Materials Science & Engineering C-Materials for Biological Applications
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2020
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IF 5.88
Xuan Liu,Chen Wang,Xueyan Wang,Chen Tian,Yuhua Shen,Manzhou Zhu
Designing a proper intelligent platform to target cancer cells accurately and reducing its toxic side effects on normal tissues remain a challenge in medicine application. Herein, a novel dual-targeted and tumor microenvironment-triggered Fe 3 O 4 @carbon(C)/ZnO-doxorubicin (DOX) -folic acid (FA) drug delivery system with porous structure was designed and fabricated for the first time. The co-presence of Fe 3 O 4 core and FA molecules functioned successfully could successfully realize the magnetic targeting and cancer cell-specific targeting. In addition, pH-responsive ZnO and porous carbon both derived directly from zinc-2-methylimidazolate complex (Zn-ZIF) could play the roles of “gatekeeper” and photothermal agent, respectively. The former could efficiently block the drug within mesoporous in blood environment for decreasing the damage to the normal tissues and achieving the controlled DOX release in the simulated and real acidic tumor microenvironment. And the latter could exhibit the intrinsic photothermal conversion efficiency upon 638 nm laser irradiation. Therefore, the Fe 3 O 4 @C/ZnO-DOX-FA nanoplatform integrated dual targeting, controlled chemotherapy with photothermal therapy (PTT) for cancer, displaying a significantly superior synergistic anticancer efficiency both in vitro and in vivo experiments to either monotherapy. Above results suggested the prepared nanoplatforms might be a promising candidate for effectively synergetic therapeutics to cancers.
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高影响因子
ACS Applied Nano Materials
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2020
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IF 0
Kun Li,Yoann de Rancourt de Mimérand,Xiaoyun Jin,Jungang Yi,Jia Guo
Hybrid nanomaterials have been produced using a combination of core–shell synthesis, 3D printing, and plasma grafting. Metal oxides, that is, ZnO and TiO2, as well as iron-based metal organic frameworks (Fe-MOF) nanoparticles were grafted permanently onto the surface of 3D-printed fractal substrates via cold plasma discharge (CPD). The aim is to produce supported photocatalysts for the degradation of organic pollutants in water. Herein, different plasma grafting strategies are developed, namely direct (using core–shell prefunctionalization) and indirect grafting. Noticeably, the latter, using poly(vinylphosphonic acid) as an intermediate layer for self-assembly grafting, potentially opens the way for the functionalization of any polymeric surface by inorganic nanocompounds. This study mainly aims at giving insight into the plasma immobilization process, but also demonstrating the potential it offers in the domain of supported catalysis. The activity of the different hybrid materials has been assessed by monitoring the photodegradation of Rhodamine B dye (ZnO and TiO2) and the removal of Ciprofloxacin antibiotic (Fe-MOF). Also, the reusability of the hybrid photocatalysts has been demonstrated. Independently, it was found that modifying the surface of the metal oxide nanoparticles with organic coupling agents—aiming at their plasma-grafting immobilization on polymer supports—allowed enhancing their photodegradation efficiency up to 20%. Finally, a resin fractal support has been printed by liquid crystal diode-based SLA (stereolithography) and later surface-functionalized by Fe-MOF nanoparticles. This provides evidence to the possibility of using laser-based 3D printing technologies to produce supports with high surface area for the immobilization of catalysts by plasma grafting.
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ANALYTICA CHIMICA ACTA
·
2020
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IF 5.977
Yingcong Zhang,Ze Zhang,Shengzhong Rong,Hongwei Yu,Hongmin Gao,Qian Sha,Ping Ding,Hongzhi Pan,Dong Chang
An ultrasensitive sandwich-type electrochemiluminescence (ECL) immunosensor was developed for detection of prostate specific antigen (PSA) using an amplification strategy based on ZnO nanorods- l -cysteine-luminol nanocomposites and the biotin-streptavidin system. The biotin-streptavidin system served as a capture probe to increase the number of antibodies. ZnO nanorods not only acted as a nanocarrier that increased the number of luminol molecules and secondary antibodies, but also enhanced the ECL signal of luminol-H 2 O 2 system by promoting H 2 O 2 decomposition, which can further increase ECL intensity. Under optimized conditions, the proposed immunosensor demonstrated excellent analytical performance with a wide linear detection range of 0.03 pg mL −1 to 30 ng mL −1 and a detection limit of 0.01 pg mL −1 (the detection limit in real samples was 0.021 pg mL −1 ). This method exhibited excellent stability, reproducibility, and selectivity. In addition, the results of PSA determinations in human serum samples obtained using the proposed immunosensor were consistent with data collected using the commercial chemiluminescence immunoassay analyzer.
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高影响因子
NANOTECHNOLOGY
·
2020
·Vol. 31
·期 28
·285402
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IF 3.551
X T Zhang,Y F Yuan,M Zhu,G C Cai,Z W Tong,Z Y Yang
Low electronic conductivity and large volume variation result in inferior lithium storage performance of ZnO. To overcome these shortcomings of ZnO, herein ZnO nanoparticles are encapsulated in resorcinol–formaldehyde resin-derived hard carbon and then further assembled into a 3-dimensional mesoporous framework structure using a polyvinyl pyrrolidone-derived soft carbon network. The synthesis methods include the polymerization of resorcinol–formaldehyde resin and a polyvinyl pyrrolidone-boiling method. ZnO@dual carbon has af large specific surface area (153.7 m2 g−1) and high porosity. It exhibits excellent cycling performance and high rate capability. After 350 cycles at 500 mA g−1, the ZnO@dual carbon still delivers a discharge capacity of 701 mAh g−1 while the actual discharge capacity of ZnO reaches 950.9 mAh g−1. At 2 A g−1, ZnO@dual carbon delivers the average discharge capacity of 469.6 mAh g−1. The electrochemical performance of ZnO@dual carbon is remarkably superior to those of ZnO@single carbon, pure carbon and pure ZnO nanoparticles, demonstrating the superiority of the dual carbon-assembly structure. This composite structure greatly improves the structural stability of ZnO, enhances its electron conductivity and overall electron transport capacity; which facilitates electrolyte penetration and Li ion diffusion, leading to improved cycling stability and good rate capability.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2020
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IF 4.65
Tong Zou,Xinxin Xing,Yue Yang,Zhezhe Wang,Zidong Wang,Rongjun Zhao,Xu Zhang,Yude Wang
Copper, as an essential element in human body, can have adverse impact on environment and healthy individuals if it is excessive. So it is necessary to establish a rapid and effective method for detecting Cu 2+ . In this work, we describe a method for determination of Cu 2+ based on water-soluble ZnO quantum dots (QDs) modified with (3-aminopropyl)triethoxysilane (APTEs). The ZnO QDs functionalized with APTEs (NH 2 –ZnO QDs) synthesized by a simple sol-gel method and displayed strong yellow-green fluorescence with a peak at 535 nm under 350 nm excitation. High-resolution transmission electron microscopy, Fourier transform infrared spectroscopy , luminescence, and UV–visible absorption spectroscopy were used to characterize the NH 2 –ZnO QDs. In addition, the emission from NH 2 –ZnO QDs was selectively quenched upon addition of Cu 2+ . Therefore, this finding was used to design a fluorescent probe based on NH 2 –ZnO QDs to detect Cu 2+ in water solution, and the linear relationships were 2–20 nM and 1–100 μM respectively, with detection limit for Cu 2+ at 1.72 nM (on the basis of 3σ/slope criterion). This fluorescent probe had also been applied in real water sample to testify its availability in drinking water. Furthermore, the quenching mechanism was studied by measurements of UV–visible absorption spectra and fluorescent lifetime of ZnO QDs, which may be attributed to the aggregation induced by Cu 2+ and the dynamic quenching existing energy transfer between QDs and Cu 2+ .
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ANALYTICA CHIMICA ACTA
·
2019
·
IF 5.256
Kang Zou,Yamin Fu,Ruiying Yang,Xiaohua Zhang,Cuicui Du,Jinhua Chen
By direct calcination of Cu 2+ -doped ZIF-8 in oxygen atmosphere, a new photoelectric material, CuO–ZnO heterojunction , was prepared. The morphology and structure were investigated in detail by several methods, such as scanning electron microscopy, transmission electron microscopy , nitrogen adsorption-desorption method and X-ray diffraction. Under visible light irradiation , CuO–ZnO heterojunction exhibits excellent PEC behavior in aqueous media with the presence of ascorbic acid (AA) and dissolved oxygen at −0.3 V. Taking the CA125-antibody functionalized CuO–ZnO heterojunction (CuO–ZnO-Ab 2 ) as a signal source, a novel photoelectrochemical (PEC) immunosensing platform was developed for ultrasensitive assay of CA125. Because of the target-induced introduction of photoelectric material to the sensing platform, the proposed PEC immunosensor has excellent performance for CA125 assay: near-zero background noise, wide linear response range (1 × 10 −5 U/mL to 100 U/mL) and low detection limit (3.16 × 10 −6 U/mL). The developed CuO–ZnO heterojunction and the related PEC sensing platform may have promising applications in ultrasensitive and highly accurate monitoring of various proteins in bioanalysis and disease diagnosis.
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Energy Storage Materials
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2018
·
IF 0
Gaozhan Liu,Dongjiu Xie,Xuelong Wang,Xiayin Yao,Shaojie Chen,Ruijuan Xiao,Hong Li,Xiaoxiong Xu
A series of new solid electrolytes of Li 3+3 x P 1- x Zn x S 4- x O x ( x = 0.01, 0.02, 0.03, 0.04, 0.05, 0.06) are synthesized successfully via Zn, O co-doping the Li 3 PS 4 glass-ceramic for the first time. The result shows that Li 3 PS 4 aliovalent substitution of 2 mol% ZnO (Li 3.06 P 0.98 Zn 0.02 S 3.98 O 0.02 ) presents the highest conductivity of 1.12×10 −3 S cm −1 at room temperature, which is twice that of the pristine Li 3 PS 4 . Besides, Li 3.06 P 0.98 Zn 0.02 S 3.98 O 0.02 exhibits excellent stability against humid air , lithium metal and chlorobenzene solvent. The mechanisms of the enhancement of conductivity and air-stability are well understood by conducting first-principles density functional theory (DFT) calculation and Bond-Valence (BV) analysis, and the results well demonstrate that the conductivity and air-stability of Li 3 PS 4 could be improved via Zn, O dual-doping, in which partial P 5+ could be substituted by Zn 2+ , and a part of S 2- could be replaced by O 2- . Finally, the all-solid-state lithium battery (ASSLB) with bi-layer electrolytes of LiCoO 2 /Li 10 GeP 2 S 12 /Li 3.06 P 0.98 Zn 0.02 S 3.98 O 0.02 /Li is assembled, and it delivers an initial discharge capacity of 139.1 mAh g −1 at 0.1 C and a capacity retention of 81.0% after 100 cycles at room temperature. This work combines systematical experimental characterizations and sufficient theoretical calculations to develop a new promising sulfide electrolyte with superior lithium ion conductivity and high air-stability for ASSLBs application.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2018
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IF 11.698
He Xiao,Wenyao Zhang,Qiushi Yao,Liulian Huang,Lihui Chen,Bruno Boury,Zhongwei Chen
Metal organic frameworks (MOFs) are exploited in many applications of materials science and very recently were investigated as precursors or reagents for material synthesis. In a new way different from previous approaches, here we introduce for the first time the synthesis of metal oxide M x O y in the presence of M-free MOF acting partially as a sacrificial template and as a provider of doping metal atom. We demonstrate this approach in the case of ZnO prepared by a simple hydrothermal method in the presence of a Zn-free MOF like MIL-53(Al) or MIL-125(Ti). The resulting ZnO show low content of Al or Ti < 2% and properties are significantly different depending on whether MIL-53(Al) or MIL-125(Ti) are used or if no MOF is present. The nature and presence of MOF has different major effects on the morphology, the specific surface area of as prepared ZnO and also on the oxygen defects in its crystal structure. Corroborating the XPS, UV–vis DRS, PL, EPR and DFT studies evidence the role of such O-defects on band gap narrowing for samples calcined at 400 °C. These exhibit high efficiency in photodegradation of methyl orange (MO) compared to ZnO prepared in MOF-free conditions or previous literatures. The kinetics of MO degradation is different depending on the morphology, the specific surface and oxygen defects. The present data open the door to a new approach of the synthesis of metal oxides and a control of their properties.
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ELECTROCHIMICA ACTA
·
2013
·
IF 3.777
Xingtian Yin,Wenxiu Que,Duan Fei,Haixia Xie,Zuoli He
TiO 2 shell layer on the surface of ZnO nanowires (NWs) was synthesized by a layer by layer adsorption and reaction (LBLAR) method. Scanning electron microscopy image shows that the prepared ZnO–TiO 2 core–shell NW arrays have a similar morphology with the well-aligned ZnO core NW arrays, providing the LBLAR cycles is controlled within a certain number. The prepared ZnO–TiO 2 core–shell NW arrays were sensitized with CdS quantum dots to assemble quantum dots sensitized solar cells. Results indicate that a dramatic increase in open-circuit voltage and fill factor is achieved with an introduction of the TiO 2 shell layer with a thickness of about 7 nm, resulting in a substantial improvement of the overall energy conversion efficiency. A rapid electron transfer from the CdS QDs to the ZnO NWs and a reduced electron recombination rate due to the energy barrier occurred at the interface between the ZnO core and the TiO 2 shell are believed to contribute to the improved performance of the solar cells based on the ZnO–TiO 2 core–shell NW arrays. In addition, effects of the TiO 2 shell thickness on the performance of the as-fabricated devices are also discussed in detail.
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JOURNAL OF POWER SOURCES
·
2013
·
IF 4.675
Siyao Guo,Song Han,Haifeng Mao,Shimiao Dong,Congcong Wu,Lichao Jia,Bo Chi,Jian Pu,Jian Li
A versatile synthetic method, which is based on a low-temperature hydrothermal technique, is developed for the fabrication of a microporous ZnO/TiO 2 composite catalyst with different structures (e.g., amorphous , amorphous/crystalline and crystalline). In particular, a novel microporous ZnO/TiO 2 composite with amorphous/crystalline structure is obtained with a 3/1 M ratio of Ti/Zn. This novel ZnO/TiO 2 composite heterostructure not only has a large specific surface area (311.9 m 2 g −1 ) but also exhibits outstanding performance during solar water splitting reactions to generate hydrogen without a noble metal co-catalyst. Based on our in-depth mechanistic analysis, the synergistic effect between the amorphous ZnO and crystalline TiO 2 is responsible for the enhanced performance of this material.
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BIOSENSORS & BIOELECTRONICS
·
2017
·
IF 7.78
Zhiqing Yang,Yi Wang,Dun Zhang
A novel fast, sensitive, and specific multifunctional electrochemical platform has been proposed for simultaneous detection , elimination, and inactivation of pathogenic bacteria for the first time. The platform is constituted with three-dimensional ZnO nanorod arrays (3D-ZnO) decorated with sliver nanoparticles (AgNPs) and functionalized with vancomycin (Van). Based on the specific recognition of Van for Gram-positive bacteria, the fabricated electrochemical platform has presented high detection sensitivity to Staphylococcus aureus with a low detection limit of 330 cfu/mL and adaptable bacterial-elimination efficiency (50%) at low concentrations (1000–2000 cfu/mL). Moreover, the platform has shown high antibacterial activity (99.99%) arising from the synergistic germicidal effect of the composited antibacterial AgNPs and Van units. The current work could provide new strategies to construct advanced platforms for simultaneous detection, elimination, and inactivation of various pathogenic bacteria.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2024
·
IF 2.7
Yang Liu,Linfeng Sheng,Muhammad Abdullah,Xing Shen,Ying He,Juan Liu,Xin Chen
In situ liquid cell electron microscopy technology has high temporal and spatial resolution, enabling real-time observation of physical and chemical processes in liquid environments. However, the common in situ liquid cell scanning electron microscopy (LC-SEM) technology has faced limitations due to the relatively large thickness of the SiNx window, resulting in unsatisfactory resolution, limiting the broad adoption of the LC-SEM technology. This article represents one novel approach of utilizing ultra-thin SiNx windows for LC-SEM observation of the distribution and dynamic changes of gold (Au) nanoparticles/zinc oxide quantum dots (ZnO QDs)/reduced graphene oxide (rGO) ternary composites in liquid. The results demonstrate a single/near-single dispersed distribution of ZnO QDs on the surface of the rGO, with Au nanoparticles and ZnO clusters mainly concentrated on the rGO folds. The composite structure demonstrates relative stability, attributed to electrostatic forces. Using Au nanoparticles and ZnO QDs as hierarchical reference markers, a high LC-SEM image resolution of ~4 nm is obtained, which allows the observation and motion analysis of the Au nanoparticles, rGO nanosheets, as well as ZnO QDs in the liquid cell. Such LC-SEM technology shows good repeatability on the noble-metal/ZnO-QDs/rGO ternary composite samples, with good potential for the future QD composite material researches.
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