EUROPEAN POLYMER JOURNAL
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2024
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IF 5.8
Guoqing Cui,Chaojie Chen,Yuanlong Li,Li Liu,Guangfeng Wu
The strength and toughness of hydrogel are usually achieved through the synergy of chemical cross-linking and physical cross-linking from multi-component contributions. However, there are few reports on hydrogels that rely on a single component to obtain two cross-linked structures. Herein, we successfully synthesized an amphiphilic macromolecular crosslinker (polyoxyethylene 20 oleyl ether acrylate (O20AC)), and introduced it into a system composed of acrylamide (AAm), sodium chloride (NaCl) and water to prepare the P(AAm-O20AC)/NaCl hydrogel with high strength, outstanding toughness, and excellent good conductivity. Notably, the O20AC possess both crosslinker properties, which not only provide hydrogels with a stable chemical cross-linking network, but also its long hydrophobic chain act as physical crosslinking points to give the hydrogel a new pathway of energy dissipation.Depending on the O20AC crosslinker, the P(AAm-O20AC)/NaCl hydrogels exhibit good strength (tensile stress 714.46 kPa), toughness (elongation at break 3005 %), and fatigue resistance (overlap of hysteresis curves in repeated loading–unloading cycles). Besides, the existence of sodium ions and chloride ions also provides the hydrogel with highly sensitive deformation-dependent conductivity (GF is 5.8 in the 400 %-500 % strain range). Collectively, the strategy of preparing chemical and physical double-crosslinked hydrogels by amphiphilic O20AC will provide a bran-new insights for the development of hydrogel sensing materials.
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CHEMOSPHERE
·
2024
·
IF 8.1
Xian Zhang,Ze Liu,Hafiz Ihsan Ul haq Khan,Diederik P.L. Rousseau,Stijn Van Hulle
This study explored Mason pine-derived hydrochar (MPHC) as an effective adsorbent and persulfate (PS) activator for degrading bisphenol A (BPA). Increasing MPHC dosage from 0.25 to 2.0 g L −1 raised BPA removal from 42% to 87%. Similarly, at the same MPHC dosage range and fixed PS concentration (8 mM), BPA removal by MPHC/PS increased from 66% to 91%. Additionally, at a fixed MPHC dosage (1.0 g L −1 ), higher PS concentrations (2–32 mM) resulted in an overall BPA removal increase from 78% to 99%. The optimal pH for BPA removal by MPHC was at pH 3, while for MPHC/PS was at pH 9. BPA degradation by MPHC was optimal at pH 3, whereas MPHC/PS was at pH 3 and pH 9. Additionally, pH 7 favored BPA adsorption for both MPHC and MPHC/PS. The study also considered the influence of coexisting anions and humic acid (HA). PO 4 3− and NO 3 − influence adsorption on MPHC, but these anions' effect on MPHC/PS is limited. Furthermore, the existence of HA had minimal influence on BPA removal by MPHC/PS. The contributions of different reactive species by MPHC for BPA degradation are as follows: electron-hole (h + ) 2%, singlet oxygen ( 1 O 2 ) 7%, superoxide radicals (O 2 •– ) 13%, electron (e – ) 2%, hydroxyl radical ( • OH) 3%, whereas the remaining 48% removal was the contribution of adsorption. For MPHC/PS, adsorption accounted for 39 %, more reactive species were involved in degradation, and the donations are (h + ) 3%, sulfate radicals (SO 4 •– ) 3%, ( 1 O 2 ) 19%, (O 2 •– ) 15%, (e – ) 2%, and ( • OH) 2%. Additionally, the performance of MPHC remains stable after three operational cycles. The preparation cost of MPHC is 3.01 € kg −1 . These results highlight the potential of MPHC as an environmentally friendly material for activating PS and removing organic pollutants, suggesting its promising application in future environmental remediation efforts.
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Frontiers in Pharmacology
·
2024
·
IF 4.4
Xu Xiaodong,Ding Zhao,Pu Chunlin,Kong Changchang,Chen Shijunyin,Lu Weiling,Zhang Jianfa
Introduction: Overexposure to ultraviolet (UV) light is known to cause damage to the skin, leading to sunburn and photo-aging. Chemical sunscreen products may give rise to health risks including phototoxicity, photosensitivity, and photosensitivity. Natural polysaccharides have attracted considerable interests due to diverse biological activities.Methods: A novel polysaccharide isolated was purified and structurally characterized using chemical methods followed by HPLC, GLC-MS, as well as 1D and 2D NMR spectroscopy. The photoprotective effect of the EPS on UVB-induced damage was assessed in vitro using cultured keratinocytes and in vivo using C57BL/6 mouse models.Results: The average molecular weight of the EPS was 5.48 × 106 Da, composed of glucose, mannose and galactose residues at a ratio of 2:2:1. The repeating units of the EPS were →3)-β-D-Glcp (1→3) [β-D-Galp (1→2)-α-D-Glcp (1→2)]-α-D-Manp (1→3)-α-D-Manp (1→. In cultured keratinocytes, the EPS reduced cytotoxicity and excessive ROS production induced by UVB irradiation. The EPS also exhibits an inhibitory effect on oxidative stress, inflammation, and collagen degradation found in the photodamage in mice. 1H NMR-based metabolomics analysis for skin suggested that the EPS partly reversed the shifts of metabolic profiles of the skin in UVB-exposed mice.Conclusion: The EPS exhibits skin photoprotective effects through regulating oxidative stress both in vivo and in vitro. Our findings highlight that the EPS is a potential candidate in sunscreen formulations for an efficient solution to UVB radiation.
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ACS ES&T Water
·
2024
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IF 4.8
Ze Zhang,Wankui Shao,Qiaoling Xu,Shuying Shen,Huaman Sun,Jiehao Zhan,Beini Gong,Lihua Cui,Zhujian Huang
In this study, an electrochemical system combined with peroxymonosulfate (PMS) and chlorine was developed to enhance the removal efficiency of Microcystis aeruginosa. The almost complete inactivation of algal cells can be achieved in 30 min at a chlorine concentration of 30.0 μM, PMS concentration of 0.75 mM, and current density of 15 mA/cm2. Quenching experiments indicate the involvement of •OH, SO4•–, Cl•, •O2–, and 1O2 in the inactivation of M. aeruginosa, and SO4•– plays a crucial role. Besides the inherent contribution of SO4•– in fortifying the electrolysis/PMS/chlorine system, the ability of the system to control algal proliferation is also bolstered by the SO4•– indirect activation of chlorine species. The alterations in superoxide dismutase, CAT, and malondialdehyde activities substantiate the induction of apoptosis in algal cells. The production of free radicals precipitates a cascade of oxidative impairment within algal cells, which is characterized by marked transformations in cell morphology and structural integrity. Further, microcystin-LR in actual water body also could be effectively removed in the electrolysis/PMS/chlorine system. The findings of this study convincingly establish the electrolysis/PMS/chlorine system as an efficient and environmentally friendly electrochemical application in alga wastewater treatment.
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CHEMICAL ENGINEERING JOURNAL
·
2025
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IF 13.2
Xueping Chen,Hao Li,Kai Yu,Yanan Huang,Jianming Pan
Asymmetric nano-badminton is capable of enhancing the biocompatibility and maturation of immune cells, which in turn enhances its biomedical applications. This approach, in turn, enhanced biomedical applications compared with asymmetric spheres. However, this oriented structure and function of such a targeted product has not been universally explored. Moreover, enhancing the hollow architecture of nano-badminton for multifunctionality applications, such as cargo loading, remains an uncharted territory in this domain. In this work, a facile and continuous synthesis strategy was reported for asymmetric hollow nano-badminton with favorable biocompatibility by hydrolysis-condensation control engineering, which is the mediating via the hydrolysis-condensation kinetics of silane coupling agents. Due to its hydrodynamic morphology and hollow structure, silica nano-badminton has superior biocompatibility, and excellent blood lead capture and removal capacity (as high as 79%), outperforming commercial activated carbon by nearly 45% and making it viable for clinical blood purification. Three independent cell-based assessments consistently showing preserved viability and negligible toxicity validate the clinical safety of silica nano-badminton. This study provides a novel reference for the fabrication of silica hollow nano-badminton for biomedical applications.
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Advanced Energy Materials
·
2024
·Vol. 14
·期 16
·2303912
·
IF 24.4
Peipei Wu,Peng Yang,Zhaoqi Liu,Guangzhao Huang,Xinglin Tao,Siyao Qin,Xuanyi Dong,Li Zheng,Hexing Li,Xiangyu Chen,Zhong Lin Wang
In recent years, liquid–solid triboelectric nanogenerator (LSTENG) has attracted great attention. However, its low average power density and long charging time limit the practical application of this technique. Here, for the first time, a liquid–solid triboelectric nanogenerator combined with external charge-pumping method (ECP-LSTENG) is proposed. Compared to traditional LSTENGs, a charge storage capacitor is added in this ECP-LSTENG to store the output charges from the pumping generator. Then, a charge extraction capacitor is formed by the spreading and shrinking processes of falling droplet, while the charging and discharging process between charge storage and extraction capacitors can generate displacement current output for external circuit. Meanwhile, it is found that a special charged droplets adhesion phenomenon happens at the liquid–solid interface, which seriously hinders the continuous output of ECP-LSTENG. To overcome this limitation, a special coaxial deceleration commutation component is designed to ensure continuous output of the ECP-LSTENG. Finally, the peak power density of a droplet (50 µL) reaches 231.8 W m −2 , surpassing the highest research record to date by 1.43 times. This ECP-LSTENG provides a different approach for the future development of large-scale integrated raindrop generators for efficient raindrop energy harvesting.
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Journal of Physical Chemistry Letters
·
2025
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IF 4.6
Yonggang Chen,Ruihao Xue,Ze Gong,Hongyuan Jiang
Controlling the spatial arrangement of nanodots is pivotal for functional nanomaterials and biointerfaces, and the spontaneous self-assembly of block copolymer micelles has been widely used to fabricate ordered nanostructures. However, achieving tunable disorder remains a fundamental challenge. Here, we demonstrate how successive spin coating dynamically modulates both density and disorder in micellar arrays, revealing an unexpected non-monotonic evolution of structural order. By using the Voronoi tessellation and Alpha shapes filtering algorithm, we found that initial coatings produce hexagonal order (interparticle distance: 126 nm, σd/d̅ = 0.12) and intermediate cycles induce maximal disorder (interparticle distance: 95 nm, σd/d̅ = 0.26), while further deposition partially restores order driven by steric hindrance (interparticle distance: 73 nm, σd/d̅ = 0.20). Our successive spin-coating approach achieves tunable disorder equivalent to conventional polymer-blending methods but without additives, offering a versatile strategy for engineering nanoscale surface patterns with potential applications for biomaterials and optical device design.
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Food Analytical Methods
·
2025
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IF 3
Hu Jianan,Hong Dilong,Zhang Huan,Jiang Yuliang
Tryptophan, an essential amino acid for the human body, plays a crucial role in various physiological processes, including protein synthesis, fatty acid metabolism, enhancing energy levels, and being converted into neurotransmitters to regulate sleep and mood. It is also used in the prevention and treatment of pellagra. However, excessive intake of tryptophan can cause adverse effects, so detecting its concentration is of great significance. In this paper a silicon-based carbon quantum dot (N,Si-CDs) tryptophan probe was prepared. The structure and composition of N,Si-CDs were characterized by TEM, FT-IR, and XPS. Fluorescence studies revealed that N,Si-CDs exhibited high selectivity for tryptophan with minimal interference from other substances. There was a good Linear relationship between the fluorescence intensity of N,Si-CDs and the concentration of tryptophan in the range of 5–25 μM, and the detection Limit was as low as 19 nM. N,Si-CDs were successfully applied to detect tryptophan in complex Matrices such as honey, Yili milk powder, water-soluble vitamin C, sour plum soup, and lemon tea, with recovery rates ranging from 81.3% to 106.4%. Cell experiments demonstrated that N,Si-CDs had low toxicity to T24 cells and could be used for live-cell imaging. This N,Si-CDs shows great potential in fields such as food safety, environmental monitoring, and biomedical research.
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ADVANCED MATERIALS
·
2025
·
IF 26.8
Hao Zheng,Jiangbangrui Chu,Shikang Li,Xun Tang,Shicheng Bi,Kerong Chen,Anwei Zhou,Youwen Yang,Xinghai Ning,Yurui Xu
Elderly patients with hyperlipidemia often exhibit resistance to conventional hypolipidemic treatments, underscoring the need for more effective strategies to address lipid imbalances in this high-risk group. This study introduces LipClean, an aerogel-based apheresis device specifically designed to remove harmful plasma lipids. LipClean is constructed using hydrophilic cellulose fibers, which serve as a supramolecular platform for synthesizing hydrophobic conjugated polymers through a Sonogashira-Hagihara reaction. These conjugated polymers are then cross-linked with the cellulose fibers via phosphorylation, generating an aerogel monolith with an interpenetrating network of hydrophilic fibers and hydrophobic polymers. Unlike bilayer aerogels that separate hydrophilic and hydrophobic layers, LipClean's interpenetrating structure is precisely engineered through polymer design and gradient cross-linking. This optimization enhances both bodily fluid flow and lipid adsorption while minimizing the removal of essential plasma components and ensuring unobstructed cell passage. In preclinical testing, LipClean significantly reduced triglyceride and cholesterol levels in an elderly rat model of hyperlipidemia and normalized lipid levels in blood samples from hypertensive patients. Importantly, purified blood maintained normal levels of blood cells and physiological and biochemical indicators after apheresis, highlighting LipClean's potential for managing hyperlipidemia-related disorders. This study, therefore, underscores the importance of interdisciplinary collaboration in driving medical device innovation.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2024
·Vol. 34
·期 39
·2403061
·
IF 18.5
Zhi-Wei Zeng,Bo Tang,Fu-Rong Zeng,Hao Chen,Shi-Qiang Chen,Bo-Wen Liu,Yu-Zhong Wang,Hai-Bo Zhao
Passive radiative cooling is a zero-energy technology vital for mitigating the energy crisis. However, achieving intelligent thermal management across varying weather conditions (day/night and summer/winter) while maintaining sustainability is a significant challenge. Here, a recyclable biomass film engineered for adaptive, year-round energy conservation is introduced. This film utilizes porous acetyl cellulose (AC) as a cooling-side matrix, enabling efficient radiative cooling during hot days (8.5 °C reduction) and minimizing overcooling on cold nights (only 2.5 °C reduction). This performance is facilitated by high solar reflectance (96.3%) and broad-spectrum infrared emission (95.4%), optimizing atmospheric thermal regulation. The reverse side, coated with carbon black (CB), demonstrates superior solar heating (20.9 °C increase), allowing for effortless switching between cooling and heating by flipping the film. Further, the film employs a solvent-responsive ethyl cellulose (EC) adhesion, ensuring durability, complete recycling, and reuse. With ultraviolet (UV) resistance, self-cleaning, and durability, coupled with intelligent thermal management, this work provides new ideas for advanced radiative heat management materials, enabling adaptive control during both daytime/nighttime and summer/winter.
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Cyborg and Bionic Systems
·
2025
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IF 18.1
Yue Li,Lu Yang,Qianbo Yu,Yi Du,Ning Wu,Wentao Xu
C-tactile afferents are low-threshold mechanoreceptors that innervate the hairy skin of mammals, essential for emotional interactions. Replication of such a mechanism could facilitate emotional interactions between humans and embodied intelligence robotic systems. Herein, we demonstrate a monolithic synaptic device that replicates and integrates tactile sensing and neuromorphic processing functions for in-sensor computing. The device is operable by both mechanical and electrical inputs, with the mechanoelectrical operation mechanism stemming from the synergistic effect of dynamic ionic migration and injection. As a proof of concept, the device effectively converts spatiotemporal tactile stimuli into distinct electrical signals, which are subsequently encoded to enable the microcomputer to classify multiple discrete emotional states, such as happiness, calmness, and excitement. This monolithic integrated device, which converges mild tactile perception with neuromorphic processing, with high tactile sensitivity and low-energy consumption, establishes an approach for emotional interaction between intelligent robots and human beings.
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Cell Host & Microbe
·
2025
·
IF 18.7
Jing Yu,Yuxuan Liang,Qingrong Zhang,Hui Ding,Minghao Xie,Jingjing Zhang,Wenyan Hu,Sihua Xu,Yiyuan Xiao,Sha Xu,Rong Na,Baixing Wu,Jiaming Zhou,Haitao Chen
Intratumoral microbiota plays a crucial role in cancer progression. However, the relationship between host genetics and intratumoral microbiota, as well as their interaction in colorectal cancer (CRC) progression, remains unclear. With 748 Chinese CRC patients enrolled from three cohorts, we find that the single nucleotide polymorphism (SNP) rs2355016, located in the intron of ATP-sensitive inward rectifier potassium channel 11 ( KCNJ11 ), is significantly associated with the abundance of Fusobacterium . Compared with the rs2355016 GG genotype, patients carrying the A allele exhibit downregulation of KCNJ11 and enrichment of Fusobacterium , which corresponds to accelerated proliferation and progression. Low expression of KCNJ11 can increase the level of galactose-N-acetyl-d-galactosamine (Gal-GalNAc) on the surface of CRC cells, thereby facilitating the binding of the Fap2 protein from F. nucleatum to Gal-GalNAc. This further enhances the adhesion and invasion of F. nucleatum and promotes CRC growth. Our study explores the interaction between intratumoral microbiota and SNPs in CRC patients, which will enhance our understanding of CRC proliferation.
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