JOURNAL OF MATERIALS SCIENCE
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2025
·
IF 3.9
Ren Shike,Wang Yuan,Wang Tengle,He Ge,Yuan Shaojun
The corrosion of magnesium (Mg) alloys is detrimental to marine ships, pipelines, transportation, etc. Although superhydrophobic surfaces can effectively protect against corrosion by maintaining an air gap between the solid structure and corrosive media, their long-term corrosion resistance remains limited due to the intrinsic properties of the base materials. Herein, we developed a novel superhydrophobic composite coating with superior corrosion resistance by spraying a mixture of superhydrophobic particles, hexadecyltrimethoxysilane (HDTMS)-modified ZnO nanosheet-decorated diatomite (ZnO@DME/HDTMS), and epoxy resin (E51) onto the surface of AZ31B Mg alloy. The resulting ZnO@DME/HDTMS composite coating exhibited outstanding stability and retained its superhydrophobicity over a wide temperature range (0–200 °C). Moreover, the coating demonstrated excellent adhesion and mechanical robustness in tape-peeling and friction tests. Compared to coatings without superhydrophobic particles, the ZnO@DME/HDTMS composite coating showed significantly lower corrosion rates and enhanced overall corrosion resistance in a 3.5 wt% NaCl solution, simulating marine environments. This work not only offers a superhydrophobic composite coating for the anticorrosion of Mg alloys in marine environments, but also gives a new strategy for preparing functional coatings via rational design of diatomite with hierarchical structures. Graphical
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BMC Pulmonary Medicine
·
2025
·Vol. 25
·期 1
·1-11
·
IF 2.8
Luo Jun,Liu Min,Ai Wen,Zheng Xiaoling,Han Lu,Huang Kuo,Zhang Changlin,Wang Peng,Fan Jinhong,Li Qianyuan,Luo Chunhua
Background Timely detection of viable Staphylococcus aureus (MSSA)/ methicillin-resistant Staphylococcus aureus (MRSA) and antimicrobial resistance are crucial for the treatment of patients with pulmonary infection. Methods In the current study, we have developed and evaluated the potential clinical applicability of the PMA TaqMan-based real-time PCR (PMA-TaqMan qPCR) assay for detection of viable MSSA/MRSA and antimicrobial susceptibility directly from bronchoalveolar lavage fluid. Results The PMA-TaqMan qPCR assay demonstrated high sensitivity with a detection limit of 800 CFU/mL within 115 min. Furthermore, the assay required only 45 min of antibiotic exposure and completed antimicrobial susceptibility testing within 160 min. Upon detection of 10 spiked bronchoalveolar lavage fluid samples treated by clindamycin after 24 h, the PMA-TaqMan qPCR assay showed better agreement with culture-based methods in detecting viable bacteria. Subsequent antimicrobial susceptibility results of bronchoalveolar lavage fluid samples spiked by 16 MRSA isolates and 11 MSSA isolates based on the current assay, compared with the standard broth microdilution method, showed an overall agreement of 100% (95% confidence intervals [CI]: 80.64 to 100) for MRSA and 90.91% (95% CI: 62.27 to 98.38) for MSSA. Conclusions Our findings demonstrate that the PMA-TaqMan qPCR assay is a highly sensitive and specific method for the direct detection of viable MSSA/MRSA and antimicrobial susceptibility testing from bronchoalveolar lavage fluid.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2025
·
IF 3.8
Gao Hongfan,Zhang Shujing,Li Xin
Biotinylated antibodies are widely used in ELISA. However, their preparation typically requires labor-intensive purification steps to remove the excess biotinylating reagent. Here, we present a novel one-pot, purification-free strategy for preparing biotinylated antibodies, enabling a robust sandwich ELISA platform for the detection of the cardiac troponin I-C complex, a key biomarker for acute myocardial infarction. By introducing glycine (Gly) as a quenching agent to inactivate the residual biotinylating reagent (NHS-biotin esters) during the labeling process, our method eliminates the need for post-labeling purification while effectively reducing nonspecific background. Systematic optimization of labeling conditions yielded an assay with a detection limit of 1.08 pM and a broad linear quantification range from 3.6 pM to 1 nM ( R 2 = 0.99). The platform demonstrated high specificity, with recovery rates ranging from 91.5 to 101.8% and intra-assay variation below 2.9%. Furthermore, successful validation in a serum amyloid A detection model confirmed the generalizability of the Gly-mediated background suppression strategy. This cost-effective, streamlined ELISA workflow offers a powerful tool for rapid and reliable clinical diagnostics, with potential for broad application in biomarker detection. Graphical abstract This schematic contrasts the conventional and novel one-pot strategies for antibody biotinylation in ELISA. The traditional method requires a cumbersome purification step to remove excess biotin-NHS reagent after labeling. In contrast, our one-pot approach introduces a key innovation: an in-solution quenching reaction. The addition of a small molecule (e.g., glycine) efficiently inactivates residual biotin esters, allowing the biotinylated antibody to be used directly in subsequent steps, thereby streamlining the workflow.
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MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 6
·1-9
·
IF 5.479
Han Yangyang,Liu Mingchen,Li Xinting,Liang Peng,Song Yali,Qiao Xiaoqiang
Polyhedral oligomeric silsesquioxane (POSS) was used to modify spherical silica to fabricate core-shell POSS@SiO 2 microspheres. The material was characterized by Fourier transform infrared experiments, scanning electron microscopy, thermogravimetric analysis and elemental analysis. The material was also used as a stationary phase for HPLC separation. The POSS@SiO 2 column exhibits a reverse-phase liquid chromatography (RPLC) retention mechanism. The column efficiency of alkylbenzenes reaches 67,200 plates·m −1 . The POSS@SiO 2 column was also utilized for separation of basic anilines and polycyclic aromatic hydrocarbons. Compared with the commercial C8 column, the POSS@SiO 2 column exhibits enhanced separation selectivity. The column was also used for the separation of synthetic cytokinins 6-benzylaminopurine and 6-furfurylaminopurine in bean sprout after extraction. In addition, the methacrylate groups on the surface of the POSS@SiO 2 microsphere were further functionalized so as to facilitate the fabrication of versatile stationary phases with various separation mechanisms.
Schematic presentation of the two-step fabrication of polyhedral oligomeric silsesquioxane grafted silica-based (POSS@SiO 2 ) core-shell microspheres for use in HPLC.
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Journal of Coatings Technology and Research
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2025
·
IF 2.8
Wei Zeng-Feng,Zhang Yu-Meng,Liu Xue-Lian,Zhang Bi-Yang,Ni Li-Jie,Quan Heng
This study introduces a mussel-inspired superhydrophobic coating designed to enhance the long-term anticorrosion performance of copper in marine environments. Fluorine-free and fluorine-containing superhydrophobic coatings were developed by O 3 -assisted pretreatment, solution polymerization of dopamine, and the Michael addition reaction of dodecyl mercaptan and perfluorooctyl ethyl mercaptan. The ozone pretreatment allows dopamine to form a denser adsorption layer on the copper surface, which improves the long-term stability of the coating. The contact angles of the two coatings are 152.8° and 155.1°, respectively. Both types of superhydrophobic coatings demonstrate good corrosion inhibition performance, particularly the fluorine-containing superhydrophobic coating (99.98%). After 28 days of simulated seawater immersion, the fluorine-containing coating still maintains high corrosion inhibition efficiency (97.02%) and good hydrophobic characteristics (140.7°), which highlight its excellent long-term seawater corrosion resistance and stability. This study provides guidelines for designing durable superhydrophobic coatings.
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IONICS
·
2025
·
IF 2.6
Wang Ying,Liu Wenda,Zhao Huimin,Zhu Yu,Wang Qiqi,Wei Jinli,Javed Maroosha,Zhuang Linghua,Wang Guowei
Two hydroxyl-containing ionic liquids (HCILs) were synthesized and used for dissolving microcrystalline cellulose (MCC). Two HCILs were [MPmim][Cl] (1-methyl-3-(3-hydroxypropyl)-imidazolium chloride) and [MPbim][Cl] (1-butyl-3-(3-hydroxypropyl)-imidazolium chloride). Two hydroxyl-containing ionic liquids were studied with nuclear magnetic resonance ( 1 H NMR and 13 C NMR), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), and elemental analysis. Solvatochromic parameters ( β and π * values) of two HCILs were studied. MCC dissolution performance was evaluated and the regenerated MCC was characterized. Density functional theory (DFT) calculations were employed to gain insights into dissolution mechanism of MCC in [MPmim][Cl] or [MPbim][Cl]. [MPmim][Cl] and MPbim][Cl] demonstrated approximately same β value (0.72, or 0.73), while π * value of [MPmim][Cl] ( π * = 1.11) was slightly higher than that of [MPbim][Cl] ( π * = 1.02). At same temperature, MCC dissolution time in HCILs shortened from butyl group ([MPbim][Cl]) to methyl group ([MPmim][Cl]). DFT calculations revealed that hydroxyl group in [MPmim][Cl] or [MPbim][Cl] formed strong hydrogen bonds with hydroxyl groups of cellobiose. The strong hydrogen bonds were formed between cellobiose and imidazolium cation, as O44-H45…O67 (1.777 Å) and O67-H68…O42 (2.022 Å), which weakened the intermolecular hydrogen bonding network of MCC, thus improving the MCC dissolution process. Characterization of regenerated MCC confirmed that the highly crystalline cellulose transformed into more amorphous form during the ionic liquid dissolution process. The results will shed light on preparation and selection of functional ionic liquids for cellulose dissolution and broaden industrial application of cellulose materials.
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COLLOID AND POLYMER SCIENCE
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2025
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IF 2.3
Zhou Huibin,Wang Hairui,Zhang Hongyu,Chen Liheng,Han Qingzhen,Zong Chengzhong
Polyurethanes are widely used in many fields, and with the expansion of market demand, the improvement of their comprehensive performance through modification techniques has become a research priority. In this paper, modified polyurethane (MPU) was synthesized by reacting terminal hydroxyl polyurethane prepolymer (Pre-PU) with maleic anhydride (MA), and the effects of the introduction of MA as well as the different additions on the properties of MPU were investigated. The structure of MPU was determined using Fourier transform infrared spectroscopy, and the water contact angle and water absorption tests showed that the hydrophilicity of MPU was significantly enhanced, and from the solvent resistance test, it was known that MPU was easy to decompose in acetone, and from the results of the differential scanning calorimeter and the heat loss analyzer, it was known that modified polyurethanes were tunable in terms of their thermal properties by adjusting the amount of MA added. The results of the study offer the possibility of expanding the application areas of polyurethane and its application in special environments.
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Journal of the Korean Ceramic Society
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2024
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IF 2.7
Wang Zikang,Qian Miao,Shao Geyu,Xu Yuzhen,Song Qi
In this study, spark plasma sintering technology was used for fabricating B 4 C composite ceramics that contained 30 wt% (TiB 2 + SiC) by altering the sintering pressures (0 MPa, 50 MPa, and 80 MPa) at a comparatively low temperature of 1650 °C. This study showed how sintering pressure affected the densification behavior, microstructures, and mechanical characteristics of composite ceramics. Elevating the sintering pressure led to the inhibition of grain growth during the sintering process, ultimately resulting in the refinement of grains within the composite ceramics. At the same time, the quantity of internal pores in the composite ceramics was reduced, and the relative densities increased, so the flexural strength and hardness of the composite ceramics could be effectively improved. The quantity of microcracks and large aspect ratio second phase particles decreased with an increase in sintering pressure, which adversely affected the fracture resistance characteristics of the composite ceramics. In addition, the growth of B 4 C grains was hindered by TiB 2 and SiC generated by in-situ reactions, thus improving the mechanical characteristics of the composite ceramics. Comprehensive analysis showed that the composite ceramics had the best comprehensive mechanical properties when the sintering pressure was 80 MPa, displaying a relative density of 98.65%, a Vickers hardness of 30.71 GPa, a flexural strength of 531.19 MPa, and a fracture toughness of 5.78 MPa m 1/2 .
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2025
·Vol. 36
·期 8
·1-10
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IF 2.8
Tu Chuanbin,Xu Guojun,Chen Jun,Jin Chenxin,Gong Haojun,Liu Ji,Sun Fugen,Li Yong,Zhou Lang,Yue Zhihao
In this paper, copper (Cu) nanoparticles is deposited on the surface of silicon (Si) particles by electroless deposition. Then the electrode is prepared by mixing the modified Si/C particles with conductive agents and adhesives. Finally, rapid thermal process (RTP) is used to treat the electrode, so that interfacial Cu–Si alloyed and uniform carbon-coated Si anode materials (Si/Cu 3 Si/Cu@C) are obtained by one step. The reversible specific capacity remains 1362 mAh g −1 after 100 cycles at 0.2 C (1 C = 4.2 A g −1 ), which is 997 mAh g −1 higher than that of Si electrode. Through the multiplier test, the specific capacity of Si/Cu 3 Si/Cu@C holds on 604 mAh g −1 at 2 C. The excellent electrochemical performance of Si/Cu 3 Si/Cu@C composite materials is mainly attributed to the dual buffering media of nano-copper particles and carbon layers. Firstly, the presence of copper particles on the silicon surface can improve the overall conductivity and the volume expansion coefficient of silicon, thereby overcoming the rapid capacity decay of the electrode caused by excessive resistance. Secondly, the surface carbon layer can further alleviate the mechanical stress during the lithium intercalation and deintercalation process, effectively isolate the active material from the current collector, and ensure good electrical contact of the active particles and the stability of the surface SEI film.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 5
·1-9
·
IF 5.3
Li Rui,Que Wenzhong,Han Haiyan,Shi Honghui,Wang Rongfeng,Qiu Bin
IL-17 (interleukin-17) is a common proinflammatory cytokine and can be adopted as an important biomarker for several diseases; it is thus very necessary to design an effective method for monitoring IL-17. Herein, by preparing silver nanoparticles/graphdiyne (Ag/GDY) with simple electroless deposition as the sensing platform and methylene blue/UiO-66-NH 2 MOFs (MB/MOFs) as the signaling-amplifier, a highly efficient sandwich-like electrochemical immunosensing (SLEI) platform was designed for IL-17 detection. The superior electrical property, easy preparation, large surface area, and high stability of Ag/GDY make it a desirable substrate to immobilize primary antibody of IL-17. Meanwhile, the unique structure of UiO-66-NH 2 is beneficial to immobilize MB probe and secondary antibody. By optimizing experimental conditions, the MB current obtained at the as-designed SLEI platform increases along with IL-17 increase, and the related linearity is 1.0 pg mL −1 –1.0 ng mL −1 coupled with a low detection limit of 0.3 pg mL −1 . It is expected that the SLEI platform based on Ag/GDY and MB/MOFs shows some potential application for IL-17 detection. Graphical abstract
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JOURNAL OF MATERIALS SCIENCE
·
2025
·
IF 3.9
Yang Na,Wang Zihan,Liu Ze,Tian Huafeng,Gao Dahai,Guo Gaiping,Dai Yuhua
As a hydrophobic natural protein, zein has attracted extensive attention because of its versatility and excellent biodegradability. However, neat zein exhibits poor spinnability during electrospinning. To fabricate zein-based nanofibers, different hydrophilic co-spinning agents (collagen (Co), gelatin (GE) and polyethylene oxide (PEO)) were incorporated and optimized electrospinning parameter (voltage) for each additive was reported. The relationship between the performance of spinning solution as well as the spinnability and microstructure of zein nanofabrics was analyzed in detail. Co-spinning could improve the spinning ability of zein. The morphology of nanofibers was improved to varying degrees by adjusting the content of co-electrospinning agents and adjusting process parameters. The viscosity, conductivity and the pH value of the spinning solution with different co-spinning agents were analyzed. PEO exhibited a more dramatically effect on improving the spinning ability of zein. The zein-based film had a uniform and complete structure and certain hydrophobicity, and exhibited wide application prospects.
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Journal of Food Measurement and Characterization
·
2025
·
IF 3.3
Jie Mingsha,Zhu Amei,Zhu Bing,Guo Ruipeng,Lan Shengkai,He Jiaxin,Lang Xingang,Bai Yanhong
The overuse of antibiotics leads to significant health risks and environmental challenges. Therefore, selective and sensitive detection of antibiotic residues is a critical issue. Here, a double-emission ratiometric fluorescence probe (Lu-Eu-DPA) was constructed for the selective detection of gentamicin sulfate (GEN), neomycin (NEO), and erythromycin (EM). The Lu-Eu-DPA coordination polymer nanoparticles composed of luminol, the coordinated nuclear metal Eu 3+ , and 2,6-pyridinedicarboxylic acid (DPA). The coordination reaction between luminol molecules and Eu 3+ ions produce the aggregation-induced emission (AIE) effect, while DPA acts as a ligand for the antenna, absorbing energy from the excitation light and then transferring the energy to Eu 3+ . Based on the AIE effect and antenna effect (AE), the fluorescence intensity of Lu-Eu-DPA at 426 nm and 617 nm was correlated with the concentration of GEN, NEO, and EM, and the detection limits of GEN, NEO, and EM were 20, 25, and 48 nmol/L, respectively. The detection capability of the proposed method in pork samples was also studied. In addition, semi-quantitative determination of GEN, NEO, and EM was conveniently and efficiently performed using a smartphone-based visualization method. These results suggested that this probe with good selectivity and specificity was a promising method for swiftly detecting multiple antibiotic residues.
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