the concomitant formation of SHBs in water-hydronium domains. These overlapped water-hydronium domains create an interconnected SHB network, which yields an unprecedented ultrahigh proton conductivity of 1389 mS cm −1 at 90 °C, 100% relative humidity.
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MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 11
·1-15
·
IF 6.408
Qin Dongmiao,Meng Shuo,Wu Yusheng,Luo Zhi,Deng Biyang
An efficient electrochemiluminescence resonance energy transfer (ECL-RET) method is proposed which combines the luminescent materials of tris(4,4′-dicarboxylicacid-2,2′-bipyridyl) ruthenium(II) (energy donor) and tin dioxide and tin disulfide quantum dots (SnO 2 /SnS 2 QDs) (energy acceptor) into the isoreticular metal − organic framework-3 (IRMOF-3) material to form a composite. In this mode, the distance between the energy donor and the acceptor was greatly shortened, reducing the energy loss, and thereby effectively improving RET efficiency and further significantly improving the ECL signal. The obtained composite (SnO 2 /SnS 2 QDs-Ru@IRMOF-3) was combined with sandwich immunoreaction to construct an ECL immunosensor for the sensitive detection of procalcitonin (PCT). Under the optimized experimental conditions with a working potential of − 1.48 V (vs Ag/AgCl), the proposed PCT biosensor exhibited a linear concentration range of 1 × 10 −4 –200 ng mL −1 , with a detection limit of 0.029 pg mL −1 ( S / N = 3). The biosensor was used to detect PCT in actual samples. The biosensor has broad application prospects in biological analysis and clinical diagnosis due to its high sensitivity, good selectivity, and good stability. Graphical abstract
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Cell Communication and Signaling
·
2022
·Vol. 20
·期 1
·1-11
·
IF 7.525
Yang Jing,Tang Xujiao,Li Baiqiang,Shi Jinsong
In acute pancreatitis, activation of inflammatory signaling, including the nuclear factor-kappa B (NF-κB) pathway, within acinar cells is known to be an early intracellular event occurring in parallel with pathologic trypsinogen activation. Sphingosine 1-phosphate receptor 2 (S1PR2) plays a critical role in endothelial inflammation, and our previous studies reported that S1PR2 deficiency significantly reduced the inflammatory response in liver injury under cholestasis conditions. However, the role of S1PR2 in inflammatory signaling activation within acinar cells and inflammatory responses during acute pancreatitis has not been elucidated. Here we report that S1PR2 was upregulated in the whole pancreas during acute pancreatitis. Blockade of S1PR2 by pharmacologic inhibition of S1PR2 by JTE-013 or AAV-mediated knockdown of S1PR2 improved the severity of pancreatic injury, as indicated by a significant reduction in inflammation and acinar cells death in acute pancreatitis mice. Moreover, S1PR2 is the predominant S1PRs expressed in pancreatic acinar cells and mediates NF-κB activation and the early inflammatory response within acinar cells under acute pancreatitis conditions via ROCK signaling pathways, not extracellular signal-regulated kinase pathways or p38 mitogen-activated protein kinase pathways. In addition, S1PR2 mediated macrophage NF-κB activation, migration and polarization toward the M1 phenotype. Therefore, these results demonstrated that the S1PR2-mediated early inflammatory response in acinar cells promotes the progression of acute pancreatitis, successfully linking local events to the systematic inflammatory response and leading to a novel therapeutic target for acute pancreatitis aimed at halting the progression of the inflammatory response.
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CHEMICAL PAPERS
·
2022
·Vol. 76
·期 12
·7535-7544
·
IF 2.146
Hu Aiyun,Wang Haijun,Ding Jian
In this study, a functionalized, heterogeneous, and insoluble acid catalyst of yeast-sulfonic acid was prepared by simple steps using spent yeast and sulfonic acid as raw materials. Its unique internal microstructure and abundant sulfonic acid groups on the surface endow it with the properties of Brønsted acid and high-performance activity. The catalyst was characterized by Fourier transform infrared spectroscopy, powder X-ray diffraction, scanning electron microscopy, transmission electron microscopy, Barrett–Emmett–Teller N 2 adsorption–desorption analysis, X-ray photoelectron spectroscopy, and thermogravimetric analysis. The catalyzed synthesis of ethyl levulinate (EL) from furfuryl alcohol (FA) was carried out at a temperature of 120 °C for 2 h. The conversion rate and yield percentages for the catalyzed reaction of FA to produce EL were 98.2 and 94.7%, respectively. The results show that the amount of catalyst used and reaction conditions significantly impacted the EL yield and FA conversion rate. Overall, the possible reaction mechanism for the conversion of FA to EL was proposed. It was found that the main reason for the high catalytic activity of the catalyst was the effect of Brønsted acid sites.
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EUROPEAN FOOD RESEARCH AND TECHNOLOGY
·
2022
·Vol. 248
·期 11
·2857-2864
·
IF 3.498
Ouyang Xiaoyan,Fan Yunyan,Huang Shan,Liu Xiaoling
Nitrofurans, a kind of banned antibiotics for their serious toxic side effects, have often been found in aquatic products in the past and are still found nowadays which were a severe threat for human health. A rapid quantization of nitrofuran metabolites residues in aquatic products by ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method was developed in this study. The experimental operation consisted of an acid-catalyzed release of protein-bound metabolites, followed by derivatization with 2-chlorobenzaldehyde (2-CBA) and then extraction with ethyl acetate before analysis by positive electrospray ionisation (ESI + ) with multiple reaction monitoring (MRM) type. 2-CBA was employed as derivatization reagent in this study, which greatly reduced the derivatization time. The linearity range for the four analytes were 0.25–50 μg kg −1 with good determination coefficients ( R 2 > 0.9982). The limit of detection (LOD) were 0.1 μg kg −1 , 0.1 μg kg −1 , 0.3 μg kg −1 , 0.3 μg kg −1 and the limit of quantification (LOQ) were 0.3 μg kg −1 , 0.3 μg kg −1 , 0.9 μg kg −1 , 0.9 μg kg −1 for AOZ, AMOZ, SEM, and AHD, respectively. Recovery rates were ranged from 90% to 114% for fortified samples at levels of 1.0 μg kg −1 , 5.0 μg kg −1 and 10 μg kg −1 with relative standard deviation values ranging from 1.6% to 5.8%. The developed method was successfully applied in 100 aquatic products for NFs metabolites detection and the results were further confirmed by the national standard GB/T 21311-2007 method.
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