Plant Methods
·
2019
·Vol. 15
·期 1
·1-13
·
IF 3.17
Song Yadi,Chen Shang,Wang Xiujuan,Zhang Rui,Tu Lichan,Hu Tianyuan,Liu Xihong,Zhang Yifeng,Huang Luqi,Gao Wei
Background Tripterygium wilfordii Hook. f. ( T. wilfordii ) is an important medicinal plant with anti-inflammatory, immunosuppressive and anti-tumor activities. The main bioactive ingredients are diterpenoids and triterpenoids, such as triptolide, triptophenolide and celastrol. However, the production of terpenoids from original plants, hairy roots and dedifferentiated cells (DDCs) are not satisfactory for clinical applications. To find a new way to further improve the production of terpenoids, we established a new culture system of cambial meristematic cells (CMCs) with stem cell-like properties, which had strong vigor and high efficiency to produce large amounts of terpenoids of T. wilfordii . Results CMCs of T. wilfordii were isolated and cultured for the first time. CMCs were characterized consistent with stem cell identities based on their physiological and molecular analysis, including morphology of CMCs, hypersensitivity to zeocin, thin cell wall and orthogonal partial least square-discriminant analysis, combination of transcriptional data analysis. After induction with methyl jasmonate (MJ), the maximal production of triptolide, celastrol and triptophenolide in CMCs was 312%, 400% and 327% higher than that of control group, respectively. As for medium, MJ-induced CMCs secreted 231% triptolide and 130% triptophenolide at the maximum level into medium higher than that of control group. Maximal celastrol production of induced CMCs medium was 48% lower than that of control group. Long-term induction significantly enhanced the production of terpenoids both in cells and medium. The reason for increasing the yield of terpenoids was that expression levels of 1 - deoxy - d - xylulose - 5 - phosphate synthase ( DXS ), 1 - deoxy - d - xylulose - 5 - phosphate reductoisomerase ( DXR ) and hydroxymethylglutaryl - CoA synthase ( HMGS ) were upregulated in CMCs after induction. Conclusions For the first time, CMCs of T. wilfordii were isolated, cultured, characterized and applied. Considering the significant enrichment of terpenoids in CMCs of T. wilfordii , CMCs could provide an efficient and controllable platform for sustainable production of terpenoids, which can be a better choice than DDCs.
研究领域:
植物生物技术
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植物化学
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药用植物
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2026
·
IF 5.4
Jianyu Li,Wenbo Li,Qiong He,Ruiqing Luo,Chiyang He
Synthesis of moderate–sized uniform spherical covalent organic frameworks (COFs) within 10–50 μm is crucial for their applications in separation fields, while the spherical 2D COFs with such particle sizes has not been reported till now. Herein, a type of moderate–sized spherical 2D COF (TFB–BD COF) with uniform size within 10–50 μm was size–controllably synthesized via an ‘emulsion polymerization–crystallization’ strategy. The obtained TFB–BD COF showed monodisperse full–spherical morphology, good crystal structure and uniform controllable particle sizes. Moreover, another spherical 2D COF (TAPT–PDA COF) with particle size of 15 μm was also synthesized through a similar method for investigating the application potential of the spherical 2D COFs. As an application case, the spherical TAPT–PDA COF was used as the adsorbent for the disperse solid–phase extraction (d–SPE) of bisphenol F (BPF). The adsorbent showed good adsorption selectivity, high adsorption capacity, fast binding kinetics, good reusability (at least four cycles) and high enrichment factor (60 folds). By combining this d–SPE technique with high–performance liquid chromatography, a new analytical method was established for determination of trace BPF in water samples and an orange juice with recoveries of 94.8–101.6% and LOD of 0.56 ng/mL. The synthesis strategy proposed in this work opens a way for size–controllably synthesizing moderate–sized spherical 2D COFs, and the developed analytical method provides a viable path for detecting trace BPF in water samples and beverages.
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Canadian Journal of Chemistry
·
2020
·Vol. 98
·期 10
·
IF 1.171
Cheng Cao,Xingmei You,Lei Feng,Guanghong Luo,Guoren Yue,Xiangdong Ji
Two new chromogenic sensors 1-(2-hydroxyphenyl)-3-(4-nitrophenyl)thiourea 1 and 1-(3-hydroxypyridin-2-yl)-3-(4-nitrophenyl)thiourea 2 bearing nitrophenyl and thiourea groups were designed and synthesized by one-step procedure and characterized through 1H NMR, 13C NMR, FTIR, and MS. The anion recognition property of the receptors was studied via naked-eye detection, UV–vis, and 1H NMR. Based on the existence of amino gen and hydroxyl moieties in receptors, receptors 1 and 2 exhibit obvious selectivity by the redshift of UV–vis signals, colour changes through naked-eye detection, and binding effects for F–, H2PO4–, and Ac–. Surprisingly, the detection limits of receptor 1 for F– and Ac– were calculated to be 5.45 × 10−7 and 2.11 × 10−7 (mol/L)−1, respectively, which indicated that F– and Ac– can be identified with high sensitivity by receptor 1. Besides, simple “test strips” were developed and were used as sensors for recognition of F–, H2PO4–, or Ac– in DMSO solution. Lastly, the mechanisms of the recognition process were studied through DFT calculation and 1H NMR titration.
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DALTON TRANSACTIONS
·
2019
·Vol. 48
·期 15
·4823-4829
·
IF 4.052
Jian Lin,Qi Liu,Zenghui Yue,Kariem Diefenbach,Liwei Cheng,Yuejian Lin,Jian-Qiang Wang
Expanding the family of f-element bearing molybdate iodates via hydrothermal reactions has yielded ten new rare-earth molybdate iodates with two distinct phases, Ln(MoO2)(IO3)4(OH) (LnMoIO-1, Ln = Ce and Pr) and Ln(Mo2O7)(IO3)(H2O)2 (LnMoIO-2, Ln = Gd–Yb, and Y), as well as the first thorium molybdate iodate, ThF(MO4)(IO3) (ThFMoIO). All three structures exhibit three dimensional frameworks and are exclusively built from lanthanide/actinide polyhedra bridged by molybdates and iodates. Furthermore, the coordination versatility of molybdates (octahedral, square pyramidal, and tetrahedral geometries) results in a diversity of structures. The effect of the lanthanide contraction on the compositions and structures is clearly observed, showing the increase in hydration from the early to late lanthanide analogues and the decrease in unit cell dimensions and the average Ln–O bonding distances across the same structure type. Single crystal X-ray diffraction studies reveal that LnMoIO-1 (Ln = Ce and Pr) crystalize in a noncentrosymmetric space group P21 and the second-harmonic generation (SHG) measurement shows a response of 5 × KDP for PrMoIO-1. In addition, CeMoIO-1 crystallizes as orange coloured tablets which are semiconducting in nature with a band gap of 2.41 eV.
研究领域:
无机化学
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材料科学
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固态化学
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光学材料
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晶体工程
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Small
·
2023
·Vol. 20
·期 13
·2306561
·
IF 13.3
Yanling Zhuang,Quan Zong,Yuanzhe Wu,Chaofeng Liu,Qilong Zhang,Daiwen Tao,Jingji Zhang,Jiangying Wang,Guozhong Cao
The electrochemical properties of vanadium-based materials as cathode materials for aqueous zinc ion batteries are still restricted by low conductivity, sluggish reaction kinetics, and poor structural stability. Herein, the [VO 6 ] octahedron, as the basic unit of vanadium-oxide layer of ammonium vanadates (NH 4 V 4 O 10 , denoted as NVO), is incorporated by F atoms to regulate the coordinated environment of vanadium. Density functional theory (DFT) calculations and experimental results show that both physicochemical and electrochemical properties of NVO are improved by F-doping. The enhanced electronic conductivity accelerates the electron transfer and the expanded interlayer spacing expedites the diffusion kinetics of zinc ions. As a result, the F-doped NVO (F-NVO) electrode shows a high discharge capacity (465 mAh g −1 at 0.1 A g −1 ), good rate capability (260 mAh g −1 at 5 A g −1 ), and long-term cycling stability (88% capacity retention over 2000 cycles at 4 A g −1 ). The reaction kinetics and energy storage mechanism of F-NVO are further validated by in situ and ex situ characterizations.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
·
IF 5.2
Bochen Jiang,Yanhua Lei,Kai Sun,Qing Chen,Fei Zhang,Yan An,Yuliang Zhang,Yi Lin,Yuan Yuan,Tao Liu,Xiaofeng Li
Ice accumulation is an important challenge for daily life and industrial production. The photothermal effect offers a promising approach for active de-icing to address this issue. While the photothermal effect of polyphenol-metal ion complex is extensively studied in photothermal cancer therapy, its application in de-icing remains relatively unexplored. Herein, a durable photothermal superhydrophobic coating was designed by combining F-SiO 2 @Tp/Fe (Tea polyphenol-Fe 3+ ) nanoparticles and silicone resin using a one-step spray method. Due to the unique micro-nano structure, the resulting coating exhibited excellent superhydrophobicity, characterized by water contact angle (CA) of up to 159° and sliding angle (SA) of less than 2.5°. Additionally, the coating demonstrated reliable mechanical durability and chemical stability, as evidenced by its good performance in sandpaper abrasion, tape peeling and electrochemical corrosion tests. Moreover, owing to the efficient photothermal conversion of F-SiO 2 @Tp/Fe nanoparticles , surface temperature of the coating can quickly reach 81 ℃ under 1 kW/m 2 simulated sunlight irradiation (1 Sun). The prepared coating exhibits over three times delayed icing time under 1 sun irradiation at − 25 °C in comparison to the absence of light. And the coating also exhibits stable de-icing and defrosting cycle performance. These findings demonstrate effective synergistic effect of anti-icing and de-icing in the F-SiO 2 @Tp/Fe photothermal superhydrophobic coating, showcasing its promising application potential in practical engineering.
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CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Weirui Chen,Siyou Fu,Xukai Li,Jing Wang,Xunan Ning,Liying Bin,Ping Li,Bing Tang,Laisheng Li
Photocatalytic ozonation (PCO) was a novel water treatment method, but the low photo-generated electron ( e - ) utilization and ambiguous ROS formation mechanism restrained its performance. Herein, C vacancy and F co-decorated g-C 3 N 4 (FCN_Cv) was designed to accelerate the PCO performance with sodium p -perfluorinated nonoxybenzenesulfonate (OBS) acting as model pollutant. Comparative characterizations revealed that FCN_Cv remained the inherent structure of g-C 3 N 4 (BCN), and had an enhanced conduction band potential, narrower band gap and longer e - lifetime. FCN_Cv exhibited the greater activity over BCN, with 99.3 % OBS removal in 30 min but only 78.3 % for BCN during PCO process. •OH was the main ROS for degrading OBS. The greater •OH yield was obtained by FCN_Cv PCO process because of the increase of e - utilization. On one hand, the two electrons reduction of O 2 into H 2 O 2 on FCN_Cv was accelerated, which triggered the peroxone reaction between photogenerated-H 2 O 2 and O 3 . On the other hand, the direct one electron reduction of O 3 by e - also accounted for •OH generation. 17 kinds of intermediates were detected and the OBS degradation routes were inferred, which was involved with hydroxylation, C-O cleavage and aromatic ring opening reactions. Overall, this study demonstrated the feasibility of decorating F element and C vacancy on g-C 3 N 4 in enhancing e - utilization and •OH generation during PCO process as well as deepened the understanding of fate of OBS in PCO process.
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MATERIALS CHEMISTRY AND PHYSICS
·
2023
·
IF 4.6
Xia Zhao,Hong Hao,Haixia Pang,Min Jiang,Yanping Duan
Emulsifier-free polymerization was employed to prepare the submicron spherical PSA (the copolymer of styrene and acrylic acid), then SiO 2 was grown on the surface of the PSA by sol-gel method to form F–SiO 2 @PSA particles. It was found that when styrene: acrylic acid = 2.5:1 and tetraethyl orthosilicate : PSA was between 2.17:1 and 6.38:1, a perfect raspberry-like structure could be obtained. The coating based on F–SiO 2 @PSA particles exhibited contact angles of 167.3 ± 1.4°, 152.1 ± 1.5°,150.3 ± 1.6°, 150.9 ± 1.6°, 142.2 ± 1.7°, 143.7 ± 1.5° and 146.6 ± 1.9° to water, diiodomethane, soybean oil, rapeseed oil, hexadecane, kerosene, and waste engine oil , respectively. The F–SiO 2 @PSA coating could reduce the adsorption of protein by 90% compared with the control surface . It was observed that bacteria and platelets could hardly adhere to the coating surface after 24 h of E. coli culture and 3 h of platelet-rich plasma immersion. The anti-adhesion to proteins, platelets, and bacteria will give the coating a promising application in the medical field.
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JOURNAL OF HAZARDOUS MATERIALS
·
2023
·
IF 13.6
Xiaolan Zhang,Shufang Xu,Zhimin Liu,Zhigang Xu,Qinpeng Shen,Shiyun Tang,Zhihua Liu,Xiaoxi Si
Bisphenol F (BPF) has evoked global attentions due to its ubiquity and detrimental effects. Herein, a flexible molecularly imprinted fiber library was firstly proposed for the metabolic analysis of BPF in aquatic ecosystems . The library includes flexible single fibers and fiber arrays to precisely identify BPF and its metabolites with a wide range of polarities. Compared to commercial polyacrylate , the performance increased 11.56–570.98-fold. The adsorption capacity and the Log K ow value were positively related. These arrays were used for the acquisition of environmental metabolomics data from aquatic ecosystems. In-depth data analysis showed that risk quotient was lower than 0.76, and bioaccumulation factor was lower than 2000 L/kg. Distribution concentration of BPF and its metabolites changed seasonally, and accumulation in sediment was much larger than that in surface water and hydrobionts. The risk is gradually increasing in sediment, but it does not reach high risk. The likelihood of bioaccumulation of parent compounds was greater than its metabolites. The library can be used in the metabolic diagnosis of pollutants with a broad range of polarities, providing a new method to acquire data for further ecological risk assessment , and offering a revolutionary strategy for environmental metabolomics investigation in aquatic ecosystems.
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MATERIALS CHEMISTRY AND PHYSICS
·
2023
·
IF 4.6
Yatao Pan,Guangjing Hou,Xiaojuan Wang,Xia Ran,Pingan Liu,Lijun Guo
Developing novel inhibitors for the fibrillization of amyloid peptides and understanding the relevant assembly processes are essential for biomedical and biomaterial sciences. Herein, we have synthesized and characterized the nitrogen and fluorine co-doped graphene quantum dots (N, F-GQDs), and investigated their inhibition of the fibrillization of Amyloid-beta peptide (1–42) (Aβ 42 ) by monitoring the assembly morphologies in the Aβ 42 /N, F-GQDs systems. Our results indicate that the N, F-GQDs functionalized with multiple surface groups effectively inhibits the fibrillization of amyloid Aβ 42 . The strong adsorption of Aβ 42 on N, F-GQDs significantly reduces the generation of β-sheet structures and the cytotoxicity of Aβ 42 /N, F-GQDs aggregates. Accordingly, a morphological evolution from the long fibrils of Aβ 42 to the spherical particles and unique closed-loop structures of Aβ 42 /N, F-GQDs have been captured. A possible interpretation for the observed phenomena in the presence of N, F-GQDs has been proposed by combining the different inhibition effects of other GQDs on the fibrillization of Aβ 42 and the results from various control experiments. Moreover, the inhibition activity of N, F-GQDs demonstrates good adaptability to resist the fluctuation of pH value and the interference of divalent metal ions , facilitating their practical applications in the future.
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FOOD CHEMISTRY
·
2018
·
IF 4.946
Nan Wang,Huijuan Chai,Xuelin Dong,Qian Zhou,Lihua Zhu
Iron(III) ethylenediaminetetraacetate (Fe(III)EDTA) is widely used in iron fortification for reducing iron deficiency, and its determination is urgently needed. The present work developed a fluorescent method to straightforwardly determine Fe(III)EDTA by using photoluminescent carbon dots (C-dots) with the aid of F − ions as the masking agent of free Fe 3+ ions. In the presence of F − ions, only Fe(III)EDTA selectively quenched the photoluminescence of C-dots, and both Fe 3+ and Fe 2+ as well as other carboxylic acids have no effect on the emission of C-dots. The sensing mechanism was attributed to the ligand-tailored electron transfer process from C-dots to Fe 3+ . Under optimum conditions, this method showed a linear calibration plot over the Fe(III)EDTA range of 1.0–200 μmol L −1 and a detection limit of 0.4 μmol L −1 . The proposed method was successfully applied to determine Fe(III)EDTA in real samples with acceptable recoveries of spikes (95%−110%) and repeatability (RSD, 4.2%−9.5%).
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Wenfeng Han,Jinchao Wang,Lulu Chen,Luteng Yang,Shucheng Wang,Miao Xi,Haodong Tang,Wucan Liu,Weiyu Song,Jianjun Zhang,Ying Li,Huazhang Liu
Trifluoromethane is one of the most potent and stable greenhouse gases with global warming potential of 14,800 times higher than CO 2 (100-year time horizon). At present, it is destroyed by incineration or plasma at temperatures above 1200 K. For the first time, this work report that CHF 3 can be reverted to HCFC-22 via the intermolecular Cl/F exchange reaction of CHF 3 with CHCl 3 over AlF 3 catalyst under moderate conditions. As CHF 3 is produced during the manufacture of HCFC-22 via the fluorination of CHCl 3 in liquid phase, no additional feedstock and products are involved for the treatment of CHF 3 in this proposed process. At 593 K and atmospheric pressure, CHF 3 conversion levels of about 18%–20% are achieved and no significant deactivation is observed following time on stream of 100 h. In addition, the catalytic reaction mechanism is proposed. According to the experiments and DFT calculation, the intermolecular Cl/F exchange reaction of CHF 3 with CHCl 3 is mainly initiated by the breakage of C Cl. The present work provides a potential resource utilization route for the treatment of CHF 3 and other hydrofluorocarbons (HFCs).
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危险品化学品经营许可证（带存储）