TALANTA
·
2021
·
IF 6.057
Yuanyuan Yao,Hongding Zhang,Tongtong Tian,Yixin Liu,Rendan Zhu,Ji Ji,Baohong Liu
With the emergence of microRNA (miRNA) as a key player in early clinical disease diagnosis, development of rapidly sensitive and quantitative miRNA detection methods are imperative. Herein, a label-free SERS assay coupled with duplex-specific nuclease (DSN) signal amplification strategy was proposed for facilely ultrasensitive and quantitative analysis of miRNA-21. Firstly, magnetic beads assembled with excessive capture DNA were utilized to hybridize the target miRNA-21. These DNA-RNA heteroduplexes were cleaved by DSN to generate small nucleotide fragments into the supernatant and the miRNA-21 released and rehybridized another DNA, going to the next DSN cycle. Consequently, numerous of small nucleotide fragments of capture DNA were released from magnetic beads and the miRNA-21 signal was transferred and amplified by the SERS signals of total phosphate backbones which are abundant in nucleotide. Furthermore, iodide-modified Ag nanoparticles (AgINPs) was employed to generate a strong and reproducible SERS signal. The proposed method displayed excellent performance for miRNA-21 detection with the linear range from 0.33 fM to 3.3 pM, and a lower detection limit of 42 aM. Moreover, this strategy exhibited effectively base discrimination capability and was successfully applied for monitoring the expression levels of miRNA-21 in different cancer cell lines and human serum.
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Ping Wei,Shiheng Yin,Tao Zhou,Chao Peng,Xiaolong Xu,Juncai Lu,Minchao Liu,Jianbo Jia,Kun Zhang
The occurrence of pharmaceutical and personal care products (PPCPs) in the ambient environment has raised serious concerns. Herein, a dispersed ZnFe 2 O 4 nanoparticle loaded Ag@Ag 2 CO 3 nanorod hybrid (ZnFe 2 O 4 /Ag@Ag 2 CO 3 ) was facile prepared, and used as a solar light driven photocatalyst for the degradation of tetracycline (TC), a typical PPCPs. The hybrids were characterized by XRD, SEM, EDS, HRTEM, DRS, PL, TRPL, M−H , BET, XPS, ESR and photoelectrochemical testing. The ZnFe 2 O 4 was evenly dispersed on the surface of Ag@Ag 2 CO 3 nanorods of which diameter was about 100 nm. The obtained ZnFe 2 O 4 /Ag@Ag 2 CO 3 composites exhibited high TC degradation efficiency after 150 min Xe light illumination, which was much better than those of pure Ag@Ag 2 CO 3 and ZnFe 2 O 4 . The photodegradation reaction rate constant ( k ) of the optimum ternary photocatalyst (ZnFe 2 O 4 loading 5% wt) increased 4.04 times and 2.48 times than those of pure ZnFe 2 O 4 and Ag 2 CO 3 @Ag, respectively. More importantly, the stability and recovery capacity of the ZnFe 2 O 4 /Ag@Ag 2 CO 3 photocatalyst improved obviously than those of Ag@Ag 2 CO 3 . The reactive oxygen species (ROS) experiment indicated that • OH、h + and • O 2 − involved in the photocatalytic reaction process, and the ROS contributes order was • O 2 − > h + > • OH. The band positions of individual ZnFe 2 O 4 and Ag 2 CO 3 were elucidated via DRUV–Vis spectra and Mott-Schottky plots. Based on the results of ROS experiment and band structure of ZnFe 2 O 4 and Ag 2 CO 3 , it could be inferred that the photocatalytic reaction of ZnFe 2 O 4 /Ag@Ag 2 CO 3 abided by Z-scheme mechanism, that is, Ag acted as the electronic bridge between Ag 2 CO 3 and ZnFe 2 O 4 , and the • OH and • O 2 − were formed on the valence band (VB) of Ag 2 CO 3 and conduction band (CB) of ZnFe 2 O 4 , respectively, and then TC was further oxidized. The sufficient photocatalytic degradation of TC in ambient water revealed that a sunlight-driven ZnFe 2 O 4 /Ag@Ag 2 CO 3 photocatalytic process may be efficiently applied for the remediation of PPCPs contaminated natural waters.
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APPLIED OPTICS
·
2021
·Vol. 60
·期 22
·6659-6664
·
IF 1.98
Pingping Teng,Danheng Gao,Xinghua Yang,Meng Luo,Depeng Kong,Shuai Gao,Zhihai Liu,Zhanao Li,Xingyue Wen,Libo Yuan,Libo Yuan,Kang Li,Mark Bowkett,Nigel Copner
In this paper, we present a microstructured optofluidic in-fiber Raman sensor for the detection of quinolone antibiotic residue in a water environment based on Ag surface-enhanced Raman scattering (SERS) substrate grown on the surface of the suspended core of micro-hollow optical fiber (MHF). Here, MHF has a special structure with a suspended core and a microchannel inside, which can become a natural in-fiber optofluidic device. Meanwhile, the self-assembled Ag SERS substrate can be grown on the suspended core’s surface through chemical bonds, forming a microstructured optofluidic device with a Raman enhancement effect. Therefore, it can effectively detect the Raman signal of unlabeled trace quinolone antibiotic residue (ciprofloxacin and norfloxacin) inside the optical fiber. The results show that the ciprofloxacin and norfloxacin detection limits (LOD) are ${{10}^{- 10}}\;{\rm{M}}$ and ${{10}^{- 11}}\;{\rm{M}}$, respectively. Compared with the maximum residue limit (${3.01} \times {{10}^{- 7}}\;{\rm{mol}}/{\rm{L}}$) stipulated by the European Union, the results are much lower, and an ideal quantitative relationship can be obtained within the detection range. Significantly, this study provides an in-fiber microstructured optofluidic Raman sensor for the label-free detection of quinolone antibiotic residue, which will have good development prospects in the field of antibiotic water pollution environmental detection.
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Nano Research
·
2021
·Vol. 14
·期 7
·2363-2371
·
IF 8.897
Lv Yan,Yue Lin,Khan Imran Mahmood,Zhou You,Cao Wenbo,Niazi Sobia,Wang Zhouping
Herein, we report the fabrication of Fe 3 O 4 @TiO 2 nanosheet/Ag/g-C 3 N 4 (Fe 3 O 4 @ns-TiO 2 /Ag/g-C 3 N 4 ) composite photocatalysts with well-designed hierarchical yolk-shell structure. To endow the composites with fascinating features, multiple functional components are perfectly integrated into the definite structure. The photodegradation experiments of organic pollutants revealed a significant enhancement in photocatalytic activity of developed composites as compared to P25, which is mainly due to the synergetic interaction of the tailored three-dimensional (3D) yolk-shell porous nanostructure, extended sunlight response range, and retarded the recombination probability of photogenerated electrons-holes. More importantly, the hybrid samples exhibited superior magnetic properties due to the magnetic component. The excellent magnetic recyclability and reusability of the photocatalysts are verified by the magnetic hysteresis loop and cyclic photocatalytic degradation experiments, which is significant for the green and sustainable applications of photocatalysts. Considering its remarkable photocatalytic performance and expectant magnetic recyclability, the composite photocatalysts are expected to be a promising candidate to dispose of future environmental issues.
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SOLAR ENERGY
·
2021
·
IF 5.742
Junye Tong,Shaotong Wang,Gang Wang,Yue Liu,Yuxiang Wang,Liping Chen,Lingling Wang,Daocheng Pan,Xintong Zhang,Yichun Liu
Ion doping strategy is a promising method to enhance the efficiency of Cu 2 ZnSn(S,Se) 4 (CZTSSe) solar cells, however, most of the reported works focus on studying the single ion doping in CZTSSe absorber layers . Here, Li + &Ag + and Li + &Cd 2+ double-ion-doping strategy are applied to improve the microstructure and device performances. We found that the double-ion-doping strategy can obviously increase the grain size, reduce the thickness of fine-grain layers and enhance the device performances. Furthermore, the PCEs of Li + &Ag + and Li + &Cd 2+ doped CZTSSe solar cells are up to 8.87% and 8.39%, respectively. It shows an encouraging improvement of over 43.5% and 35.8% enhancement compared with the traditional method (6.18%), and significantly higher than single ion doping strategy (7.60%, 7.99% and 7.11% for Li + , Ag + , and Cd 2+ doped CZTSSe solar cells). This work provides a new solution to improve the microstructure and device performances of CZTSSe solar cells.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Yue Hu,Weihua Yu,Yunwen Liao,Xiaohui Jiang,Zhengjun Cheng
A stable, water-soluble, heightened quantum yields (QYs) Au nanoclusters by the alliance between doping Ag and dual ligands (thiosalicylic acid and bovine serum albumin) (TSA/BSA-Au/AgNCs) was prepared using one-step wet chemical synthesis. The effect of different types of aromatic thiols and the molar ratio of Au-Ag on the photo-luminescence performance of AuNCs was discussed in detail. The alloy NCs is shown to be viable fluorescent method for vitamin B12 (VB12) and chlortetracycline hydrochloride (CCH) assays, and become an excellent temperature sensor in the range of 10–50 °C. The fluorescence (FL) of TSA/BSA-Au/AgNCs was quenched with the addition of VB12 or CCH coming from Förster resonance energy transfer (FRET) combined with inner filter effect (IFE). The method can detect VB12/CCH by fluorometry with a linear response in the range of 0.33–60.0/0.33–60.0 μmol·L −1 and a 71.0/64.0 nmol·L −1 detection limit (at 3σ/slope). Furthermore, the proposed method was extended to the assays of VB12 in mineral water or tablets and CCH in veterinary drug or ointment with satisfactory results.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Na Chang,Yan-Ru Chen,Feng Xie,Ya-Pan Liu,Hai-Tao Wang
It is of great importance to fabricate photocatalyst with high photocatalytic activity, and the formation of Z-scheme heterojunction photocatalyst has been proved to be an effective way to restrain the recombination of photo-induced carriers. In this work, Z-scheme AgCl/Ag-doped-ZIF-8 heterojunction is synthesized via a two-step process involving appropriate amount of cationic Ag ion doping into the imidazole ring of ZIF-8 framework and the precipitation of AgCl onto this Ag-doped-ZIF-8. The successful doping of ZIF-8 which decreases the band gap energy, enhances the light harvesting. Besides, the separation efficiency of photo-induced carriers is further improved due to the formation of Z-scheme AgCl/Ag-doped-ZIF-8 heterojunction, which is confirmed by photoelectrochemical experiments. As a result, the as-prepared AgCl/Ag-doped-ZIF-8 photocatalyst possesses excellent photocatalytic activity under visible light illumination. This work will provide a novel perspective for the design and construction of Z-scheme heterojunction for highly efficient photocatalysis.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2020
·
IF 2.369
Luxia Yin,Bo Zhang,Jinbing Zhou,Jiacheng Xu,Wanghui Gong,Jianguang Gao,Wensheng Ning,Zekai Zhang,Wei Hua Yu
Ag2O/SiO2–TiO2-n aerogel composites with different molar ratios of Si/Ti, prepared by a sol–gel method followed by the ambient pressure drying technique, were used for the adsorptive removal of thiophenic compounds from model fuels, along with Ag2O/SiO2-50. The physicochemical properties of aerogel composites were characterized by X-ray diffraction (XRD), X-ray fluorescence (XRF) spectroscopy, Brunauer–Emmett–Teller (BET) method, Fourier transform infrared (FT-IR) spectroscopy, NH3 temperature-programmed desorption (TPD), and pyridine (Py) FT-IR spectroscopy. The results indicated that doping Ti into Ag2O/SiO2-50 led to a slight decrease in the specific surface area, an obvious increase in the actual content of Ag, and the appearance of weak Lewis acid centers on the surface. The data for equilibrium adsorption of thiophene over Ag2O/SiO2-50 and Ag2O/SiO2–TiO2-50 were well fitted to the Langmuir and Freundlich isotherm equations. The kinetic experimental data of Ag2O/SiO2–TiO2-50 was well fitted by a pseudo-second-order model. For two adsorbents, negative values of ΔG indicated that the adsorption processes were spontaneous. The adsorption process on Ag2O/SiO2–TiO2-50 was more favorable at higher temperatures, which was contrary to that on Ag2O/SiO2-50. The incorporation of Ti into Ag2O/SiO2-50 can improve the adsorptive desulfurization performance owing to the increase in the actual content of Ag species (π-complexation centers), and thiophenic compounds can be adsorbed via Lewis acid–base interaction and S–Ti binding besides π-complexation. Among Ag2O/SiO2–TiO2-n, Ag2O/SiO2–TiO2-50 performed the best.
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JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Gongduan Fan,Rongsheng Ning,Zhongsen Yan,Jing Luo,Banghao Du,Jiajun Zhan,Lingshan Liu,Jin Zhang
Antibiotic contamination is increasing scrutinized recently. In this work, the Ag−AgCl/WO 3 /g-C 3 N 4 (AWC) nanocomposites were successfully synthesized using a two-step process involving electrostatic self-assembly and in-situ deposition for trimethoprim (TMP) degradation. The as-prepared photocatalysts were investigated and characterized by XRD, FTIR, XPS, TGA, SEM, TEM , UV–vis, PL and EIS. The experimental results indicated that 99.9% of TMP (4 mg/L) was degraded within 60 min when the concentration of AWC was 0.5 g/L. Reactive species scavenging experiments and electron spin resonance (ESR) experiments illustrated that superoxide radical (•O 2 − ) and photogenerated holes (h + ) were the main active species. The functional theory calculation and identification of intermediates via HPLC-MS revealed the possible degradation pathways of TMP. A double photoelectron-transfer mechanism in AWC photocatalyst was proposed. Five cycling photocatalytic tests and reactions under different solution matrix effects further supported that the AWC was a promising photocatalyst for the removal of TMP from the aquatic environment.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Ziwei Hu,Xia Zhou,Jun Duan,Xueqiang Wu,Jiamin Wu,Pengcheng Zhang,Wanzhen Liang,Jialiang Guo,Huaihong Cai,Pinghua Sun,Haibo Zhou,Zhengjin Jiang
The design of a rapid, simple, and ultrasensitive detection platform of protein biomarkers has become an urgent need in early diagnosis and treatment. Surface-enhanced Raman scattering (SERS) technology, with the unique advantages of ultra-sensitivity and fingerprint recognition, has attracted much attention in biomarker detection. An innovative aptamer SERS biosensor for highly sensitive protein biomarker detection was presented. This biosensor contains a SERS tag (reporter-labeled Au nano-bridged nanogaps particles, Au NNPs) and novel magnetic capture substrate (Ag-coated Fe 3 O 4 -Au NPs, Ag MNPs). C-reactive protein (CRP), a representative biomarker for diagnosing, was used to assess the SERS performance of this biosensor. Aptamers against CRP were modified on both SERS tag and magnetic capture substrate for specific recognition by Au NNPs-CRP-Ag MNPs sandwich assay. This strategy achieved sensitive detection of CRP with a limit of detection (LOD) of 10 fM (1.14 pg/mL), and is much lower than reported analytical methods. Besides, this method exhibits excellent selectivity and specificity for CRP under the interference of other proteins and displays high accuracy in the detection of actual human serum samples. This proposed detection strategy can be extended to the sensitive detection of other biomarker proteins and hold great promise in the clinical diagnosis of diseases.
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JOURNAL OF RARE EARTHS
·
2021
·
IF 3.712
Jingzhi Dou,Bei Chen,Guixia Liu,Xiangting Dong,Wensheng Yu,Jinxian Wang,Yunxiao Zhang,Zhanguo Li,Jiang Zhu
Photothermal therapy (PTT) has presented its inherent application value in cancer treatment. Nevertheless, single-functional photothermal materials cannot meet the precise diagnosis and treatment of cancer. Therefore, it is important to design a nanocomposite that has both high therapeutic efficiency and multimodal imaging capabilities. In our work, a new nanostructure of gold nanorods (AuNRs) with silver shells decorated by BaGdF 5 :Yb 3+ ,Er 3+ nanoparticle was synthesized by a simple way. The biostability of AuNRs is increased by coating with silver shells, and the AuNR@Ag nanoparticles can be used as excellent surface enhanced Raman scattering (SERS) probe. Moreover, the modification of BaGdF 5 :Yb 3+ ,Er 3+ nanoparticles provides the possibility of real-time optical imaging of the tumor area. Under the irradiation of NIR laser, the AuNR@Ag/BaGdF 5 :Yb 3+ ,Er 3+ nanocomposites (NCs) have strong upconversion emission and excellent photothermal conversion efficiency. Meanwhile, the NCs show low cytotoxicity and good biocompatibility in MTT cytotoxicity test. Moreover, the NCs are also exceptional contrast agents for CT imaging. For in vitro photothermal therapy test, NCs show excellent killing efficiency on tumor cells. Therefore, the multifaceted research of AuNR@Ag/BaGdF 5 :Yb 3+ ,Er 3+ multifunctional nanomaterials provides a break for high-efficiency tumor photothermal therapy and multimodal imaging.
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JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Gongduan Fan,Zhong Chen,Zhongsen Yan,Banghao Du,Heliang Pang,Dingsheng Tang,Jing Luo,Jiuyang Lin
A novel plasmonic Ag/AgCl@LaFeO 3 (ALFO) photocatalyst was successfully synthesized by a simple in-situ synthesis method with enhanced photocatalytic activity under visible light for harmful algal blooms (HABs) control. The structure, morphology, chemical states, optical and electrochemical properties of the photocatalyst were systematically investigated using a series of characterization methods. Compared with pure LaFeO 3 and Ag/AgCl, ALFO-20% owned a higher light absorption capacity and lower electron–hole recombined rate. Therefore, ALFO-20% had higher photocatalytic activity with a near 100% removal rate of chlorophyll a within 150 min, whose kinetic constant was 15.36 and 9.61 times faster than those of LaFeO 3 and Ag/AgCl. In addition, the changes of zeta potential , cell membrane permeability, cell morphology, organic matter, total soluble protein, photosynthetic system and antioxidant enzyme system in Microcystis aeruginosa ( M. aeruginosa ) were studied to explore the mechanism of M. aeruginosa photocatalytic inactivation. The results showed that ALFO-20% could change the permeability and morphology of the algae cell membrane, as well as destroy the photosynthesis system and antioxidant system of M. aeruginosa . What’s more, ALFO could further degrade the organic matters flowed out after algae rupture and die, reducing the secondary pollution and avoiding the recurrence of HABs. Finally, the species of reactive oxygen species (ROS) (mainly •O 2 - and •OH) produced by ALFO were determined through quenching experiments, and a possible photocatalytic mechanism was proposed. Overall, ALFO can efficiently remove the harmful algae under the visible light, providing a promising method for controlling HABs.
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