Jove-Journal of Visualized Experiments
·
2017
·
IF 1.232
Yanrong Zheng,Zhe Shen,Xiaoli Wu,Lei Jiang,Weiwei Hu,Zhong Chen,Xiangnan Zhang
Stroke is one of the leading causes of mortality and disability worldwide, with limited therapeutic approaches. As an endogenous strategy for neuroprotection, postconditioning treatments have proven to be promising therapies against cerebral ischemia. However, complicated procedures and potential safety issues limit their clinical application. To overcome these disadvantages, we have developed acidic postconditioning (APC) as a therapy for experimental focal cerebral ischemia. APC refers to the mild acidosis treatment by inhaling CO2 during reperfusion following ischemia. Here we present two models to execute APC in vitro and in vivo, respectively. The oxygen-glucose deprivation (OGD) treatment of mice and the corticostriatal occlusion and middle cerebral artery occlusion (MCAO) of mice were employed to mimic cerebral ischemia. APC can be simply achieved by transferring brain slices to acidic buffer bubbled with 20% CO2, or by mice inhaling 20% CO2. APC showed significant protective effects against cerebral ischemia, as reflected by tissue viability and brain infarct volume.
研究领域:
神经科学
·
医学
·
实验生物学
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Yueyao Liang,Ruquan Zhang,Zhihua Qiao,Chongli Zhong
Supported metal–organic framework (MOF) membranes are promising candidates for energy-efficient natural gas purification, but the preparation of ultrathin MOF membranes supported by polymer substrates remains challenging. Herein, we proposed a polymer collaboration method for preparing ultrathin two-dimensional MOF membranes on polymer support layers. Cu(II) meso-tetra (4-carboxyphenyl) porphyrin (CuTCPP) membranes having thicknesses as low as <10 nm were formed in situ because of the high density of heterogeneous nucleation sites in a polyvinyl alcohol-Cu 2+ interface layer and the controlled anisotropic growth of nanocrystals enabled by a polyvinylpyrrolidone (PVP) surfactant. The prepared CuTCPP membranes showed excellent CO 2 /CH 4 separation performance, yielding a high permeance of 4560 GPU and a moderate selectivity of 31.8. Furthermore, the prepared CuTCPP membranes also displayed good CO 2 /N 2 separation performance, having a CO 2 permeance of 3200 GPU and a CO 2 /N 2 selectivity of 36. The thickness of CuTCPP membranes can be controlled by varying the concentration of metal ions in the organic interface layer. This preparation method can not only fix the active sites for membrane formation but also control the morphology of crystal growth and is applicable to membrane fabrication using other porous MOFs.
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
FUEL
·
2016
·
IF 3.611
Tingting Cheng,Yehua Han,Yanfen Zhang,Chunming Xu
A three-step supercritical CO 2 extraction was used for selective fractionation of fast pyrolysis bio-oil. Oxygen-containing compounds in bio-oil and its fractions were characterized using infrared spectroscopy (IR), 1 H nuclear magnetic resonance spectroscopy (NMR), gas chromatography–mass spectrometry (GC–MS) and negative-ion electrospray ionization (ESI) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). With appropriate optimization of extraction parameters, lipids, hemicellulose, lignin and condensed aromatics were found enriched in three different fractions. The molecular composition and compound classes were identified by combined analytical techniques, and the selectivity of the fractionation was proved. The compound-type-specific fractionation also facilitated the following characterization and provided insights into the chemical composition of bio-oil. Results indicated that CO 2 supercritical fluid extraction was potential for bio-oil preprocessing.
研究领域:
化学工程
·
分析化学
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DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2021
·
IF 8.198
Hongbing Song,Yongjie Wang,Yule Liu,Lei Chen,Bingxiao Feng,Xin Jin,Yu Zhou,Tingting Huang,Meng Xiao,Fangmin Huang,Hengjun Gai
Three ionic liquid (IL) monomers consisting of one, two, and four benzene rings were designed with 2-phenylimidazole and polymerized with α,α′-dichloro-p-xylene (DCX) and formaldehyde dimethyl acetal (FDA) to form a series of novel poly(ionic liquid)s (PILs). In this process, the designed ILs were employed as active ionic sites, and DCX and FDA were selected as cross-linkers. Self-condensation of the cross-linker provided a large specific surface area for the hypercross-linked organic framework, while co-condensation between the cross-linker and IL introduced active sites to the framework. The obtained porous hypercross-linked PILs not only promoted CO2 capture and the selective absorption of CO2/N2 but also showed good activity for the cycloaddition of epoxide with CO2. HP-[BZPhIm]Cl-DCX-1 with a large surface area (763 m2·g–1) showed a CO2 uptake capacity of 1.47 mmol·g–1 and offered a 98.9% yield of the CO2 cycloaddition product with epichlorohydrin at 80 °C for 24 h under 0.1 MPa CO2 pressure. The designed PILs provide an important reaction for CO2 utilization.
研究领域:
材料科学
·
催化化学
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DOI
高影响因子
CHINESE JOURNAL OF CATALYSIS
·
2017
·
IF 2.813
Ling Zhang,Xue Liu,Rui-Xia Yang,Nian-Yu Huang,Wei-Qiao Deng
Covalent triazine-based frameworks (CTFs) are important microporous materials with a wide range of applications. Here, we demonstrate an environmentally benign and economic synthetic pathway to CTFs. The monomers used for CTFs, aromatic nitriles , were obtained by cyanation using nontoxic potassium hexacyanoferrate(II) in place of commonly used toxic cyanides. Then, the CTFs were synthesized by trimerization of the corresponding cyano monomers in molten zinc chloride . A series of CTFs was synthesized, and the highest Brunauer-Emmett-Teller surface area measured in this series was 2404 m 2 /g. Among the synthesized CTFs, CTF DCP exhibited excellent CO 2 adsorption properties, with a CO 2 uptake of 225 mg/g at 0 °C.
研究领域:
材料科学
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环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
APPLIED ENERGY
·
2017
·
IF 7.182
Ke Wang,Zhongyun Zhou,Pengfei Zhao,Zeguang Yin,Zhen Su,Ji Sun
Highly efficient NaF-doped Li 4 SiO 4 sorbents were synthesized by sacrificial carbon template technology to overcome their typical kinetic limitations at low CO 2 concentrations. The samples were characterized by XRD , SEM , N 2 adsorption, XPS , differential scanning calorimetry (DSC), and thermogravimetric analyses (dynamic and isothermic). The results showed that co-doped sodium and fluorine were substituted for lithium and oxygen, respectively. Such doped features induced a high concentration of Li-O sites on the molten surface when absorbing CO 2 in a relatively wide temperature range (475–575 °C). This favorable characteristic greatly facilitated surface chemisorption processes, accelerated the transport of Li + and O 2− , and decreased the CO 2 diffusion resistance. Therefore, 3 wt.% NaF doping was used to reach a maximum absorption capacity (>33.0 wt.%) in a wide temperature range (475–575 °C) in 15 vol.% CO 2 . Moreover, the high capacity was maintained over 10 sorption/desorption cycles, suggesting that NaF-doped Li 4 SiO 4 sorbents have high potential for CO 2 capture.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2026
·Vol. 18
·期 30
·41103-41112
·
IF 7.8
Sun Jiping,Zhang Hong,Wang Zhixing,Li Guangchao,Wu Bichao,Yang Sheng,Liu Min,Wang Jiexi
Developing acidic electrochemical CO 2 reduction reaction (CO 2 RR) systems can alleviate carbonate clogging in gas diffusion electrodes (GDEs), offering an efficient way to convert CO 2 at industrial-level current densities ( J > 200 mA cm –2 ). However, it comes at the cost of aggravating competitive hydrogen evolution reactions (HERs). Breaking this intrinsic selectivity–stability trade-off requires synergistic H 2 O/CO 2 management. As a central component of GDEs, the gas diffusion layer (GDL) critically governs gas (CO 2 )–liquid (H 2 O) transport balance. This work proposes a gradient pore-hydrophobicity cooperation strategy for synergistic H 2 O/CO 2 management to achieve efficient acidic CO 2 RR. Paired with commercial Ag catalysts, the Ag-GDEs exhibit an impressive CO Faraday efficiency of 97.26% at 400 mA cm –2 within a pH = 2.0 environment. Furthermore, in situ differential electrochemical mass spectrometry confirms the distinct mass transfer kinetics induced by GDL architectures. Lattice Boltzmann modeling simulations corroborate the effects of the gradient pore-hydrophobicity synergy on CO 2 and H 2 O distribution in GDLs. This work presents an effective approach to the rational design of GDLs and the collaborative liquid–gas management for efficient CO 2 RR.
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产品关联
DOI
PubMed
高影响因子
FUEL
·
2021
·
IF 6.609
Hao Shen,Zihao Yang,Xiaochen Li,Ying Peng,Meiqin Lin,Juan Zhang,Zhaoxia Dong
Hydraulic fracturing and CO 2 flooding are extensively used in low-permeability reservoirs to enhance oil recovery (EOR). However, due to the serious heterogeneity of the formation, CO 2 is prone to break through the oil-bearing zone prematurely, which leads to the decrease of the swept volume. Conventional blocking agents have some defects such as difficult injection, poor stability and weak sealing strength. Therefore, it is critical to developing a new type of channeling blocking agent for low-permeability fractured reservoirs. In this study, ten kinds of chemicals with tertiary amino groups are filtered for the most effective CO 2 -responsive agent, which turns out to be N, N-Dimethyl erucamide tertiary amine (DMETA). Subsequently, rheological properties, response performance, and microstructure of the optimum agent are researched systematically through rheological experiments, CO 2 -response processes and Cryo-TEM. The results show that the viscosity of the DMETA solution can increase to nearly 605,700 mPa·s by self-assembly into wormlike micelles (WLMs). And it can be reversibly circulated between low viscosity and high viscosity by alternately introducing and removing CO 2 , which endows it with the ability to healing its viscoelasticity under an environment full of CO 2 . A new method based on optical microrheology is proposed to study the viscoelastic properties of WLMs under no external force. The experiments prove that the network structure is not stable after formation, but remains in a continuous process of separation and reconstruction as “a living polymer.” Furthermore, the plugging performance and EOR capacity are evaluated using fractured tight cores. The experiments demonstrate that the optimum agent can effectively restrain gas channeling and enhance recovery factor by 21.7%. We expect our work can provide insights for the synthesis of CO 2 -responsive WLMs and guidance for retarding gas channeling during CO 2 flooding in low permeability reservoirs.
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产品关联
DOI
高影响因子
ACS Applied Engineering Materials
·
2025
·
IF 3.5
Yazhou Shuang,Fang Wang,Weihao Zhao,Hongkang Wang,Zelin Ma,Jie Jian,Shiyuan Wang,Jiulong Wang,Longyang Li,Pengfei Guo,Qian Ye,Fei Xu,Hongqiang Wang
Vanadium oxide (VOx)-based catalysts for propane (C3H8) dehydrogenation (PDH) demonstrate excellent redox properties due to the multivalent property of vanadium; however, the unsatisfactory catalytic efficiency and recondite catalytic mechanisms seriously restrict their widespread applications. Herein, we proposed the doping of cobalt oxide (CoOx) species into VOx supported on alumina for simultaneously facilitating the catalytic performance in PDH with (oxidative) and without CO2 (nonoxidative). The CoOx-doped VOx species are uniformly impregnated onto alumina supports through a ligand-free wet chemical impregnation method, without any additives. The results show that the CoOx doping modulates the electronic interactions between VOx species, thus increasing the reductive capability of the catalyst and mitigating the competitive absorption of CO2 with C3H8. Consequently, superior catalytic performances are achieved in both nonoxidative and CO2-oxidative PDH reactions compared to pristine VOx species without CoOx doping. Otherwise, the dry reforming of C3H8 is significantly inhibited compared to pristine CoOx species without VOx doping. Notably, a higher and impressive conversion rate up to 55.5% for target products (C3H6) is achieved in nonoxidative PDH compared to CO2-oxidative PDH on the CoOx-doped VOx catalyst, indicative of the competitive adsorption between reactants (CO2 and C3H8) during the catalytic process. This study provides a forward-looking mechanism to establish separate reaction pathways for each reactant (CO2 and C3H8) to improve mass transfer, thereby enhancing the efficiency of CO2-oxidative PDH.
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产品关联
DOI
高影响因子
ENERGY & FUELS
·
2025
·
IF 5.3
Xingyu Lin,Hongsheng Lu,Ruoxin Zhang,Yingjiang Chen,Li Wang,Baiwen Huang
Underground CO2 storage is a key strategy for mitigating climate change by reducing greenhouse gas emissions. However, the heterogeneity of reservoirs poses challenges to effectively storing CO2 in designated spaces. In this study, an environmentally friendly CO2-responsive ionic liquid (IL) DA-Ch was synthesized by choline hydroxide (Ch) and dodecanedioic acid (DA) at a 2:1 mol ratio. The innovative system enhances the sweep efficiency and storage capacity of CO2 by enabling the transition of DA-Ch ILs aqueous solution from low-viscosity liquids (0.5 mPa·s at 0.1 mol/L) to solid microparticles upon CO2 introduction. After CO2 injection, DA precipitated again from the DA-Ch ILs aqueous solution with a volume mean particle size of micrometers, even under high-salinity conditions. This phase transition effectively plugs preferential flow channels, expanding CO2 storage space by 82% compared to conventional CO2 flooding. Our findings propose a novel, sustainable approach to address gas channeling challenges in subsurface CO2 storage, offering dual benefits for carbon sequestration and enhanced oil recovery.
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产品关联
DOI
高影响因子
Nano Research
·
2021
·Vol. 15
·期 2
·1310-1318
·
IF 8.897
Ullah Sami,Liu Yu,Hasan Maria,Zeng Wenwen,Shi Qitao,Yang Xiaoqin,Fu Lei,Ta Huy Q.,Lian Xueyu,Sun Jingyu,Yang Ruizhi,Liu Lijun,Rümmeli Mark H.
Graphene doping continues to gather momentum because it enables graphene properties to be tuned, thereby affording new properties to, improve the performance of, and expand the application potential of graphene. Graphene can be chemically doped using various methods such as surface functionalization, hybrid composites (e.g., nanoparticle decoration), and substitution doping, wherein C atoms are replaced by foreign ones in the graphene lattice. Theoretical works have predicted that graphene could be substitutionally doped by aluminum (Al) atoms, which could hold promise for exciting applications, including hydrogen storage and evolution, and supercapacitors. Other theoretical predictions suggest that Al substitutionally doped graphene (AlG) could serve as a material for gas sensors and the catalytic decomposition of undesirable materials. However, fabricating Al substitutionally doped graphene has proven challenging until now. Herein, we demonstrate how controlled-flow chemical vapor deposition (CVD) implementing a simple solid precursor can yield high-quality and large-area monolayer AlG, and this synthesis is unequivocally confirmed using various characterization methods including local electron energy-loss spectroscopy (EELS). Detailed high-resolution transmission electron microscopy (HRTEM) shows numerous bonding configurations between the Al atoms and the graphene lattice, some of which are not theoretically predicted. Furthermore, the produced AlG shows a CO 2 capturability superior to those of other substitutionally doped graphenes.
研究领域:
材料科学
·
物理化学
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2024
·
IF 3.2
Yu Su,Qian Zhou,Ting Hu,Peng Li,Yu Zhu,Qing-Wen Han,Ru-An Chi,Dong-Sheng Li
Tin-oxo clusters, as molecular model compounds of tin oxide materials, have attracted increasing attention. Although various tin-oxo clusters have been obtained, the systemic studies on ligand functionalization of tin-oxo clusters remain to be well developed. In this study, we adopted 3-aminopyrazine-2-carboxylic acid (HAPZC) as the functionalized ligand, and successfully synthesized a novel tin-oxo cluster [( n -BuSn) 12 (OH) 6 O 14 (APZC) 2 ]·2H 2 O ( CTGU-SnC-3 ). Due to the functionalization of the APZC ligands, the structure and charge of Sn 12 cage in CTGU-SnC-3 are all different from those of reported cationic football cage. This Sn 12 cage in CTGU-SnC-3 presents the interesting low-symmetrical football framework with the functionalized ligands. Different from the reported cationic football cages, the CTGU-SnC-3 is charge-neutral structure without any counteranions. Moreover, the CTGU-SnC-3 exhibits hydrophobic behavior and catalytic activity in electrocatalytic CO 2 reduction reaction.
研究领域:
材料化学
·
分子簇化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）