APPLIED CATALYSIS A-GENERAL
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2020
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IF 5.006
Haodong Duan,Xiaolei Xu,Kangwei Leng,Ge Guo,Qing Yu,Xinjin Li,Yuxi Han,Jun Gao,Zhongwei Wang
The characteristics of the reaction for the preparation of dichlorophenylphosphine (DCPP) via benzene and PCl 3 in the presence of AlCl 3 were studied. Some unique characteristics were observed when a catalytic amount of AlCl 3 was used. Namely, more than one mole of DCPP was obtained per mole AlCl 3 , the reaction solution was layered, and DCPP could be directly separated. Our mechanistic study showed that benzene reacted with PCl 3 to form DCPP-AlCl 3 , and DCPP-AlCl 3 dissociated into DCPP and AlCl 3 , continuing to catalyze this reaction. This resulted in the high catalytic efficiency of AlCl 3 . The layering of the reaction solution was caused by the immiscibility of DCPP-AlCl 3 with the raw materials, greatly facilitating the dissociation process of DCPP-AlCl 3 . The formation of diphenylphosphorus chloride (DPC) was due to a continuous Friedel-Crafts reaction between DCPP and benzene. DPC cooperated with AlCl 3 to form the stable coordination compound DPC-AlCl 3 that did not dissociate and was responsible for the deactivation of AlCl 3 .
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ELECTROCHIMICA ACTA
·
2020
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IF 6.215
Huiying Ouyang,Weifeng Li,Yumei Long
Since dopamine (DA) is one of the central neurotransmitters and plays an important role in the human metabolism, its accurate detection is crucial for the diagnosis of DA-linked diseases. Herein, we demonstrated a novel electrochemical sensor for DA detection based on carbon-doped hexagonal boron nitrogen (C-hBN). C-hBN was prepared via a thermal polymerization process using melamine borate as a precursor. The successful C-doping was evidenced by fourier transform infrared (FTIR), photoluminescent (PL) and x-ray photoelectron spectroscopy (XPS). The carbon-doping can increase reactive sites and facilitate electrons transfer in h-BN, which was confirmed by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The C-hBN modified glassy carbon electrode (C-hBN/GCE) exhibited the enhanced electrocatalytic activity toward DA redox, whose CV peak current is 2.8 and 4.3 times higher than those of pure h-BN modified and bare GCEs, respectively. Based on CV method, the C-hBN/GCE presented a low detection limit of 5.8 nM (S/ N = 3) and a sensitivity of 2037 µA•mM•cm −2 . The linear response ranges were over the DA concentrations of 0.01–40 µM and 40–300 µM, respectively. In addition, the sensor was applied to detect DA in real samples including human serum and urine, and satisfactory results were achieved. The results suggested that the defect-engineered h-BN holds great potential for the development of electroanalytical devices with high-performance.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2021
·Vol. 32
·期 17
·21858-21868
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IF 2.478
Wang Jinmao,Yan Hong,Long Yumei,Li Weifeng
In this work, a series of h -BN/ α -SnWO 4 (BN/SW) nanocomposites with different h -BN concentrations (0.3–1.0 wt%) were prepared through a hydrothermal method. The composition, structure and morphology of BN/SW nanocomposites were systematically investigated. The formation of BN/SW heterojunction was evidenced by Fourier transform infrared (FTIR), X-ray photoelectron spectroscopy (XPS) and high-resolution transmission electron microscopy (HRTEM). The BN/SW composites showed plate-to-plate structure consisting α -SnWO 4 and h -BN nanoplates. The optical and photoelectrochemical studies revealed that the decorating of h -BN can significantly facilitate the separation of the photo-created charge carries due to the formation of heterostructure. As a result, BN/SW hetero-structure exhibited the superior photocatalytic performance under visible light, which was confirmed by the photo-degradation of methyl orange (MO) and tetracycline (TC). Especially, the BN/SW-0.5 sample has the best rate constant of 0.0323 min −1 , which is 4.6 times larger than that of α -SnWO 4 . Based on trapping experiment, the h + radical was identified as the dominant reactive species, and ·O 2 − and ·OH also made contribution to the photocatalysis. In addition, the photocatalytic enhancement mechanism of BN/SW heterojunction was proposed. This study shed light on the roles of h -BN in the design of photocatalysts with high-performance.
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Jove-Journal of Visualized Experiments
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2018
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IF 1.184
Ya-Min Du,Shen-Li Zheng,Li Liu,Josef Voglmeir,Gabriel Yedid
In recent years, the carbohydrate moieties of plants have received considerable attention, as they are a potential source of cross-reactive, allergy-provoking immune responses. In addition, carbohydrate structures also play a critical role in plant metabolism. Here, we present a simple and rapid method for preparing and analyzing N-glycans from different cultivars of radish (Raphanus sativus) using an N-glycanase specific for the release of plant-derived carbohydrate structures. To achieve this, crude trichloroacetic acid precipitates of radish homogenates were treated with PNGase H+, and labeled using 2-aminobenzamide as a fluorescent tag. The labeled N-glycan samples were subsequently analyzed by ultra performance liquid chromatography (UPLC) separation and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry for a detailed structural evaluation and to quantify relative abundancies of the radish-derived N-glycan structures. This protocol can also be used for the analysis of N-glycans from various other plant species, and may be useful for further investigation of the function and effects of N-glycans on human health.
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高影响因子
EUROPEAN JOURNAL OF PHARMACOLOGY
·
2017
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IF 2.896
Cheng-yuan Li,Mei Su,Yun-yi Yan,Lin Zhou,Lu-yao Ao,Wei-rong Fang,Yun-man Li
1-(5-(1H-indol-5-yl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (KFP-H008)，a novel and potent potassium-competitive acid blocker for the treatment of acid secretion related diseases, has not been reported previously. In this study, we demonstrated that KFP-H008 inhibits basal acid secretion, 2-deoxy- D -glucose- (2DG-) stimulated gastric acid secretion in rats. KFP-H008 blocked histamine-stimulated acid secretion in rats and heidenhain pouch dogs and reversed acid output in isolated gastric perfusion under histamine stimulation. In all the animal experiments, KFP-H008 exerted a more effective, potent and longer-lasting inhibitory action in comparison with lansoprazole , a proton pump inhibitor (PPI) commonly used in clinic. KFP-H008 inhibited H + -K + -ATPase activity both at pH 6.5 and pH 7.5, and was unaffected by pH. The inhibitory action was reversible and was achieved in a K + -competitive manner. Furthermore, KFP-H008 did not affect Na + -K + -ATPase activity, thus exhibiting high selectivity, which is different from PPIs. In all, KFP-H008, a novel potassium-competitive acid blocker, may provide new option for the patients with acid-related diseases and provide longer-lasting inhibitory action than drugs commonly used in clinical treatment.
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COMPOSITES SCIENCE AND TECHNOLOGY
·
2024
·
IF 8.3
Sijia Sun,Shuai Zhang,Mingzhu Pan
Intelligent fire warning system is a crucial protective equipment reduce fire hazards . A recent increasing concern is the development of sensitive fire warning materials that can be integrated with combustible materials to provide real-time alarms in the fire. However, current research on improving the sensitivity of fire warning sensors based on temperature-resistance response focuses on constructing continuous conductive networks. The effect of the heat transfer process is ignored, which limits the further improvement of alarm sensitivity. Here, we developed a strategy to improve thermal conductivity . Based on the chitosan (CS) conductive network in Ti 3 O 5 -based fire sensing system, aminated 2D h-BN nanosheets with high temperature resistance and ultrahigh in-plane thermal conductivity were further introduced. The h-BN improves the thermal conductivity of the fire warning coating from 1.43 W/m·K to 2.29 W/m·K. Intelligent fire warning sensors with ultra-sensitivity (1.16 s), low response temperature (170 °C), duration time (12 min) and durability (100 cycles) were successfully prepared by improving thermal conductivity to rapidly transfer heat to Ti 3 O 5 , which leads to a rapid decrease in resistance as the core mechanism. This work proposed an ingenious strategy for the construction of high fire safety and thermal conduction fireproof coatings, which revealed enticing prospects in the field of intelligent coatings.
研究领域:
材料科学
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传感技术
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JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION
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2018
·Vol. 33
·期 5
·1176-1185
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IF 0.524
Lu Guosen,Deng Min,Mo Liwu
C3S pastes containing 0%, 5%, 10%, and 15% nano-SiO2 mixed with de-ionized water and alkali solutions were prepared. When C3S was completely hydrated, the pastes were ground into powders with a particle size less than 80 μm. Adsorption and desorption characteristics of alkali ions adsorbed by C 3 S-nano SiO 2 pastes mixed with de-ionized water immersed in alkali solutions and those in C 3 S-nano SiO 2 pastes mixed with alkali solutions, were investigated. Meawhile, the adsorption mechanisms of alkali ions were discussed. Results showed that the contents of alkali ions adsorbed by C 3 S-nano SiO 2 pastes mixed with de-ionized water increased with increasing substitution levels of nano-SiO 2 and/or the initial alkali concentrations. In C 3 S-nano SiO 2 pastes mixed with de-ionized water, each paste was characterized by having a fixed alkali-adsorption capacity that was essentially independent of alkali concentration. No obvious difference between the adsorption capacity of a given paste for K + and Na + was observed. Adsorption of alkali ions in the pastes is considered to be caused by surface force which is related to the BET specific surface area of the paste, and charge compensation of C-S-H gel, mainly by electrostatic interactions. In C 3 S-nano SiO 2 pastes mixed with alkali solutions, alkali ions may enter the structure of C-S-H gel to replace a part of Ca 2+ in the interlayer. This assumption is supported by the structural characterization of C-S-H gel using 29 Si MAS NMR.
研究领域:
材料科学
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化学工程
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JOURNAL OF ORGANIC CHEMISTRY
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2023
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IF 3.6
Jianbo Tang,Junhua Kong,Hui Xu,Zhi-Jiang Jiang,Yifan She,Jianfei Bai,Bencan Tang,Jia Chen,Zhanghua Gao,Kun Gao
Silver-catalyzed deuteration of nitroaromatics has been achieved using D2O as the deuterium source. Distinct from the well-established directing group-guided hydrogen-isotope exchange, this protocol showed an interesting deuteration pattern, where considerable deuterium accumulation was observed around the aromatic rings. Controlling experiments suggested that the deuteration was initiated by a silver-promoted C–H activation. Therefore, a tentative two-stage deuteration mechanism involving aryl-silver species was proposed to explain the deuteration on meta- and para-positions.
研究领域:
有机化学
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同位素化学
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CONSTRUCTION AND BUILDING MATERIALS
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2024
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IF 7.4
Yuyang Zhao,Zhaoyang Sun,Gang Qiao,Xu Fang,Binmeng Chen
Given that CO 2 chamber and high inner pressure are needed in the traditional carbonation curing, we propose an in-situ internal carbonation by mesoporous silica nanoparticles (MSN) to tackle the challenge, leveraging its high specific surface area. In this study, MSN was functionalized with γ-aminopropyl triethoxy silane (MSN-amine), followed by reacting with CO 2 (CO 2 carrier) and mixing with alite paste. Phase transformation and nucleation behavior were investigated by conducting comparative in-situ carbonation of alite paste, utilizing MSN-amine in two configurations: one adsorbing CO 2 (MSN-amine-AC) and the other desorbing CO 2 (MSN-amine-DC). Results indicated that semi-crystalline C-S-H is produced in alite paste containing MSN-amine-DC (Ap-MSN-DC) through pozzolanic reaction while amorphous calcium carbonate (ACC) is generated in alite paste with MSN-amine-AC (Ap-MSN-AC) via in-situ carbonation, both of which promote the early reaction of alite. Additionally, low Ca/Si ratio calcium silicate hydrate (C-S-H) with negative electric potential developed as MSN-amine-DC gradually eroded, collapsed, and chemically transformed into reactive sites. Conversely, the ACC generated in MSN-amine-AC blocks the mesopores, inhibits the pozzolanic reaction and preserves the silica skeleton. Subsequently, calcite is crystallized via the dissolved ACC and embedded itself on the surface of C-S-H with positive electric potential, turning to nucleation sites physically. To conclude, the proposed in-situ internal carbonation models for MSN-amine-modified alite paste offer insights into microstructural evolution.
研究领域:
材料科学
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化学工程
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RSC Advances
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2024
·Vol. 14
·期 10
·6502-6507
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IF 3.9
Jiaqi Wang,Kaihong Liu,Jingjing Zhao,Xiuping Li,Bolin Yin,Bo Jiang,Hexing Li
Direct CO2 hydrogenation to value-added chemicals is a promising path toward realizing the “carbon-neutral” goal. However, controlling the selectivity of CO2 hydrogenation toward desired products (e.g., CO and CH4) using non-precious metal-based catalysts is important but challenging. It is imperative to explore catalysts with high activity and stability. Herein, boron-doped cobalt nanoparticles supported on H-ZSM-5 were devised for CO2 hydrogenation to produce CO in a gas–solid flow system. Our results demonstrate that boron doping not only increases the CO2 adsorption capability of the catalyst but also optimizes the electronic state of Co for CO desorption during hydrogenation process. As a result, the boron-doped cobalt catalysts displayed an enhanced CO selectivity of 94.5% and a CO2 conversion rate of 45.6%, which is much higher than that of Co-ZSM-5 without boron doping. This study shows that the strategic design of metal borides is important for controlling the selectivity of desired products in the CO2 hydrogenation reaction.
研究领域:
催化化学
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材料科学
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环境科学
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INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 3.1
Dong Binbin,Hou Zong,Zheng Zhong,Xing Junpeng,Zhao Ningning,Liu Zhiqiang,Liu Shu
Ginseng polysaccharides have attracted research interest for their pharmacological value. In this study, the simplified combination of DEAE cellulose-52 ion-exchange column and ultrafiltration was designed to isolate a novel polysaccharide named GPA-G3-H from ginseng. The main components of GPA-G3-H were determined to be glucose, galacturonic acid, galactose and arabinose. The structure of GPA-G3-H was further comprehensively characterized by zeta potential analysis, nuclear magnetic resonance (NMR), X-ray diffraction (XRD) and gas chromatograph-mass spectrometer (GC–MS). GPA-G3-H existed in the semi-crystalline state, with its backbone predominantly composed of 1,4-Glcp and 1,3,6-Galp. Moreover, GPA-G3-H possessed high content of galactose and uronic acid, uniform molecular size, plentiful negative charge and the highly branched structure. The radical scavenging experiments showed GPA-G3-H had excellent antioxidant activity. In vitro studies further revealed that GPA-G3-H could attenuate insulin resistance by increasing PK and HK activity, suppressing G6Pase and PEPCK activity in IR-HepG2 cells. These findings indicate that GPA-G3-H holds significant promise as both an antioxidant and functional food ingredient.
研究领域:
药理学
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生物化学
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COMPOSITES PART B-ENGINEERING
·
2025
·
IF 14.2
Jihong Jiang,Han Wang,Junlin Lin,Zhiyong Liu,Laibo Li,Yali Li,Zongjin Li,Lingchao Lu,Yunjian Li,Zeyu Lu
Previous studies primarily considered TiO 2 as a nano-filler to accelerate cement hydration due to the nucleation site effect. However, hydroxyl free radicals (•OH), released from TiO 2 under UV irradiation, also exhibit great potential to accelerate cement hydration owing to their high nucleophilicity arising from unpaired electrons. This study is the first to reveal the accelerating mechanism of •OH generated by photoexcited nano-TiO 2 on cement hydration. Current experimental results indicated that 5.0 wt% addition of photoexcited nano-TiO 2 (under 6 h of UV irradiation during the early curing stage) improved the dissolution rate of tricalcium silicate (C 3 S) by 30 %, followed by a 35 % increase in the hydration degree of cement paste. More importantly, the polymerization degree and high-density content of C–S–H gels were also improved by 26 % and 13 %, accompanied by a 46 % reduction in porosity of the composites. All the aforementioned improvements were attributed to the presence of •OH generated by photoexcited nano-TiO 2 , which significantly accelerated cement hydration by accelerating C 3 S dissolution, facilitating faster nucleation and growth of C–S–H gels. In addition, the Density Functional Theory (DFT) calculations revealed that the accelerating effect of •OH on cement hydration may stem from the stronger interaction between •OH and the Ca ion on the C 3 S surface compared to the water molecule, and the increased surface nucleophilicity due to the dispersion of unpaired elections from •OH to all the O ions in the surface layer. These findings provide a high-efficiency approach to accelerate cement hydration by photoexcited nano-TiO 2 , thereby paving the way for the development of advanced and sustainable cement-based materials.
研究领域:
材料科学
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化学工程
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