Antioxidants
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2022
·Vol. 11
·期 12
·2406
·
IF 7.675
Xiang-Rong Cheng,Bu-Tao Yu,Jie Song,Jia-Hui Ma,Yu-Yao Chen,Chen-Xi Zhang,Piao-Han Tu,Mitchell N. Muskat,Ze-Gang Zhu
Food-derived electrophilic compounds (FECs) are small molecules with electrophilic groups with potential cytoprotective effects. This study investigated the differential effects of six prevalent FECs on colitis in dextran sodium sulfate (DSS)-induced mice and the underlying relationship with molecular characteristics. Fumaric acid (FMA), isoliquiritigenin (ISO), cinnamaldehyde (CA), ferulic acid (FA), sulforaphane (SFN), and chlorogenic acid (CGA) exhibited varying improvements in colitis on clinical signs, colonic histopathology, inflammatory and oxidative indicators, and Nrf2 pathway in a sequence of SFN, ISO > FA, CA > FMA, CGA. Representative molecular characteristics of the “penetration-affinity–covalent binding” procedure, logPvalue, Keap1 affinity energy, and electrophilic index of FECs were theoretically calculated, among which logPvalue revealed a strong correlation with colitis improvements, which was related to the expression of Nrf2 and its downstream proteins. Above all, SFN and ISO possessed high logPvalues and effectively improving DSS-induced colitis by activating the Keap1–Nrf2 pathway to alleviate oxidative stress and inflammatory responses.Keywords:electrophilic compound;colitis;molecular characteristic;logP
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SEPARATION AND PURIFICATION TECHNOLOGY
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2022
·
IF 9.136
Jingyu Ren,Zhouzhou Yao,Qian Wei,Ruotong Wang,Yuan Liu,Long Wang,Kaibin Zheng,Shuai Wang,He Guo,Zhirui Niu,Jian Wang,Jin Han,Lei Lü,Yanzhong Zhen,Jie Li
Organic pollutants of olive mill wastewater (OMW) have caused various negative effect to water environments. It is imperative to develop an effective technology for eliminating organic pollutants in OMW. In this study, representative organic pollutants in OWM, ferulic acid (FA) and caffeic acid (CA), were removed from water by dielectric barrier discharge (DBD) plasma and Mn/CoOOH/activated carbon fiber (ACF) catalyst. The treatment performance and catalytic mechanisms were studied. The results show that the combined system could effectively remove FA and CA. For example, FA and CA degradation efficiency was 81.6% and 94.2% in the 20 L of mixed wastewater with the 100 min treatment using DBD combined with Mn/CoOOH/ACF. Experiments and density functional theory (DFT) calculations indicate that the electron transfer from the catalyst to antibonding orbits of O 3 and H 2 O 2 caused the dissociated adsorption, promoting the transformation of O 3 and H 2 O 2 to ·O, singlet oxygen and ·OH. Additionally, the doping of Mn in CoOOH benefited the electron transfer because Mn had a higher d-band center than Co in Mn/CoOOH, which was conducive to the interaction of O 3 and H 2 O 2 with the catalyst. The possible degradation pathways of FA and CA were proposed.
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ACS Omega
·
2023
·
IF 4.1
Hao-wen Jiang,Yu Qin,Yi-ming Nie,Zhi-fang Su,Yun-fei Long,Yanxuan Wen,Jing Su
The strategy of material modification for improving the stability of silicon electrodes is laborious and costly, while the conventional binders cannot withstand the repeated massive volume variability of silicon-based materials. Hence, there is a demand to settle the silicon-based materials’ problems with green and straightforward solutions. This paper presents a high-performance silicon anode with a binder obtained by in situ thermal cross-linking of citric acid (CA) and β-cyclodextrin (β-CD) during the electrode preparation process. The Si electrode with a binder synthesized by the one-pot method shows excellent cycling performance. It maintains a specific capacity of 1696 mAh·g–1 after 200 cycles at a high current of 0.5 C. Furthermore, the carbonylation of β-CD to carbonyl-β-CD (c-β-CD) introduced better water solubility, and the c-β-CD can generate multidimensional connections with CA and Si, which significantly enhances the specific capacity to 1941 mAh·g–1 at 0.5 C. The results demonstrate that the prepared integrated electrode facilitates the formation of a stable and controllable solid electrolyte interface layer of Si and accommodates Si’s repeated giant volume variations.
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ACS Applied Nano Materials
·
2023
·
IF 5.9
Yun Zhao,Bingli Gu,Guoqiang Guo,Yanshuang Li,Tingting Li,Yuejin Zhu,Xu Wang,Da Chen
The development of multicolor tunable emission graphene quantum dots (GQDs) is important for their application in photoelectric devices and multicolor anticounterfeiting. Herein, we synthesize blue (B-GQDs), green (G-GQDs), and red GQDs (R-GQDs) via a solvothermal reaction. The B-, G-, and R-GQDs exhibit excitation-independent behavior, excellent fluorescence properties, and exceptional photostability. The relative quantum yields (QYs) for the B-, G-, and R-GQDs are 68, 62, and 27%, respectively. Structural characterization and theoretical calculations indicate that the quantum size effect adjusts the red shift of emission from B-GQDs to G-GQDs, and the increased content of oxygen and C═N bonds are answerable for the red emission of R-GQDs. Then, we apply the prepared multicolor GQDs as a fluorescent ink for pattern printing and multicolor anticounterfeiting. Moreover, B-, G-, and R-colors and white light-emitting diodes (LEDs) are fabricated by ultraviolet radiation as excitation. The white LEDs exhibit a color coordinate of (0.335, 0.343), a high color rendering index of 95, and a correlated color temperature of 4835 K. This research successfully expands the potential application of GQDs in the reliable anticounterfeiting, information security, and high color rendering index GQD-based LEDs.
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Biosensors-Basel
·
2022
·Vol. 12
·期 12
·1084
·
IF 5.743
Tao Tian,Wei-Yi Zhang,Hang-Yu Zhou,Li-Jing Peng,Xi Zhou,Hao Zhang,Feng-Qing Yang
In this study, the personal glucose meter (PGM) was first used as a fast and user-friendly meter for analyzing catechol (CA) based on the reduction of the mediator K3[Fe(CN)6] to K4[Fe(CN)6] in the glucose test strip. Then, an easy, low-cost, and convenient PGM-based method for detecting tyrosinase (TYR) activity and sodium benzoate (SBA) was developed on the basis of the TYR-catalyzed reaction. In this method, CA is oxidized to formo-benzoquinone by TYR, thereby reducing the residual amount of CA and the PGM readout. On the other hand, SBA can inhibit the oxidation of CA catalyzed by TYR and increase the residual amount of CA after the enzymatic reaction. Therefore, the activity of TYR is proportional to the difference in the PGM readout of CA, and the concentration of SBA is positively correlated with the residual amount of CA. After the relevant experimental conditions were systematically optimized, the proposed PGM-based method for the detection of TYR and SBA was successfully validated. The liner ranges are 1.0–103.3 U/mL and 6.25–1000 ppm, and the quantification limits are 1.0 U/mL and 6.25 ppm for TYR and SBA, respectively. Moreover, the spiked recovery tests in normal human serum and carbonate beverages (i.e., Cola, Sprite, and Fanta) were performed, and the recoveries (91.6–106.8%) further confirm the applicability of the PGM-based method in real sample analysis.Keywords:tyrosinase;sodium benzoate;personal glucose meter;enzyme sensor;carbonate beverages sample
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SENSORS AND ACTUATORS B-CHEMICAL
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2022
·
IF 9.221
Kaiqi Liu,Luminita Marin,Xinjian Cheng
In this work, fluorescent β- cyclodextrin (β-CD) based probes containing naphthalimide group were synthesized to realize the specific recognition of Hg 2+ /Hg + in aqueous system. Firstly, three small fluorescent molecules (N1, N2 and N3) with -NH 2 groups were synthesized from 4-bromo-1, 8-naphthalene anhydride . Secondly, CH CCH 2 - group was introduced into β-CD by Williamson ether formation reaction. Finally, the target probes (β-CD-PI, β-CD-PY and β-CD-TP) were obtained by Amino-Yne click reaction. These probes can efficiently recognize Hg 2+ /Hg + . β-CD-PI emits bright yellow fluorescence after binding with Hg 2+ /Hg + , which is a turn-on fluorescent probe . When the Hg 2+ /Hg + concentration exceeds 26 μM, the fluorescence intensity amplifies sharply (20 folds). The hydrophobic parts of the probes aggregated together to form a micelle-like structure due to complexation with Hg 2+ /Hg + , resulting in special micelle-sensitizing properties. Meanwhile, the HOMO-LUMO energy levels of the probes were calculated by cyclic voltammetry (CV). The probe is expected to be used for the detection of Hg 2+ /Hg + in aqueous solutions without any organic solvents.
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Journal of Environmental Chemical Engineering
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2022
·
IF 7.968
Shuang Zheng,Shujuan Yang,Zhaofeng Ouyang,Tianya Chen,Yong Kuang,Haixing Shen,Fei Yang,Yong Zhang
To obtain ultrafiltration (UF) membranes with excellent separation performances and antifouling properties, regenerated cellulose (RC) membranes with intrinsic hydrophilicity and dense structures immensely attract the attention of researchers. Herein, a novel modified RC membrane, which has high water permeability and antifouling capability, is prepared using cellulose acetate (CA) via non-solvent induced phase separation (NIPS) and green hydrolysis technology . The as-prepared membranes were investigated comprehensively by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) analyses and protein adsorption, etc. As a result, the RC membranes showed higher hydrophilicity (WCA=25.95°), thus they possessed a lower protein adsorption value of 1.9 ± 0.1 μg/cm 2 . The filtration performances were evaluated by bovine serum albumin (BSA) and endotoxin separation with dead-end filtration system. The results exhibited greater selectivity of RC membranes that BSA rejection over 98% and endotoxin remove below 0.25 EU/mL, and excellent anti-fouling properties that the flux recovery rate (FRR) over 95% and even as high as 100%. Simultaneously, the common polyethersulfone (PES) composite membranes were prepared via NIPS technology, and comprehensively compared with RC membranes to provide a theoretical basis for the practical application of RC membranes in pharmaceutical and biotechnological industries.
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PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
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2022
·
IF 3.915
Long Wu,Yun Meng,Yuhang Xu,Xiaoqin Chu
Objective The purpose of this experiment was to explore the effect of Solid lipid nanoparticles (SLNs) on improving the oral absorption and bioavailability of cinnamaldehyde (CA).Methods CA-SLNs were prepared by high-pressure homogenization and characterized by particle size, entrapment efficiency, and morphology, thermal behavior and attenuated total reflection Fourier transform infrared (ATR-FTIR). In vitro characteristics of release, stability experiments, cytotoxicity, uptake and transport across Caco-2 cell monolayer of CA-SLNs were studied as well. In addition, CA-SLNs underwent pharmacokinetic and gastrointestinal mucosal irritation studies in rats.Results CA-SLNs exhibited a spherical shape with a particle size of 44.57 ± 0.27 nm, zeta potential of −27.66 ± 1.9 mV and entrapment efficiency of 83.63% ± 2.16%. Differential scanning calorimetry (DSC) and ATR-FTIR confirmed that CA was well encapsulated. In vitro release of CA-SLNs displayed that most of the drug (90.77% ± 5%) was released in the phosphate buffer, and only a small amount of drug (18.55% ± 5%) was released in the HCl buffer. CA-SLNs were taken up by an energy-dependent, endocytic mechanism mediated by caveolae mediated endocytosis across Caco-2 cells. The CA permeation through Caco-2 cell was facilitated by CA-SLNs. The outcome of the gastrointestinal irritation test demonstrated that CA-SLNs had no irritation to the rats’ intestines. Compared with CA dispersions, incorporation of SLNs increased the oral bioavailability of CA more than 1.69-fold.Conclusions It was concluded that CA-SLNs improved the absorption across Caco-2 cell model and improved the oral administration bioavailability of CA in rats.
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Journal of Physical Chemistry C
·
2023
·
IF 3.7
Zhan-Kuo Guo,Han-Qing Chen,Hui-Lin Jiang,Bao-Xia Dong,Yun-Lei Teng
Storing and hydrogenating CO2 to CH4 is an efficient solution to alleviate the greenhouse effect and energy shortage. This work demonstrated that the CaO-captured CO2 could be selectively converted to CH4 by Ni- and hydrogen-assisted calcium looping (CaL) processes in a batch reactor. The Ni/CaO composite was first synthesized in one step at room temperature by calcium-induced hydrogenation of Ni-mixed calcium carbonate without the use of any solvent and CO2 emission. The CO2 capture properties over the Ni/CaO composite and the methanation properties of the Ni/CaCO3 composite produced after CO2 capture were then studied in a batch reactor. It was proved that the CO2 capture properties of CaO can be improved, the CaO recovering temperature can be significantly lowered, and valuable CH4 can be selectively produced by Ni- and hydrogen-assisted calcium looping processes at moderate/high temperature. The 68.58% methane yield and 100% methane selectivity were achieved under relatively mild conditions. After five Ni- and hydrogen-assisted CaL processes, the methane yield still reaches 45%. This study offers a novel energy-saving CaL process, which can be utilized for facile and selective conversion of the CaO-captured CO2 to CH4.
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JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2023
·Vol. 27
·期 6
·1411-1421
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IF 2.5
Ma Qingyang,Liu Dian,Wang Bo,Liu Wenyi,Xiong Guoyao,Liu Jinping
Despite their non-flammability, low processing cost and wide electrochemical stability window, solid-state polymer electrolytes still exhibit certain challenges, such as high operating temperature and low room-temperature ionic conductivity. Cellulose acetate (CA) is a common natural polymer derivative, which is promising as a filler in polymer electrolytes due to its rich surface functional groups, superior mechanical properties and high porosity. Herein, CA is incorporated into a unique polymer-in-salt electrolyte based on lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) and polyvinylidene fluoride-hexafluoropropylene (PVDF-HFP) to design a composite polymer electrolyte (PLCA). The influence of CA content on the overall performance of PLCA is investigated. With 10 wt% of CA, PLCA exhibits high room-temperature ionic conductivity of 4.33 × 10 −4 S cm −1 , high Li-ion transference number of 0.60 and a wide electrochemical stability window (4.8 V). The resulting LiFePO 4 |Li solid-state lithium battery delivers a specific discharge capacity of 160.17 mAh g −1 at 0.2 C, with stable cycling ability and good rate capability. CA is found to promote the dissociation of lithium salt, reduce the crystallinity of polymer and further create a new Li-ion transport pathway in PLCA, responsible for the battery performance improvement. Our work provides an opportunity to design high-performance composite polymer-in-salt electrolytes for advanced solid-state batteries.
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TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
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2022
·
IF 3.752
Xue-yi GUO,Zhao-wang DONG,Yang XIA,Pei-dong LIU,Han-ning LIU,Qing-hua TIAN
A high-purity Ti–48Al–2Nb–2Cr alloy powder with an oxygen content as low as 0.0572 wt.% and a particle size of <150 μm was produced from a mixture of TiO 2 , Al 2 O 3 , Nb 2 O 5 , and Cr 2 O 3 powders through reduction with magnesium and deoxidation with calcium. The phase and composition of the products were analyzed. The final product mainly included γ -TiAl and minor α 2 -Ti 3 Al phases, and Ti, Al, Cr, and Nb were homogenously distributed in the powder with a mole ratio of 49.73:43.51:2.05:1.98. The reduction and deoxidation mechanisms were investigated by thermodynamic modeling using the HSC Chemistry software and Pandat software based on the Ti alloy database.
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Advanced Composites and Hybrid Materials
·
2022
·Vol. 5
·期 2
·907-919
·
IF 11.806
Zhou Kecong,Wang Menglong,Zhou Yangqi,Sun Mengjun,Xie Yufeng,Yu Deng-Guang
Blended electrospinning is frequently utilized to prepare drug-loaded nanocomposites to take advantages of the nanofibers’ small diameters and large surface area. However, the homogeneous distribution of drug makes most of them embedded in the polymeric matrix, which correspondingly limits the functional applications. In the present study, a modified coaxial electrospinning was implemented, in which a pure drug (ciprofloxacin, CIP) solution was explored as a sheath working fluid to coat drug on the surface of polymer (cellulose acetate, CA) nanofibers to form a polymer@drug nanohybrid (NH). For comparison, an electrospun CA-CIP nanocomposite was prepared using a one-fluid blending process. Both NCs and NHs had linear morphologies without beads or spindles on them. CIP were embedded on the surface of CA nanofibers in the NH as crystalline nanoparticles, whereas CIP co-existed with CA in the NCs in an amorphous state. In vitro dissolution tests verified that NHs release the surface CIP in a pulsatile manner and NCs release the loaded CIP in a continuously. Antibacterial tests demonstrated that the NHs with a drug loading of 3.9% (w/w) showed a better zone of inhibition zone for Staphylococcus aureus and Escherichia coli than the NCs with a drug loading of 16.7% (w/w). Thus, the present study pioneered the way for the development of novel nanohybrids with improved functional properties. Graphical abstract
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危险品化学品经营许可证（带存储）