NEW JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 10
·4570-4579
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IF 2.7
Nana Li,Yuncong Yang,Balaji Murugesan,Yong Zhang,Zhuo Chen,Xiaogang Yang,Yurong Cai
To achieve a conductive hydrogel with favourable mechanical and electrical properties, an oriented Mxene-SNF (MSNF) conductive hydrogel was developed using the directional freezing technique. This process involved combining silk fibroin nanofibers (SNF) rich in β-sheet structures with MXene nanosheets to establish an oriented internal cross-linked network. The study investigated the influence of various factors on the hydrogel's mechanical and electrical properties. Results demonstrated that the hydrogel's mechanical properties were influenced by SNF content, MXene content and internal structure. Optimal mechanical properties and favourable electrical conductivity were achieved when the SNF mass fraction was 10%, the MXene mass fraction was 10%, and the internal structure was oriented. The obtained oriented MSNF hydrogel displayed a tensile strain of 80% ± 3%, a tensile stress of 0.89 ± 0.03 MPa, and an elastic modulus of 3.41 ± 0.05 MPa, roughly twice that of the human forearm skin. It maintained a stable resistance response at 0–70% tensile strain. To demonstrate its stability and durability, the hydrogel underwent 500 cycles within the 30–50% tensile strain interval. Therefore, the conductive hydrogel exhibits the potential to be attached to different parts of the human body for real-time monitoring of human movement. Its strain-sensing potential holds value in the field of flexible wearable sensors.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Bowen Duan,Hongting Liu,Xiaoxuan Ji,Jingwen Dong,Xinping Luo,Feiran Zhang,Minjie Sun,Zhanwei Zhou
Osteosarcoma is one of the commonest malignant bone tumors in children and adolescents, and its preferred treatment is chemotherapy. However, the lack of sufficient blood vessels in the bone tissue and the dense collagen fibers in osteosarcoma severely weaken the drug-directional accumulation effect and intra-tumoral penetration, leading to poor therapeutic efficacy. Herein, we reported a bone-targeted permeable nanomicelle (Co1-PTX@DSAA) composed of aspartic acid (Asp)-modified dextran (DSAA) to deliver paclitaxel (PTX) and collagenase 1 (Co1) simultaneously for highly effective osteosarcoma treatment. The prepared nanomicelle possessed excellent osteosarcoma targeting ability as Asp can combine with hydroxyapatite (HAP) in bone. More intelligently, the surface-absorbed Co1 endowed PTX@DSAA with a special function like a nano-icebreaker, which could quickly destroy the collagen fibers to promote PTX penetration deeply in the tumor. Our work suggests that Co1-PTX@DSAA nanomicelles could quickly combine with HAP and Ca 2+ at an adsorption rate of ∼ 60% and ∼ 32%, respectively. Meanwhile, the penetration depth of Co1-PTX@DSAA could even reach 70 μm in the multicellular spheroids (MCSs) model. The tumor treatment efficiency of Co1-PTX@DSAA is 1.51 times that of free PTX. Overall, this unprecedented nanomicelle can simultaneously facilitate drug accumulation and deep penetration in the tumor, which will provide a promising strategy for future safe and high-efficiency clinical osteosarcoma treatment.
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ACS Applied Polymer Materials
·
2024
·
IF 4.4
Ye Sun,Wanying Yang,Yunfei Wang,Fan Yang,Xiunan Li,Yanhua Yang,Dong Jiang
Nanofiltration is seen as a potential technique for desalination and purification of drinking water. Improving water permeability without compromising on the high rejection rate in nanofiltration membranes is a major challenge. This article describes interfacial polymerization (IP) mediated by tannic acid (TA)–MXene interlayer to prepare an ultrathin film composite membrane (TFCi) possessing negative surface charge and optimized water transport channel. Nanofiltration process and the formation of the polyamide surface layer are both dependent on the TA–MXene intermediate layer. It is capable of storing amine monomer, decelerating interfacial polymerization, and producing a 30-nm-thick polyamide selective layer devoid of defects. With a rejection rate of 96.0% for divalent ions and a permeation flux of 22.3 L m–2 h–1 bar–1, the nanofiltration membrane that was acquired exhibits exceptional performance and stability in the operation of long-term nanofiltration. In contrast to traditional TFC membranes, the TFCi membrane successfully overcomes the long-standing contradiction between permeability and selectivity. This study offers a straightforward method for fabricating TFC membranes that exhibit outstanding performance.
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ADVANCED FUNCTIONAL MATERIALS
·
2020
·Vol. 31
·期 2
·2001867
·
IF 16.836
Ruirui Zhao,Ying Yang,Ganxiong Liu,Renjie Zhu,Jingbo Huang,Zhiyuan Chen,Zhonghui Gao,Xiao Chen,Long Qie
With advantages such as high theoretical capacity, low cost, and nontoxicity, Zn metal has been widely investigated as an anode for aqueous batteries. However, the problems of dendrite formation and sustained corrosion originating from severe interfacial side reactions and uncontrolled Zn electrodeposition in aqueous electrolytes significantly slows down the practical application of Zn metal anodes. To address these issues, herein, an anti-corrosion elastic constraint (AEC) is introduced that is built with nanosized TiO 2 and polyvinylidene fluoride (PVDF) matrix to Zn anode, where the PVDF layer serves as an elastic H 2 O/O 2 -blocking layer and the decorated TiO 2 nanoparticles assist uniform Zn electrodeposition. With this corrosion-inhibition and electrodeposition-redirection coating, the electrodeposition consistency and thermodynamic stability of the Zn anode are significantly improved, enabling a long-term stable plating/stripping performance for 2000 h with an ultralow overpotential (<50 mV) and a high average Coulombic efficiency (>99.4%) for 1000 cycles without obvious dendrite formation. Even at a high current density of 8.85 mA cm −2 with limited Zn supply (DOD Zn = 60%), stable Zn deposition is achieved over 250 h. When coupled with a MnO 2 cathode, the AEC-Zn anode shows a remarkably enhanced full-cell cycling stability, indicative of high reliability of aqueous Zn batteries for practical application.
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Journal of Coatings Technology and Research
·
2024
·
IF 2.3
Yu Tianlong,Song Gendi,Tian Wenjie,Liu Tingting,Yan Mengying,Wu Bei,Lu Shixiang
Superwetting materials play a crucial part in the fields of chemistry and materials science and draw increasing attention. Among the various applications, superwetting materials demonstrated up-and-coming potential in oil spill remediation. Herein, we report on the preparation of silver-coated copper mesh via a facile chemical deposition and annealing treatment approach that requires neither complex devices nor modification with toxic organic molecules. The resulting sample exhibited remarkable water repulsion (water contact angle of ~ 158° and sliding angle of ~ 1°) and oil affinity (oil contact angle of ~ 0°), contributing to superior separation ability toward various oil–water mixtures (hexane, toluene, benzene, chloroform, tetrachloromethane, kerosene, gasoline, diesel) or effectively cleaning up the floating or underwater oil spill. Moreover, the resulting silver-coated superhydrophobic/superoleophilic copper (Ag-coated SS Cu) mesh demonstrated great durability upon the water flow impact or the abrasion test and was able to continuously separate the toluene–water mixtures over 20 times with an efficiency over 97%. In addition, the sample readily prevented surface fouling via self-cleaning process and exhibited antibacterial ability toward Escherichia coli , Staphylococcus aureus , and Bacillus subtilis as witnessed by the corresponding bacteriostatic circle (11.38 ± 0.76 mm, 12.65 ± 0.68 mm, and 12.87 ± 0.72 mm, respectively) in the Petri dish.
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JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
·
2024
·
IF 3.6
Chengzhi Wang,Dayang Jiang,Huipeng Ge,Jianping Ning,Xia Li,Mingmei Liao,Xiangcheng Xiao
Anticoagulation treatment for patients with high bleeding risk during hemodialysis is challenging. Contact between the dialysis membrane and the blood leads to protein adsorption and activation of the coagulation cascade reaction. Activated coagulation Factor X (FXa) plays a central role in thrombogenesis, but anticoagulant modification of the dialysis membrane is rarely targeted at FXa. In this study, we constructed an anticoagulant membrane using the polydopamine coating method to graft FXa inhibitors (apixaban and rivaroxaban) on the membrane surface. Attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and atomic force microscopy (AFM) were used to characterize the membranes. The apixaban- and rivaroxaban-modified membranes showed lower water contact angles, decreased albumin protein adsorption, and suppressed platelet adhesion and activation compared to the unmodified PES membranes. Moreover, the modified membranes prolonged the blood clotting times in both the intrinsic and extrinsic coagulation pathways and inhibited FXa generation and complement activation, which suggested that the modified membrane enhanced biocompatibility and antithrombotic properties through the inhibition of FXa. Targeting FXa to design antithrombotic HD membranes or other blood contact materials might have great application potential.
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PubMed
高影响因子
Nano-Micro Letters
·
2024
·Vol. 16
·期 1
·1-24
·
IF 31.6
Ren Junji,Zhang Zibin,Geng Shuo,Cheng Yuxi,Han Huize,Fan Zhipu,Dai Wenbing,Zhang Hua,Wang Xueqing,Zhang Qiang,He Bing
Achieving increasingly finely targeted drug delivery to organs, tissues, cells, and even to intracellular biomacromolecules is one of the core goals of nanomedicines. As the delivery destination is refined to cellular and subcellular targets, it is essential to explore the delivery of nanomedicines at the molecular level. However, due to the lack of technical methods, the molecular mechanism of the intracellular delivery of nanomedicines remains unclear to date. Here, we develop an enzyme-induced proximity labeling technology in nanoparticles (nano-EPL) for the real-time monitoring of proteins that interact with intracellular nanomedicines. Poly(lactic-co-glycolic acid) nanoparticles coupled with horseradish peroxidase (HRP) were fabricated as a model (HRP(+)-PNPs) to evaluate the molecular mechanism of nano delivery in macrophages. By adding the labeling probe biotin-phenol and the catalytic substrate H 2 O 2 at different time points in cellular delivery, nano-EPL technology was validated for the real-time in situ labeling of proteins interacting with nanoparticles. Nano-EPL achieves the dynamic molecular profiling of 740 proteins to map the intracellular delivery of HRP (+)-PNPs in macrophages over time. Based on dynamic clustering analysis of these proteins, we further discovered that different organelles, including endosomes, lysosomes, the endoplasmic reticulum, and the Golgi apparatus, are involved in delivery with distinct participation timelines. More importantly, the engagement of these organelles differentially affects the drug delivery efficiency, reflecting the spatial–temporal heterogeneity of nano delivery in cells. In summary, these findings highlight a significant methodological advance toward understanding the molecular mechanisms involved in the intracellular delivery of nanomedicines.
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PubMed
高影响因子
Friction
·
2024
·
IF 6.3
Deng Haoyu,Yu Tongtong,Du Changhe,Shen Ruilin,Zhao Yongkang,He Xinjian,Feng Yange,Zhang Liqiang,Wang Daoai
Ultra-low friction is crucial for the anti-friction, anti-wear, and long-life operation of nanodevices. However, very few two-dimensional materials can achieve ultra-low friction, and they have some limitations in their applications. Therefore, exploring novel materials with ultra-low friction properties is greatly significant. The emergence of ternary two-dimensional materials has opened new opportunities for nanoscale ultra-low friction. This study introduced nickel phosphorous trisulfide (NiPS 3 , referred to as NPS), a novel two-dimensional ternary material capable of achieving ultralow friction in a vacuum, into the large nanotribology family. Large-size and high-quality NPS crystals with up to 14 mm × 6 mm × 0.3 mm dimensions were grown using the chemical vapor transport method. The NPS nanosheets were obtained using mechanical exfoliation. The dependence of the NPS nanotribology on layer, velocity, and angle was systematically investigated using lateral force microscopy. Interestingly, the coefficient of friction (COF) of NPS with multilayers was decreased to about 0.0045 under 0.005 Pa vacuum condition (with load up to 767.8 nN), achieving the ultra-low friction state. The analysis of the frictional dissipation energy and adhesive forces showed that NPS with multilayers had minimum frictional dissipation energy and adhesive forces since the interlayer interactions were weak and the meniscus force was excluded under vacuum conditions. This study on the nanoscale friction of a ternary two-dimensional material lays a foundation for exploring the nanoscale friction and friction origin of other two-dimensional materials in the future.
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GEOFLUIDS
·
2024
·Vol. 2024
·期 1
·9112308
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IF 1.2
Hongmei Li,Yun Zhao,Jie Deng,Jing Xie,Weiqi Zhou,Yiting Liu,Luming Li,Futing Xia,Rui Qi
The optimization of coal dust management in fluidized mining environments is of paramount importance, yet it is currently impeded by a gap in understanding chemical dust suppression mechanisms. This study combines indoor experiments with molecular simulation to investigate the mechanisms by which three anionic surfactants with different hydrophilic and hydrophobic groups (SDBS, SDS, and SLS) influence coal wettability. Using hydrophobic bituminous coal as the experimental subject, basic physical and chemical properties are analyzed through proximate analysis, XRD, and FTIR. The effect of different surfactants on coal wettability is characterized based on sedimentation experiments, while the coal–surfactant–water three-phase model examines the equilibrium adsorption configuration, water molecule diffusion coefficient, and interaction energy in different adsorption systems. The surface free energy of coal dust and its components is measured before and after surfactant adsorption, verifying the adsorption-wetting mechanism of surfactants at the coal–water interface. Results show that anionic surfactants enhance wettability through a bidirectional adsorption mechanism at the coal–water interface: the hydrophobic tail adheres to the coal surface via van der Waals forces, while the hydrophilic head faces the water phase, driven by electrostatic and hydrogen bonding interactions. This coordinated adsorption process alters water diffusion and the surface free energy of coal, thereby improving wettability. SDBS, due to its benzene ring, significantly amplifies the bidirectional adsorption effect, achieving the most substantial improvement in coal dust wettability. The findings provide a robust theoretical framework for developing dust control strategies in fluidized mining operations, advancing the field toward more efficient and sustainable mining practices.
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Science Advances
·
2025
·Vol. 11
·期 12
·
IF 12.5
Xiaoran Zhang,Yanhong Lyu,Jingjing Ding,Xin Wang,Bernt Johannessen,San Ping Jiang,Jianyun Zheng
l-phenylalanine (l-Phe), an essential amino acid for humans, is widely used as building blocks. Currently, l-Phe is obtained via biosynthetic methods including microbial and enzymatic processes, but their tightly complex feedback regulation and lengthy reaction steps lead to a low practical yield of l-Phe. Here, we have designed a hierarchical Si-based photocathode for l-Phe synthesis by photoelectrochemical coupling of waste CO2 and nitrophenyl ethane, achieving a high yield rate of 37.5 μg·hour−1·cm−2 and a remarkable Faradaic efficiency of 21.2% at low applied potential under 1 sun illumination. The hierarchical structure with CuO-TiO2-C mixtures dispersed in amorphous TiO2 layer/n+p-Si creates an internal built-in electric field and forms plentiful conducting channels to efficiently realize the injection of electrons into Cu and Ti sites. These Cu and Ti sites adsorb and activate the CO2 and nitrophenyl ethane, respectively, cooperatively facilitating the l-Phe synthesis. This work introduces an environmentally friendly and highly efficient approach for converting solar energy into valuable amino acid products.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Shunyu Xiang,Jing Wang,Yang Shen,Xingyi Luo,Xiaoyan Wang,Changyun Liu,Xinyu Chen,Hüseyin Enis Karahan,Jin Huang,Alberto Bianco,Xianchao Sun
Manganese is vital for plant growth and disease resistance but remains underutilized as a bioactive agent due to its toxicity at high concentrations. Here, an effective antiviral nanopesticide system utilizing Mn ions (Mn 2+ ) within safe limits is described. Briefly, cellulose nanocrystals (CNCs) are employed as bio-sourced carrier surfaces and polydopamine (PDA) as a stabilizing and chelating agent for Mn 2+ . By impregnating Mn 2+ onto PDA-coated CNCs, the stable CNC@PDA@Mn 2+ (CPM) composite is fabricated. The CPM composite exhibits a substantially strengthened inhibitory effect on virus infectivity and curtails virus accumulation in Nicotiana benthamiana . The synergistic effects of CPM stem from its ability to directly disrupt viral particles and activate the plant-immunity-related antioxidant systems. Additionally, H 2 O 2 generated by the CPM-activated superoxide dismutase potentially serves as a molecular signal to overexpress the disease-resistance gene harpin-induced 1 ( NbHin1 ) by sulfinylating CCA1 Hiking Expedition and enhance its binding to NbHin1 promoter. Subsequently, this upregulation coordinates the activation of NbHin1 -dependent macroautophagy, triggering multiple antiviral defense mechanisms. Thus, this design achieves highly potent broad-spectrum antiviral activity at low concentrations of manganese (16 µg mL −1 ). Notably, this work pioneers the use of Mn 2+ in triggering plant antiviral defense, offering a solid foundation for designing novel antiviral agents.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Xing Lai,Weiye Xu,Yukui Gou,Hongxiang Zhang,Jianying Huang,Weilong Cai,Yuekun Lai
Phytate (PhA) holds considerable promise for constructing molecular sieve membranes due to its high density of long-range electrostatic attractions, customizable charge density, and excellent polymer affinity. Herein, PhA-Fe 3+ complexes constructed by controllable coordination assembly are presented, based on metal-organophosphorus biphasic interfacial coordination reactions, and use the PhA-Fe 3+ complexes to regulate the interfacial polymerization (IP) process to generate polyamide (PA) nanofiltration membranes. The PhA-Fe 3+ complexes impart a high density of long-range electrostatic and short-range hydrogen bonding forces to the amine monomers and provide tunable charge densities through flexible metal-organophosphate coordination. Hydrogen bonding and strong electrostatic interactions spatially enrich the amine monomers and temporally slow down their diffusion into the hexane phase, as demonstrated by molecular simulations, resulting in a PA/PhA-Fe 3+ membrane with increased surface area, enhanced microporosity, lower thickness, higher water density near pores, and nanoscale spotted structures. Those structures are recognized as the key factor in achieving a water permeance of 19.2 L m −2 h −1 bar −1 , alongside a MgCl 2 rejection of 96.7% and a Li + /Mg 2+ selectivity of 24.1 (Mg 2+ /Li + mass ratio = 20), surpassing those of reported nanofiltration membranes. This PhA-Fe 3+ complexes-modulated IP strategy offers fresh perspectives for constructing a highly permeable membrane for lithium extraction from salt lake brines. Graphical Here, PhA-Fe 3+ complexes are synthesized through metal-organophosphorus biphasic interfacial coordination to modulate interfacial polymerization, yielding polyamide nanofiltration membranes. Molecular simulations confirm that hydrogen bonding and electrostatic interactions spatially confine amine monomers while retarding their diffusion into hexane, endowing such ultrathin PA/PhA-Fe 3+ membrane with enhanced microporosity, enlarged surface area, nanoscale spotted morphology, and optimized hydration layer density at the pore interfaces. The optimized membrane exhibits high permeability and stable Li + /Mg 2+ selectivity.
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