EUROPEAN FOOD RESEARCH AND TECHNOLOGY
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2026
·Vol. 252
·期 7
·280
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IF 4.2
Pan Shenrui,Wu Jiali,Liu Dan,Sun Jianxia,Bai Weibin
Aloe-emodin (AE), a natural photosensitizer, suffers from poor aqueous solubility that limits its photodynamic efficacy. This study developed a novel food-friendly co-amorphous system using ferulic acid (FA) as a co-former to enhance AE’s solubility and photodynamic performance. The AE-FA co-amorphous mixture was characterized by powder X-ray diffraction (PXRD), differential scanning calorimetry (DSC), and Fourier-transform infrared spectroscopy (FTIR) with molecular dynamics simulations confirming hydrogen bond formation. Results demonstrated that this complexation effectively reduced the lattice energy of AE, leading to significantly improved solubility and physical stability of the CAM system. Furthermore, AE-FA CAM exhibited enhanced antimicrobial photodynamic activity against Staphylococcus aureus compared to pure AE, which was attributed to reduced molecular agglomeration and alleviated fluorescence quenching. This study aims to develop a novel, food-friendly co-amorphous system to simultaneously enhance the solubility and photodynamic efficacy of AE. This work presents the first report of a co-amorphous system between AE and FA specifically designed for photodynamic applications, providing an effective strategy to overcome solubility limitations of natural photosensitizers in food safety applications.
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JOURNAL OF CHEMICAL ECOLOGY
·
2026
·Vol. 52
·期 4
·58
·
IF 2.1
Ma Qianwen,Li Qin,Tan Tingting,Meng Yifei,Wang Hongquan,Chen Yiqu,Tang Xiaoqin
Quercus aquifolioides is an ecologically important oak species on the Qinghai–Tibet Plateau that experiences significant damage from Soritia leptatina . To clarify the behavioral response of S. leptatina to leaf volatiles of Q. aquifolioides , we analyzed leaf-associated volatile organic compounds using solid-phase microextraction coupled with gas chromatography–mass spectrometry (SPME–GC–MS), measured electrophysiological and behavioral responses of adult S. leptatina to selected leaf volatiles using electroantennography (EAG) and Y-tube olfactometer assays, and evaluated the field-trapping potential of bioactive volatiles. The detected leaf-associated profile included C6 green-leaf-volatile derivatives, long-chain fatty acids and fatty-acid esters, terpenes, and aromatic compounds. Unmated male and female adults showed strong EAG responses to leaf acetate, palmitic acid, and myristic acid, with the highest response recorded for 10 µg/µL leaf acetate (0.97 mV). Y-tube assays indicated that leaf acetate, myristic acid, and naphthalene elicited significant behavioral attraction at specific concentrations ( P < 0.05), whereas palmitic acid did not show significant attraction in this assay. Field trapping experiments further showed that palmitic acid and myristic acid increased adult captures, with 100 µg/µL myristic acid producing the highest catch (137 individuals). These results suggest that myristic acid and palmitic acid may be useful for monitoring, early warning, and environmentally friendly management of S. leptatina , although their behavioral roles should be interpreted according to assay type and concentration.
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PubMed
高影响因子
Journal of Central South University
·
2026
·
IF 4.7
Guo Meng-wei,Chai Zheng,Shao Wei-chun,Gao Ming-yuan,Deng Rong-rong,Ru Juan-jian,Xu Cun-ying,Li Yan,Hua Yi-xin,Zhang Qi-bo
Zinc anode slime (ZAS), a metallurgical byproduct generated during zinc electrowinning, contains Mn, Pb, Fe, and trace amounts of Ag. Hydrodynamic instabilities in the electrolyte circulation system cause ZAS particles to remain suspended, thereby compromising electrodeposition kinetics and the purity of cathodic zinc. Consequently, periodic removal and valorization of ZAS are necessary. This study proposes a novel hydrometallurgical route for recovering high-purity Mn 2 O 3 from ZAS. The process integrates sulfuric acid leaching with thiourea (TU) reduction, followed by sequential purification, precipitation, and calcination. Under optimized conditions (ZAS:TU mass ratio of 10:3, 200 g/L H 2 SO 4 , solid-to-liquid ratio of 1:5, temperature of 60°C, duration of 2 hours, and 100-mesh ZAS particle size), a leaching efficiency of 91.39% for Mn is achieved. Subsequent precipitation recovers 96.21% of Mn as Mn(OH) 2 , resulting in Mn 2 O 3 after calcination. Kinetic analysis indicates that the reaction follows the unreacted shrinking core model, with mixed control by interfacial reactions and ion diffusion ( E a =35.87 kJ/mol). This work elucidates the reaction mechanisms and establishes a viable route for the valorization of industrial metallurgical residues.
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Nature Communications
·
2026
·
IF 18.1
Xu Wenyu,Chang Zelin,Wang Hongwei,Ding Hongbo,Zhi Chunyi,Li Xinliang
The chlorine-based batteries exhibit persistent issues with the evolution of toxic gaseous chlorine at ambient temperatures, which severely compromise conversion reversibility, cycling stability, and corrode vital battery components, despite their promising capacity and voltage. Here, we propose the coordination-locked liquefaction electrochemistry mediated by ionic liquid for constructing energetic aqueous zinc||chlorine batteries based on liquid-liquid modes. The amphiphilic ionic liquid nanoclusters optimize the halogen conversion mechanism, Zn redox, and electrolyte stability. Consequently, the zinc||chlorine battery shows long-term durability with 0.0017% capacity fade per cycle over 10000 cycles at 10.0 A g –1 , a large capacity of 541.9 mAh g –1 Cl at 1.0 A g –1 , and a high discharge voltage plateau of 1.78 V at 1.0 A g –1 . The activated one-step liquid-liquid conversion modes eliminate gas formation, corrosion, and the need for non-standard components. The synergistic interplay of multifaceted spectroscopy and computational modeling uncovers the halogen redox mechanism and the mass-charge transfer process. Furthermore, the universality and efficiency of the emergent redox electrochemistry are verified across zinc||iodine and zinc||bromine batteries, spanning conventional two-electron and frontier four-electron transfer mechanisms. This work unlocks halogen electrochemistry and establishes a transformative blueprint for designing high-performance halogen batteries.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2026
·
IF 4.1
Wei Ming,Qin Yanxin,Ma Zhichao,Zhu Yunwei,Wang Yiran,Tong Wenting,Ma Lijuan,Lu Wenbo
The recycling of agricultural and electronic waste is pivotal to realizing the circular economy and green chemistry principles. This work successfully fabricated an electrochemical sensor using cattle manure and graphite rods from spent batteries, achieving quantitative determination of capsaicin (CAP) in pickled vegetables. Distinct from previous biochar-based sensors that focus on single waste streams or multi-step modifications, this work introduces a dual-waste synergistic upcycling strategy. The CoPc@SiO 2 @BC was prepared via a straightforward one-step pyrolysis process, which involved using cattle manure as the carbon source, and characterized by a suite of techniques. The CoPc@SiO 2 @BC was loaded onto a graphite rod recovered from spent batteries after simple surface treatment, forming a sensor that exhibited remarkable detection performance for CAP. It demonstrated a wide linear range from 0.5 to 1500 μM, a low detection limit of 0.26 μM, along with good selectivity, repeatability, and stability, confirming its capability for real-sample analysis. This synergistic utilization of dual waste resources not only reduces electrode fabrication costs but also enhances analytical sensing performance, thereby providing a novel pathway for developing green electrochemical sensing technologies.
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ACTA PHARMACOLOGICA SINICA
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2026
·
IF 10.4
Jiang Feng,Fu Huang-xi,Wang Lan,Pan Ze-zheng,Jiang Yan-qi,Liu Ning,Chen Xue-qin,Gao Zi-zheng,Wu Wen-tong,Yan Hao,Yang Xiao-chun,Yang Bo,He Qiao-jun,Luo Pei-hua,Xu Zhi-fei
Ceritinib, an anaplastic lymphoma kinase (ALK) inhibitor, is associated with cardiovascular adverse events, yet the mechanisms remain incompletely understood. Here, we show that ceritinib impairs left ventricular systolic function in mice and induces cardiomyocyte apoptosis, and identify AKT (Ser473) suppression as a key initiating event. Loss of AKT activity is paralleled by reduced phosphorylation of mTOR (Ser2448) and ULK1 (Ser757), consistent with enhanced autophagy initiation. Concurrently, loss of inhibitory GSK3β (Ser9) phosphorylation correlates with impaired lysosomal function, reflected by disrupted cathepsin D maturation and reduced lysosomal acidification. This mismatch between enhanced autophagy initiation and impaired lysosomal clearance impairs autophagic flux despite preserved autophagosome-lysosome fusion, and causes mitochondrial damage, evidenced by reduced TOMM20 and HSP60 expression and membrane potential loss. Transcriptomic and functional analyses identify AKT2 as a particularly vulnerable isoform in this network. Metformin co-treatment preserves cardiac function and attenuates apoptosis. Mechanistically, metformin increases AMPK (Thr172) phosphorylation and reduces TFEB (Ser122) phosphorylation, restores CTSD maturation, and decreases LC3-II accumulation. These protective effects occur without reversing the suppressed AKT (Ser473) or GSK3β (Ser9) phosphorylation. Together, these findings establish that AKT suppression drives ceritinib cardiotoxicity through autophagic flux impairment and mitochondrial injury, and position AMPK-driven, TFEB-associated lysosomal restoration as a mechanism-based cardioprotective strategy independent of AKT recovery.
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JOURNAL OF POLYMER RESEARCH
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2026
·Vol. 33
·期 8
·354
·
IF 3.5
Zhang Feng,Yao Ying,Zhao Keli,Guo Ming
The synergistic removal of wastewater containing heavy metals and organic pollutants remains a major challenge. Although multifunctional materials can enable one-step treatment, their high cost limits practical application, making sequential treatment with single-functional materials a feasible strategy. In this study, two lignin-based hydrogels were developed for stepwise removal of heavy metals and tetracycline (TC). Iron-manganese-modified lignin hydrogel (IM-LH) was prepared by copolymerizing acrylamide with lignin, in situ loading iron and manganese ions, and subsequent sulfuration, enabling efficient adsorption of Cd(II) and As(III). The immobilized enzyme composite hydrogel (HRP@HPAAM-LA) is made by chemically attaching horseradish peroxidase (HRP) to the pores and surfaces of a lignin-based semi-interpenetrating network carrier (HPAAM-LA), which is built through free radical copolymerization, using an EDC/NHS-mediated amidation reaction. This material can both adsorb and concentrate TC while letting HRP carry out oxidative degradation. The hydrogels were characterized by SEM, FTIR, XRD, XPS, and TGA, and their continuous removal performance and mechanisms were investigated. Both hydrogels exhibited uniform porous networks and abundant active sites. IM-LH showed maximum adsorption capacities of 86.20 mg·g − 1 for Cd(II) and 60.01 mg·g − 1 for As(III), retaining removal rates of 65.46% and 51.44% after 15 cycles. HRP@HPAAM-LA achieved an HRP immobilization rate of 78.13% and a TC removal rate of 92.22%, retaining 61.82% after 13 cycles. This study successfully prepared two lignin-based hydrogels, achieving the synergistic removal of heavy metals and organic pollutants. It provides a new method for the hierarchical and synergistic treatment of complex environmental wastewater, while also promoting the high-value utilization of biomass resources in environmental remediation.
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CHINESE JOURNAL OF POLYMER SCIENCE
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2026
·
IF 4.6
Qian Yue-Yuan,Sun Xiang-Bin,Liu Ya-Lei,Li Zhi-Bo
As plastic pollution has become increasingly severe, the development of recyclable and rapidly degradable polyesters has significant practical value and significance. In this study, seven-membered cyclic 1,3-propylene glycol oxalate (POx) was successfully synthesized through a two-step polycondensation-depolymerization method using dimethyl oxalate (a low-cost and readily accessible bulk chemical) and bio-based 1,3-propylene glycol as the starting materials. Using Sn(Oct) 2 as the catalyst, high-molecular-weight poly(1,3-propylene oxalate) (PPOx) was efficiently prepared via ring-opening polymerization (ROP) of POx. This ROP demonstrated excellent reactivity, attaining a monomer conversion up to 95% within 10 min, and PPOx had a maximum intrinsic viscosity ( η ) of 1.06 dL/g. Furthermore, the prepared PPOx could be catalytically depolymerized to enable efficient recovery of the POx monomer, with a yield of 60% and a purity of 98%. The degradation performance tests indicated that PPOx exhibited rapid degradation, reaching a degradation rate of up to 99% within 50 days. Owing to the innovative selection of raw materials and the design of a closed-loop process, this study provides a new economical and sustainable strategy for reducing dependence on petroleum resources, offering valuable insights into the development of recyclable and rapidly degradable polyesters.
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Nature Nanotechnology
·
2026
·
IF 37.5
Jin Ruo-Xi,Lei Xincheng,Su Xiao-Chuan,Zhang Xing,Zhao Yao,Qi Xiaodong,Lu Zhuo-Ya,Zhang Xu-Sheng,Zhang Yu-Ying,Zhang Jin,Yuan Qingxi,Zhang Jing,Zheng Lirong,Guo Yu-Jie,Xin Sen,Su Dong,Wen Rui,Wan Li-Jun,Guo Yu-Guo
The Fe( III )|Fe( IV ) redox couple in iron-containing Na layered oxides enables high-capacity, cost-effective positive electrodes. However, although a high iron content (when the Fe concentration exceeds 33 at.% on transition metal layers) leads to rapid capacity decay during battery cycling, the underlying mechanism of this detrimental behaviour remains unclear. Here we report that the electrochemomechanical failure mechanism in Fe-rich Na layered oxides is related to the stability of the Fe octahedral coordination environment at the nanoscale. Fe-ion migration and dissolution govern the formation of intragranular microcracking in the positive electrode active material particles, accompanied by dislocations and an uneven distribution of mechanical stress. Driven by the non-uniform strain field, microcracks proliferate and planar gliding occurs, resulting in a stepped surface. By nanoscale doping with Al( III ) (1 at.%), Y( III ) (1 at.%) and Co( III ) (3 at.%), we inhibit the Fe-ion migration and dissolution, thereby reducing cracks and planar gliding. Using the multi-element nanoscale-doped iron-rich sodium layered oxide at the positive electrode and a hard-carbon-based negative electrode, we assembled and tested 2.7-Ah Na-ion pouch cells showing an initial specific energy of 121 Wh kg −1 (based on the total mass of the cell) at 26 mA g −1 , and a discharge capacity retention of 83.4% after 2,000 cycles at 130 mA g −1 at 25 °C.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2026
·
IF 4.1
Hu Zhi,Xiao Jinna,Hu Lianqi,Xie Haijiao,Liao Zhengzheng,Li Zhentao
The increasing misuse of psychiatric drugs has led to their emergence as environmental contaminants in water and food matrices, raising public health concerns. In this study, a hydroxyl-rich covalent organic framework (Py-DHBD-COF) was solvothermally synthesized and coated onto a stainless steel fiber for use in direct-immersion solid-phase microextraction (DI-SPME). The fabricated fiber was employed to extract psychiatric drugs from environmental water and pretreated milk extracts, followed by analysis using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The hydroxyl-rich structure of the Py-DHBD-COF coating can provide hydrogen-bonding, hydrophobic interactions, and π-π interactions with the target analytes, resulting in high extraction efficiency. Key parameters affecting extraction performance, including extraction time, volume, pH, and desorption conditions, were systematically optimized. Under optimal conditions, the method exhibited good linearity ( R 2 = 0.9992–0.9996) for quetiapine, olanzapine, and clozapine over a concentration range of 1–500 ng/mL, with low limits of detection (0.010–0.024 ng/mL). The reproducibility was satisfactory, showing relative standard deviations below 5.38%, and recoveries ranged from 85.1 to 114.6% in both sample matrices. These results demonstrate that the proposed SPME-HPLC-MS/MS method is a sensitive, reliable, and environmentally friendly approach for monitoring trace levels of psychiatric drugs in complex water and milk samples. Graphical abstract
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Nano-Micro Letters
·
2026
·Vol. 18
·期 1
·439
·
IF 38.5
Li Kaiyuan,Li Linhong,Song Guichen,Qin Yue,Chen Hanxi,Zhao Zujian,Yang Boren,Zhou Yiwei,Wang Yandong,Yang Rongjie,Li Maohua,Chen Fei,Cai Tao,Lin Cheng-Te,Nishimura Kazuhito,Jiang Nan,Yu Jinhong
With the trend toward high-power radio-frequency (RF) electronic devices, flexible thermally conductive composite films are regarded as a key engineering interfacial material to address the critical problem of signal transmission and heat dissipation. However, achieving simultaneous optimization of high thermal conductivity and low loss in the same material remains a significant challenge, particularly in films with high filler loading. Here, a bottom-up regulatory strategy is proposed to address this challenge. Through the synergistic optimization of interface modification design and spatial orientation arrangement of hexagonal boron nitride (BN), the fabricated composite film achieves an exceptional in-plane thermal conductivity of 78.50 W m⁻ 1 K⁻ 1 , significantly surpassing that of the film with BN. This remarkable enhancement is primarily attributed to the altered surface properties of the aminated BN (BN-NH 2 ). The introduction of amine groups enhances the compatibility with the polymer matrix through electrostatic interactions to facilitate more efficient interfacial thermal transport. Furthermore, the highly oriented spatial arrangement of BN in the film not only preserves the electromagnetic wave transparency (99.94%), but also enhances its breakdown strength. This study underscores the critical role of molecular-level filler modification combined with micro-nanostructural engineering in synergistically strengthening the filler-matrix interface and boosting film thermal transport.
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JOURNAL OF NANOPARTICLE RESEARCH
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2026
·Vol. 28
·期 8
·219
·
IF 3.5
Hu Xingao,Wang Yuxiang,Wang Song,Tan Liqiang
The growing application of engineered nanoparticles has heightened concerns regarding their environmental release; gaining a robust understanding of their transport mechanisms, environmental fate, and behavioral dynamics in natural aquatic systems is therefore of particular importance. This study systematically investigated the aggregation and disaggregation behavior of ZnO nanoparticles in the presence of humic acid (HA) and/or Ca 2+ ions across a range of pH values. Additionally, controlled shear conditions were applied to assess the influence of hydrodynamic shear forces on ZnO nanoparticle stability. The addition of HA to the suspensions resulted in a significant decrease in zeta potential and an increase in the hydrodynamic diameter of ZnO nanoparticles, implying the occurrence of charge neutralization between nanoparticles. High shear forces were sufficient to overcome interparticle attractive forces, thereby disaggregating large particle clusters into smaller entities; in contrast, low shear forces promoted nanoparticle aggregation by enhancing collision frequency and efficiency. Higher strength factors (SF) values observed in reaction systems with elevated Ca 2+ ion concentrations indicated that aggregates formed under such conditions exhibited more compact structures and greater resistance to shear-induced fragmentation. Fluorescence spectra analysis indicated that the compact structure of ZnO nanoparticles formed under high Ca 2+ ion concentrations was most likely due to the strong chemical binding with HA and bridging mechanisms involving divalent cations formed during the aggregation process. The findings of this study provide a mechanistic basis for predicting the environmental fate and transport behavior of ZnO nanoparticles in natural aquatic environments.
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