FOOD AND CHEMICAL TOXICOLOGY
·
2014
·
IF 2.61
Bingjun Yang,Fang Hao,Jiarong Li,Kai Wei,Wenyu Wang,Rutao Liu
Chrysoidine is an industrial azo dye and the presence of chrysoidine in water and food has become an environmental concern due to its negative effects on human beings. Binding of dyes to serum albumins significantly influence their absorption, distribution, metabolism, and excretion properties. In this work, the interactions of chrysoidine with bovine serum albumin (BSA) were explored. Isothermal titration calorimetry results reveal the binding stoichiometry of chrysoidine to BSA is 1:15.5, and van der Waals and hydrogen bonding interactions are the major driving force in the binding of chrysoidine to BSA. Molecular docking simulations show that chrysoidine binds to BSA at a cavity close to Sudlow site I in domain IIA. However, no detectable conformational change of BSA occurs in the presence of chrysoidine as revealed by UV–vis absorption, circular dichroism and fluorescence spectroscopy studies.
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高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2022
·Vol. 169
·期 5
·053512
·
IF 4.386
Yuan Yuan,Dan Zhang,Guoxu Zhang,Peng Zhang,Feihu Zhang,Chunhui Yang,Yang Gan
The crystallographic orientation dependence of nanopattern morphology and size of electropolished Al at a fixed voltage (40 V) has been revealed and established. However, systematic experimental studies, with samples' crystallographic orientation exactly determined, on the effects of voltage on nanopattern morphology and size has been largely lacking. Here, miscut monocrystalline Al samples are electropolished in a common electrolyte at voltages 20–60 V. Various nanopatterns (pits, pits plus stripes, stripes, dots) with distinct morphologies emerge with increasing voltage. The findings that morphologies transform gradually with misorientation angle were explained from the perspective of surface structure sensitivity. Nanopattern sizes remain largely constant with misorientation angles but increase with voltages till about 40 V, level off and decrease at higher voltage. A reported model was reexamined to explain the observed voltage dependence of nanopattern size by considering the overlooked effects of voltage on dissolution and adsorption. These findings reveal the voltage and crystallographic orientation dependence of nanopattern morphology and size, and provide critical data for theoretical investigation into the nanopattern formation mechanism of electropolished Al.
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ELECTROCHIMICA ACTA
·
2019
·
IF 5.383
Suqi Huang,Zili Cui,Lixin Qiao,Gaojie Xu,Jianjun Zhang,Kun Tang,Xiaochen Liu,Qinglei Wang,Xinhong Zhou,Botao Zhang,Guanglei Cui
Due to the ex-situ assembly technology of solid-state electrolyte, solid-state lithium batteries commonly show a poor electrolyte/electrode interfacial contact. Herein, we report an in-situ polymerized poly (tetrahydrofuran) (PTHF)-based solid polymer electrolyte (PTSPE) to resolve the poor interfacial contact problem in solid state lithium batteries . The in-situ formed PTSPE exhibits a high ionic conductivity (2.3 × 10 −4 S cm −1 ) and a wide electrochemical window (4.5 V) at 60 °C. More importantly, the in-situ formed PTSPE improves interfacial compatibility remarkably, suppressing the growth of lithium dendrites . It is revealed that boron trifluoride initiator works as functional additive to form LiF and B-O species at interface layer of lithium metal anode , alleviating lithium dendrites growth and undesired parasitic reactions. An as-assembled LiFePO 4 /Li cell employing this in-situ formed PTSPE delivers a high discharge capacity of 142.3 mA h g −1 even after 100 cycles. The aforementioned results suggest that the in-situ polymerization technology of solid-state electrolyte is very promising for high-performance solid-state lithium batteries.
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高影响因子
BIOMATERIALS
·
2024
·
IF 12.8
Xiuping Cao,Liyang Fang,Yifan Jiang,Tao Zeng,Shiyan Bai,Shiqing Li,Yana Liu,Wukun Zhong,Chunhua Lu,Huanghao Yang
Telomere length plays a crucial role in cellular aging and the risk of diseases. Unlike normal cells, cancer cells can extend their own survival by maintaining telomere stability through telomere maintenance mechanism. Therefore, regulating the lengths of telomeres have emerged as a promising approach for anti-cancer treatment. In this study, we introduce a nanoscale octopus-like structure designed to induce physical entangling of telomere, thereby efficiently triggering telomere dysfunction. The nanoscale octopus, composed of eight-armed PEG (8-arm-PEG), are functionalized with cell penetrating peptide (TAT) to facilitate nuclear entry and are covalently bound to N-Methyl Mesoporphyrin IX (NMM) to target G-quadruplexes (G4s) present in telomeres. The multi-armed configuration of the nanoscale octopus enables targeted binding to multiple G4s, physically disrupting and entangling numerous telomeres, thereby triggering telomere dysfunction. Both in vitro and in vivo experiments indicate that the nanoscale octopus significantly inhibits cancer cell proliferation, induces apoptosis through telomere entanglement, and ultimately suppresses tumor growth. This research offers a novel perspective for the development of innovative anti-cancer interventions and provides potential therapeutic options for targeting telomeres.
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PubMed
高影响因子
CATALYSIS TODAY
·
2015
·
IF 3.893
Faheem Nawaz,Yongbing Xie,Hongbin Cao,Jiadong Xiao,YueqiuWang,Xihua Zhang,Mingjie Li,Feng Duan
Two series of α-MnO 2 materials were prepared via a similar method with surfactant cetyltrimethylammonium bromide (CTAB) and sodium dodecyl benzene sulfate (SDBS). The surfactants work both as shape directing agent and reduction initiator. The α-MnO 2 synthesized with 0.2 M of CTAB showed a mesoporous structure with high surface area of 387.7 m 2 /g. It is very active in catalytic ozonation of 4-nitrophenol (4-NP) and total organic carbon removal, with higher catalytic stability than commercial MnO 2 . Using tert -butanol and p -benzoquinone as scavengers of different oxidative species, we found that superoxide radicals, rather than hydroxyl radicals, were mainly responsible for the degradation of 4-NP.
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高影响因子
APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Yichuan Li,Guofu Zhu,Yu Wang,Yongming Chai,Chenguang Liu,Shengbao He
Oriented molecular sieve membranes prepared on the surface of a specifically shaped substrate have been applied in the separation and catalysis process, but there is no report on the directional growth of molecular sieve membranes on the surface of spherical substrates. Here, a simple in situ crystallization method was employed to successfully prepare a single layer of b-oriented continuous titanium silicalite-1 (TS-1) molecular sieve membrane on the surface of 2-mm alumina beads. First, a titania intermediate layer was loaded on the surface of beads by the dipping method, and the surface was then modified with the TBOT modification solution. The ratio of the precursor solution was n(TEOS):n(TBOT):n(TPAOH):n(H 2 O) = 1:0.010:0.15:40 and was crystallized at 180 °C for 72 h to prepare the membrane. The content of the templating agent and water affected the size of TS-1 crystal grains and membrane crosslinking—both in turn influenced the continuity and orientation of the molecular sieve membrane. Spherical membrane catalyst was applied to catalyze the epoxidation of chloropropene in a fixed bed reactor, and the conversion of hydrogen peroxide and selectivity of epichlorohydrin attained 87.4% and 93.2%, respectively. This work provides a foundation for the design of novel TS-1 immobilized catalyst.
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高影响因子
RSC Advances
·
2016
·Vol. 6
·期 85
·81802-81808
·
IF 3.289
Hua Ge,Wei Wang,Ying Pan,Xiaojuan Yu,Weizhao Hu,Yuan Hu
Inherent flame retardation has the advantage that it will allow polymers to impart the flame retardancy permanently, and the introduction of even a few weight percent of the flame retardant unit can lead to remarkable improvements in the overall flame retardancy. In this paper, DDP was acyl-chlorinated as the monomer to synthesise the inherent flame-retardant polyamide by interfacial polymerization. Then, the chemical structures, crystalline structures, molecular weight, thermal properties, thermal stabilities and flame retardancy of the resultant polyamides were studied. The results show that the inherent flame-retardant polyamide has good thermal stability, Td of the samples were all above 310 °C. Furthermore, the incorporation of DDP, just 7.5 mol%, into the molecular chain can significantly improve the flame retardancy of polyamide, causing the pHRR value to be reduced by 37.8%.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2020
·
IF 4.65
Weide Wang,Dongxu Yao,Hanqin Liang,Yongfeng Xia,Kaihui Zuo,Jinwei Yin,Yu-Ping Zeng
This work reports the two-step sintering method and thermal conductivity of Si 3 N 4 doped with 1.5 wt% MgO and varied contents of ZrH 2 in the range of 0-5 wt%. The metal hydride reduction reaction in the first step sintering allows the in situ generations of ZrO 2 and the elimination of native SiO 2 . A smaller amount of liquid phase with reduced oxygen content was produced during the second step sintering as a result of the replacement of ZrO 2 by ZrH 2 . With the aid of ZrH 2 as an oxygen getter, the native oxygen in those ZrH 2 -doped samples was removed via a route of SiO 2 →ZrO 2 →SiO(g). Consequently, the densified Si 3 N 4 ceramics with larger volume percent of elongated purified β-Si 3 N 4 grains and less glassy phase were obtained. Ultimately, the optimal thermal conductivity of 116.4 W m −1 K −1 was achieved after sintered at 1900 °C for 12 h by using 3 wt% ZrH 2 and 1.5 wt% MgO as additives.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2020
·
IF 4.65
Yuzhe Wu,Qipeng Cai,Yuntong Li,Huixiang Liu,Jie Mao,Zhenwu Lu,Birong Zeng,Yiting Xu,Conghui Yuan,Lizong Dai
Incorporation of two or more types of metallic atoms into carbon matrix is of particular interest in the fabrication of high performance electrode materials. This normally requires complex synthetic routes or intricate post-processing process. Moreover, the composition and morphology of the resultant carbon materials are uncontrollable. Herein, we show the first time that a bimetal ions (Sn 4+ and Fe 3+ ) etching method based on Kirkendall effect can transform boronate polymer assemblies into metallosupramolecular polymer hollow spheres, which can be carbonized into carbon shells comprising FeSn 2 alloy. The carbon shells display evidently improved activity towards oxygen reduction reaction with onset potential 0.94 V and half-wave potential 0.84 V vs. RHE, which are comparable to that of Pt/C. The as formed FeSn 2 alloy in the carbon matrix possesses characteristics of rich in electrons, excellent conductivity and high chemical activity. Our supramolecular approach is simple, and able to control both the composition and morphology of the carbon materials, which may afford a new strategy for the design of higher performance electrochemical catalysts.
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Interdisciplinary Materials
·
2022
·Vol. 1
·期 4
·526-536
·
IF 0
Wanjia Tian,Peiquan Song,Yaping Zhao,Lina Shen,Kaikai Liu,Lingfang Zheng,Yujie Luo,Chengbo Tian,Liqiang Xie,Zhanhua Wei
Carrier recombination at the buried SnO 2 /perovskite interface limits the efficiency and stability of n-i-p-structured perovskite solar cells (PSCs). Herein, we report an In 2 O 3 interfacial layer with the distinctive structure of the monolithic compact/nanostructured bilayer. The partial hydrolysis nature of the In 3+ ion enables the formation of nanorods on top of the compact In 2 O 3 layer when spin-coating the In(NO 3 ) 3 aqueous solution. This novel interfacial layer reduces the pinholes of the SnO 2 film and increases the contact area between the perovskite and electron transport material. Therefore, PSCs with the incorporation of the interfacial layer demonstrate enhanced electron extraction and suppressed carrier recombination. Consequently, the champion device achieves a power conversion efficiency of 23.87% with a high fill factor of 82.14%. The optimized device also shows robust operational stability, retaining over 80% of the initial power conversion efficiency after working at the maximum power point for over 500 h under continuous one-sun illumination.
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JOURNAL OF MATERIALS SCIENCE
·
2021
·Vol. 56
·期 33
·18697-18709
·
IF 4.22
Zhang Li,He Miaomiao,Chen Lingdong,Xu Pinghua,Bao Jiaohui,Hu Xiuyuan
The excellent mechanical properties and high-water retention of hydrogels will expand the application in the field of biomedical materials. In this work, we prepared hydrogel based on methacryloyl gelatin (GelMA), sulfobetaine and quaternized chitosan (QCS) by “one-pot” method. GelMA acts as cross-linking agent to cross-link the PSBMA network. QCS chains are interspersed in the PSBMA network. The hydrogel obtained after the polymerization initiated by ultraviolet light is further immersed in glycerin for solvent replacement. The hydrogel exhibits excellent mechanical properties with a breaking stress of 4.73 MPa and a breaking strain of 160%. After 100 successive loading–unloading cycles, the hydrogel remains intact and the maximum load decreases slightly. In addition, the hydrogel has excellent antifreeze properties and remains flexible and transparent after being placed at − 20 °C for three days. Antibacterial experiments proved that hydrogel could effectively resist the adhesion of E. coli . In the trypsin solution, the hydrogel will be degraded, and the degradation rate can be regulated by trypsin concentration. The hydrogel also has good water retention and biocompatibility and is expected to be used in biological tissue replacement and medical devices.
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高影响因子
Materials
·
2024
·Vol. 17
·期 11
·2570
·
IF 3.1
Yu Kong,Rong Zhang,Boyang Li,Wei Zhao,Ji Wang,Xiao-Wen Sun,Huihui Lv,Rui Liu,Juan Tang,Biao Wu
Phosphates play a crucial role in drug design, but their negative charge and high polarity make the transmembrane transport of phosphate species challenging. This leads to poor bioavailability of phosphate drugs. Combretastatin-A4 phosphate (CA4P) is such an anticancer monoester phosphate compound, but its absorption and clinical applicability are greatly limited. Therefore, developing carrier systems to effectively deliver phosphate drugs like CA4P is essential. Anion receptors have been found to facilitate the transmembrane transport of anions through hydrogen bonding. In this study, we developed a tripodal hexaurea anion receptor (L1) capable of binding anionic CA4P through hydrogen bonding, with a binding constant larger than 104M−1in a DMSO/water mixed solvent.L1demonstrated superior binding ability compared to other common anions, and exhibited negligible cell cytotoxicity, making it a promising candidate for future use as a carrier for drug delivery.
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PubMed
高影响因子
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