Plants-Basel
·
2025
·Vol. 14
·期 14
·2094
·
IF 4.1
Feixiong Zheng,Zhangting Xu,Xiaoji Deng,Xiaoyuan Wang,Yiming Sun,Xiaoxia Shen,Zhenming Yu
Flavonoids are key bioactive compounds in plants that play important defense roles against abiotic stress and are involved in plant growth and development. Methyl jasmonate (MeJA) is a significant growth regulator that promotes the accumulation of flavonoids in a variety of plants, but the effect of MeJA inHedera helixremains poorly understood. In the present study, the flavonoid content was significantly increased after MeJA treatment and peaked at 6 h post-treatment. A total of 31,931 genes were identified using transcriptome, and 6484 DEGs were identified at 6 h post-treatment. Through GO and KEGG enrichment analysis, it was shown that DEGs were primarily enriched in phenylpropanoid biosynthesis pathways. Based on the putative transcription factors derived from DEGs, growth-regulating factor (GRF), a transcription factor potentially linking MeJA signaling to flavonoid accumulation and participating in plant growth and stress responses, was further identified. A total of 20 Hh-GRFd genes were identified on the whole genome level and clustered into five phylogenetic groups with conserved subfamily characteristics. Abundant MeJA-responsive cis-elements were presented in the promoter regions ofHhGRF1-HhGRF20. They exhibited a tissue-specific expression variation, andHhGRF10was dominantly expressed in leaves ofH. helix. Notably,HhGRF10exhibited MeJA-induced expression that correlated temporally with flavonoid accumulation, suggesting thatHhGRF10might play a potential role in promoting flavonoid biosynthesis, and overexpression and knockout assay substantiated this conclusion. The finding provides the first transcriptome-wide resource for flavonoid biosynthesis inH. helixand identifies the candidate GRF-mediated regulator for flavonoid accumulation.
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TALANTA
·
2024
·
IF 5.6
Yanling Hao,Bin Huo,Fangyu Wang,Qilong Xie,Wenting Liang,Litao Jia,Heqin Guo,Yanbo Wu,Qiang Wang
In this study, tetrabutylammonium chloride (TBAC), tetrabutylammonium bromide (TBAB), and choline chloride (ChCl) were innovatively applied in the liquid-liquid microextraction (LLME) of bisphenol A (BPA) from edible oil by forming water-based deep eutectic solvent (WDES). The presence of water is not only used in the synthesis of WDES, but also modulates the viscosity of DES and improve its diffusion and mass transfer properties. Several crucial parameters affecting the extraction efficiency were examined, including the type and amount of WDES and the extraction time. The results indicated that TBAC-H 2 O (molar ratio 1: 5) WDES exhibited the best extraction ability, the optimal extractant dosage was 100 μL and the extraction time was 3 min. Under the optimized experimental conditions, the proposed method showed a low detection limit (0.2 ng mL −1 ), good linearity (R 2 = 0.997), precisions (RSDs ≤5.1 %) and was successfully employed to detect BPA in edible oil with excellent recoveries (90.6–102.6 %). The formation of the WDES was confirmed by 1 H NMR, differential scanning calorimetry (DSC). The extraction mechanism was explored through theoretical calculations and Attenuated Total Reflection Fourier Transform Infrared spectroscopy (ATR-FTIR) analysis. The results revealed that the separation of BPA by WDESs was primarily dominated by hydrogen bonds, and the hydrogen bond interaction between TBAC-BPA was stronger than that of TBAB-BPA and ChCl-BPA. This work provides a valuable reference for the determination of trace BPA in edible oils or similar samples in food safety monitoring and screening.
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IONICS
·
2025
·
IF 2.6
Wang Yuhang,Ren Zhiqi,Sun Jiaxiu,Li Xinze,Huang Bin,Yang Jianwen
In this work, the effect of potassium permanganate (KMnO 4 ) pre-oxidation treatment on the electrochemical properties of LiNi 0.83 Co 0.11 Mn 0.06 O 2 (NCM811) cathode materials was investigated. X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS) tests revealed that the pre-oxidation treatment promoted the oxidation of Ni 2+ to Ni 3+ and the formation of a stable Mn-rich surface. Electrochemical testing showed that the electrochemical performance of the NCM811 material pre-oxidized with an appropriate amount of KMnO 4 (811–3) was significantly improved at both ambient (25 ℃) and elevated temperatures (55 ℃) compared to the untreated sample. Additionally, the air stability of 811–3 was enhanced. Specifically, the pre-oxidation treatment increased the oxidation state of nickel, minimized side reactions with CO 2 and moisture in the air, and improved cycling stability, rate performance, and lithium-ion diffusion. It also resulted in a lower self-discharge rate, ensuring better long-term voltage retention. These results indicated that KMnO 4 pre-oxidation is an effective strategy for improving the electrochemical performance of NCM811 and has the potential for application to other Ni-rich cathode materials.
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MOLECULAR BIOLOGY REPORTS
·
2025
·Vol. 52
·期 1
·1-14
·
IF 2.8
Liang Chen,Guo Liping,Tian Xinyan,Mu Zhidan,Chen Mingyang,Hu Yarong,Su Juan
Objective By establishing a mouse model of hepatic ischemia–reperfusion injury (HIRI), to investigate the effects of cyclooxygenase-2 (COX-2) and endoplasmic reticulum stress (ERS) on HIRI and their interaction in HIRI. Methods C57BL/6J male mice were divided into four groups: Sham operation group (Sham group), hepatic ischemia–reperfusion (HIR) group, hepatic ischemia–reperfusion + Salubrinal (ER stress inhibitor) pretreatment group (HIR + Sal group), hepatic ischemia–reperfusion + NS398 (inhibitor of COX-2) pretreatment group (HIR + NS398 group). The levels of Aspartate transaminase (AST) and Alanine transaminase (ALT) in serum, the activity of Super Oxide Dismutase (SOD) and the content of malondialdehyde (MDA) in liver tissue were detected. The mRNA and protein expression of Glucose-regulated protein 78 (GRP78), C/EBP homologous protein (CHOP), phosphorylated eukaryotic translation initiation factor 2α (p-eIF2α) and COX-2/PTGS (Prostaglandin-endoperoxide synthase) in liver tissue were detected. The morphological changes and apoptosis of liver tissue were observed. Results Compared with the Sham group, the serum ALT and AST levels of the HIR group were increased, the SOD activity in the liver tissue was decreased, the MDA content and the expression of COX-2, p-eIF2α, GRP78 and CHOP protein were increased, and the staining results showed that hepatic sinusoidal congestion, a large number of hepatocyte death, inflammatory cell infiltration and apoptotic cells were significantly increased. The levels of ALT and AST decreased after Sal or NS398 pretreatment. SOD activity was increased, MDA content, COX-2, GRP78, CHOP mRNA and protein were decreased in liver tissue, and staining showed that liver tissue injury was improved. Conclusion In mice with HIR, COX-2 interacts with ERS to cause liver injury by regulating oxidative stress and apoptosis.
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DESALINATION
·
2025
·
IF 9.8
Zhongsen Yan,Xiaocui Chen,Qizhen Yang,Shuhui Zhou,Gongduan Fan,Haiqing Chang,Kaiqin Xu,Fangshu Qu
Although Janus membranes have shown excellent anti-wetting and fouling-resistant properties in membrane distillation (MD), the associated heat and mass transfer mechanisms remain insufficiently understood, particularly concerning the trade-off between fouling resistance and permeate flux. In this study, a Janus membrane was fabricated by depositing a polyamide (PA) layer onto a polyvinylidene fluoride (PVDF) substrate to form a PA/PVDF composite. To elucidate the mass transfer behavior, an enhanced computational fluid dynamics (CFD) model, considering the effects of membrane material and surface temperature on evaporation enthalpy, was developed to simulate MD performance using both PA/PVDF and pristine PVDF membranes. When assuming a constant evaporation enthalpy of free water (FW) (2.44 MJ·kg −1 ), the modeled and experimental fluxes matched closely for the PVDF membrane, while a flux deviation exceeding 10 % was observed for the PA/PVDF membrane. Accounting for the membrane-specific evaporation enthalpy reduced the deviation to 0.59 %, emphasizing its critical role in flux prediction. These results highlight the importance of incorporating membrane-dependent thermodynamic properties to improve MD modeling accuracy and guide the rational design of Janus membranes.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Xingdong Yang,Wan-yue Zhuang,Sen Zhang,Jie Zou,Aiguo Gu,Qi Wang,Jun-qin Qiao,Hong-zhen Lian
Nitrofurantoin (NFT) residue in animal-derived food poses a threat to human health. We proposed a novel strategy for NFT determination in feed and milk, which connected pretreatment technology to electrochemical detection. Cobalt nanoparticles encapsulated in nitrogen-doped carbon nanostructure with carbon nanotubes (Co/N-CNS-CNTs) were prepared for modifying magnetic electrodes. Meanwhile, magnetic reduced graphene oxide wrapped in phenyl-functionalized mesoporous silica (MG@mSiO 2 -Phe) was synthesized as magnetic solid-phase extraction (MSPE) adsorbent. The modified magnetic electrode can gather NFT-adsorbed MSPE materials and then detect NFT via differential pulse voltammetry (DPV) without elution and solution transfer procedures. Both analyte enrichment by MG@mSiO 2 -Phe and signal amplification by Co/N-CNS-CNTs synergistically improved detection sensitivity with slope of calibration curve and limit of detection of 1.365 μA (μmol L −1 ) −1 and 6 nmol L −1 , respectively. In actual samples, this method exhibits higher accuracy and reliability compared with direct DPV detection, and simpler operation process compared with liquid-chromatography method.
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PhotoniX
·
2025
·Vol. 6
·期 1
·1-17
·
IF 19.1
Qian Kun,Yang Hongyu,Li Jingzhou,Liang Dong,Li Jiaxi,Zhong Yichi,Xu Zhuhua,Zhang Jiahao,Yang Hanhuai,Liang Xizhe,Zhang Junping,Dong Hongxing,Zhang Long
Fluorescent antennas have emerged as promising alternatives to conventional lens modules in optical wireless communication (OWC) systems, offering an expanded field of view (FOV) by surpassing the étendue limit. However, their limited anti-interference performance in both time and frequency domains has constrained their widespread applications. Herein, we introduce a novel “laser antenna” that integrates stimulated emission from high-quality perovskite microlasers into the optical antenna design. Achieving a theoretical bandwidth of up to 36.2 GHz and a signal-to-noise ratio (SNR) of up to 40 dB, this laser antenna demonstrates strong anti-interference capabilities in the temporal domain. Furthermore, spectral analysis using amplitude shift keying (ASK) modulation reveals its distinct periodicity, tunability, and recoverability, enabling robust frequency selectivity even in the presence of interference. These findings establish the laser antenna’s potential to overcome critical limitations of conventional OWC systems, thereby paving the way for efficient, stable, and high-performance optical wireless links.
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Advanced Optical Materials
·
2025
·
IF 7.2
Wenbin Shi,Xiao Zhang,Ping Yang
Highly crystalline CsPbX 3 (X = Cl, Br, I) nanocrystals (NCs) are in situ grown in silicalite-1 zeolite framework by a high-temperature solid-state reaction at 600 °C without ligand addition. Subsequently, a CsPb 2 X 5 shell is hetero-epitaxial grown to form a CsPbX 3 /CsPb 2 X 5 core–shell structure. The resulting nanocomposites exhibit high photoluminescence quantum yields (PLQYs) and remarkable stability in a solid powder situation. The green-emitting (Br-based) and red-emitting (I-based) composites demonstrate nearly identical high PLQYs up to 82.9 and 83.2%, respectively, due to high crystallinity and core–shell structure. By easily adjusting halide compositions, the photoluminescence peak wavelengths of the NCs can be continuously tuned in the whole visible spectrum from 413 to 697 nm. These nanocomposites exhibit remarkable resistance to both photo-degradation under UV light irradiation and hydrolytic degradation in humid environments due to a hydrothermal treatment. The superior optoelectronic performance is ascribed to heterostructure formation and the protective confinement provided by the mesoporous silicalite-1 framework, which effectively passivates surface defects. Finally, the NCs are successfully applied to white light-emitting devices, achieving a chromaticity coordinate of (0.33, 0.32) and a correlated color temperature of 4793 K. This dual-passivation strategy, combining zeolite encapsulation and surface reconstruction, renders the nanocomposites particularly suitable for implementation in next-generation display technologies.
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Scientific Reports
·
2025
·Vol. 15
·期 1
·1-22
·
IF 3.9
Bai Guannan,Zhao Shaobo,Chen Lushan,Zhao Manli,Chen Wenhao
Osteosarcoma (OS) is the most common bone malignancy in children and adolescents. The 5-year survival rate is only approximately 20% in patients with metastatic and recurrent OS. There is an urgent need to explore novel therapeutic targets to improve the survivorship of OS patients. It has been reported that dysfunction of programmed cell death (PCD) plays an essential role in tumor malignancy. In this study, differentially expressed PCD genes (PCD-DEGs) in OS were identified. Functional enrichment and somatic mutation analysis were performed. Then we established a novel indicator, the cell death index (CDI), to predict therapeutic interventions, immunity responses, and prognosis concerning OS. The expression of PCD genes in osteosarcoma and normal tissues was determined by immunohistochemistry assays. A total of 265 PCD-DEGs were identified in OS, with 141 genes upregulated and 124 genes downregulated. After functional enrichment and somatic mutation analysis, a final PCD-related gene signature, involving the expression levels of CLTCL1, FADS2, and PLEKHF1, demonstrated significant predictive value. A nomogram including clinical characteristics and CDI was developed, which was verified to perform well. Further investigation showed CDI was strongly correlated with immunomodulators, tumor microenvironment, and drug sensitivity in OS. Immunohistochemistry assays illustrated that FADS2, CLTCL1, and PLEKHF1 were suppressed in OS tissues. Further experiments demonstrated that FADS2 inhibits migration and invasion of osteosarcoma cells, while FADS2 induces ferroptosis collaborating with Erastin in osteosarcoma cells. In conclusion, the PCD-related gene signature proposed in this study is a practical prognostic predictor for OS patients, which can make a notable difference in the assessment of clinical outcomes.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-14
·
IF 15.7
Wei Zhuoming,Ding Yunxuan,Shi Weili,Zhang Feiyang,Song Yuxiang,Cui Xin,Guo Yu,Sun Licheng,Jiang Qike,Zhang Biaobiao
The use of single-atom catalysts is an effective way to reduce the amount of iridium in proton exchange membrane water electrolysis (PEM-WE). However, conventional methods can only obtain surface-loaded single atoms or clusters which cannot meet the needs of high current density and stability. In this study, assisted by lanthanum-doping-induced ion exchange, we realize atomically anchoring iridium within the Co 3 O 4 lattice. The lattice anchored iridium in lanthanum-doped Co 3 O 4 exhibits higher atomic dispersion, a larger average coordination number, and an elevated oxidation state. This improvement stimulates the oxide path mechanism (OPM), resulting in enhanced activity (236 mV at 10 mA cm −2 ) and stability (1000 h at 10 mA cm −2 ). Impressively, our catalyst demonstrates notable performance in a PEM electrolyzer with an iridium mass loading of just 0.2 mg Ir cm −2 , achieving a low cell voltage of 1.61 V at 1.0 A cm −2 and maintaining stable operation for over 1000 h. This work presents an effective strategy for fabricating low-noble-metal-loading catalysts with enhanced efficiency for PEM-WE.
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Small
·
2025
·
IF 12.1
Jinyuan Zhang,Haifeng Liu,Jiajun Tian,Endong Hu,Xiujuan Gao,Haitao Hu,Zhengyou He,Kangli Wang,Kai Jiang,Hongwei Tao
Iron oxide (Fe 3 O 4 ) has attracted significant attention as a promising anode material for sodium-ion batteries (SIBs) due to its natural abundance, environmental benignity, and high theoretical capacity of 926 mA h g −1 . Nevertheless, its practical application is limited by intrinsic drawbacks, including low electrical conductivity, sluggish Na⁺ diffusion kinetics, and severe volume variation during cycling, leading to rapid capacity fading and poor rate capability. To address these issues, a novel Fe 3 O 4 /Fe@N-doped carbon (Fe 3 O 4 /Fe@CN) nanostructure is rationally designed, which integrates Fe 3 O 4 /Fe homogeneous heterojunctions with a uniform nitrogen-doped carbon shell. The built-in electric field at the Fe-Fe 3 O 4 interface promotes charge redistribution and accelerates electron/ion transport, while the N-doped carbon shell enhances electrical conductivity and buffers mechanical stress during sodiation/desodiation processes. Benefiting from this synergistic structure, the Fe 3 O 4 /Fe@CN anode delivers a high reversible capacity of 336.9 mA h g −1 at 0.1 A g −1 , excellent rate capability with 244.7 mA h g −1 at 2 A g −1 , and remarkable cycling stability, retaining 76.4% capacity after 500 cycles. Furthermore, a full cell assembled with a Na 3 V 2 (PO 4 ) 3 cathode exhibits a high energy density of 112.67 Wh·kg −1 at 51.42 W·kg −1 and outstanding cycling performance. This study offers a versatile strategy to unlock the potential of Fe 3 O 4 for high-performance SIB anodes through heterojunction and interfacial engineering.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2025
·
IF 6.2
Chengqi Zhang,Ying Wang,Ziyun He,Aoran Wang,Zikuo Li,Xuheng Gao,Haoxue Xia,Wende Liu,Guangfei Tang
Fusarium graminearum is a preeminent fungal pathogen exacting a heavy toll on global crop production. Fludioxonil, a highly effective broad-spectrum fungicide, has been extensively deployed to mitigate the devastation wrought by F. graminearum. Nevertheless, the molecular mechanisms of fludioxonil resistance in this pathogen remain largely enigmatic. In this study, we identify a novel point mutation (L837F) in FgOs1 (osmosensor-like histidine kinase), which is located in the HIS_KIN (histidine kinase) domain. Biological assays revealed that the FgOs1L837F mutation reduced the ability of F. graminearum to adapt to low-temperature stress, osmotic stress, and metal ion stress and also decreased its pathogenicity. Additionally, this mutation did not confer cross-resistance to the fungicides phenamacril, tebuconazole, and carbendazim. To facilitate field monitoring, we employed allele-specific PCR (AS-PCR) to detect FgOs1L837F point mutation in F. graminearum. This study offers crucial support for fungal disease control and crop protection.
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危险品化学品经营许可证（带存储）