Analytical Methods
·
2019
·Vol. 11
·期 34
·4382-4389
·
IF 2.378
Fanglin Ming,Jingzhou Hou,Danqun Huo,Jun Zhou,Mei Yang,Caihong Shen,Suyi Zhang,Changjun Hou
A luminescent amino-functionalized metal–organic framework (Cu–MOFs) was synthesized from 2-aminoterephthalic acid and Cu(II) ions by a solvothermal method. Cu–MOFs displayed blue fluorescence with a peak at 430 nm under 330 nm excitation. Its structure was characterized by FTIR, TEM, XRD, and XPS. The fluorescence of the Cu–MOFs was quenched by Fe3+ in aqueous solutions. The limit of detection was 0.5 μM, and the linear working range extended from 2 μM to 35 μM. Additionally, a good logarithmic relationship between relative fluorescence intensity (F/F0) and Fe3+ concentrations ranging from 2 to 180 μM was obtained with a detection limit of 1.56 μM (R2 = 0.9975). No clear interference was observed when challenged with a wide variety of cations and anions. The recoveries from spiked real water samples were in the range of 91.7–107.7%, and the detection results were consistent with inductively coupled plasma mass spectrometry (ICP-MS) results. Therefore, the fluorescent sensor has great potential in environmental monitoring.
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FOOD AND AGRICULTURAL IMMUNOLOGY
·
2018
·
IF 2.568
Zhi-Li Xiao,Wei Tian,Zhen-Lin Xu,Yuan-Ming Sun
In this study, we develop a sensitive indirect competitive chemiluminescent enzyme immunoassay (ic-CLEIA) to detect cadmium (Cd) in cereals. A luminol-hydrogen peroxide chemiluminescence system catalysed by horseradish peroxidase (HRP) was used as the signal detecting system. The method showed a half-maximal inhibition concentration (IC50) of 0.5 ng/mL and a limit of determination (LOD) of 0.06 ng/mL. The assay indicated an effective linear range from 0.16 to 1.56 ng/mL. There were no obvious cross-reactivities with other metal ions, including Hg2+, Pb2+, As2+, Ag+, Fe3+, Cu2+, Cr2+, Au3+, Ca2+, Mg2+, Mn2+ and Zn2+. Recovery rates ranged from 79.2% to 120.0% for rice, maize, wheat, brown rice and glutinous rice samples. Twenty-five practical cereal samples were analysed, and the comparative analysis of the results showed a strong correlation (r = 0.984) between the CLEIA and the GFAAS methods. The results indicated that the ic-CLEIA developed was acceptable to screen for cadmium in cereal samples.
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Journal of Biomedical Nanotechnology
·
2017
·Vol. 13
·期 12
·1631-1646
·
IF 4.521
Wang Jiao,Liu Qiang,Yang Linnan,Xia Xiaofei,Zhu Rongrong,Chen Shengguang,Wang Mei,Cheng Liming,Wu Xianzheng,Wang Shilong
Cervical cancer is the fourth most common cancer in women worldwide, and existing treatments cause severe side effects and great burdens. Thus, the development of safe, inexpensive therapeutic agents is necessary. Curcumin (Cur), a well-known natural product, exerts promising anti-cancer
activities against various cancer types. However, its therapeutic efficacy is severely restrained due to rapid degradation, poor aqueous solubility, and low bioavailability. The objective of this study was to investigate the therapeutic potential of novel curcumin-loaded TPGS/F127/P123 mixed
polymeric micelles (Cur@NPT100) for cervical cancer treatment. The Cur@NPT100 exhibited an average size of approximately 19 nm, a zeta potential of around –4 mV, a drug loading of 8.18 ± 0.36%, and an encapsulation efficiency of 79.38 ± 4.65%. Unlike free Cur, Cur@NPT100
are readily dispersed in aqueous medium, showing enhanced stability and a sustained release profile over a 6-day period. In vitro cell culture experiments revealed that TPGS/F127/P123 mixed polymeric micelles (NPT100) based nanocarriers substantially promoted the selective cellular
uptake of Cur into HeLa cells rather than by non-cancerous NIH3T3 cells, inducing higher cytotoxicity and greater apoptosis and significantly increasing the percentage of cells arrested at the G2/M phase of the cell cycle. Additionally, the Cur@NPT100 facilitated more Cur accumulation in the
mitochondria and decreased the mitochondrial membrane potential. In addition, western blot assays demonstrated that Cur@NPT100 were more potent than free Cur at activating the mitochondria-mediated apoptosis pathway. In vivo results further confirmed that Cur@NPT100 exhibited a much higher
antitumor efficacy than free Cur and had excellent biocompatibility. In conclusion, Cur@NPT100 might be an effective therapeutic agent for cervical cancer.
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JOURNAL OF ELECTRONIC MATERIALS
·
2017
·Vol. 47
·期 2
·1705-1712
·
IF 1.579
Han Jing,Wang Yan,Tan Shihai,Guo Fu
Electromigration is a major reliability problem in composite solder joints. Due to the anisotropy of the β -Sn crystal structure, the Sn grain orientations present in the solder matrix dominate the principal failure mechanism in solder joints under electric current stressing. In this work, the Cu 6 Sn 5 growth behavior in Cu 6 Sn 5 -reinforced composite solder joints with three different Sn grain orientations was investigated at current density of 10 4 A/cm 2 at room temperature. Micron-sized Cu particles were added to Sn-3.5Ag solder at 2% volume fraction using an in situ method. After current stressing for 528 h, the polarity effect in the composite solder joint was greatest for an angle ( θ ) between the c -axis and electron flow direction of 30°, resulting in higher growth rate of Cu 6 Sn 5 in the solder matrix compared with composite solder joints with θ of 60° or 90°. There were no noticeable changes in the composite solder joint with θ of 90°. The growth behavior of Cu 6 Sn 5 , Cu atomic motion, and Cu diffusivity in the composite solder joints with different Sn grain orientations were analyzed in detail.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xueqi Duan,Xing Li,Qingya Yang
Due to the serious threat of excessive copper and magnesium ions to human health, it is crucial to detect copper and magnesium ions in aquatic environments. In this study, we propose a colorimetric strategy – gold nanoparticles (AuNPs) modified by 5-(3-aminophenyl)-1H-tetrazole (TA@AuNPs) for the rapid and portable identification of copper and magnesium ions in water. As the concentration of the target metal ions increases, the colorimetric principle (TA@AuNPs) causes the aggregation of the AuNPs system, shifts of the surface plasma resonance (SPR) absorption peak, and a change of system colors (wine-red to gray-blue). The advantages of this work: 1) the detection process is simple without complex pretreatment; 2) the concentration of the target ions could be quickly detected within 3 min by Standard Color Cards; 3) it can selectively detect two kinds of metal ions (Cu 2+ and Mg 2+ ) with high specificity in the presence of other interfering ions; 4) It eliminates the interference of calcium ions in the detection of magnesium ions; 5) It has excellent linearity and low detection limit (for Cu 2+ : R 2 = 0.94, LOD = 30.0 μM by the naked eye and 0.229 μM through ultraviolet–visible spectroscopy; for Mg 2+ : R 2 = 0.96, LOD = 300 μM by the naked eye and 0.653 μM through ultraviolet–visible spectroscopy). Furthermore, the colorimetric mechanism of the present work has been comprehensively demonstrated through DLS, TEM, zeta potential analysis, FT-IR, UV–vis and Gaussian calculations.
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JOURNAL OF MOLECULAR STRUCTURE
·
2024
·
IF 4
Xueqi Duan,Guona Li,Zhijian Jia,Hongzhen Xie,Xing Li
Copper is an essential element in the human body. Excess accumulations of copper, however, would become a potential threat. Therefore, it is of great significance to detect copper ions. Owing to their controllable morphology, dispersal characteristics, high extinction coefficient, and easily functionalized surfaces, gold nanoparticles (AuNPs) have been highly employed as attractive sensing probes for environmental and biological analyses. We herein propose an eco-friendly colorimetric strategy based on AuNPs modified with 3-pyridinylboronic acid (PA) for sensitive and selective detection of copper ions (Cu 2+ ) in water at trace level. The color changes of the system from wine-red to gray-blue with increasing amounts of copper ions is due to the binding of AuNPs modified with 3-pyridinylboronic acid to copper ions, which in turn leads to the aggregation of AuNPs with fine anti-interference. Strengths of the work: 1) rapid response time without complex pre-treatment; 2) high sensitivity with low limit of detection (LOD) and the good linear relationship ( R 2 = 0.98, LOD = 3.0 μM by the naked eye and 72 nM by ultraviolet-visible spectroscopy); 3) high selectivity under other interfering ions. In addition, the detection mechanism of this work has been successfully confirmed by density functional theory (DFT), transmission electron microscopy (TEM), dynamic light scattering (DLS), X-ray diffraction (XRD), Zeta potential analysis and ultraviolet-visible spectroscopy (UV–vis).
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Analytical Methods
·
2012
·Vol. 4
·期 8
·2441-2446
·
IF 1.547
Qian Zhang,Tao Liang,Lingqing Wang,Hongying Cao
A selective pressurized liquid extraction (SPLE) method has been optimized for the determination of polycyclic aromatic hydrocarbons (PAHs) in soil samples. The method comprises a fully automated extraction and on-line clean-up procedure by inclusion of sorbents in the extraction cells. The contributing parameters of SPLE including type of solvent, static extraction time, number of extractions, extraction temperature, nature and amount of sorbents were investigated. The optimal extraction was performed at 70 °C for 10 min (static extraction time) cycled once using n-hexane/methylene chloride (50 : 50, v/v) and the sorbents in the extraction cells were 3 g of alumina and 2 g of silica gel. The collected extracts from the cells, after pre-concentration, were clean enough for direct injection into GC-MS. Validation of the SPLE technique was performed, with the recovery rates for 16 PAHs in the range of 75–103%, and the relative standard deviation (RSD) was generally less than 10%. Method detection limits (MDL) were in the ranges of 0.001–0.080 μg kg−1 for the GC-MS analyses. Finally, the method was successfully used to evaluate the cultivated soils in Beijing, China.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2015
·
IF 2.999
Fang Cheng,Yongchang Liu,Zongqing Ma,Huijun Li,M. Shahriar Al Hossain
The un-doped Mg 11 B 2 and Cu-doped Mg 11 B 2 bulks using 11 B as a boron precursor were fabricated by solid-state reaction and sintered at different temperature in present work. By analyzing the sintering process, it was found that 11 B original powder is more reactive and can react with Mg severely even at low temperature before Mg melting, which leads to the formation of refined Mg 11 B 2 grains. Consequently, the critical current density of Mg 11 B 2 sample prepared in this work is higher than that of natural MgB 2 . Furthermore, it was found that proper Cu addition could obviously accelerate the reaction between Mg and 11 B and promote the formation of Mg 11 B 2 due to the appearance of Mg–Cu liquid at low sintering temperature before Mg melting. On the other hand, Cu addition also introduced more MgCu 2 impurity, leading to a relatively lower critical current density on the whole. Interestingly, the critical current density of the Cu doped sample sintered at 800 °C is surprisingly enhanced at the low field, compared with that of the corresponding un-doped one. This is due to the peritectic reaction which generated small-sized MgCu 2 occurred that at 800 °C, providing MgCu 2 pinning centers well-distributed in the MgB 2 matrix.
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ECOLOGICAL INDICATORS
·
2015
·
IF 3.444
Yanjie Qi,Shibin Hu,Shouliang Huo,Beidou Xi,Jingtian Zhang,Xiaowei Wang
Sediment samples were collected from the Chaohu Lake basin to investigate the spatial distribution and historical deposition behaviors of 17 perfluoroalkyl substances (PFASs). Concentrations of the total PFASs (∑PFASs) in limnetic sediments ranged from 0.719 to 2.429 ng/g dry weight (dw), with an average of 1.449 ng/g dw. A clear gradient in the spatial distribution was observed from west to east in surface sediments of Lake Chaohu. Perfluorooctane sulfonic acid and perfluorooctanoic acid were predominant in limnetic sediments, with an average of 0.383 and 0.275 ng/g dw, respectively. The ∑PFASs concentrations in riverine sediments were the highest in the Shiwuli River, followed by the Nanfei River. PFASs in riverine sediments indicated that industrial discharge and urban runoff played key roles in PFAS distribution and pollution levels. In vertical profiles, concentrations of the ∑PFASs and PFAS congeners in three sediment cores generally increased with decreasing depths, indicating that the input history of the ∑PFASs could be attributed to the development of industrialization and urbanization in the Chaohu Lake basin. The correlations between PFASs and sedimentary characteristics, organic carbon, nutrients and inorganic salts suggested that both hydrophobic and electrostatic effects played important roles in PFAS distribution and pollution levels in sediments of Lake Chaohu.
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TETRAHEDRON
·
2015
·
IF 2.641
Biquan Xiong,Kui Zeng,Shanshan Zhang,Yongbo Zhou,Chak-Tong Au,Shuang-Feng Yin
A novel copper-catalyzed method for the direct esterification of P(O)–OH compounds using phenols as efficient esterification reagents is illustrated. It is a simple way to generate a broad spectrum of functionalized O -aryl phosphinates , phosphonates , and phosphates from basic starting materials with moderate to excellent yields.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Wei Xiao,Qing Zhang,Dong Hui You,Nian Bing Li,Guang Ming Zhou,Hong Qun Luo
Copper is an essential trace element in the human body, and its level is directly related to many diseases. While the source of copper in human body is mainly intake from food, then the detection of copper ions (Cu 2+ ) in food becomes crucial. Here, we synthesized a novel probe ( E )-3-hydroxy-2-styryl-4 H -benzo[h]chromen-4-one ( NSHF ) and explored the binding ability of NSHF for Cu 2+ using nuclear magnetic resonance hydrogen spectroscopy ( 1 H NMR), high-resolution mass spectrometry (HRMS), Job's plot method and density functional theory (DFT). NSHF shows the advantages of fast response time, good selectivity and high sensitivity for Cu 2+ . The fluorescence intensity ratio (F/F 0 ) of NSHF shows a good linear relationship with the concentration of Cu 2+ and the detection limit is 0.061 μM. NSHF was successfully applied to the detection of Cu 2+ in real samples. In addition, a simple and convenient Cu 2+ detection platform was constructed by combining NSHF with a smartphone and a UV lamp, which can realize the rapid detection of Cu 2+ . This work provides an effective tool for the real-time detection of Cu 2+ .
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GREEN CHEMISTRY
·
2024
·Vol. 26
·期 18
·9888-9898
·
IF 9.3
Chongyan Chen,Shuguang Shen,Jie Wang,Yongmei Liu,Xingting Guo,Lili Zhang,Jing Li
The electroconversion of carbon dioxide (CO2) into value-added chemicals has attracted widespread attention worldwide. Exploring efficient catalysts and designing reasonable reactants have become popular research directions in the strategy of coupling anode and cathode reactions. Herein, we report the construction of a self-supporting bifunctional Sn–SnSx electrode using a one-step electrodeposition method. The valence states of Sn at the Sn–SnSx surface are Sn4+, Sn2+ and Sn0, and the electrode exhibits excellent performances for the carbon dioxide reduction reaction (CO2RR) and glucose oxidation reaction (GOR), respectively. For the CO2RR, the Sn–SnSx electrode produced formate with a faradaic efficiency (FE) of 93.3% and a stability of 36 h. Meanwhile, tin sulfides were first applied in anodic oxidation and a high FE of 88% was achieved for formate production in the GOR. Impressively, Sn–SnSx as a bifunctional electrode achieved co-production of formate at both the anode and cathode in the integrated electrolyzer coupled with the CO2RR and GOR. This coupling process combines the technical means of “electrooxidation–electroreduction” with the choice of reactants “CO2–C6H12O6”, resulting in FE values of 93.9% and 87.4% at the cathode and anode for the production of formate, as well as a 58.3% electrical energy saving for formate production in comparison with the traditional CO2RR coupled with the water oxidation reaction.
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