WATER RESEARCH
·
2024
·
IF 11.4
Mansheng Chen,Panpan Wang,Haicheng Jiang,Jiaying Yan,Shiyi Qiu,Zhilin Zhang,Songlin Wang,Jun Ma
Ultralow-pressurized ultrafiltration membrane process with low energy consumption is promising in surface water purification. However, membrane fouling and low selectivity are significant barriers for the wide application of this process. Herein, an ultrathin zwitterionic hydrogel nanolayer was in-situ grown on polysulfone ultrafiltration membrane surface through interfacially-initiated free radical polymerization. The hydrogel-modified membrane possessed improved biological fouling resistance during the dynamic filtration process (bovine serum albumin, Escherichia coli and Staphylococcus aureus ), comparing with commercial polysulfone membrane. The enhanced biofouling resistance ability of zwitterionic hydrogel nanolayer was derived from the foulant repulsion of hydration shell and the bactericidal effect of quaternary ammonium, according to the results of foulant-membrane interaction energy analyses and antibacterial performances. In surface water treatment, the zwitterionic hydrogel layer inhibited biofouling and resulted in the formation of a loose and thin biofilm. In addition, the hydrogel-modified membrane possessed 22% improvement in dissolved organic carbon (DOC) removal and 134% increasement in stable water flux, compared to commercial polysulfone membrane. The in-situ grown zwitterionic hydrogel nanolayer on membrane surface offers a prospectively alternative for biofouling control in ultralow-pressurized membrane process.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2025
·Vol. 36
·期 3
·e70136
·
IF 3.4
Ping Xie,Jing He,Yangjun Ou
Photothermal therapy is a promising adjunctive treatment technique requiring a nanoplatform with excellent biocompatibility, photothermal stability, and precise targeting capabilities. This study aims to develop such a nanoplatform by synthesizing two new manganese(II)-based coordination polymers. The polymers were created by integrating 1,4-bis(imidazol-1-yl)benzene with the ternary ligand tris( p -carboxyphenyl)phosphane oxide, resulting in the formulas {[Mn 3 (L) 2 (bib) 3 (H 2 O) 7 ]·12H 2 O} n (CP 1 ) and {[Mn(HL)(bib)]·H 2 O} n (CP 2 ). These structures, with large surface areas and porosity, enhance drug loading efficiency. Doxorubicin (DOX) was successfully incorporated into a biocompatible HA/CMCS hydrogel-CP composite (HA/CMCS-CPs@DOX), forming a robust nanotherapeutic platform. Under near-infrared light irradiation, these metal-hydrogel composites effectively induced localized hyperthermia, aiding ocular melanoma treatment. We evaluated the effect of HA/CMCS-CP 2 @DOX on the cell proliferation of the uveal melanoma cell line, and the regulatory effects of the system on lncRNA ARAP1-AS1/miR-149-3p/S100A4 were also explored.
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2024
·
IF 5.4
Tao Jiang,Feikai Zhu,Xintao Gao,Xiaochen Wu,Wenyong Zhu,Chuanlong Guo
Acute kidney injury (AKI) is a common clinical problem with no effective treatment. Excessive folic acid (FA) induced kidney tubular injury is characterized by oxidative stress and inflammation, and is a common model of AKI. The excellent pharmacological activity of naringenin (NAR) makes it a potential agent for treating AKI, but its poor solubility limits its application. This study prepared NAR loaded nanoparticles (FU/PVP-NAR) using fucoidan (FU) and polyvinylpyrrolidone (PVP) as carriers, with a particle size of 23.96 ± 2.77 nm. In vitro studies showed that FU/PVP-NAR inhibited excessive FA induced proliferation inhibition, accumulation of reactive oxygen species (ROS), and disruption of mitochondrial membrane potential (MMP) of HK-2 cells. Further confirmed that FU/PVP-NAR inhibited FA induced DNA damage and Cyclic GMP–AMP synthase (cGAS)-stimulator of interferon genes (STING) activation. In vivo studies showed that excessive FA induced AKI features in mice, such as elevated serum creatinine (SCr) and blood urea nitrogen (BUN) levels, accompanied by pathological damage to kidney tissues. The above AKI characteristics induced by FA were alleviated by FU/PVP-NAR. FU/PVP-NAR also inhibited the decrease in antioxidant enzyme levels in kidney tissues induced by FA. Furthermore, in vivo mechanism studies indicated that FU/PVP-NAR inhibited the release of inflammatory factors by inhibiting DNA damage-cGAS-STING pathway. In summary, this study provided the possibility for FU/PVP-NAR as a potential candidate drug for treating FA induced AKI.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Agronomy-Basel
·
2024
·Vol. 14
·期 6
·1302
·
IF 3.3
Xianghan Cheng,Feifei Liu,Peng Song,Xiaolei Liu,Qin Liu,Taiji Kou
The changes in biomass (including yield), copper (Cu) concentration, and the accumulation of wheat (Triticum aestivum. L) in response to soil Cu pollution under nighttime warming had still not been explored. Hence, this study was carried out, and these variations were analyzed from a physiological perspective. Pot trials were performed at two levels of ambient temperatures (no-warming (NT) and average nighttime warming of 0.28 °C (WT)) and two levels of soil Cu concentrations (control check without Cu application (CK) and 100 mg/kg Cu application (Cu)). Soil was collected from the carbonate cinnamon soil region of central China. The warming effects of the passive nighttime warming system were prominent, and the average increment was 0.28 °C. Antioxidant enzyme activities were promoted by warming (p< 0.05) and Cu. The highest yield was achieved in NT-Cu, mainly attributed to relatively strong root activity and photosynthesis caused by supplemental Cu, but the Cu concentration in its grains was close to the threshold (10 mg/kg) for Cu concentration in foodstuff and could present a potential food safety risk. Though nighttime warming did not increase the total biomass and yield of wheat, it decreased the Cu accumulation of wheat grown in Cu-contaminated soil, especially in grains. Moreover, WT-CK and WT-Cu increased the Cu concentration in the roots and glumes and reduced the Cu concentration in grains by 13.09% and 55.84%, respectively, probably because of a lower transpiration rate. Among them, the Cu concentration of grains in WT-Cu was the lowest and significantly lower than other applications. Our findings reveal that nighttime warming has the potential to reduce the Cu risk of grains in wheat grown in the Cu-contaminated carbonate cinnamon soil region of central China and could then provide a theoretical reference for risk assessment of food quality for wheat subjected to dual stress from nighttime warming and Cu pollution.
✓ 已验证
产品关联
DOI
高影响因子
DESALINATION
·
2024
·
IF 8.3
Jiapeng Wang,Hua-Bin Yuan,Yongxuan Xiang,Lili Xing,Xinpeng Chen,Yifeng Wang,Jiazhuang Chen,Guoqiang Chen,Tieling Xing
Oxygen evolution reaction (OER), as a half-reaction of water decomposition, has a high theoretical overpotential. Therefore, the development of electrocatalysts with high OER performance is favorable for electrolytic hydrogen production. In situ growth of nanomaterials on conductive substrates is an effective strategy for the preparation of electrocatalysts. In this work, we grew Ni/Co bimetallic metal-organic framework (MOF) on carbon cloth substrates and successfully constructed a robust NiCo 2 S 4 /FeS@CC electrocatalyst through a MOF derivatization strategy. This electrocatalyst can be used for efficient and robust OER performance. MOF-derived NiCo 2 S 4 /FeS has the advantage of a porous heterostructure and multicomponent with many active sites and faster charge transfer rate, while sulfur doping greatly improves the OER performance. The current density of this self-supported heterogeneous material in alkaline freshwater reaches up to 10 mA cm −2 with an overpotential of only 238 mV. NiCo 2 S 4 /FeS@CC exhibited good OER performance in alkaline brine with an overpotential of only 241 mV at 10 mA cm −2 . We speculate that this is due to the generation of a negatively charged SO 4 2− anionic layer on the catalyst surface during the electrooxidation process, which effectively avoids Cl − corrosion. And both conditions demonstrate excellent long time stability. Additionally, we succeeded in further reducing the onset potential and energy consumption by adding ethanol or methanol to the electrolyte. This work provides an effective method to improve the OER performance of MOF-derived transition metal electrocatalysts for hydrogen production from electrolytic water.
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2018
·Vol. 42
·期 5
·3851-3856
·
IF 3.201
Shuyun Zhu,Cuihua Lei,Yue Gao,Jing Sun,Hongwei Peng,Han Gao,Ruixue Zhang,Rui Wang,Xian-En Zhao,Hua Wang
Ascorbic acid (AA), as one of the most important neurochemicals in cerebral systems, plays a vital role in many physiological and pathological processes. Herein, a facile, label-free, and ultrasensitive fluorescence sensing system was developed for the determination of AA based on the Ag+–o-phenylenediamine (OPD) interaction. OPD could be oxidized by Ag+ to generate fluorescent 2,3-diaminophenazine (OPDox). When AA was introduced, on the one hand, AA can inhibit the oxidation process due to its strong reducing capability. On the other hand, AA can be oxidized to dehydro-AA with an absorption peak at 380 nm, which has a good spectral overlap with the emission of OPDox. Thus, the inner filter effect (IFE) between dehydro-AA and OPDox may occur. Therefore, the introduction of AA can intensively suppress the fluorescence of the Ag+–OPD system. Benefitting from the remarkable synergistic effect of the reducing capability of AA and IFE, a facile and ultrasensitive sensor was constructed successfully for AA sensing. The whole detection procedure was achieved within 10 min. The linear response range of AA was obtained from 0.05 to 40 μM with a detection limit of 10 nM. This developed method has many merits including more simplicity, good selectivity, excellent biocompatibility, and more cost-effectiveness without using any nanomaterials. Notably, the proposed method was successfully applied to detect AA in rat brain microdialysates in the presence of catecholamines, thus providing a new route for AA detection in physiological and pathological fields.
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL LETTERS
·
2024
·
IF 1.6
Tianhan Zhang,Chengyi Xie,Yong Wu,Wenqing Gao,Chenlu Wang,Keqi Tang,Jiancheng Yu
A compact in-trap single photon ionization (SPI) system, termed discontinuous atmospheric pressure interface (DAPI) ion trap mass spectrometry (ITMS), for the rapid determination of trace volatile organic compounds (VOCs). DAPI enables the maintenance of high analyte pressure in the SPI source while preserving the vacuum. Utilizing vacuum ultraviolet (VUV) lamp as the ion source, we ionize the analyte within an enclosed miniature 3D ion trap for efficient analysis. Experimental findings demonstrate that the system achieves a mass resolution of less than 0.5 atomic mass units for full width at half maxima (FWHM), providing unit resolution. For the response for benzene, the system achieves almost instantaneous response, with rise and fall times of only 2 s, which is a significant advantage compared to the membrane inlet (MI) approach necessary for on-site detection. Additionally, tandem mass spectrometry (MS/MS) with unit m/z isolation window was achieved and resolved dimethyl disulfide and phenol with similar molecular weights. Our results demonstrate that the system provides excellent performance and we anticipate its application in rapidly determining VOCs.
✓ 已验证
产品关联
DOI
高影响因子
WATER RESEARCH
·
2025
·
IF 12.4
Xuan Rui,Huabo Gong,Jinwen Hu,Haiping Yuan,Yawei Wang,Lixia Yang,Nanwen Zhu
Leachate from municipal solid waste (MSW) incineration harbors a plethora of contaminants, including antibiotics and antibiotic resistance genes (ARGs). However, the understanding of such leachate is markedly scant in comparison to that of landfill leachate. In this study, the distribution and removal of 8 sulfonamides (SAs), 4 quinolones (FQs), and 4 macrolides (MLs) antibiotics in leachate from 14 MSW incineration plants in representative cities across different regions of China were investigated. In addition, potential factors affecting the contamination levels of antibiotics and ARGs in fresh leachate were evaluated. The results showed that the total concentration of target antibiotics in fresh leachate ranged from 4406.1 to 14,930.6 ng/L. Notably, the antibiotic distribution in leachate exhibited regional disparities, influenced by economic status, climatic conditions, and waste separation policies. The absolute abundance of total ARGs ranged from 1.3 × 10 7 –4.0 × 10 8 copies/mL, with the mobile genetic elements intl1 facilitates the dissemination of qnrS, sul1 and sul2. No distinct regional distribution of the ARGs was observed among different cities. Antibiotic and ARGs distributions were significantly correlated with total organic carbon, pH, ammonia nitrogen, heavy metals, and microbial communities. Moreover, SAs were identified as contributors to the proliferation and spread of corresponding ARGs. Fourteen typical "anaerobic-anoxic/aerobic-anoxic/aerobic-ultrafiltration-nanofiltration " treatment processes removed the target antibiotics effectively (76.1 %-97.0 %). Biodegradation was considered to be the dominant antibiotic removal pathway, removing 62.0 %-90.9 % of antibiotics, while sludge adsorption removed only 1.0 %-11.7 %. This research furnishes valuable insights into the fate of antibiotics in MSW incineration leachate.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Youming Zuo,Fan Zhu,Shuo Jiang,Zhongquan Sui,Xiangli Kong
The structure of starch often influences its interaction mode and affinity with polyphenols, subsequently impacting the functional properties of starch-polyphenol complexes. This study delved into the multiscale structure, physicochemical properties, and digestive performance of complexes formed by tannic acid (TA) with starches of different polymorphisms (corn starch (CS), potato starch (PS), and pea starch (ES)). The results revealed that TA induced notable changes in the surface morphology and aggregation behavior of starch pastes, with the most pronounced effects observed in ES. Elevated gelatinization enthalpy change and decreased thermal stability were observed in ES-TA complexes, contrary to complexes formed with CS and PS. TA enhanced the crystallinity of three pre-gelatinized starches, facilitating the formation of long-range ordered structures but disrupting short-range ordered structures, with effects more pronounced and TA-concentration-dependent in CS and ES rather than PS. The viscoelasticity of PS gel was strengthened, while that of CS and ES gels was reduced by TA. Digestive outcomes demonstrated that TA increased the resistance to digestion in all three starches, with CS exhibiting the most significant effect, followed by ES and PS. This might be linked to the binding modes of TA with different crystalline starches. The observed variations in regulatory effects on structure and function of starches from different sources combined with TA enhanced our understanding of TA-starch interactions, providing insights into the interaction between polyphenols and starch of different crystalline types.
✓ 已验证
产品关联
DOI
高影响因子
Agronomy-Basel
·
2024
·Vol. 14
·期 8
·1697
·
IF 3.3
Jing Xia,Lili Nan,Kun Wang,Yuheng Yao
Medicago sativais a high-quality legume forage that is widely cultivated around the world. However, low phosphorus (LP) stress is one of the main limiting factors for its yield and quality. Currently, it is unclear how various alfalfa root types respond to LP stress. Thus, the creeping-rootedM. varia‘Gannong No. 4’ (or GN), tap-rootedM. sativa‘Longdong’ (or LD), and rhizomatous-rootedM. sativa‘Qingshui’ (or QS) were selected to detect changes in growth, metabolites, phytohormones, and organic acids after 34 days of LP stress treatment (0.01 mmol·L−1KH2PO4). We observed LP stress significantly inhibited plant growth, and 123, 73, and 42 considerably upregulated differential metabolites were categorized into 33, 26, and 20 metabolic pathways in GN, LD, and QS under LP stress, respectively. Amino acids, plant growth regulators, and organic acids are the main metabolites. After 34 d of LP treatment, the plant height, total surface area, leaf length, ground biomass, leaf width, total volume, leaf area, and ZT content of different root types of alfalfa significantly decreased, while the contents of malic acid, citric acid, oxalic acid, IAA, ABA, and GA3significantly increased. The plant height, leaf length, leaf width, leaf area, total surface area, total volume, ground biomass, root biomass, the number of different metabolites, and the contents of malic, citric, and oxalic acid, and IAA of GN were significantly higher than those of QS and LD under LP stress. From this point of view, GN was more tolerant than LD and QS under the LP condition.
✓ 已验证
产品关联
DOI
高影响因子
POLYMER
·
2024
·
IF 4.1
Zhenxian Chen,Yingying Wang,Zhao Li,Hui Zhang,Ming Wan,Nan Zheng,Bijin Xiong,Jintao Zhu
The cavitation behavior of polypropylene-silica (PP-silica) and high density polyethylene-silica (HDPE-silica) composites with varying silica content during uniaxial tension was investigated via in situ X-ray techniques. The introduction of silica was found to significantly influence the mechanical properties of the materials. Small-angle X-ray scattering (SAXS) was employed to determine the cavitation onset strain and to observe the evolution of cavity structures. Through model fitting, the size evolution of nanoscale cavities at the onset of cavitation was quantitatively characterized. Scanning electron microscopy (SEM) was utilized to examine the morphology before and after stretching, revealing that cavity structures primarily resulted from internal defects in the polymer matrix and interfacial debonding between silica and the polymer. The long axis of the nanoscale cavities at the onset of cavitation was perpendicular to the tensile direction, and further deformation led to the coalescence into micron-sized cavities with the long axis parallel to the tensile direction. Wide-angle X-ray scattering (WAXS) was used to characterize the microscale deformation process of crystals, showing that during stretching, the lamellae reoriented with the angle between their normal direction and the tensile direction gradually decreasing. Several sets of transition strains representing the plastic deformation were used to compare the microscale and macroscale deformation, elucidating the sequence and differentiation between crystal plastic deformation, cavitation, and yield in the two polymer materials. Intriguingly, both PP-silica and HDPE-silica composites exhibited optimal silica additions and initial structural parameters for regulating cavitation behavior. These findings offer significant guidance for the control of internal structures in porous separators in industrial production.
✓ 已验证
产品关联
DOI
高影响因子
Surfaces and Interfaces
·
2025
·
IF 6.3
Xinru Wang,Jiangang Wu,Shumei Xia,Keli Yang,Ran Jia,Xin Liu
Potassium chloride is an important inorganic product widely used in agriculture, chemical industry, medicine, dyes and other fields. In China, quite a part of KCl produced via flotation technique, using hydrochloride octadecylamine (ODA-H) as the flotation agent. The residue of ODA-H will influence product quality or cause different problems, which have gained much attention. However, recent studies focus on the purification techniques based on dissolution-recrystallization process, significantly increasing production cost and causing practical challenges. Herein, a simple but efficient method was presented for the in-situ desorption of ODA-H from the surface of KCl in high salt system. Results revealed that the removal efficiency of ODA-H can be significantly influenced by cations, especially Li + , which the removal efficiency can increase to 60 %. Importantly, the desorption was verified by in-situ Raman spectrum, further proving the exceptional removal rate by Li + rather than the non-dissolution effects. DFT simulated results manifested the function of Li + , which illustrated the large lattice deformation and the strong adsorption effects, not only in acidic condition but also in neutral system. This study will open a new route for the removal of contaminant from the surface of soluble solid in concentrated salt solution.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）