COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
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IF 5.2
Caifu Yi,Tianzhong Yuan,Huining Xiao,Hao Ren,Huamin Zhai
Paper-based packaging materials have drawn increased attention under the rising awareness of environmental issues, whereas the barrier properties of paper are inadequate for food packaging. This study aimed to improve the barrier properties of paper by multi-coating method. Chitosan was coated as the first layer primarily to improve the oil resistance of the paper, whereas hydrophobic modified nanocellulose was applied as the second layer to render the paper water-repellent as well as to further enhance its oil resistance. Finally, zein was coated as the third layer to achieve the heat-sealing property of paper, and further enhance the water and oil resistance of paper. The obtained triple-layer paper had a high kit number of 12 and a low Cobb 60 value of 2.6 g/m 2 , and exhibited heat-sealing ability without any adhesive agent, which has a peel strength of 372.6 N/m. The triple layers also effectively improved the mechanical properties , and decreased the moisture and oxygen permeability of the paper substrate. Moreover, the triple-layer paper possesses good antibacterial activity and cytocompatibility. This study may provide inspiration for improving the barrier properties of food packaging paper and endowing it with heat-sealing property.
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FOOD HYDROCOLLOIDS
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2023
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IF 10.7
Xin Liu,Fang Xie,Jiaojao Zhou,Jiangling He,Zia-ud Din,Shuiyuan Cheng,Jie Cai
Food-grade compound-stabilized high-internal-phase Pickering emulsions (HIPEs) have received widespread attention in food industry and functional foods. However, challenges are still there regarding the inclusion of active substances and quickly processing molding for food manufacturing. Herein, we used zein , tannic acid (TA) and sodium alginate (SA) to synergistically increase the stability of HIPEs. Owing to electrostatic, hydrophobic and hydrogen-bond interactions among protein, polyphenol and polysaccharide , Zein-TA-SA composite particles-stabilized HIPEs (ZTS-HIPEs) exhibited good pH and ionic strength stability. The HIPEs could further be used to load and solubilize β-carotene, while significantly improved the retention of β-carotene in different environments. Simulated in vitro digestion experiments showed that the release rate of free fatty acids and bioaccessibility of β-carotene in HIPEs were significantly improved, indicating that HIPEs might achieve efficient delivery of β-carotene in the gastrointestinal environment. In addition, the ZTS-HIPEs could be 3D printed as food-grade inks due to their good rheological properties as the printed models showed good precision and stability. In summary, the ZTS-HIPEs prepared in this study could be used not only as an effective delivery carrier of β-carotene, but also as a potential ink for 3D printing. The research findings in this study are expected to provide novel insight on HIPEs for nutrition delivery systems and future food manufacturing.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Yue Zhuo,Yuehui Liang,Duoxia Xu,David Julian McClements,Suqing Wang,Qi Li,Yahong Han,Fuguo Liu,Shuai Chen
Zein-quercetagetin-chondroitin sulfate (Zein-Que-CS) composite nanoparticles with different compositions were successfully fabricated using a novel antisolvent co-precipitation method. The mean particle diameter (97.5 to 219.4 nm), negative surface potential (−29.9 to −51.1 mV), and turbidity (265 to 370 NTU) of suspensions of Zein-Que nanoparticles increased after the addition of CS. Electrostatic attraction, hydrogen bonding, and hydrophobic attraction were the main driving forces for the formation of the composite nanoparticles. The encapsulation efficiency and loading capacity of the quercetagetin within the Zein-Que-CS (100:10:30) nanoparticles were 91.6 % and 6.1 %, respectively. The photostability and thermal stability of the encapsulated quercetagetin were 3.4- and 3.2- fold higher than that of the free form. The nanoparticles had good resistance to sedimentation and exhibited slow-release properties under simulated gastrointestinal conditions. The Zein-Que-CS nanoparticles developed in this study may therefore be useful for the encapsulation, protection, and delivery of quercetagetin.
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JOURNAL OF NANOBIOTECHNOLOGY
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2023
·Vol. 21
·期 1
·1-25
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IF 10.2
Yan Haozhao,Hao Li,Chen Huayao,Zhou Xinhua,Ji Hongbing,Zhou Hongjun
Background There is a serious global problem of salinization of arable land, causing large reduction in world food production. Use of plant hormones is an effective way to reduce damage caused to crops and salt stress.Results In this study, PEI-EDA was modified with AM-zein and grafted with plant hormone SA (AM-zein-SA) and used as a nano-pesticide carrier to load emamectin benzoate (EB). The use of AM-zein-SA as a nano-pesticide carrier could reduce the damage caused by salt stress to crops. The structure of AM-zein-SA was characterized by FTIR, UV, fluorescence, Raman, and 1H NMR spectroscopic techniques. AM-zein-SA could effectively improve the resistance of EB to ultraviolet radiations, resistance of cucumber to salt stress, and the absorption of EB by plants. The experimental results showed that AM-zein-SA could effectively improve the anti-UV property of EB by 0.88 fold. When treated with 120 mmol NaCl, the germination rate of cucumber seeds under salt stress increased by 0.93 fold in presence of 6.25 mg/L carrier concentration. The POD and SOD activities increased by 0.50 and 1.21 fold, whereas the content of MDA decreased by 0.23 fold. In conclusion, AM-zein-SA nano-pesticide carrier could be used to improve the salt resistance of crops and the adhesion of pesticides to leaves.Conclusion AM-zein-SA, without undergoing any changes in its insecticidal activity, could simultaneously improve the salt stress resistance and salt stress germination rate of cucumber, reduce growth inhibition due to stress under high-concentration salt, and had a good effect on crops. In addition, EB@AM-zein-SA obviously improved the upward transmission rate of EB, as compared with EB. In this study, SA was grafted onto zein-based nano-pesticide carrier, which provided a green strategy to control plant diseases, insects, and pests while reducing salt stress on crops in saline-alkali soil.Graphical Abstract
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FOOD CHEMISTRY
·
2023
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IF 8.8
Yufan Shi,Shuang Rong,Tingxian Guo,Ruyi Zhang,Duoxia Xu,Yahong Han,Fuguo Liu,Jiaqi Su,Hongxin Xu,Shuai Chen
The main purpose of this study was to prepare zein-chondroitin sulfate (ZC) nanocomplex by anti-solvent co-precipitation, and to encapsulate, protect and controlled-release curcumin. As the proportion of chondroitin sulfate (CS) increased, the particle size, turbidity and zeta-potential of the ZC nanocomplexes all increased. When the mass ratio of zein and CS was 10:3, the ZC nanocomplex had small particle size (129 nm) and low polydispersity index (0.3). According to FTIR, FS, CD and XRD results, zein and CS were tightly bound by electrostatic attraction, hydrophobic effect and hydrogen bonding. The ZC nanocomplex was designed to encapsulate curcumin with high encapsulation efficiency (94.7%) and loading capacity (3.8%), and also enhanced the resistance of curcumin to light and thermal degradation by 2.9 and 2.4 times. It also exhibited controlled release capability during simulated gastrointestinal digestion. These results suggested the ZC nanocomplex is a good delivery vehicle to facilitate the application of curcumin.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Qin Ouyang,Yanna Rong,Baoning Wang,Waqas Ahmad,Shuangshuang Liu,Quansheng Chen
Pickled frequently contains nitrosodimethylamine (NDMA), a mutagenic and carcinogenic substance that is dangerous for the general public's health. This study reports on the fabrication of a fluorescent biosensor using zein film and aptamer functionalized upconversion nanoparticles (UCNPs) for on-site monitoring of NDMA in meat. UCNPs were first prepared followed by aptamer binding and mixing with zein film, which was further conjugated with cDNA of dabcyl modified at 5′. The fluorescence resonance energy transfer (FRET) mechanism between the UCNPs and dabcyl was exploited. The fluorescence signals of the zein film recovered when NDMA was present because it was selectively collected by the particular aptamer and damaged the cDNA structure. The designed functionalized zein film was used for on-site and portable determination of NDMA with a lower limit of detection of 0.017 ng/mL, and possessed a satisfactory recovery ranging from 95.8% to 100.2% with no significant difference compared with the GC–MS method.
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LWT-FOOD SCIENCE AND TECHNOLOGY
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2023
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IF 6
Renjie Li,Jin Chen,Huihui Li,Zhuangwei Zhang,Hongjin Tang
Zein-gum arabic-tea polyphenols ternary complex nanoparticles have been developed for the encapsulation of luteolin, but there are still shortages existed in their particle properties such as encapsulation efficiency, stability, and release ability of luteolin. To improve their performance, calcium ions (Ca 2+ ) were employed as a cross-linking stabilizer to investigate their effects on particle properties and functional performance. Particle parameters, physicochemical stability, antioxidant activity, and in vitro simulated gastrointestinal digestion were evaluated based on zetasizer measurement and multi-spectral methods, which were analyzed using Graphpad Prism v6.0.2. As a result, low concentrations of Ca 2+ induced the formation of smaller and more compact nanoparticles with improved luteolin encapsulation efficiency, while higher concentrations had the opposite effect. Hydrophobic, electrostatic, and hydrogen bonding interactions were found to be responsible for nanoparticle assembly and stability with Ca 2+ incorporation. Appropriate amounts of Ca 2+ promoted the physicochemical stability of the nanoparticles under different conditions such as pH, salt ion concentration, temperature, and storage time. Additionally, low levels of Ca 2+ strengthened the antioxidant activity of the nanoparticles and improved sustained release of luteolin under in vitro gastrointestinal conditions. These findings suggest that zein-gum arabic-tea polyphenols nanoparticles assembled with Ca 2+ have potential applications as a delivery system for bioactive substances.
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npj Science of Food
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2023
·Vol. 7
·期 1
·1-10
·
IF 6.4
Qiu Chao,Zhang Zhiheng,Li Xiaojing,Sang Shangyuan,McClements David Julian,Chen Long,Long Jie,Jiao Aiquan,Xu Xueming,Jin Zhengyu
In this study, composite nanoparticles consisting of zein and hydroxypropyl beta-cyclodextrin were prepared using a combined antisolvent co-precipitation/electrostatic interaction method. The effects of calcium ion concentration on the stability of the composite nanoparticles containing both curcumin and quercetin were investigated. Moreover, the stability and bioactivity of the quercetin and curcumin were characterized before and after encapsulation. Fluorescence spectroscopy, Fourier Transform infrared spectroscopy, and X-ray diffraction analyses indicated that electrostatic interactions, hydrogen bonding, and hydrophobic interactions were the main driving forces for the formation of the composite nanoparticles. The addition of calcium ions promoted crosslinking of the proteins and affected the stability of the protein–cyclodextrin composite particles through electrostatic screening and binding effects. The addition of calcium ions to the composite particles improved the encapsulation efficiency, antioxidant activity, and stability of the curcumin and quercetin. However, there was an optimum calcium ion concentration (2.0 mM) that provided the best encapsulation and protective effects on the nutraceuticals. The calcium crosslinked composite particles were shown to maintain good stability under different pH and simulated gastrointestinal digestion conditions. These results suggest that zein–cyclodextrin composite nanoparticles may be useful plant-based colloidal delivery systems for hydrophobic bio-active agents.
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INDUSTRIAL CROPS AND PRODUCTS
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2022
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IF 6.449
Wenquan Huang,Shiyuan Liu,Zhiqiang Li,Yingying Liu,Qiuling Xie,Yanbin Jiang
The past decade has witnessed rapid development in zein-based drug delivery systems . However, the lack of a deep understanding of self-assembly and co-self-assembly between drug and zein has limited its application. In this work, α and β-zein, the main ingredients of zein, were separated and the different self-assembly behaviour was investigated, respectively. In ethanol solution, α-zein shows uncontrollable self-assembly and explosive nucleation. The nano-mechanical properties investigated by AFM show that α-zein nanoparticles self-assembled in the ethanol possessed a higher adhesion force (99.45 ± 6.90 nN), which explains its uncontrollable self-assembly. After loading with paclitaxel (PTX), Young’s modulus of α-zein had significantly reduced from 525.57 ± 53.82–95.35 ± 20.98 MPa, which implies that the PTX-α-zein nanoparticle has a loose structure. The interaction between drug and carrier was studied using a fluorescence quenching experiment, and the mathematical model was established. The result shows that the main driving force for interaction between PTX and α-zein is the hydrophobic force, while interaction between PTX and β-zein is hydrogen bonding and Van der Waals forces. The negative ΔG value indicates that the binging between PTX and α-zein or β-zein is a spontaneous process although the nature of the interaction is somewhat different. An in vitro cytotoxicity study shows that the different self-assembly behaviour resulted in different cell viability . Finally, a possible self-assembly mechanism of α and β-zein was proposed. It is anticipated that a fundamental understanding of self-assembly between drug and α or β-zein will provide an important foundation for its application in biological and material fields.
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Journal of Functional Foods
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2021
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IF 4.451
Sitong Ge,Rui Jia,Qi Li,Wei Liu,Meihong Liu,Dan Cai,Mingzhu Zheng,Huimin Liu,Jingsheng Liu
The objective of this study was to explore the physicochemical stability and in vitro digestibility of astaxanthin (AST)-loaded Pickering emulsions stabilized by zein and Adzuki bean seed coat polyphenol (ABSCP) covalent nanoparticles. Compared to zein-alone stabilized Pickering emulsion (ZE), ABSCP fabrication improved the Pickering emulsion (ZAE) against the ionic strength and high-temperature treatment. Furthermore, the ratio of AST remaining in ZAE after exposure to high levels of UV light irradiation was higher than 90%. Due to the change in electrostatic repulsion during in vitro digestion, droplet size, zeta potential, and microstructure of ZAE changed. More importantly, the bioaccessibility of AST reached up to 58.56% ± 0.89% and 55.66% ± 1.48% for ZE and ZAE, respectively. The results indicate that ZAE may be an effective delivery system for AST or other hydrophobic bioactive compounds. This study may contribute to the protection and delivery of AST and the development of novel functional foods.
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JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
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2023
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IF 4.1
Qiuying Li,Wenxuan Zhou,Xinrui Yu,Fangchao Cui,Xiqian Tan,Tong Sun,Jianrong Li
BACKGROUND In order to develop effective active packaging films for tuna preservation, zein/gelatin (ZG) composite nanofiber films loaded with ε-polylysine (PL) and gallic acid (GA) were first prepared by electrospun method. The morphology, structure, thermal stability, hydrophobicity, antibacterial and antioxidant properties of the films and application in tuna during 4°C storages were investigated. RESULTS PL reduced the average diameter of ZG fibers, while GA increased it. PL/GA/ZG film possessed well-distributed fiber morphology with an average diameter of 810 ± 150 nm. Fourier transform infrared spectroscopy and X-ray diffraction results showed the physical loading of PL and GA in ZG film with unchanged main chemical bonds and crystal structure. Both the addition of PL and GA reduced hydrophobicity of the ZG film, while the PL/GA/ZG film is still hydrophobic. GA enhanced thermal stability and contributed to antioxidant activity of PL/GA/ZG film. PL and GA synergetic enhanced that antibacterial activity of ZG film against Shewanella putrefaciens . PL combined with GA is more suitable for modifying ZG film than GA alone. Moreover, PL/GA/ZG film effectively inhibited total viable count, total volatile base nitrogen, fat oxidation and texture deterioration of tuna fillets at 4°C storage, and could extend the shelf life by 3 d. CONCLUSIONS PL/GA/ZG nanofiber film have shown promising potential application in the preservation of aquatic products as a new antibacterial and antioxidant food packaging. This article is protected by copyright. All rights reserved.
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Materials Today Advances
·
2021
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IF 7.579
Yaowen Liu,Siying Li,Wenting Lan,Md Alomgir Hossen,Wen Qin,Kangju Lee
In this study, poly (ε-caprolactone) (PCL)/zein/Ag nanoparticle (AgNP) fibrous membranes were prepared by ultrasonication-assisted electrospinning. The effects of the AgNP content and ultrasonication time on the membrane morphology, chemical structure, biodegradability, mechanical properties, antibacterial/antiviral activity, and air filtration performance were studied. The best-performing membrane (AgNP content = 1% (w/v), sonication time = 30 min) exhibited a bead-on-string morphology, an air permeability of 93.6 ± 1.5 mm s −1 , and the Escherichia coli and Staphylococcus aureus removal efficiencies of 98.1 ± 1.2% and 97.4 ± 2.5%, respectively. In an experiment with E. coli phage, the above-mentioned membrane exhibited a 97.1 ± 2.1% virus removal efficiency after 60 min. The high performance of this bead-on-string membrane for air filtration was ascribed to the low packing density due to the presence of open interconnected beaded airflow channels and small beads.
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危险品化学品经营许可证（带存储）