Nature Communications
·
2025
·
IF 15.7
Lan Zhineng,Yang Yingying,Huang Hao,Du Shuxian,Zhang Qiang,Wang Zhiwei,Jiang Tongtong,Sun Changxu,Qu Shujie,Li Liang,Yan Luyao,Cui Peng,Li Meicheng
The perovskite solar cells (PSCs) achieve notable advances in stability under humidity, light, and heat stress. However, PSCs are still susceptible to reverse-bias degradation, mainly due to the inevitable iodide ions migration. Herein, we reveal the irreversible cross-layer migration of iodide ion (I - ) within PSCs under reverse bias, which contributes to the device performance failure. Further, we innovatively construct an electrostatic repulsion with I - at the perovskite interface, which can inhibit I - cross-layer migration under reverse bias in a nonbonding manner. Besides, the TFMS capable of blocking the hole injection can reduce the interface I - oxidation under reverse bias. The modified PSCs deliver efficiencies of 25.80% with TiO 2 as the electron transport layer (ETL) and 26.21% (certification of 26.09%) with SnO 2 as the ETL. More importantly, the device exhibit an enhanced reverse-bias stability by maintaining >80% of initial efficiency after 25 bias aging cycles (0 V/−1 V/0 V, each stage lasts for 12 hours). Our work provides a route to inhibit ion migration in PSCs and other perovskite-based devices through a novel interaction of electrostatic repulsion.
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Human Cell
·
2025
·Vol. 39
·期 1
·19
·
IF 3.1
Zhu Linwen,Li Ni,Shi Huoshun,Song Jie,Fang Zhongjie,Shen Qinbo,Zhu Xiuying,Dan Yanggang,Shao Guofeng,Sun Lebo
Circular RNAs (circRNAs) are involved in cardiovascular disease development and progression. We identified has_circ_0000437 from three pairs of clinical samples using a circRNA microarray and predicted the has_circ_0000437 sponge let-7f-5p using bioinformatics. We expanded the sample to confirm the expression, correlation, and diagnostic value of has_circ_0000437, let-7f-5p and RAS-like proto-oncogene B (RALB) in rheumatic valvular heart disease (RVHD). The effects of has_circ_0000437 and let-7f-5p on biological function were observed in hVICs cells. To explore the molecular pathogenesis of has_circ_0000437 in the RVHD process, the target binding protein RAS-like proto-oncogene B (RALB) of has_circ_0000437 was obtained using label-free mass spectrometry and parallel reaction monitoring. The influence of the has_circ_0000437/let-7f-5p/RALB axis on the expression of mitogen-activated protein kinase (MAPK)-related proteins in the inflammatory signaling pathway predicted by Kyoto Encyclopedia of Genes and Genomes (KEGG) during RVHD was measured using Western blotting. We found that let-7f-5p was at low expression and negatively correlated with has_circ_0000437, which had a diagnostic value with an area under the curve of 0.998 after the combined diagnosis. Has_circ_0000437 and let-7f-5p had binding sites, and let-7f-5p alleviated the effect of has_circ_0000437 on the proliferation, migration, and cycle progression of hVICs. The inhibitory effect of has_circ_0000437 on hVICs apoptosis was diminished. Mechanism studies showed that has_circ_0000437 promotes the MAPK pathway through has_circ_0000437/let-7f-5p/RALB axis. These findings suggest that the has_circ_0000437/let-7f-5p/RALB axis promotes the MAPK pathway, proliferation, migration, and cycle progression in RVHD, inhibiting the apoptosis process, thereby promoting RVHD development. This pathway may suggest a target for RVHD diagnosis and treatment.
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FOOD SCIENCE AND BIOTECHNOLOGY
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2025
·
IF 3.1
Song Yang,Li Tingting,Zhang Xinyi,Mou Yanping,Wu Caie,Fan Gongjian,Li Xiaojing,Zhou Dandan
This study optimized the enzymatic production of isomalto-oligosaccharides (IMOs) from ginkgo starch and evaluated their functional properties for food and prebiotic applications. Various liquefaction parameters were systematically optimized via response surface methodology to enhance ginkgo-derived IMO (G-IMO) synthesis. Optimal liquefaction conditions were determined as pH 6.0, 94 °C, 21% substrate concentration, 21 U/g α-amylase, and 29-min reaction time. G-IMO was purified using 24-h yeast fermentation, increasing the total content of four key functional components from 30.12 to 54.00%. Physicochemical analyses showed G-IMO had a smaller particle size and molecular weight than commercial IMOs, with comparable solubility, hygroscopicity, and water retention. Prebiotic activity assays confirmed G-IMO promoted probiotic growth similarly to commercial IMOs. This study demonstrates that ginkgo starch is a viable raw material for producing IMOs with functional properties equivalent to commercial products, offering an economical approach for food additive and prebiotic health product development.
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International Journal of Minerals Metallurgy and Materials
·
2025
·Vol. 32
·期 12
·3072-3085
·
IF 7.2
Zhang Qian,Liu Bo,An Changcong,Li Qiong,Liu Jiling,Wei Siyu,Fan Jiaxing,Sun Zhe,Zhang Dichuan,Pulatov Bakhtiyor
The effect of heavy metals on the properties and hydration of blast furnace slag–cement composites (BFS-CC) remain unclear. In this study, two BFS-CC (denoted as DBFS-CC and WBFS-CC) were prepared by dry and wet grinding of BFS, respectively. The effect of Cu(II) on BFS-CC’s properties and hydration was investigated by adding representative copper contaminants (CuO, CuCl 2 , and CuS) to the composites. Adding 1.0wt% CuO and 0.5wt% CuS increased the 3-d compressive strength of DBFS-CC by 14.9% and 5.7%, respectively, but suppressed the 3-d strength of WBFS-CC. This trend reversed at 28-d curing, where adding 1.5wt% CuO, 2.0wt% CuCl 2 , and 1.5wt% CuS enhanced the compressive strength of WBFS-CC by 23.4%, 6.2%, and 13.6%, respectively, but adversely affected the strength of DBFS-CC. For 28-d hydration, adding CuCl 2 decreased the hydration degree of DBFS-CC but enhanced that of WBFS-CC. Adding CuO promoted the hydration degree of both composites, while adding CuS exhibited inhibitory effects. DBFS-CC immobilized CuCl 2 better due to a higher hydration degree, while WBFS-CC immobilized CuO and CuS better due to having finer unhydrated BFS particles and a denser matrix. This study not only focuses on the Cu(II) immobilization effect but also reveals the differential effects of Cu(II) species on the hydration process, providing novel insights into heavy metal interactions in BFS-CC systems and their safe disposal.
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Nature Communications
·
2025
·
IF 15.7
Hu Xuewen,Zhou Tiantian,Cui Tiansi,Du Yuanjiao,Song Chunyu,Chang Weiping,Xiong Juan,Qin Jichao,Deng Lin,Ji Wei-Ke
Sigma Non-Opioid Intracellular Receptor 1 (SigmaR1) is a member of the sigma family of receptors that interacts with a variety of psychotomimetic drugs and is involved in a wide range of cellular and physiological functions. Despite its increasing importance in human physiology and disease, the subcellular localization of SigmaR1 and its molecular function remain poorly defined. Using endogenous tagging and cell fractionation, we show that SigmaR1 is a type II integral ER membrane protein that is specifically enriched at ER sheets. A short region at the N-terminus of SigmaR1 promotes its ER-sheet localization. Importantly, our biochemical studies demonstrate that SigmaR1 directly interacts with components of the translocon complex including TRAPα and Nicalin. In addition, we found that a β-barrel at the C-terminal of SigmaR1 binds phosphatidylcholine (PC), and the binding of PC strengthens the association of SigmaR1 with the translocon complex. SigmaR1 knockout systematically impaired cellular protein and lipid homeostasis, resulting in accumulation of lipid droplets in hepatocytes. Collectively, we propose that SigmaR1 is an auxiliary translocon factor that binds lipids to regulate protein and lipid droplet homeostasis, which may underlie the broad and vital roles of SigmaR1 in physiology and disease.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2025
·Vol. 37
·期 1
·7
·
IF 2.8
Meng Weili,Dong Chao,Zhou Jiafeng,Cheng Hongwei,Wang Qingqing
Exploring eco-friendly, low-cost, and chemically stable electron acceptor material is of great significance for the hybrid polymer-based solar cells (HPSCs). In this paper, Manganese tetroxide (Mn 3 O 4 ) nanoparticles with a unique tetragonal and hexagonal lamellar structure (4–8 nm) were successfully synthesized by solvothermal method, exhibiting an optical bandgap of 2.39 eV. The as-prepared Mn 3 O 4 nanoparticles were used as electron acceptors for HPSCs blended with a conjugated polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene](MEH-PPV) , and delivered a power conversion efficiency ( η ) of 0.73%. Notably, decorating Mn 3 O 4 with the reduced graphene oxide (rGO) to form rGO–Mn 3 O 4 composites significantly improved device efficiency by 38.4%, reaching a η of 1.01%. This enhancement is attributed to the extended electron lifetime facilitated by the formation of rGO–Mn 3 O 4 composite, which provides abundant exciton separation interfaces, thereby promoting efficient exciton separation and charge transfer. These findings offer a new strategy for designing high-performance, sustainable electron acceptor materials for HPSCs.
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WOOD SCIENCE AND TECHNOLOGY
·
2025
·Vol. 60
·期 1
·17
·
IF 3
Han Yuchen,Zhong Wei,Zheng Jie,Wu Jianfeng,Jiang Bo,Jin Yongcan,Wu Wenjuan
Lignin possesses the advantages of high carbon content and abundant functional groups, making it suitable as a supercapacitor electrode material. However, the microstructure of lignin-derived electrode materials obtained through traditional methods limits the effective utilization of energy storage capacity, resulting in a significant loss of electrochemical efficiency. Doping with heteroatoms in lignin-derived carbon can enhance its electrochemical performance and is a promising method for performance improvement. We employed a green and universal approach to design lignin-derived carbon materials by covalently grafting phosphorus source (DOPO) and nitrogen source (HDI) onto the lignin macromolecular framework through organic synthesis. Using modified lignin (NPAL) as a precursor, we achieved simultaneous carbonization and activation through a one-pot method. The nitrogen and phosphorus doping synergistically enhances pseudocapacitance activity (redox reactions), optimizes the hierarchical pore structure (increasing the specific surface area to 1756.79 m 2 /g), and improves charge transfer kinetics (reducing charge transfer resistance to 6.63 Ω). This results in a high specific capacitance (276.3 F/g @ 0.25 A/g, an increase of 275.56% compared to undoped materials), high energy density (12.5 Wh/kg), and cycling stability (capacity retention of 92.5% after 10,000 cycles), indicating a promising application prospect.
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JOURNAL OF MATERIALS SCIENCE
·
2025
·
IF 3.9
Feng Xu,Xiong Yuxiang,Zhou Changjian,Lin Xinying,Li Yuanyuan,Hu Fei,Hu Huawen
The design of efficient and durable electrocatalysts for acidic oxygen evolution remains a critical challenge. Recent advances have demonstrated that synergistic microstructure engineering and electrical resistance modulation can dramatically enhance the intrinsic activity and stability of acidic OER electrocatalysts. In this work, we systematically investigate the impact of fabrication methodology on the structure, morphology, and electrocatalytic properties of Co 3 O 4 catalysts. Three representative techniques—ink-spraying, dip-coating, and drop-casting—were compared using a unified precursor and substrate framework. The ink-sprayed Co 3 O 4 catalyst exhibits superior performance, achieving an overpotential of 386 mV at 100 mA·cm −2 , a Tafel slope of 51.5 mV·dec −1 , and exceptional durability over 165 h at 10 mA·cm −2 in 0.5 M H 2 SO 4 . X-ray photoelectron spectroscopy (XPS) reveals a notable increase in the Co 2+ /Co 3+ ratio and oxygen-vacancy concentration after long-term operation, indicating surface reconstruction and enhanced redox flexibility. Notably, the relative contribution of the oxygen-vacancy (O V ) component increases from 20.9% in the pristine state to 28.2% after 24 h of OER operation. The uniform nanostructure, improved conductivity, and robust film adhesion endow the ink-sprayed electrode with both enhanced activity and stability, outperforming the dip-coated and drop-cast counterparts as well as most state-of-the-art Co-based OER catalysts reported in the literature. Furthermore, inductively coupled plasma mass spectrometry (ICP-MS) analysis confirms minimal metal leaching, highlighting the catalyst’s structural integrity and long-term stability. This work underscores the crucial role of fabrication methodology in tailoring catalytic performance and establishes ink-spraying as an efficient strategy for engineering high-performance Co 3 O 4 catalysts suitable for acidic water electrolysis applications. Graphical abstract
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Microsystems & Nanoengineering
·
2025
·Vol. 11
·期 1
·246
·
IF 9.9
Guo Chenfei,Liu Lin,Cai Zhengyang,Wang Yingyi,Guan Kejie,Sun Fuqin,Zhou Weifan,Gou Xiaoshuang,He Xiaoqian,Wang Xiaowei,Zhang Ting
Two-dimensional (2D) materials are intensively studied as promising materials for gas sensors owing to their large surface area and low working temperature. In this work, we report the synthesis of a layered SnS 2 single crystal by a chemical vapor deposition (CVD) approach for NO 2 sensing. By tuning the growth temperature, high-quality crystals with a lateral size over 3 mm are obtained in 30 min. The 2D SnS 2 sensor with optimized thickness (~15 nm) shows a low detection limit (2 ppb), a fast recovery time (66 s/1 ppm), and a high response (~4702% @ 1 ppm NO 2 ) at room temperature (RT) under UV illumination. An in-situ Kelvin probe force microscope is employed to reveal the high selectivity of SnS 2 through qualitative and semi-quantitative analysis of charge transfer behavior, including the directions and amount of charge transfer, upon exposure to different gases. In-situ Raman and first-principles density functional theory calculations further confirm the sensing mechanism toward NO 2 . Both experimental and theoretical results suggest that 2D SnS 2 holds promising potential as an RT NO₂ sensing material.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2025
·Vol. 36
·期 36
·2292
·
IF 2.8
Xiong Wanxing,Wang Jilin,Li Shaofei,Li Zhengde,Ji Yuchun,Long Fei,Yu Yuanlie
The creation of thermally conductive pathways in polymers is crucial for achieving high thermal conductivity in composites. In this study, a novel ultrafine and ultrathin-walled boron nitride hollow nanotube (BNNT) was employed to fabricate two types of 3D-BNNT/EP composites, 3D-BNNT/EP-p and 3D-BNNT/EP-f, prepared via powder hybrid compression molding and ice-templating methods, respectively. The experimental results show that the 3D-BNNT/EP-p composites exhibit high performance at high BNNT loading (55.87 wt%). The in-plane thermal conductivity reached 1.091 W/(m K), representing a 590% enhancement over pure epoxy resin (0.185 W/(m K)), while the T 60% decomposition temperature increased by 63 °C, indicating superior thermal conductivity and stability. Practical application tests reveal that this material can reduce the maximum operating temperature of LED devices by 11.3 °C, demonstrating its heat dissipation advantages. In contrast, the ice-templated composites showed higher filler efficiency at low BNNT loading (10.18 wt%), achieving an 89% improvement in in-plane thermal conductivity. However, their 3D network contained CMC-Na binder, leading to discontinuous thermal pathways and only a 24 °C improvement in thermal stability. Dielectric property measurements confirmed that both types of composites maintained the low-dielectric characteristics of the epoxy matrix, with the compression-molded samples exhibiting more stable dielectric loss behavior at high frequencies. Finite element simulations verified the thermal enhancement mechanism of 3D-BNNT networks and highlighted the impact of processing methods on performance. These findings provide both a theoretical foundation and practical guidance for the selection and design of high-performance thermal management materials in advanced electronic and optoelectronic devices.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 2
·68
·
IF 5.3
Guo Xing,Liu Yuanhang,Zhao Dong,Duan Qianqian,Sang Shengbo
African swine fever (ASF) is an acute hemorrhagic disease in pigs caused by the African swine fever virus (ASFV), which has a high mortality rate and brought great damage to global pig farming industry. At present, there is no effective treatment or vaccine to combat ASFV infection, so early detection of ASFV has become particularly important. Therefore, the PDMS/chitosan/MPMs composite film was proposed to detect ASFV P72. PDMS mixed with chitosan particles were used to provide biological modification sites for the ASFV P72 antibody, which simplified the functional modification process. The specific binding of antigen and antibody leads to the mechanical deformation of the composite film, which was observed through optical method to change the microsphere spacing. The polystyrene microsphere (PMs) spacing changes were acquired by simply measuring the diameters of the Debye ring diffracted by the PDMS/chitosan/PMs with a simple laser pointer. The conductive layer formed by AgNWs realize the transformation of biological signals to electrical signals. By conjugating PMs with Fe 3 O 4 nanoparticles (MPMs) and applying a magnetic field, a magnetic-stress-electric coupling system has been constructed, which amplifies the deformation of the composite film and enhances the sensitivity of the flexible film. The experimental results showed that the flexible film has wide linear range of 10 ng/mL–100 μg/mL, and the optimal detection limit (LOD) is 0.059 ng/mL, which was about one order of magnitude lower than that without magnetic field. In addition, the flexible film showed a good stability, specificity, and selectivity. Graphical
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npj Flexible Electronics
·
2025
·
IF 15.5
Li Mancheng,Zhang Wenjing,Lv Xinyang,Liang Xiaoci,Wang Mengye,Chen Chen,Liu Chuan,Han Songjia
Organic electrochemical transistors (OECTs), endued with processing and memory functionalities, present a remarkable potential for neuromorphic electronics. However, integrating processing and memory cores for neuromorphic systems is complicated by heterogeneous material compatibility and device architecture constraints. Here, we demonstrate a versatile regionally controlled ion-doping strategy for modulating the operational mode of OECTs between high-performance computing and non-volatile memory, without varying the materials or operating conditions. The key to this method is the use of inkjet-printed electrolytes with programmable 3D architectures, which can be precisely deposited onto the OECT channel, achieving a tunable thickness ranging from 100 nm to several tens of micrometers. By engineering the electrolyte’s spatial structure, we demonstrate two complementary OECT configurations: ion-rich OECTs with multilayer electrolytes achieve high stimulus-resolution capability of 1 ms for dynamic computation, and ion-deficient OECTs with single-layer electrolytes establish stable ion-trapping memristive states (300 s retention). Moreover, the integration of ion-rich and ion-deficient OECTs enables a neuromorphic circuit capable of simultaneous encoding and storage of alphanumeric information. This study presents a simple yet effective strategy that overcomes material compatibility constraints and simplifies circuit design, paving the way for highly integrated neuromorphic systems based on OECTs.
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危险品化学品经营许可证（带存储）