Discover Food
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2025
·Vol. 5
·期 1
·1-15
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IF 3.7
Tian Zhen,Jin Huaizhou,Shang Xiaoxiao,Ma Qifei,Wang Weihong,Jin Shangzhong
The long-term stability of Pickering emulsions is crucial for their application in food systems. This study aimed to evaluate the stability degradation of oil-in-water (O/W) Pickering emulsions stabilized by whey protein isolate (WPI) and chitosan (CS), and to assess their applicability in reduced-fat mayonnaise formulations. Optical tweezers were employed to quantify the interaction forces between emulsion droplets during storage, in combination with microstructural observation and ζ-potential analysis. It was found that the O/W emulsion prepared with a 50% aqueous phase volume fraction maintained a stable droplet size over the storage period without significant changes. The ζ-potential decreased from 79.16 mV to 53.62 mV, while the maximum droplet contact force gradually decreased from 69 pN to 37 pN by day 45. By day 60, droplet coalescence was observed. Compared with traditional rice bran oil mayonnaise, the mayonnaise formulated using this Pickering emulsion exhibited superior mechanical stability and resistance to destabilization. In particular, the formulation with a Pickering emulsion-to-egg yolk volume ratio of 4:1 showed the best mechanical performance, with the droplet contact force gradually decreasing from 68 pN on day 0 to 62 pN on day 20. This study provides a rapid method for evaluating the stability of food systems, offering potential applications in the food industry.
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JOURNAL OF POLYMERS AND THE ENVIRONMENT
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2025
·
IF 5
Li Shuo,Xu Tongan,Deng Ming,Jia Ruyan,Djouonkep Lesly Dasilva Wandji
As sustainable polymer development gains urgency, vanillin, a lignin-derived renewable compound, has emerged as a promising aromatic building block. Capitalizing on phenyl structure, a novel biphenyl diester monomer (DEBM) was prepared from bio-sourced methyl vanillate. Subsequently, via melt polymerization DEBM along with phenol ether-based diols (hydroquinone bis(2-hydroxyethyl)ether (HQEE) and 1,3-bis(2-hydroxyethoxy)benzene (HBE)) and aliphatic diacids (succinic acid and adipic acid), afforded a series of ternary aromatic-aliphatic copolyesters (P 1 –P 4 ). The chemical structures were characterized using Fourier transform infrared (FT-IR) and nuclear magnetic resonance ( 1 H NMR) spectroscopy, molecular weight via gel permeation chromatography (GPC), thermal transitions and stability through differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and thermo-mechanical properties assessed by dynamic mechanical analysis (DMA) and tensile testing. From the results, the copolyesters were semi-crystalline in nature, with weight-average molecular weights ( M w ) ranging from 3.55 to 4.9 × 10 4 g/mol and polydispersity (PDI) within 1.58–2.13. The glass transition temperatures ( T g ) varied between 57.5 and 77.1 °C, melting point ( T m ) from 166.5 to 190.5 °C, and initial decomposition temperatures ( T d, 5% ) within 370.3–389.5 °C, highlighting the satisfactory thermal stability of the copolyesters. Tensile testing demonstrated robust mechanical strength (42–47 MPa) along with elongation at break (284–316%), outperforming conventional polyesters and comparable to poly(ethylene terephthalate) (PET). Furthermore, hydrolytic degradation under varying pH (7 and 10) over 16 weeks revealed significantly advanced decomposition rates at pH 10 compared to pH 7, owing to rapid hydrolysis of ester and ether functionality, resulting in modest weight loss between 2.9 and 4.5%. By integrating flexible aliphatic diacid segments with varying aromatic components, one can tune the aromaticity and physicochemical properties of copolyesters, offering a sustainable alternative to petroleum-derived counterparts. These copolyesters could potentially become of great interest to industrial automobiles, specifically friction plates, while significantly addressing ecological concerns related to material decomposition after their end of life.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-31
·
IF 15.7
Fan Mengke,Liu Chunyu,Zhang Yueyao,Zhang Jinlei,Lu Yang,Su Kun,Tian Pengfei,Zhou Yabin,Zhang Liyan,Gao Xianda,Li Honglong,Li Shuaijie,Du Ping,Li Xian,Chen Wei,Cui Xu,Pan Haobo
Osteosarcoma (OS), with a high tendency for recurrence and metastasis, is associated with severe impairment of bone regeneration. The inherent temperature-sensitive property of tumors positions magnetic hyperthermia (MH) as an increasingly significant area in non-pharmacological cancer treatments. However, the temperature threshold for tumor ablation often causes tissue damage and bone homeostasis imbalance. Therefore, development of moderate MH for OS, capable of achieving tumor ablation while concurrently restoring bone homeostasis, offers significant potential for addressing this challenge. This study integrates magnetothermal nanoparticles with defined temperature thresholds and borosilicate bioactive glass (BSG) to create an injectable magnetothermal bioactive system that allows for regulation of MH temperature. The ionic and alkaline microenvironment from BSG degradation primarily impairs the malignant behavior of OS cells by activating the TNF signaling pathway. This sickening effect diminishes the hyperthermia tolerance of OS cells, thereby boosting apoptosis of OS cells, even in the presence of the limited anti-tumor effects of moderate MH. Furthermore, the combination of moderate MH and BSG also promotes optimal bone formation by stimulating human bone marrow mesenchymal stem cells (hBMSCs) via calcium and JAK-STAT3 signaling pathways. Collectively, this flourishes the therapeutic approaches and theories for the prevention and management of clinically refractory bone tumors.
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Scientific Reports
·
2025
·Vol. 15
·期 1
·1-14
·
IF 3.9
Zhou Lei,Zhang Mengting,Sun Huinan,Duan Liyuan,Meng Qingwei
This study establishes the first reversed-phase HPLC-UV method for simultaneous baseline separation of 12 structurally diverse water-soluble vitamins (WSVs) within 25 min. The eco-friendly approach utilizes a methanol–potassium dihydrogen phosphate (pH 4.85) gradient on a ChromCore C18 column (250 × 4.6 mm, 5 μm) with dual-wavelength detection (210/266 nm), eliminating environmentally detrimental ion-pairing reagents. Rigorous validation per ICH Q2(R1) guidelines confirmed excellent linearity (R² > 0.999), precision (RSD < 2.1%), accuracy (spike recoveries: 93.9–106.8%), and sensitivity (LODs: 0.01–0.78 µg/mL). The method resolved key analytical challenges including polarity disparities, matrix interference, and vitamin instability. Successful quantification of endogenous vitamins in DMEM medium showed ≤ 5.1% deviation from certified values for 11/12 analytes. Applied to five commercial MDCK cell culture media, the method revealed significant inter-product variability in vitamin composition – notably universal under-supplementation of riboflavin (0.576–0.741 µg/mL, 10× lower than other vitamins) and inconsistent biotin/adenine supplementation. This robust, cost-effective platform provides biomanufacturers with a powerful quality control tool for optimizing vitamin supplementation in vaccine production systems, addressing a critical gap in cell culture analytics.
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RARE METALS
·
2025
·
IF 11
He Shuai,Zhao Man,Zhao Peipei,Ma Jiamin,Liu Chunmei,Xiao He,Zhang Li,Zhang Junming,Hu Tianjun,Wang Shengxiang,Pang Huan,Jia Jianfeng
Nickel-based catalysts display promising potential in integrated hydrogen production through methanol electrooxidation (MOR). The unavoidable self-oxidation from Ni(OH) 2 to NiOOH severely restricts their MOR performance. To inspire the progress of MOR before self-oxidation of Ni species by altering reaction pathways, a heterostructured Ni–WO 2 catalyst is constructed to follow the direct electrooxidation pathway of methanol. In-situ/ex-situ characterization techniques combined with density functional theory calculations reveal the constructed Ni–WO 2 heterostructure alters the electronic structure of Ni site. It’s found Ni–Ni bond in Ni–WO 2 becomes longer and the electrons transfer from Ni sites to W sites. This results in upshifted d band center of Ni site and its closing to the Fermi energy level, which optimizes the CH 3 OH adsorption and the deprotonation of *CH 3 O into *CH 2 O in potential-determining step. Moreover, the formed asymmetric adsorption sites increase the polarity of the methanol and the intermediate. As expected, CH 3 OH molecule is highly converted into HCOOH via direct electrooxidation pathway. This obtained Ni–WO 2 exhibits superior MOR activity with high peak current density of 325.26 mA cm −2 and performs long term of 90 h at 10 mA cm −2 in hydrogen production. This work provides an important guidance for designing efficient Ni-based samples for direct electrooxidation of methanol. Graphical abstract
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CHEMICAL PAPERS
·
2025
·
IF 2.5
Kong Weizhen,Mao Jiaming,Peng Qianqian,Qin Shucan,Shi Longmei,Wu Anshuang,Xu Shengyun,Shi Jianming,Liu Yanrong,Ma Yunqian
High-value-added sulfur products as well as hydrogen (H 2 ) can be obtained by electrolytic oxidation of hydrogen sulfide (H 2 S), which is a promising energy conversion technology that contributes to the resource utilization of the pollutants. In conventional sulfide oxidation reaction (SOR), the recovery of the anodic product typically requires additional acidification treatment, resulting in the unsustainable use of electrolyte. Here, a novel H 2 S direct electrolysis system with ionic liquid (IL)-based electrolyte, consisting of acetate-based ILs and NaOH aqueous solution, was investigated. Compared to single NaOH aqueous solution, [Hmim]Ac-based electrolyte showed high H₂S absorption capacity and best electrochemical performance for SOR. Significantly, the anodic sulfur product was proved to be α-sulfur, which could be self-precipitated from the electrolyte without extra acid. The [Hmim]Ac-based electrolyte has the highest equilibrium solubility of sulfur (30.8 g L −1 ), which was 2–3 times that of the conventional electrolyte of NaOH aqueous solution. It is mainly attributed to the synergistic coupling of ILs and NaOH for H 2 S absorption and the modulating effect of ILs. Under constant potential electrolysis at 1.2 V vs RHE in [Hmim]Ac-based electrolyte, the maximum current density reached 194.4 mA cm −2 , the maximum hydrogen production rate reached 3945 μmol h −1 , the Faraday efficiency reached 97.9%, and the sulfur recovery of 82.6%. The IL-based electrolyte can be reused for at least three cycles of absorption-electrolysis, holding promise for efficient and continuous electrolysis of H 2 S. Graphical abstract
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CATALYSIS LETTERS
·
2025
·Vol. 155
·期 9
·1-12
·
IF 2.4
Zhong Yuhang,Xu Hui,Li Zhiguo,Zhang Yuqi,Hou Jianyuan,Yuan Yuan,Liu Xingang,Zhang Renxi
This study demonstrates an innovative approach for green and efficient hydrogen production from seawater, utilizing Cu–Fe/Al 2 O 3 catalysts coupled with a dielectric barrier discharge (DBD) system. The catalytic performance was systematically evaluated under varying voltages and Cu/Fe ratios in a DBD reactor to optimize hydrogen production efficiency. Subsequent investigations focused on humidity and gas flow rate effects using the optimal catalyst (Cu/Fe/Al 2 O 3 = 2:1:9). Multimodal characterization (XRD, XPS, FTIR, OES) combined with DFT calculations revealed the mechanistic role of Cu–Fe/Al 2 O 3 in plasma-driven hydrogen generation. The synergistic interaction between Fe and Cu enhanced hydroxyl/hydrogen radical generation through improved adsorption, thereby boosting hydrogen evolution efficiency and yield. The optimized system achieved a maximum hydrogen yield of 7.4 g/kWh at 3 kV operating voltage, 3 L/min argon flow, and 100% relative humidity, establishing an energy-efficient pathway for sustainable hydrogen production from seawater. Graphical
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CATALYSIS LETTERS
·
2025
·Vol. 155
·期 9
·1-12
·
IF 2.4
Peng Zhou-Xin,Wu Yu-chen,Xiao Shi-Yun,Zhou Hua-Lan,Wang Sheng-Kang,Wang Xue-Song
Low-cost nickel catalyst (Ni@C/C) derived from a metal organic framework (MOF) was synthetized for the hydrodeoxygenation (HDO) of biomass-derived vanillin. Unlike expensive noble-metal catalysts, Ni@C/C achieves full conversion of vanillin to 2-methoxy-4-methylphenol (MMP)—a key biofuel precursor—under mild conditions (180 °C, 2 MPa H₂). Ni@C/C exhibited excellent catalytic activity for the HDO of vanillin in isopropanol. Moreover, the main product of vanillyl alcohol (VA) under N 2 was 4-(isopropoxymethyl)-2-methoxyphenol (iPMP). The possible mechanism of vanillin by using Ni@C/C catalyst was that Vanillin was hydrogenated to generate VA, and VA was hydrogenated on Ni@C/C to generate MMP by two HDO paths: (1) VA was directly HDO to generate MMP; (2) VA was hydrogenated with isopropanol to generate iPMP by dehydration, then iPMP was hydrogenated to produce MMP. The Ni-based catalyst is relatively cheap and the preparation method is facile, green, and easy to scale up, thus achieving a low-cost transformation of biomass to bio-oils and chemicals. Graphical
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Nature Chemistry
·
2025
·
IF 20.2
Li Lei,Cui Chunhua
Electrocatalysis has long been viewed as an interfacial process, so the role of bulk water redox chemistry remains largely unexplored. Here we demonstrate that electrolyte-induced water redox radicals activate reactants in bulk solution for electrocatalysis at electrified interfaces. Using formate as a model electrolyte, we show that hydrogen-bond disruption in bulk water generates redox radicals, which oxidize formate to generate C 1 intermediates, as revealed by electron paramagnetic resonance, high-resolution mass spectrometry and Raman spectroscopy. Formate concentration-dependent hydrogen-bond restructuring drives the sequential generation of water-derived radicals and reactive intermediates, establishing bulk water as an active redox mediator rather than a passive solvent. In situ electrochemical studies demonstrate that these C 1 intermediates migrate to the Cu cathode surface, enabling C–C coupling via radical-mediated pathways. This work challenges the conventional view of electrocatalysis as solely an interfacial process and offers an alternative design principle for efficient electrochemical synthesis through tailored electrolyte engineering.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 6
·1-11
·
IF 5.3
Cheng Yuliang,Zhao Yajie,Li Peizhen,Yu Hang,Xie Yunfei,Guo Yahui,Yao Weirong,Qian He
As one of the most extensively used antibiotics in aquaculture in China, enrofloxacin (ENR) tends to accumulate in human body and endanger people’s health. Rapid, sensitive, and facile assays for enrofloxacin are urgently needed. In this study, based on the solid-phase substrate preparation strategy combined with microsphere etching and magnetron sputtering, Ag@Au nanoparticle (Ag@Au NP) solid array (Ag@Au NSA) with high surface-enhanced Raman spectroscopy (SERS) enhancement factor (EF≈8.3 × 10 7 ) was developed. Finite-difference time-domain (FDTD) simulations revealed that the Ag@Au NSA achieved maximum electromagnetic enhancement (EM) under the following optimized conditions: 633 nm excitation wavelength, 7.9 nm Au shell thickness, and 30.5 nm Ag core size. Additionally, SERS mapping results confirmed both the excellent enhancement performance and signal reproducibility of Ag@Au NSA, due to the expected micro-region enhancement with long-term effects accompanied by a larger range of high-density “hot spots.” The proposed SERS sensing for ENR based on Ag@Au NSA had a limit of detection (LOD) of 0.076 ng/mL ( R 2 ≈ 0. 9991) and was further applied to real-sample detection of ENR in crayfish tail meat with good recoveries ranging from 91.36 to 112.60%, indicating its great potential in practice. Graphical
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 9
·1-14
·
IF 5.3
Zhang Tingting,Tao Qin,Chen Rong,Xu Wen,Xu Jun,Wang Xiaoying
A portable electrochemical sensor for simultaneous voltammetric determination of acetylcholine (Ach), serotonin (5-HT) and dopamine (DA) using magnetic multi-walled carbon nanotubes-decorated ferroferric oxide-Pt@Au nanoparticles (FM-Pt@AuNPs) composite nanozyme was developed. The application of the nanozyme perfectly solved the problem of the weak electroactivity of Ach and the overlapping electrochemical signal of 5-HT and DA. Benefiting from superior horseradish peroxidase (HRP)-like activity and huge specific surface area of the FM-Pt@AuNPs, the proposed sensor enabled to quantify ACh, 5-HT, and DA at the potential of + 0.9, + 0.35, and + 0.14 V, with detection limits of 2 nM, 15 nM, and 10 nM, respectively. The assay provides good analytical performances and clinical practicability in human serums samples. This is the first detection of Ach, 5-HT, and DA using voltammetry, and it is also a new attempt of nanozyme in the field of portable electrochemical sensors. The strategy could be used for detecting other small biomolecules, and provide a simple and potential way for early-stage diagnosis and management of neurological diseases. Graphical abstract
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Journal of Ocean University of China
·
2025
·Vol. 24
·期 6
·1827-1833
·
IF 1.2
Xin Wenyuan,Zhou Yunbing,Liu Daixi,Wang Cong,Sherwin K. B. Sy
Astaxanthin (AX) and vitamin E (VE) are widely consumed nutritional supplements in China, with its beneficial effects predominantly attributed to all-trans AX and VE. The aim of this study is to develop and validate a rapid and accurate method for quantifying the content of AX and VE in nutritional supplement products using highly sensitive 1 H NMR method. Coumarin was chosen as the internal standard. Specific signals from AX was optimal at H-7,7′ in the chemical shift range of δ 6.17–6.24 ppm, whereas the signals of VE at δ 2.59 ppm. To demonstrate the reliability of this analytical approach the proposed method underwent rigorous validation, specificity, limit of detection (LOD), limit of quantitation (LOQ), linearity, accuracy, precision, and recovery. The accuracy of the validation method was 3.10% for AX and 1.99% for VE. The results indicated that the method was precise and reliable. The method has been successfully applied to simultaneous quantification of AX and VE in nutritional supplements products.
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