Journal of Energy Storage
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2024
·
IF 8.9
Xudong Xu,Shuai Yin,Xinyu Zhai,Zide Wu,Jinlong Wang,Jiangfeng Ma,Xiaotian Peng,Hao Peng
Nano-encapsulated phase change materials (NEPCMs) with appropriate phase change temperature range and excellent anti-permeability have significant application value in the field of thermal regulation dressings. In this study, NEPCMs were synthesized using the microemulsion polymerization method, with eutectic fatty acids (LA-SA) as the core material and poly(methyl methacrylate) (PMMA) as the shell material. Subsequently, using the electrostatic adsorption method, chitosan (CS) was successfully coated onto the outer surface of NEPCMs, resulting in the preparation of a novel bilayer shell nano-encapsulated phase change materials (BS-NEPCMs) for thermal regulation dressings. The impact of core/shell ratio, CS acid solution concentration and cross-linking agent content on capsule properties was investigated. It was found that BS-NEPCMs exhibited excellent cyclical stability and thermal stability. In particular, the CS shell layer provided excellent interfacial impermeability effects for the capsules, achieving an anti-permeability efficiency of 96.21 %. This not only helps address the problem of high leakage rates in single wall capsules, but also ensures that the capsules maintain high phase change enthalpies of 99.32 J/g and 96.38 J/g, respectively. The dressings based on BS-NEPCMs demonstrated good thermal regulation at 33–42 °C with maximum phase change enthalpies of 39.53 J/g and 34.08 J/g, respectively. Swelling and rheological analysis showed that the dressing exhibits a gel state, with a swelling ratio of 343 %, an elastic modulus of 15 kPa and a viscous modulus of 4 kPa. This study indicated that BS-NEPCMs hold significant promise for various applications in energy storage and body thermal regulation fields.
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FOOD HYDROCOLLOIDS
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2024
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IF 11
Haiyu Du,Xinru Liu,Xiaoli Sun,Heng An,Yiyi Li,Zhu Zhu,Yongqiang Wen
Microbial infections result in significant postharvest losses of fresh produce. Microbial metabolism and variation in the quality of fruit and vegetables caused by microbial infection are accompanied by significant carbon dioxide (CO 2 ) production, contributing to a decreased pH value of the headspace microenvironment. Hence, the work aimed to design a CO 2 -responsive label with freshness indication, stimuli-responsive release antimicrobials, and adhesion for postharvest preservation. The multifunctional label (Eug/CPDH) was prepared by incorporating a mixed methyl red/bromothymol blue dye as an indicator and eugenol (Eug) as an antimicrobial agent into a matrix constructed by crosslinking 3-carboxyphenylboronic acid-grafted chitosan and dopamine-grafted hyaluronic acid (CPDH) through acid-sensitive borate bonds. The microbial infection could be indicated to visualize the freshness. Meanwhile, the label showed a CO 2 -responsive release ability, as confirmed by the release experiment. The antimicrobial test showed that the label had excellent inhibition properties against Escherichia coli , Staphylococcus aureus , and Botrytis cinerea . More importantly, the label could be conveniently adhered to the inner surface of the packaging and its effectiveness was verified by strawberry preservation experiments. At room temperature, the strawberry's reduction in hardness, vitamin C , total phenolic content, anthocyanins , and antioxidant capacity was effectively suppressed, and the shelf life was extended to 5 days. Overall, the CO 2 -responsive label provided a new strategy for developing multifunctional freshness preservation materials.
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JOURNAL OF NANOPARTICLE RESEARCH
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2017
·Vol. 19
·期 10
·1-12
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IF 2.02
Tian Fei,Niu Libo,Chen Bo,Gao Xuejia,Lan Xingwang,Huo Li,Bai Guoyi
A novel magnetic core-shell nanocomposite Fe 3 O 4 @Chitosan@ZnO was successfully prepared by in situ chemical precipitation method. It has a clear core-shell structure with magnetic Fe 3 O 4 (about 160 nm in diameter) as core, chitosan as the inner shell, and ZnO as the outer shell, as demonstrated by the transmission electron microscopy and the related elemental mapping. Moreover, this nanocomposite has high magnetization (43.6 emu g −1 ) so that it can be easily separated from the reaction mixture within 4 s by an external magnetic field. The introduction of the natural chitosan shell, instead of the conventional SiO 2 shell, and its combination with the active ZnO ensures this novel nanocomposite green character and good catalytic performance in the synthesis of 2-benzimidazoles with moderate to excellent isolated yields at room temperature. Notably, it can be recycled seven times without appreciable loss of its initial catalytic activity, demonstrating its good stability and making it an attractive candidate for the green synthesis of 2-benzimidazoles.
A novel magnetic core-shell nanocomposite exhibited high activity and good stability in the green synthesis of 2-benzimidazoles under mild reaction conditions.
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Analytical Methods
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2017
·Vol. 9
·期 35
·5149-5155
·
IF 1.9
Zhenliang Li,Zunli Mo,Ruibin Guo,Shujuan Meng,Ruijuan Wang,Huhu Gao,Xiaohui Niu
A novel chiral electrochemical sensor based on hydroxyethyl chitosan (HECS) covalently binding with the carboxylic multi-walled carbon nanotubes (MWCNT–COOH) was fabricated for discrimination of tryptophan (Trp) enantiomers. HECS preferably combined with L-Trp than with D-Trp because of the favorability of host–guest interactions between HECS and Trp enantiomers. Thus, the recognition efficiency was remarkably improved after hydroxyethyl groups were grafted onto chitosan (CS); this might be attributed to the formation of hydrogen bonds between Trp enantiomers and HECS. In addition, the small stereo-hindrance effect could play an important role in enantioselective discrimination.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Xuan Li,Yixin Yun,Yitong Wang,Wanbin Zhu,Quan Bu,Yaxun Fan,Hongliang Wang
Inexpensive biomass materials hold great potential for the development of green delivery systems aimed at improving the extremely low utilization efficiency of pesticides. However, current systems face challenges in achieving both high encapsulation rates and drug loading capacities. This study introduces a novel method using chitosan (CS) and sodium lignosulfonate (SL) to co-assemble with avermectin (AVM), a widely used hydrophobic pesticide, forming AVM-CS-SL micro-nano capsules. Engineered under optimized conditions of pH 5 and 40 °C, the capsules exhibit an AVM encapsulation efficiency of 84.27 % and a loading capacity of 90 %. The AVM-CS-SL capsules demonstrate multifunctional attributes that enhance pesticide application. The capsules, with an average diameter of 356 nm, facilitate stable embedding in leaf grooves and enable effective adhesion to leaf surfaces, thereby improving their resistance to wash-off by rain compared to conventional formulations. Their core-shell structure protects AVM from photodegradation, ensuring long-term stability and efficacy. The capsules also exhibit enhanced bioactivity, with higher mortality rates in Plutella xylostella larvae and low genotoxicity to Vicia faba plants. These findings highlight the strategy of developing multifunctional delivery systems by the co-assembled carrier materials with active ingredients, offering an effective solution for the sustainable development of society and environment.
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高影响因子
ACS Applied Polymer Materials
·
2024
·
IF 4.4
Yanbo Liu,Tianyi Zhang,Bo Yang,Ming Hao,Xiaodong Hu,Xiaoxiao Wang
Piezoelectric devices are becoming increasingly attractive in areas such as wearable electronics, mobile environmental sensors, and health monitoring due to their unique capability to harvest discrete mechanical energy. Nevertheless, most piezoelectric materials are fabricated into low-dimensional products, which limits the performance breakthroughs and application prospects of these devices. Here, a series of polyvinylidenefluoride (PVDF) doped with dopamine hydrochloride@BaTiO3/MXene/chitosan (PVDF-B/MXene/CS) composite aerogel piezoelectric devices with outstanding output performance were fabricated by combining electrospinning and freeze-drying techniques. Among them, the PVDF-B/MXene/CS composite aerogel-based piezoelectric devices with electrodes exhibited rather better output performance compared to those without electrodes, while the electrodeless piezoelectric devices demonstrated excellent piezoelectric response under various stress modes. The electrodeless piezoelectric devices maintained a stable voltage over 1800 cycles and achieved the maximum power output of 4.25 nW with an external resistance of 100 MΩ. Furthermore, the electrodeless piezoelectric device was capable of charging capacitors with varying capacities and could easily illuminate a small light emitting diode (LED) light by manual tapping. These piezoelectric devices showed tangible and stable signals regarding mechanical stimuli monitoring, such as wrist bending, finger tapping, and pedal movements. This work not only expands the range of aerogel-based piezoelectric materials but also showcases their immense potential in the field of piezoelectric devices.
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JOURNAL OF MEMBRANE SCIENCE
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2024
·
IF 8.4
Yinyu Li,Cai Zhang,Jianqing Rao,Xiaogeng Lin,Yasan He
Covalent organic frameworks (COFs) based membranes have demonstrated great potential in molecular separation. However, COFs are usually synthesized as powders, and difficult to form large-area and highly crystalline membranes. There normally exists unfavorable crystal flaws and stacking defects in membranes, impairing their rejection performance. The severe reaction conditions of solvothermal synthesis also inhibit their fabrication. Here, a comprehensive strategy was developed to fabricate a homogeneously assembled COF membrane co-stitched by β-cyclodextrin (β-CD) and chitosan (CS). Specifically, the COF crystallites (named TATP) were homogeneously formed and assembled to be films at room temperature under the control of n-propylamine; The aminated CS chemically bonded the TATP crystallites on the substrate and helped assemble them to form dense films. β-CD molecules were subsequently embedded into the TATP layer and crosslinked to further stitch membrane defects. The prepared CD-TATP-NH 2 CS/nylon membrane demonstrated enhanced excellent rejection performance. It could reject 100 % of R250 (BB), Congo red, Direct blue15, and 99.4 % of Alcian blue. It also could selectively separate Methyl orange (MO) and BB mixed solutions with only MO passing through, owing to the co-stitching of the membrane defects by β-CD and CS. This study provides a significant concept and strategy for fabricating high-performance COF membranes.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Wenhui Chen,Jiayao Wang,Chiyin Zhang,Shaokui Cao,Jingguo Li,Jun Shi
Hollow natural polysaccharide microcapsules have broad applications in drug delivery field due to their excellent biocompatibility and drug loading efficiency. In this paper, pH/near-infrared (NIR) dual-responsive microcapsules composed of hyaluronic acid (HA), chitosan (CS) and hollow CuS (HA/CS/HA@CuS) had been fabricated via a layer-by-layer (LbL) approach. The negative charge, rough surface and hollow structure of microcapsules are very favorable for loading positively charged DOX. As a result, hollow microcapsules display a high drug loading efficiency of 91.15 %. The variation in the degree of amino ionization at different pH values leads to the changes in the electrostatic force between CS/HA multilayers, resulting in the structural change in microcapsules. Therefore, microcapsules exhibit significant pH-responsive drug release properties. In addition, hollow CuS nanoparticles with excellent photothermal conversion ability are capped on the multilayer surface, enabling microcapsules to exhibit excellent NIR-responsive drug delivery properties. Overall, hyaluronic acid/chitosan-based hollow microcapsules with notable pH/NIR dual-responsiveness have been prepared, which can be used as a potential drug carrier for controlled drug delivery and photothermal chemical combination therapy.
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EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
·
2024
·
IF 4.3
Ziming Liu,Sihui Li,Pengfei Xu,Huiqin Gan,Pengfei Yue,Shuying Xie,Zixia Zhang,Weifeng Zhu,Zhiyu Guan
Objective To prepare chitosan-loaded nanoparticles (NPs) that enhance the oral bioavailability of puerarin (Pur) and render it responsive to reactive oxygen species (ROS). Significance This research makes substantial progress towards the theory of intelligent drug delivery, offering a new reference for combining Pur with other natural medicinal active ingredients. Methods The acylation reaction between chitosan and ROS-sensitive 3-carboxyphenylboronic acid (PBA) was used to synthesise ROS-sensitive phenylboronylated chitosan (PBACS). Subsequently, PBACS-PBA-Pur-NPs and PBACS-TPP-Pur-NPs were prepared via ion gelation after the addition of PBA and sodium tripolyphosphate(TPP), respectively. The physicochemical and functional properties of both NPs were compared, and their differences were preliminarily studied through molecular docking. Results Reactive oxygen species-sensitive PBACS was successfully synthesised. Of the two NPs prepared, PBACS-TPP-Pur-NPs had a size of 127.2 ± 0.80 nm, polydispersity index (PDI) of 0.129 ± 0.0008, and an encapsulation rate of 95.75 ± 0.387%, whereas PBACS-PBA-Pur-NPs had a size of 149.8 ± 0.1414 nm, PDI of 0.389 ± 0.0012, and an encapsulation rate of 91.77 ± 0.279%. The micromorphology of the PBACS-TPP-Pur-NPs exhibited better physical properties. However, PBACS-PBA-Pur-NPs demonstrated a faster in vitro release and more significant in vitro anti-inflammatory effects. Pharmacokinetically, the AUC 0-24 , T max , and C max of PBACS-PBA-Pur-NPs were 3.485, 2.117, and 3.339 times higher, respectively, than those of Pur. The AUC 0-24 , T max , and C max of PBACS-TPP-Pur-NPs were 2.41, 1.33, and 2.03 times higher, respectively, than those of Pur. Molecular simulation revealed that the binding energy of PBACS-PBA-Pur -NPs was approximately -4.34 kcal/mol and that of PBACS-TPP-Pur-NPs was even lower, approximately -5.93 kcal/mol, suggesting that the NPs prepared with TPP are more densely packed than those designed with PBA, resulting in slower and reduced drug release. Conclusion The NPs constructed in this study effectively reduced inflammatory factors at the disease site, providing a theoretical and experimental basis for the application of nano drugs in inflammatory disease models. In addition, the molecular docking study of the two NPs offered insights into the relationship between the release and structure of subsequent nano drugs.
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高影响因子
FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Wenbo Miao,David Julian McClements,Zhiheng Zhang,Qianzhu Lin,Hangyan Ji,Jinpeng Wang,Zhengyu Jin,Guanghua Li,Liming Jiang,Jinsheng Wen,Shangyuan Sang,Chao Qiu
The creation of solid fat substitutes using food-grade biopolymers is currently an important focus of food researchers trying to develop healthier food products. In this study, emulsion-templated oleogels assembled from octenyl succinic anhydride starch (OS)-chitosan (CS) electrostatic complexes were prepared. The effects of the OS-CS complexes on the intermediate (emulsion) and final (oleogel) products were investigated. Emulsions stabilized by OS-CS complexes had greater interfacial layer stability and mechanical strength than those stabilized by only OS. The oil loss from the oleogels decreased significantly ( p < 0.05) as the chitosan concentration was raised: from 10.28 to 1.5% oil loss for 0.1–1% CS. The rheological measurements showed that CS incorporation improved the viscoelasticity and thixotropy of the oleogels. In addition, adsorption of the OS-CS complexes inhibited lipid oxidation and hydrolysis due to its compact network and stable interfacial structure. Our results show that OS-CS complexes are effective emulsion-template oleogelators, which may be useful for creating new edible functional materials for application in the food industry.
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Innovative Food Science & Emerging Technologies
·
2025
·
IF 6.8
Yu-Cheng Yang,Shu-Hao Cheng,Yi-Xiong Zhang,Jie Mao,Bing-De Zheng,Na Zhang,Ya-Yan Huang,Xue-Qin Zhang,Jing Ye,Mei-Tian Xiao
To effectively prepare value-added low molecular weight chitosan with improved molecular weight uniformity, a novel high-gravity reactor—the Rotating Foam Stirrer Reactor (RFSR)—is proposed to enhance the chemical degradation process of chitosan. The study reveals that the combined H₂O₂-Vc degradant significantly increases degradation efficiency compared to H₂O₂ or Vc alone, attributed to synergistic effects in hydroxyl radical production. Specifically, the degradation efficiency of the H₂O₂-Vc combination increased by 56.41 % and 32.88 %, respectively, within 5 min. Increased rotational speed improves degradation efficiency and narrows the molecular weight distribution, particularly at higher chitosan concentrations. The weight-average molecular weight rapidly decreases within the first 30 min and then stabilizes, while maintaining a more uniform distribution. Positioning the degradant feed at the stirrer's outer edge further enhances degradation. The RFSR outperforms traditional reactors, producing chitosan with lower molecular weight and better uniformity. Additionally, a predictive correlation for the reaction rate constant, incorporating mass transfer effects, shows good agreement with experimental results, with an error margin of approximately ±20 %, supporting large-scale industrial applications in polysaccharide degradation.
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FERROELECTRICS
·
2024
·
IF 0.6
Chenghong Huang,Xiaorong Huang,Qi Yin,Xuehan Hu,Ying Fang,Hongjie Chen,Lin Zhang,Kang Yang,Hao Li,Fang Yang,Xiaoling Lu,Zeng Yang
Chitosan (CS) is lack of applications in pharmaceutical industry due to its lower compression density and instability during tablet process. This study mainly focus on the synthesis of ethyl vanillin incorporated CS(EV/CS) via Schiff base reaction and the evaluation of application as pharmaceutic excipient. Results of FT-IR showed that there is a typical amide peak in EV/CS that the 1640 cm−1 can be attributed to –C = N– bond and 1518 cm−1 can be attributed to backbone of benzene but not in CS raw material. Compared with the control, XRD of EV/CS have additional 2θ angle of 44°, 64° and 77° diffraction peaks except that the 2θ = 20° of EV is still existed. More slower weight loss of EV/CS than that of CS in the range of 248–760 °C is also demonstrated by TGA analysis. 1H NMR indicated there are intrinsic 7.5 and 7.1 ppm as well as emerging 4.2 ppm of chemical shift in EV/CS. The physical finger spectra from twelve indexes of EV/CS powder denotes quite differences in compressibility, fluidity and stability with that of CS. 5% content EV/CS of designed formulation can at most decrease the friability and disintegration time of the compressed tablet. In conclusion, the developed EV/CS is inclined to suitable for tablet as an excipient.
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危险品化学品经营许可证（带存储）