JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2019
·
IF 2.298
Yue Sun,Weisheng Zheng,Rajendra Prasad Singh,Li Chen
In the current work, poly(4-vinylpyridine) (P4VP) was grafted on a macroporous polystyrene resin via free-radical polymerization by using the pendent vinyl group. The grafting conditions such as swelling agent, initiator concentration, reaction temperature, and amount of 4-vinylpyridine (4VP) monomer were optimized, and three resins with different 4VP monomer amounts (SC-1, SC-2, and SC-3) were chosen as adsorbents. P4VP-grafted resins were characterized by scanning electron microscopy, N2 sorption/desorption isotherms, Fourier transform infrared, and X-ray photoelectron spectroscopy. The sorption properties of 2-naphthalenesulfonic acid (NSA) on three resins were comparatively investigated. The experimental data revealed that the sorption process on three resins fitted well with the pseudo-second-order kinetics equation, and the equilibrium isotherms were in good agreement with the Langmuir model. The NSA sorption onto resins was an endothermic and spontaneous process, and SC-3 loaded with NSA can be efficiently regenerated by NaOH and ethanol mixed solution after sorption. The maximum sorption capacities of three resins indicated that P4VP-grafted resins possess good sorption ability toward NSA.
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JOURNAL OF MATERIALS SCIENCE
·
2018
·Vol. 53
·期 22
·15487-15499
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IF 2.993
Yang Ming,Rao Richuan
In this work, nonmetallic S was doped into hierarchical Ni(OH) 2 hollow microspheres by ethanol solvothermal method using thiourea as sulfur source. Although the morphology of precursor Ni(OH) 2 is maintained, the surface states and pore properties had greatly changed after S doping. Using the as-prepared S-doped Ni(OH) 2 as adsorbents for the removal of Congo red (CR), the S-doped Ni(OH) 2 exhibited much better adsorption capacity compared with undoped Ni(OH) 2 . The adsorption behavior of both Ni(OH) 2 and S-doped Ni(OH) 2 followed the pseudo-second-order kinetic model and intraparticle diffusion model. The equilibrium data of Ni(OH) 2 could be better fitted by Langmuir model, while Freundlich model could be better used to describe the S-doped Ni(OH) 2 with a much larger adsorption capacity toward CR. The tuned microstructure and changed surface states of adsorbent after S doping may be responsible for the enhanced adsorption performance. Therefore, the doping of S species into hierarchical Ni(OH) 2 paves a new way to tune the microstructure and surface states of Ni-based materials.
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Journal of Cleaner Production
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2018
·
IF 5.651
Guo Lin,Shixing Wang,Libo Zhang,Tu Hu,Jinhui Peng,Song Cheng,Likang Fu,C. Srinivasakannan
A bioadsorbent was synthesized by modifying corn bract with 2-aminothiazole for the selective recovery of gold. Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) were used to characterize the bioadsorbent with the aim of understanding the mechanism of adsorption. Adsorption isotherms and kinetics data were determined and modeled. The adsorption capacity of Au(III) was 1668 mg/g, much higher than the values reported in the literature due to the ion exchange and chelation between the amino/thiol groups and Au(III). Additionally, the effect of pH and other ions on the Au(III) adsorption capacity were assessed. The adsorption isotherm was found to be consistent with the Langmuir isotherm model, and the kinetic was consistent with the pseudo-second-order kinetic model . Further regeneration and cyclic adsorption tests were performed to ensure the effectiveness of the bioadsorbent in commercial applications.
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BIOMEDICINE & PHARMACOTHERAPY
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2018
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IF 3.457
YingHui Zhang,Bing Wang,Feng Guo,ZhiZhen Li,GuiJun Qin
Diabetic nephropathy is one of the manifestations of systemic microangiopathy in diabetes. Hesperetin , a natural flavanone glycoside compound in citrus fruits, has been demonstrated to exert hypoglycemic effects and protect kidney in experimental diabetic animals. The current study was aimed to investigate the mechanisms underlying the hypoglycemic effects of hesperetin in high-fat/streptozocin (STZ)–induced diabetic nephropathy. The results showed that mice in whom hesperetin was administered for 4 weeks attenuated the increased fasting blood glucose and impaired glucose tolerance ability that was observed in high-fat/STZ mice. In addition, we found that hesperetin ameliorated the abnormalities of biochemical parameters in serum, liver, and kidney of mice with diabetic nephropathy. Hesperetin also rescued the irregular distortions in glomerular basement membrane and expanded mesangial regions. Moreover, hesperetin repaired the function of podocyte by increasing renal nephrin expression and decreasing renal alpha-smooth muscle actin expression. Furthermore, hesperetin inhibited the expression of transforming growth factor-β1 (TGF-β1) and its downstream effectors integrin-linked kinase (ILK) and Akt. In conclusion, our study implies that hesperetin produced protective effects in diabetic nephropathy possibly by suppressing TGF-β1-ILK-Akt signaling.
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PubMed
高影响因子
Food & Function
·
2019
·Vol. 10
·期 8
·5215-5227
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IF 3.241
Yufeng Chen,Fan Xue,Guobin Xia,Zhenlei Zhao,Chun Chen,Yunhong Li,Ying Zhang
7,8-Dihydroxyflavone (7,8-DHF), as a high-affinity TrkB receptor agonist, has been extensively explored in many human disorders involving brain-derived neurotrophic factor (BDNF) such as Alzheimer's disease, Parkinson's disease, depression, and obesity. However, to date, the transepithelial transport mechanisms of 7,8-DHF in the intestines remain unclear. The aim of our work was to quantify and to characterize in vitro transport of naturally occurring 7,8-DHF distinguished by its physicochemical and pharmacological properties. We discussed the transport mechanisms of 7,8-DHF using the Caco-2 cell model to determine the bi-directional permeability with different environmental factors (time, concentration, pH, metabolic inhibitors etc.). The influx and efflux characteristics of 7,8-DHF were also clarified. 7,8-DHF was poorly transported across Caco-2 cell monolayers by mainly passive diffusion via a transcellular pathway and not a paracellular pathway. The transport of 7,8-DHF was time and concentration-dependent in both the apical (AP) to basolateral (BL) side and the reverse direction. Interestingly, decreasing the pH from 7.4 to 6.0 markedly enhanced 7,8-DHF transport. It is noteworthy that 7,8-DHF transport was strongly inhibited by metabolic inhibitors and was highly dependent on temperature. The efflux ratio (ER) values at different concentrations were all above 1.5, indicating the existence of the efflux transporter. We found that breast cancer resistance protein (BCRP) was not involved in 7,8-DHF secretion and that the transport mechanism of 7,8-DHF was passive transport with an active efflux mediated by P-glycoprotein (P-gp) and multidrug resistance associated proteins (MRPs), particularly MRP 2. Moreover, the use of various influx transporter inhibitors in Caco-2 cells showed that organic cation transporters (OCTs) and organic anion-transporting polypeptides (OATPs) participated in 7,8-DHF transport. Taken together, the elucidated transport characteristics of 7,8-DHF provide useful information for designing novel and efficient delivery systems and avoiding food–food or food–drug interactions.
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JOURNAL OF CHEMICAL THERMODYNAMICS
·
2019
·
IF 2.29
Lemeng Wang,Xiangfeng Tian,Dong Fu,Xiaoqian Du,Junhong Ye
Experimental data of CO 2 absorption capacity for high concentrated 1-dimethylamino-2-propanol (DMA2P)–monoethanolamine (MEA) aqueous blends are presented under atmospheric pressure in a temperature range of 303.2–323.2 K, at different mass fractions of DMA2P (30 wt%–50 wt%) and MEA (5 wt%–15 wt%). The mass fraction and temperature dependences of the absorption capacity are illustrated. The addition of small amount of MEA into DMA2P aqueous solution leads to an obvious increase in the absorption rate of CO 2 . However, the absorption rate increases not so significantly when w MEA is of high value. Moreover, the temperature affects the absorption rate not so significantly as compared to solution concentration. The CO 2 absorption heat of DMA2P-MEA based on the Gibbs-Helmholtz equation was found to be −55.0 kJ/mol. Besides, the viscosities of both CO 2 -unloaded and CO 2 -loaded aqueous solutions were measured and modeled in a temperature range of 303.2–323.2 K, and in atmospheric pressure. The effects of temperature, composition and CO 2 loading on viscosities were demonstrated. The Weiland equation gave a good prediction with an average relative deviation of 2.42%. Moreover, the activation energy ( E a) was estimated based on the viscosity.
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FOOD AND AGRICULTURAL IMMUNOLOGY
·
2018
·
IF 2.568
Fengyin Liu,Zijian Chen,Yudong Shen,Yuanming Sun,Jinyi Yang,Hong Wang,Hongtao Lei,Zhenlin Xu
Immunoassay direct for 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ), the metabolite of furaltadone, based on a specific antibody was usually unavailable due to its small molecule weight. In this work, a hapten with a double bond and an active carboxyl group was designed and then conjugated to peptide dendrimer to obtain novel multiple haptens. The haptens and multiple haptens were coupled to bovine serum albumin as immunogens. Polyclonal antibodies showed binding to free AMOZ in a heterologous competitive indirect enzyme-linked immunosorbent assay were obtained. The assay showed IC50 (half maximal inhibitory concentration) of 4.1 μg/kg and limit of detection of 0.2 μg/kg for AMOZ. Recoveries of AMOZ from grass carp were tested from 83.1% to 117.0%, with the coefficient of variation below 12%. As no laborious derivatisation procedure was employed, the proposed assay should be useful for the screening of AMOZ for a large number of samples.
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ELECTROCHIMICA ACTA
·
2017
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IF 4.798
Hongmei Chen,Xiaoqin Sun,Xiaoxiang Xu
Here we report two Ruddlesden-Popper type ferrite perovskites (SrO)(LaFeO 3 ) n (n = 1 and 2) which demonstrate p-type semiconductivity. Their crystal structure, optical absorption and other physicochemical properties have been systematically explored. Our results show that both ferrites crystallize in tetragonal symmetry with structural lamination along c axis. Efficient photocatalytic hydrogen production has been achieved for both samples under full range and visible light illumination. Better performance is noticed for LaSrFeO 4 with apparent quantum efficiency approaches 0.31% and 0.19% under full range and visible light illumination, respectively. The p-type semiconductivity is verified by their cathodic photocurrent as well as negative Mott-Schottky slop during Photoelectrochemical measurement. The relative lower activity for La 2 SrFe 2 O 7 compared to LaSrFeO 4 is likely due to its higher defect concentration which facilitates charge recombination. Both compounds exhibit anisotropic phenomenon for charge migrations according to theoretical calculations. Their p-type semiconductivity, strong visible light absorption, chemical inertness and high abundance of constituent elements signify promising applications in the field of solar energy conversion and optoelectronics.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2017
·
IF 3.671
Jinsong Zhang,Youzhi Zhou,Ke Liu,Jianlin Chu,Yewei Zhang,Bingfang He
A novel nucleoside 2′-deoxyribosyltransferase ( Lh NDT) from Lactobacillus hilgardii ZJS01 was cloned and expressed in Escherichia coli BL21 (DE3). The amino acid sequence of Lh NDT displayed the highest identity of 26% to other reported NDTs. Lh NDT was a monomer as revealed by gel filtration chromatography with or without addition of Ca 2+ in elution buffer. This enzyme showed a high activity and stability over a broad pH range and was sensitive to temperature. With the addition of 15 mM Ca 2+ , the thermostability of Lh NDT was greatly promoted by 63 times and 46 times at 30 °C and 35 °C, respectively. With the use of 2′-deoxyuridine as sugar donor at an economic molar ratio of 1:1, 5-aza-2′-deoxycytidine (46%) and 5-fluoro-2′- deoxycytidine (58%) were efficiently synthesized from 5-azacytosine and 5-fluorocytosine, respectively, by Lh NDT for 2 h.
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高影响因子
Journal of Materials Chemistry B
·
2017
·Vol. 5
·期 44
·8770-8779
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IF 4.543
Jiachen Sun,Yanxia Zhang,Bin Li,Yong Gu,Liang Chen
Stimulating the adhesion and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is crucial for the scaffold materials used in bone tissue engineering. In this study, a silk fibroin (SF)/nano-hydroxyapatite (nHAp) scaffold was prepared, embedded with SF microspheres containing bone morphogenetic protein-2 (BMP-2) and surface-modified through chemical conjugation with the type I collagen-mimetic peptide GFOGER. Surface-bound GFOGER and sustained BMP-2 release promoted the adhesion and osteogenic differentiation, respectively, of BMSCs. Our results indicated that this system released low doses of BMP-2 in a sustained manner, thereby avoiding cost and safety problems. The biological responses to this scaffold were investigated both in vitro and in vivo. Our results indicated that the synergistic effect of GFOGER and BMP-2 promoted the adhesion and osteogenic differentiation of BMSCs, thus leading to complete bone bridging of rat cranial defects after 12 weeks of implantation. This system might provide a powerful platform for treating bone defects and for bone tissue engineering.
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高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2017
·
IF 3.012
Waqar Uddin,Gang Hu,Lin Hu,Yanyang Hu,Zhaohui Fang,Rooh Ullah,Xuanxuan Sun,Yu Zhang,Jimei Song
A new technique for identification of two aromatic isomers between 2-hydroxy benzoic acid (2-HBA) and 3-hydroxy benzoic acid (3-HBA) was finalized by using their perturbation effects on a Briggs-Rauscher (BR) oscillator, in which a tetraazamacrocyclic Ni complex, [NiL](ClO 4 ) 2 was used as catalyst. The ligand L in the complex is 5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradeca-4,11-diene. By putting two isomers into this BR oscillator, the 2-HBA caused a decrease in potential (amplitudes), an increase in the period of oscillation (∆ T) and a decrease in number of the oscillation cycle (n) while no influences of 3-HBA on the BR oscillation were observed. Hence, these two aromatic isomers of hydroxy benzoic acid (HBA) were identified in the range from 1 × 10 − 5 to 2.2 × 10 − 4 mol L − 1 . Reaction mechanism of BR has been proposed with reference to the NF and FCA models. An explanation of perturbation mechanism for the BR is that, only 2-HBA reacted with IO 2 • to form 1,2-quinone while the 3-HBA didn't.
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JOURNAL OF PLANT PATHOLOGY
·
2024
·
IF 2.2
Reymick Okwong Oketch,Duan Bin,Feng Zhao,Zhang Yong Hua,Ouyang Qiuli,Kaaya Archileo N.,Tao Nengguo
Management of Penicillium digitatum requires use of highly effective fungicides that are not prone to drug resistance and are safe to humans and the environment. This study examined the fungicidal potential of combinations of cuminaldehyde (CA) + trans-2-hexen-1-al (TH) and CA + Citral. Both CA + TH and CA + Citral exhibited enhanced fungitoxicity against P. digitatum than CA, citral or TH alone. The minimum inhibitory concentration (MIC) of CA + Citral consisted of 0.13 ml/L CA and 0.3 ml/L citral, representing a synergistic interaction. MIC of CA + TH consisted of 0.12 ml/L CA and 0.15 ml/L TH, representing an additive interaction. The minimum fungicidal concentration (MFC) of CA + Citral and of CA + TH consisted of 0.26 ml/L CA and 0.6 ml/L citral, and 0.18 ml/L CA and 0.24 ml/L TH, respectively. 10×MFC CA + Citral in Tween-80 (WCI) delayed onset of hyphal growth in fruits inoculated with P. digitatum to day 5 compared to day 4 in the 10×MFC CA + TH in Tween-80 (WCT) treatment, and day 3 for the control samples. Daily green mold disease incidence and disease severity were much lower in WCI and WCT treatments than in the 10×MFC CA in Tween-80 (WCA) treatment and in control samples. Our results show that WCI was much fungitoxic against P. digitatum than WCT and WCA, its effect being comparable to that of imazalil. Additionally, at 25 ± 2 °C and 85–90% relative humidity, both WCI and WCT markedly preserved fruit quality by day 6 of treatment. WCI and WCT are thus, safe, cheap and highly effective alternatives to chemical fungicides being used to control postharvest green mold in citrus fruits.
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