ACS Applied Materials & Interfaces
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2025
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IF 8.2
Yuzhi Zhou,Xiao Tang,Lin Xu,Chuan Jing,Yanhong Li,Faling Ling,Hongmei Yang,Shengnan Duan,Xianju Zhou
Electrochromic (EC) technologies offer great prospects of applications in smart windows and nonemissive displays due to their low energy consumption and electrically controlled optical modulation. However, electrolytes, as the essential component of traditional electrochemical EC devices, cause challenges such as limited device design strategies and problems in safety, stability, and integration, hindering the full commercialization of EC devices. Herein, an innovative strategy for designing electrochromic devices is proposed using organic/inorganic semiconductor heterojunctions. The heterojunction is constructed by the C-rich carbon nitride-conjugated polymer (CPCN) with the π* electron accumulation effect and TiO2 nanocrystals with high dielectricity with an architecture of TiO2/CPCN/TiO2 to build interfacial energy barriers or electron transfer routes. These interfacial effects facilitate electron injection, transport, and accumulation, causing changes in the electronic structure of materials and thus their light absorption properties, thereby achieving bistable electrochromism. Using the heterojunction, a nonelectrochemical EC device with the symmetric architecture of FTO/TiO2/CPCN/TiO2/FTO is fabricated, free of electrolytes, enabling an intrinsic all-solid state. The design concept and underlying mechanism are illustrated and substantiated through electrochemical impedance spectroscopy and Mott–Schottky experiments. The electrochromic performances are evaluated through the optical contrast (ΔT), coloration efficiency, response time, and cyclic and long-term stability. The electrochromic display performance based on the laser-etching strategy is particularly investigated.
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ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Shunyu Xiang,Jing Wang,Yang Shen,Xingyi Luo,Xiaoyan Wang,Changyun Liu,Xinyu Chen,Hüseyin Enis Karahan,Jin Huang,Alberto Bianco,Xianchao Sun
Manganese is vital for plant growth and disease resistance but remains underutilized as a bioactive agent due to its toxicity at high concentrations. Here, an effective antiviral nanopesticide system utilizing Mn ions (Mn 2+ ) within safe limits is described. Briefly, cellulose nanocrystals (CNCs) are employed as bio-sourced carrier surfaces and polydopamine (PDA) as a stabilizing and chelating agent for Mn 2+ . By impregnating Mn 2+ onto PDA-coated CNCs, the stable CNC@PDA@Mn 2+ (CPM) composite is fabricated. The CPM composite exhibits a substantially strengthened inhibitory effect on virus infectivity and curtails virus accumulation in Nicotiana benthamiana . The synergistic effects of CPM stem from its ability to directly disrupt viral particles and activate the plant-immunity-related antioxidant systems. Additionally, H 2 O 2 generated by the CPM-activated superoxide dismutase potentially serves as a molecular signal to overexpress the disease-resistance gene harpin-induced 1 ( NbHin1 ) by sulfinylating CCA1 Hiking Expedition and enhance its binding to NbHin1 promoter. Subsequently, this upregulation coordinates the activation of NbHin1 -dependent macroautophagy, triggering multiple antiviral defense mechanisms. Thus, this design achieves highly potent broad-spectrum antiviral activity at low concentrations of manganese (16 µg mL −1 ). Notably, this work pioneers the use of Mn 2+ in triggering plant antiviral defense, offering a solid foundation for designing novel antiviral agents.
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ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Yuhan Fu,Yali Li,Yang Chen,Jidong Hu,Hai Liu,Jiawei Zhao,Shoukun Zhao,Hongyun Ma,Yujun Fu,Deyan He,Junshuai Li
The performance of aqueous zinc-ion batteries is frequently hindered by anode-related issues such as uncontrolled dendrite formation and side reactions. Metal–organic frameworks (MOFs), characterized by their highly ordered porous structures, remarkably large specific surface areas, and tunable active sites, offer a promising solution by regulating Zn2+ flux and promoting uniform Zn deposition. In this study, a Cu-MOF was synthesized in situ on carbon cloth (CM-C) and functioned as an ion-buffering layer within the battery. This innovative configuration significantly mitigates side reactions, achieving an extended cycle life of nearly 800 h at a high current density of 10.0 mA cm–2 (areal capacity: 10.0 mA h cm–2) and nearly 1200 h at 5.0 mA cm–2. After 2000 cycles at 5.0 mA cm–2, the battery demonstrated an average Coulombic efficiency of 99.3%. Additionally, the full battery containing CM-C demonstrated enhanced capacity and stability. This simple and novel structure provides new possibilities for enhancing the cycling stability of zinc-ion batteries.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2025
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IF 7.7
Yue-Yang Zhang,Le-Yu Huang,Huiling Wang,Sixuan Meng,Fei Yang,Shi-Yu Liu
Carboxylesterase 2 (CES2), an extensively expressed serine esterase which widely distributed in various organs and tissues, exerts important roles in maintaining normal physiological function while abnormal expression of CES2 was correlated with many metabolic diseases and cancers. Thus, to develop efficient tool for detection of CES2 activity is of great importance in related clinical diagnosis and research of physiological function of CES2. To date, several enzyme-activated fluorescent probes were developed for CES2 sensing. Among which regulation of CES2 in diseases such as diabetics, colitis, cancers and liver injury could be visualized. However, even though CES2 displayed relatively high expression level in kidney, its regulation in pathological process of kidney injury was rarely studied, and thus related preliminary investigation is in urgent demand. Herein, by rational design and construction of an enzyme-activated fluorescent probe (named as DDXB ) with high catalytic efficacy, sensitivity and specificity toward CES2, down-regulation of CES2 activity in acetaminophen (APAP)-induced liver injury and dextran sulfate sodium (DSS)-induced colitis model was successfully visualized. Most importantly, aberrant up-regulation of CES2 in streptozotocin (STZ), renal ischemia reperfusion (IR) injury (RIRI) and cisplatin (CDDP)-induced kidney injury model was first revealed via DDXB- based fluorescence imaging and further confirmed by immunohistochemistry (IHC) staining. Thus, preliminary evidence for identifying CES2 as potential biomarker of kidney injury were first provided, and the newly developed probe could serve as an efficient tool for related diagnosis or further investigation of CES2 physiological function in more diseases.
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Soft Matter
·
2025
·Vol. 21
·期 8
·1583-1591
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IF 2.8
Bin Qiu,Zhao Chen,Xiaomei Pei,Zhenggang Cui,Binglei Song
Innovation in the molecular design of surfactants holds great potential for developing novel soft materials with unique properties. A surfactant with a long alkyl tail is expected to form giant aggregates with intriguing behavior. However, molecules with a large hydrophobic group often suffer from poor solubility in solutions, inhibiting the aggregation process. Herein, a new aspartame-based bicephalous anionic surfactant, disodium stearoyl-L-aspartyl-phenylalanine (C18-AP-2Na), has been synthesized. C18-AP-2Na showed excellent compatibility with the cationic surfactant cetyltrimethylammonium bromide (CTAB) and resulted in transparent viscoelastic mixed systems over a wide range of molar ratios and concentrations. Moreover, when CTAB and C18-AP-2Na were mixed with an equimolar charge ratio, the viscosity increased consistently from 61 mPa s (0.13 wt%) to an astonishing 14 000 Pa s (13.2 wt%). Cryo-TEM images revealed a network of extensively entangled wormlike micelles with cross-sectional diameters of 4–5 nm and lengths extending up to several micrometers at a C18-AP-2Na/CTAB molar ratio of 5 mM : 10 mM. The presence of long alkyl tails is the origin of wormlike micelle elongation. Different from other conventional anionic surfactants, C18-AP-2Na is distinguished by the amino acid unit near the head group. The extended molecular structure is not linear shaped. C18-AP-2Na is able to combine with CTAB molecules through electrostatic attractions while avoiding the too close contact of the alkyl tails. In this way, the formed ionic pairs remain hydrated in solutions instead of being precipitated. In addition, due to the strong attractions between the head groups of C18-AP-2Na and CTAB, the inorganic ions are ineffective to shield the head group charges. The viscosity of the mixed solutions remained nearly unchanged even with NaCl concentrations of up to 5%, demonstrating significant salt resistance. This work utilizes the advantages of the amino acid and develops stable cationic/anionic mixed solutions with strong viscoelasticity. The excellent compatibility as well as the strong salt resistance make the formulations promising for applications in oil recovery, cosmetic formulations, and the creation of smart materials. The self-assembly principles of surfactants demonstrated here also offer valuable insights for designing new viscoelastic systems and molecular structures.
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ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Xing Lai,Weiye Xu,Yukui Gou,Hongxiang Zhang,Jianying Huang,Weilong Cai,Yuekun Lai
Phytate (PhA) holds considerable promise for constructing molecular sieve membranes due to its high density of long-range electrostatic attractions, customizable charge density, and excellent polymer affinity. Herein, PhA-Fe 3+ complexes constructed by controllable coordination assembly are presented, based on metal-organophosphorus biphasic interfacial coordination reactions, and use the PhA-Fe 3+ complexes to regulate the interfacial polymerization (IP) process to generate polyamide (PA) nanofiltration membranes. The PhA-Fe 3+ complexes impart a high density of long-range electrostatic and short-range hydrogen bonding forces to the amine monomers and provide tunable charge densities through flexible metal-organophosphate coordination. Hydrogen bonding and strong electrostatic interactions spatially enrich the amine monomers and temporally slow down their diffusion into the hexane phase, as demonstrated by molecular simulations, resulting in a PA/PhA-Fe 3+ membrane with increased surface area, enhanced microporosity, lower thickness, higher water density near pores, and nanoscale spotted structures. Those structures are recognized as the key factor in achieving a water permeance of 19.2 L m −2 h −1 bar −1 , alongside a MgCl 2 rejection of 96.7% and a Li + /Mg 2+ selectivity of 24.1 (Mg 2+ /Li + mass ratio = 20), surpassing those of reported nanofiltration membranes. This PhA-Fe 3+ complexes-modulated IP strategy offers fresh perspectives for constructing a highly permeable membrane for lithium extraction from salt lake brines. Graphical Here, PhA-Fe 3+ complexes are synthesized through metal-organophosphorus biphasic interfacial coordination to modulate interfacial polymerization, yielding polyamide nanofiltration membranes. Molecular simulations confirm that hydrogen bonding and electrostatic interactions spatially confine amine monomers while retarding their diffusion into hexane, endowing such ultrathin PA/PhA-Fe 3+ membrane with enhanced microporosity, enlarged surface area, nanoscale spotted morphology, and optimized hydration layer density at the pore interfaces. The optimized membrane exhibits high permeability and stable Li + /Mg 2+ selectivity.
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Advanced Science
·
2025
·
IF 14.1
Na Wen,Yating Jiang,Yunhao Song,Jiachao Yang,Jinlin Long,Ying Wang,Xunbin Yu,Shiyun Lu,Tianhua Zhou,Xueping Huang
Postoperative abdominal adhesions are the most common complication following abdominopelvic surgery, posing a significant burden on patients, clinicians, and society. However, current physical barriers often involve a tradeoff between preventing these adhesions and inhibiting inflammation. Herein, a one-stone-two-birds strategy is presented to address this challenge through an injectable intertwined hydrogel containing sulfobetaine, modified aminocaproic acid (A6ACA), and ZnO nanoparticles (PSA-ZnO hydrogel). This intertwined network is stabilized by multiple intermolecular coordination bonds, including hydrogen bonds and electrostatic interactions—enabling facile injection and resistance to abdominal creep stress. Experimental results demonstrate that PSA-ZnO hydrogel fully reduce the severity of peritoneal adhesions in treated rats at both 7- and 14-days post-surgery, outperforming commercially available hyaluronic acid (HA) gel due to its superior antifouling, antibacterial (> 95% clearance of E. coli and S. aureus ,), hemostatic (55 s), and wound healing properties (IL-6 and TNF-α decreased and VEGF increased). Unlike conventional barriers, PSA-ZnO prevents foreign body formation by inhibiting blood clot organization and pathologic fibrin accumulation at wound sites. This integrated approach offers a clinically translatable solution for complete prevention of postoperative adhesions and inflammation, with the potential to improve patient outcomes and reduce healthcare burdens.
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NEW JOURNAL OF CHEMISTRY
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2025
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IF 2.5
Xunhai Pan,Xiaoyan Lin,Lili Liang,Hailing Xi
Strippable film decontamination is critical for removing radioactive surface contamination during nuclear facility decommissioning and accident response. However, the conventional detergents perform poorly in film formation, freeze easily, and are hard to spray at low temperatures (below 0 °C). In this study, a novel ethyl cellulose-g-polyacrylate (EC-g-PA) detergent was successfully synthesized via benzoyl peroxide (BPO) initiated free-radical polymerization of ethyl cellulose (EC), methyl methacrylate (MMA), butyl acrylate (BA), ethyl methacrylate (EMA), and 2-ethylhexyl acrylate (2-EHA). The synthesized EC-g-PA was characterized by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), gel permeation chromatography (GPC), and thermogravimetric analysis (TGA). The film-forming and rheological properties of EC-g-PA detergents at low temperatures were systematically investigated and the mechanical properties of the EC-g-PA film were tested. Moreover, the decontamination efficiency of the EC-g-PA detergent on various plates within the temperature range from −10 °C to 25 °C was also investigated. The results demonstrate that the EC-g-PA detergent exhibits excellent low-temperature fluidity (below 0 °C) and colloidal stability. Notably, it demonstrates rapid film formation and complete peelability within 12 h under subzero conditions. The contamination decontamination rate (CDR) exceeds 90% on ceramic tiles (CT), glass (G), stainless steel (SS), and marble (M), while achieving 78.30% on concrete (C) at 0 °C. These results demonstrate that the EC-g-PA detergent shows significant potential for application in nuclear facility decommissioning and accident response at low temperatures.
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Bioactive Materials
·
2025
·
IF 20.3
Yinhe Han,Lina Guo,Mingqi Wang,Zhen Cao,Xu Zheng,Xinyu Wang,Lingling Jin,Xiaoqing Wei,Xiuli Wang,Jie Zhao
Interactions among neurons, microglia, and endothelial cells (ECs) —the principal components of the neurovascular unit (NVU)—are vital for maintaining central nervous system (CNS) homeostasis and are implicated in numerous neurological disorders. However, mechanistic insights into their crosstalk remain limited due to the lack of physiologically relevant in vitro models. In this study, we present an improved 3D vascularized tri-culture model that integrates human-induced neural stem cells (hiNSCs), human vascular organoids (hVOs), and microglia within a geometrically engineered silk fibroin scaffold. This platform effectively recapitulates critical features of the native CNS microenvironment, including spatial neurovascular patterning and cell-type-specific interactions. Within this model, hVOs significantly promoted neuronal differentiation of hiNSCs, resulting in extended axonal networks and improved neurovascular alignment. Microglial effects were found to be phenotype-dependent: both resting (M0) and pro-inflammatory (M1) microglia inhibited hiNSCs differentiation and vascular development, with M1 cells exerting the strongest suppressive influence. In contrast, anti-inflammatory (M2) microglia displayed the least inhibitory effect and even modestly supported neurovascular maturation. Mechanistic studies revealed that M2 microglia cooperate with hVOs via the stromal cell-derived factor 1 (SDF-1)/C-X-C chemokine receptor type 4 (CXCR4) signaling axis to promote neuronal differentiation. To our knowledge, this represents the first demonstration of SDF-1/CXCR4-mediated immune-neurovascular interaction within a human tri-culture system. Thereafter, this 3D vascularized co-culture model provides a physiologically relevant in vitro platform to investigate neuroimmune and neurovascular interactions. It holds broad potential for mechanistic studies in neurodevelopment and neurodegeneration, drug evaluation, and the development of regenerative therapies.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-13
·
IF 15.7
Yang Yujie,Wang Jiaqiang,Yang Jie,Tong Lihuan,Cui Xiaodan,Fang Manman,Li Zhen
Organic radical materials have attracted significant attention for their unique photophysical properties and potential applications. Herein, we propose an auto triplet excitons supply system to generate radicals through the photoinduced electron transfer process for practical applications. By manipulating the n-π* transition and p-π conjugation, we achieve enhanced photoactivated phosphorescence coupled with rapid radical generation rates in the methoxy-substituted naphthylamine derivative ( OCH 3 -DNaAPh ) and fluorine-substituted naphthylamine derivative ( F-DNaAPh ), confirming the crucial role of the long-lived excitons supply in generating stable radicals upon UV irradiation. OCH 3 -DNaAPh is thus selected for implementing quantitative monitoring and an automated alarm system for UV radiation, featuring a two-stage risk warning model for excessive UV exposure. Furthermore, it acts as the photoinitiator for the polymerization of methyl methacrylate under UV irradiation, further enhancing phosphorescence emission above 473 K. The study describes a method to generate organic photogenerated radicals in the solid state, broadening their scope of practical applications.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Xingmei Wang,Yibo Sun,Fan Liu,Rongda Zhang,Tianyu Wang,Fei Jia,Guanghui Gao
Hydrogels served as core materials for wearable sensors in recent years, yet their practical application was constrained by water-loss-induced instability, suboptimal mechanical properties, and insufficient functionality in complex scenarios. To overcome these challenges, this study innovatively engineered a Janus fiber scaffold-based composite hydrogel biomimetic skin with a triple humidity-responsive mechanism, achieving substantial breakthroughs in performance optimization and multifunctional integration. HSBS leveraged triple humidity response mechanisms: chitosan-gelatin buffering, Janus scaffolds' unidirectional conduction, and LiCl deliquescence, achieving high hygroscopic sensitivity across 30–90 % RH. Concurrently, the HSBS exhibited wide temperature adaptability from −20 °C to 50 °C, exceptional strain-sensing stability, and mechanical durability, with a water retention rate of 76 % at room temperature and a tensile strength of 3.09 MPa. It could also precisely detect variations in skin temperature and humidity, as well as fluctuations in physiological signals. Endowed with a triple humidity-responsive mechanism as its core advantage, this novel biomimetic skin was poised to significantly expand the application frontier of wearable sensors in domains such as healthcare monitoring and sports science.
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Cyborg and Bionic Systems
·
2025
·
IF 18.1
Yue Li,Lu Yang,Qianbo Yu,Yi Du,Ning Wu,Wentao Xu
C-tactile afferents are low-threshold mechanoreceptors that innervate the hairy skin of mammals, essential for emotional interactions. Replication of such a mechanism could facilitate emotional interactions between humans and embodied intelligence robotic systems. Herein, we demonstrate a monolithic synaptic device that replicates and integrates tactile sensing and neuromorphic processing functions for in-sensor computing. The device is operable by both mechanical and electrical inputs, with the mechanoelectrical operation mechanism stemming from the synergistic effect of dynamic ionic migration and injection. As a proof of concept, the device effectively converts spatiotemporal tactile stimuli into distinct electrical signals, which are subsequently encoded to enable the microcomputer to classify multiple discrete emotional states, such as happiness, calmness, and excitement. This monolithic integrated device, which converges mild tactile perception with neuromorphic processing, with high tactile sensitivity and low-energy consumption, establishes an approach for emotional interaction between intelligent robots and human beings.
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