查找使用阿拉丁产品的科研文献

Ni(OH)2-derived lamellar MoS2/Ni3S2/NF with Fe-doped heterojunction catalysts for efficient overall water splitting

Minghao Dou,Mengjie Yao,Kai Ding,Yuye Cheng,Hongyu Shao,Shenjie Li,Yanyan Chen

Heterostructures formed by combining semiconductor materials with different band structures can provide work functions, d-band positions and electronic properties different from bulk materials and are considered as an effective strategy to improve the catalytic activity through electronic modification. In this study, an efficient MoS2/Fe-Ni3S2/NF heterojunction material was prepared by a two-step hydrothermal method. With the help of flake Ni(OH)2 synthesized in the first step, growth sites were provided for flake Ni3S2. The electronic structure of Ni3S2 was optimized by Fe doping, while the construction of the MoS2/Fe-Ni3S2 heterostructure allowed the catalyst to expose more active sites. MoS2/Fe-Ni3S2/NF exhibited a small charge transfer resistance and excellent electrocatalytic performance. At a current density of 10 mA cm−2, only low overpotentials of 148 mV and 118 mV were required for the oxygen precipitation reaction (OER) and hydrogen precipitation reaction (HER), respectively. Notably, when MoS2/Fe-Ni3S2/NF is used as the anode and cathode for overall hydrolysis, only 1.51 V is required to reach a current density of 10 mA cm−2, demonstrating its great potential for application in hydrolysis. This work provides a feasible idea for the rational construction of non-precious metal bifunctional electrocatalysts with excellent performance.

Tailoring flower-like Zn(OH)2 nanoarchitectures and stearic acid on cellulosic fibers for structurally robust superhydrophobic surface

Chao Li,Tongtong Yun,Gaofeng Pan,Yehan Tao,Jie Lu,Jian Du,Haisong Wang

Structurally robust nanostructures on the surface of matrix highly determine the durability of superhydrophobic surface of cellulosic materials . Traditionally, the hydrophobic inorganic-organic nanocomposites were physically coated on the surface of cellulose fibers , whereas the nanocomposite was easy to fall off under external force due to the weak interfacial interaction between inorganic materials and cellulose, restricting their practical application. In this work, a sort of structurally stable superhydrophobic cellulosic materials was elaborately designed by successive in situ synthesis of Zn(OH) 2 nanoarchitectures and coating stearic acid (STA). The unique flower-like micro/nano structures as well as the presence of hydrophobic STA imparted the cellulosic materials with superhydrophobic behavior and the optimized water contact angle of synthesized STA@Zn(OH) 2 /paper nanocomposite was enhanced to 171°. Moreover, the resultant cellulosic nanocomposite also possesses excellent structural stability without STA and Zn(OH) 2 fall off as well as hydrophobicity reduction after bending 100 times. Compared to bare filter paper, both tensile stress and elongation at break of optimized flower-like nanocomposite reached 14.04 MPa and 25.24% with 109.6% and 323.5% improvement, respectively. Furthermore, such superhydrophobic cellulose-based material also presented excellent anti-fouling and antibacterial performances. This work proposed a facial and efficient strategy to construct structurally stable superhydrophobic cellulose-based materials, displaying great potential application in food packaging and outdoor anti-fouling fields.

Deep Eutectic Solvents Based on L-Arginine and 2-Hydroxypropyl-β-Cyclodextrin for Drug Carrier and Penetration Enhancement

Lv Jianhua,Wu Pan,Fang Yaru,Zhang Wenchang,Liu Dongwen,Wu Mi,Shang Lei,Li Huaiguo,Zhao Yan

By selecting L-arginine as the hydrogen bond acceptor (HBA) and 2-hydroxypropyl-β-cyclodextrin (2HPβCD) as the hydrogen bond donor (HBD), deep eutectic solvents (DESs) with various water content were prepared at the 4:1 mass ratio of L-arginine to 2HPβCD with 40 to 60% of water, and were studied for its application in transdermal drug delivery system (TDDS). The hydrogen bond networks and internal chemistry structures of the DESs were measured by attenuated total reflection Fourier transform infrared (ATR-FTIR) and 1 H-nuclear magnetic resonance spectroscopy ( 1 H-NMR), which demonstrated the successful synthesis of DESs. The viscosity of DES was decreased from 10,324.9 to 3219.6 mPa s, while glass transition temperature (Tg) of the DESs was increased from − 60.8 to − 51.4 °C, as the added water was increased from 45 to 60%. The solubility of ibuprofen, norfloxacin, and nateglinide in DES with 45% of water were increased by 79.3, 44.1, and 3.2 times higher than that in water, respectively. The vitro study of transdermal absorption of lidocaine in DESs showed that the cumulative amounts of lidocaine reached 252.4 µg/cm 2 , 226.1 µg/cm 2 , and 286.1 µg/cm 2 at 8 h for DESs with 45%, 50%, and 60% of water, respectively. The permeation mechanism of DES with lower content of water (45%) was mainly by changing the fluidization of lipids, while changing the secondary structure of keratin in stratum corneum (SC) at higher water content (50% and 60%). These nonirritant and viscous fluid like DESs with good drug solubility and permeation enhancing effects have broad application prospect in the field of drug solubilization and transdermal drug delivery system. Graphical Abstract

CircMEF2C(2, 3) modulates proliferation and adipogenesis of porcine intramuscular preadipocytes by miR-383/671-3p/MEF2C axis

Xiaoyin Rong,Ruixiao Li,Tianye Gong,Haonan Li,Xiaolei Zhao,Guoqing Cao,Meng Li,Bugao Li,Yang Yang,Xiaohong Guo

Circular RNA is a special category of non-coding RNA that has emerged as epigenetic regulator of adipose tissue development. However, the mechanism governing intramuscular adipogenesis of circRNA remains largely uncharted. In this study, circMEF2C(2, 3), looped by MEF2C exons 2 and 3, was identified from the pig MEF2C gene. Expression of circMEF2C(2, 3) is upregulated in early stage of intramuscular adipogenesis and muscular tissue of lean pigs (DLY pig). Subsequently, overexpression or knockdown of circMEF2C(2, 3) reflected that it participates in promoting proliferation and inhibiting adipogenic differentiation in porcine intramuscular preadipocytes and murine C3H10T1/2 cells. Mechanically, circMEF2C(2, 3) competitively combined with miR-383 and miR-671-3p to the 3′-UTR of MEF2C , which maintains MEF2C expression in regulating proliferation and adipogenesis. In summary, circMEF2C(2, 3) is a key regulator in the proliferation and adipogenic differentiation of intramuscular adipogenesis, suggesting its potential as a multi-target strategy for adipose development and associated diseases.

Improved 2∼5 μm mid-infrared fluorescence through energy transfer processes in Er3+/Ho3+ co-doped fluoride glasses

Chuncheng Zhang,Chaomin Zhang,Chao Yun

In this paper, Er 3+ /Ho 3+ co-doped fluoride glasses were prepared by the high temperature melt-quenching technique. Pumped by the 980 nm LD , as a result of the emission spectra overlapping of Er 3+ and Ho 3+ ions, a broadband mid-infrared emission band from 2530 to 2950 nm with a full width at half maximum of the synthetic fluoride glasses near 231 nm was obtained, which exist latent application in wide band tunable mid-infrared fiber laser. Furthermore, the intense 4.1 μm mid-infrared fluorescence (3600–4400 nm) was obtained and the FWHM was 320 nm. The up-conversion emission peaks around 525, 546 and 660 nm, near-infrared emissions at 1.2 and 1.5 μm together with mid-infrared fluorescence around 2.0 μm was observed in Er 3+ /Ho 3+ co-doped fluoride glass. Moreover, the relevant energy transfer processes were discussed in detail based on the emission spectrum and the energy level transition processes. The results indicate that the fabricated Er 3+ /Ho 3+ co-doped fluoride glasses exist prominent emission features for fiber laser gain medium.

Modulating surface electron density of hydrophilic/high-conductive MXene/Ni(OH)2/NF heterostructures for efficient asymmetric supercapacitors

Xinyu Liu,Qianqian Fu,Zhichao Li,Hui Wang,Jianwei Ren

To address the growing demand for efficient and stable energy storage in the context of green energy, in this study, an acid etching method was employed to in-situ grow Ni(OH) 2 nanosheet arrays on a nickel foam (NF) substrate. Subsequently, negatively charged Ti 3 C 2 T x MXene nanosheets were electrophoretically deposited onto the Ni(OH) 2 /NF surface to result in a MXene/Ni(OH) 2 /NF composite electrode material. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) observations revealed the homogeneous dispersion distribution of nanosheets on the material surface. The composite material exhibited high electrical conductivity and good hydrophilicity by rapid water infiltration within 150 ms. Furthermore, the Motte-Schottky effect establishes a distinctive pathway for electron transfer , which leads to the creation of electron vacancies or ‘holes’ on the MXene surface. This phenomenon significantly boosts MXene's electrochemical activity and enhances its affinity for OH − ions in the electrolyte, which consequently improves the performance of electrochemical capacitors . Electrochemical tests verified that the prepared MXene/Ni(OH) 2 /NF electrode displayed an areal specific capacitance of 0.223 mAh cm −2 at a current density of 1 mA cm −2 . The electrode displayed excellent rate performance with a capacity retention rate of 71 % when the current density was increased by five times. In addition, the assembled asymmetric capacitor with MXene/Ni(OH) 2 /NF electrode demonstrated an excellent cycling stability with only a 16.38 % capacity loss after 5000 cycles. It also exhibited the remarkable specific capacitance and long-term stability by achieving a high energy density of 43.68 Wh kg −1 and a power density of 424.96 W kg −1 . These results highlight the electrode's exceptional performance in terms of energy storage and power delivery.

Controlled SPION-Exosomes Loaded with Quercetin Preserves Pancreatic Beta Cell Survival and Function in Type 2 Diabetes Mellitus

Manjiao Zhuang,Lei Rao,Yadi Chen,Shangying Xiao,Haishan Xia,Jiangyong Yang,Xiaohua Lv,Dongyun Qin,Chunjie Zhu

Amide Gemini surfactants linked by rigid spacer group 1,4-dibromo-2-butene: Surface properties, aggregate and application properties

Weiguang Yang,Yupeng Cao,Hongbin Ju,Yakui Wang,Yajie Jiang,Tao Geng

Novel amide Gemini surfactants were synthesized from aliphatic acid amide propyl dimethylamine (PKO-12, 16, 18) and trans-1,4-dibromo-2-butene with one-step reaction. The steady-state surface tension, dynamic surface tension, and interfacial tension of kerosene surfactant solutions of synthesized Gemini surfactants with different hydrophobic chain lengths were studied and compared. Besides, surface tension, and negative staining TEM methods were applied to study the aggregation properties of synthesized Gemini surfactants in the aqueous medium. Also, it was revealed that the Gemini surfactants possess good antistatic and antibacterial properties.

Magnetic-responsive upconversion luminescence resonance energy transfer (LRET) biosensor for ultrasensitive detection of SARS-CoV-2 spike protein

Jiareng Chen,Willis Kwun Hei Ho,Bohan Yin,Qin Zhang,Chuanqi Li,Jiaxiang Yan,Yingying Huang,Jianhua Hao,Changqing Yi,Yu Zhang,Siu Hong Dexter Wong,Mo Yang

Upconversion nanoparticles (UCNPs) are ideal donors for luminescence resonance energy transfer (LRET)-based biosensors due to their excellent upconversion luminescence properties . However, the relatively large size of antibodies and proteins limits the application of UCNPs-based LRET biosensors in protein detection because the large steric hindrance of proteins leads to low energy transfer efficiency between UCNPs and receptors. Herein, we developed a magnetic responsive UCNPs-based LRET biosensor to control the coupling distance between antibody-functionalized UCNPs (Ab-UCNPs) as donors and antibody-PEG linker-magnetic gold nanoparticles (Ab-PEG-MGNs) as acceptors for ultrasensitive and highly selective detection of SARS-CoV-2 spike proteins . Our results showed that this platform reversibly shortened the coupling distance between UCNPs and MGNs and enhanced the LRET signal with a 10-fold increase in the limit of detection (LOD) from 20.6 pg/mL without magnetic modulation to 2.1 pg/mL with magnetic modulation within 1 h. The finite-difference time-domain (FDTD) simulation with cyclic distance change confirmed the distance-dependent LRET efficiency under magnetic modulation, which supported the experimental results. Moreover, the applications of this magnetic-responsive UCNP-based LRET biosensor could be extended to other large-size biomolecule detection.

(E)-2-Octenal suppresses the growth of a prochloraz-resistant Penicillium italicum strain and its potential antifungal mechanisms

Yuwei Luo,Xin Chen,Jin Xin Che,Yonghua Zhang,Qiuli Ouyang,Nengguo Tao

Blue mold caused by Penicillium italicum is one of the most devastating postharvest diseases in Citrus fruit. This work aims to determine the antifungal potential of ( E )-2-octenal, a component of plant essential oil, on the mycelial growth and disease incidence of a prochloraz-resistant strain of P. italicum isolated from an orchard in Luxi, Hunan Province, China. An in vitro assay revealed that the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of ( E )-2-octenal were 0.25 and 0.50 mL L −1 , respectively. An in vivo assay showed that wax + 4 × MFC ( E )-2-octenal treatment could reduce the blue mold incidence in Ponkan fruit inoculated with P. italicum without impairing fruit quality. Scanning electron microscopy analysis illustrated that the mycelia of P. italicum were anomalously twisted and shrunken upon treatment with ( E )-2-octenal. The primary antifungal targets were attributed to the cell membrane instead of the cell wall based on propidium iodide and calcofluor white staining results. In addition, ( E )-2-octenal induced massive accumulation of reactive oxygen species in hyphae in a dose-dependent manner, leading to oxidative stress and dysfunction of energy and respiration metabolism. At the same time, the activities of phosphofructokinase (PFK) and pyruvate kinase (PK) were decreased in ( E )-2-octenal-treated samples. Taken together, our present study suggested that ( E )-2-octenal could exert its antifungal activity against P. italicum by damaging the function of mitochondria and may be a potential antifungal substance for an alternative to chemical fungicides.

Crystal structures, chemical bond, and microwave dielectric properties of Ba1-xKx(Zn1/3Nb2/3)O3-x/2 ceramics

Lei Xiao,Qiang Li,Lianwen Deng,Sen Peng,Tulin Yi,Weichun Liu

Ba 1- x K x (Zn 1/3 Nb 2/3 )O 3- x /2 (BKZN, x  = 0–0.2) ceramics were prepared by the high-temperature solid-state reaction method. Based on P–V–L theory, Raman vibration spectroscopy and X-ray photoelectron spectroscopy (XPS), this paper investigates the relationship between the internal and external factors of K + substitution in the Ba(Zn 1/3 Nb 2/3 )O 3 (BZN) ceramics and the microwave dielectric properties of the ceramics. X-ray diffraction (XRD) characterisation revealed that all samples were single phase with no impure phases. Replacing Ba 2+ with K + greatly reduced the sintering temperature and optimised the microwave dielectric properties of the ceramics. The dielectric constant ( ε r ) was closely related to the ion polarizability and density, and inversely proportional to Raman shift of the A 1g (O) peak. The quality factor ( Q × f ) depended largely on the lattice energy ( U b ) and the full width at half-maximum (FWHM) of A 1g (O) near 790 cm −1 . The temperature coefficient of the resonance frequency ( τ f ) could be inferred from the bond energy ( E b ) and oxygen octahedral distortion. Finally, outstanding microwave dielectric properties ( ε r  = 40.83, Q × f  = 71,658 GHz and τ f  = 2.52 ppm/°C) were acquired for Ba 0.95 K 0.05 (Zn 1/3 Nb 2/3 )O 2.975 ceramics sintered at the optimum sintering temperature (1325 °C) for 4 h.

Directly and ultrasensitivity detecting SARS-CoV-2 spike protein in pharyngeal swab solution by using SERS-based biosensor

Yansheng Liu,Zhenle Qin,Xiaobo Jia,Jin Zhou,Hongli Li,Xiaohong Wang,Yating Chen,Junpeng Deng,Zhicheng Jin,Guofu Wang

The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a great disaster to the economy and human society. Nowadays, SARS-CoV-2 is fading away from people’s memory but it still exists around us. PCR plays an important role in detecting SARS-CoV-2 but it requires a long detecting time, equipped laboratory, and professional operators. In comparison with polymerase chain reaction (PCR), surface-enhanced Raman scattering (SERS) is a promising method for detecting SARS-CoV-2 due to its fast, easily operated, and high-sensitivity properties. In this study, the monolayer Ag nanoparticles (MAgNPs) covered with single-layer graphene (SLG) are applied as a SERS substrate. The angiotensin converting enzyme 2 (ACE2) is selected as a bio-probes that can specifically bind to the SARS-CoV-2 S protein. The SERS-based biosensor is formed by ACE2 functionalized SLG/MAgNPs and the LODs of detecting SARS-CoV-2 S protein in phosphate-buffered saline (PBS) and in pharyngeal swabs solution (PSS) are 0.1 fg mL −1 and 10 fg mL −1 , respectively. This biosensor provides a way of directly detecting SARS-CoV-2 S protein with high sensitivity and specificity. It illustrates a practical potential in the rapid detection of the SARS-CoV-2 virus.