Biomass Conversion and Biorefinery
·
2024
·
IF 3.5
He Taotao,Wang Fei,Feng Junfeng,Liu Yancong,Chen Yuwei,Guo Feihong,Liu Peng,Jiang Xiaoxiang,Jiang Jianchun
To efficiently convert the microalgae to valuable and renewable fuels, the microalgae oil was first extracted and then transformed into the second-generation biodiesel. Among all solvents that were used for the microalgae oil extraction, the polar single solvent system methanol achieved the optimal value (47.8% extraction yield) because the polar cell membrane was easily dissolved by the polar solvent. Hexadecanoic acid (38.54%) and docosanoic acid (54.39%) dominated in fatty acid of microalgae oil. In the catalytic deoxygenation of microalgae oil, the Co-Al nanosheet displayed a higher performance than Co/Al 2 O 3 because of its high Co content and lamellar structure, exposing massive Co sites with high dispersion and small particle size. Moreover, when the reaction temperature was raised to 240 °C, the 100% conversion and 100% alkane yield were obtained, and the further temperature rise in temperature led to the cracking reaction. Graphical Abstract
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2023
·Vol. 30
·期 8
·1-7
·
IF 2.8
Wu Fang,Pu Zejun,Hou Hongbo,Li Xianyong,Zhu Rongli,Wang Xu,Yu DaYang,Zhong Jiachun
Bioderived polycarbonate (ISB-PC) was synthesized via transesterification and polycondensation of isosorbide (ISB) and diphenyl carbonate (DPC) using lithium acetoacetone as a catalyst. The resulting ISB-PC exhibited high glass transition temperatures similar to bisphenol A polycarbonate (BPA-PC) and was thermally stable up to 350 ℃. The incorporation of isosorbitol into the polymer chain imparted an improved mechanical property of ISB-PC, such as a higher bending and tensile modulus and higher elongation at break. ISB-PC can be readily cast into transparent films with a tensile strength of 73.3 MPa and a tensile modulus of 534 MPa. ISB-PC displayed high UV transmittance and possessed blue fluorescence under UV irradiation. At the same time, ISB-PC also has strong anti-yellowing ability.
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高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2019
·Vol. 37
·期 5
·451-461
·
IF 2.804
Niu Jun-Long,Chai Ke-Ke,Zeng Mei-Xing,Wang Tian-Tian,Zhang Chun-Yan,Chen Shuai,Xu Jing-Kun,Duan Xue-Min
To prepare chiral monomer with single chiral center and higher stereospecificity, a pair of amino-functionalized chiral 3,4-propylenedioxythiophene (ProDOT) derivatives, chiral (3,4-dihydro-2 H -thieno[3,4- b ][1,4]dioxepin-3-yl)methyl 2-[( tert -butoxycarbonyl) amino]-3-phenylpropanoate (ProDOT-Boc-Phe), were synthesized. Chiral poly[(3,4-dihydro-2 H -thieno[3,4- b ][1,4]dioxepin-3-yl)methyl 2-[( tert -butoxycarbonyl)amino]-3-phenylpropanoate] (PProDOT-Boc-Phe) modified electrodes were synthesized via potentiostatic polymerization of chiral ProDOT-Boc-Phe. Chiral PProDOT-Boc-Phe films displayed good reversible redox activities. The enantioselective recognition between chiral PProDOT-Boc-Phe modified glassy carbon electrodes and DOPA enantiomers was achieved by different electrochemical technologies, including cyclic voltammetry (CV), square wave voltammetry (SWV), and differential pulse voltammetry (DPV). (D)-PProDOT-Boc-Phe and (L)-PProDOT-Boc-Phe showed higher peak current responses toward L-DOPA and D-DOPA, respectively.
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高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-11
·
IF 14.7
Zhou Xuefan,Zhang Jun,Luo Hang,Zhang Yan,Tang Shiyu,Huang Houbing,Yuan Xi,Song Miao,Qi He,Zhang Dou
The trade-off between electrostrain and strain hysteresis for piezo/ferroelectric materials largely restrains the development of high precision actuators and remains unresolved over the past few decades. Here, a simple composition of (Bi 0.5 Na 0.5 ) 1- x /100 Sr x /100 TiO 3 in the ergodic relaxor state is collaboratively designed through the segregated domain structure with the ferroelectric core, local polarization heterogeneity, and defect engineering. The ferroelectric core can act as a seed to facilitate the field-induced nonpolar-to-polar transition. Together with the internal bias field caused by defect dipoles and adjusted through electric field cycling and heat treatment technology, a giant unipolar strain of 1.03% is achieved in the x = 30 ceramic with a low hysteresis of 27%, while the electric-field-independent large-signal piezoelectric strain coefficient of ~1000 pm/V and ultralow hysteresis of <10% can be obtained in the x = 35 ceramic. Intriguingly, the low-hysteresis high strain also exhibits near-zero remnant strain, excellent temperature and cycling stability.
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高影响因子
Scientific Reports
·
2022
·Vol. 12
·期 1
·1-8
·
IF 4.996
Weng Yue,Su Chun-Jen,Jiang Haoyang,Chiang Chien-Wei
Site-selectively chemical bioconjugation of peptides and proteins can improve the therapeutic exploration of modified protein drugs. Only 3.8% natural abundance of phenylalanine in protein and nearly 90% of proteins contain at least one phenylalanine residue in their sequenced, showing the potential in biopharmaceutical utility of the phenylalanine bioconjugation. However, the covalent bioconjugation of native phenylalanine is one of the most challenging problems in protein modification. Herein, an approach to protein modification is described that relies on a photoredox method for the site-selective bioconjugation of phenylalanine. This methodology has been validated on peptides as well as protein insulin using a straightforward and mild condition. In addition, based on characterization by near-UV CD spectroscopy and small angle X-ray scattering (SAXS), this pyrazole labeling approach permitted the insulin hexamer to completely dissociate into the monomeric form, thus making it a potential candidate for use as rapid-acting insulin for the treatment of diabetes.
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高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-17
·
IF 14.7
Wang Huirui,You Xiaona,Wang Jingcheng,Chen Xinyi,Gao Yinghui,Wang Mengmeng,Zhang Wenru,Zhang Jiaozhen,Yu Yang,Han Bo,Qi Mei,Liu Xiaohui,Lou Hongxiang,Dong Ting
Hemolysis drives susceptibility to lung injury and predicts poor outcomes in diseases, such as malaria and sickle cell disease (SCD). However, the underlying pathological mechanism remains elusive. Here, we report that major facilitator superfamily domain containing 7 C (MFSD7C) protects the lung from hemolytic-induced damage by preventing ferroptosis. Mechanistically, MFSD7C deficiency in HuLEC-5A cells leads to mitochondrial dysfunction, lipid remodeling and dysregulation of ACSL4 and GPX4, thereby enhancing lipid peroxidation and promoting ferroptosis. Furthermore, systemic administration of MFSD7C mRNA-loaded nanoparticles effectively prevents lung injury in hemolytic mice, such as HbSS-Townes mice and PHZ-challenged 7 C −/− mice. These findings present the detailed link between hemolytic complications and ferroptosis, providing potential therapeutic targets for patients with hemolytic disorders.
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PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2024
·Vol. 59
·期 25
·11454-11467
·
IF 3.5
Yuan Yiheng,Yang Li,Peng Xishun,Chen Qixin,Li Xinghua,Zuo Cheng,Zhou Zhangyu,Bai Zhongchen
Here, we passivated the interfacial defects of ZnO/CsPbBr 3 by inserting a NaSCN layer between the ZnO electron transport layer and the CsPbBr 3 layer to improve the photoelectric conversion efficiency of ZnO/CsPbBr 3 /Carbon structure solar cell. The addition of the NaSCN optimized the morphology of the ZnO surfaces to decrease effectively the roughness. Furthermore, The passivated ZnO electron transport layer improved the deposition quality of CsPbBr 3 films, which reduced the defects at the interface between the ZnO electron transport layer and CsPbBr 3 layer, suppressing non-radiative recombination to enhance device photovoltaic performance. Synergistic passivation of SCN − and Na + ions plays an important role in obtaining high-quality CsPbBr 3 films for boosting the power conversion efficiency (PCE) of the device. Moreover, the passivated solar cells had longer stability than the pristine ones after being placed for 1000 h in the air and at room temperature.
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高影响因子
Animal Diseases
·
2024
·Vol. 4
·期 1
·1-16
·
IF 0
Liu Jinglei,Zhang Yuhan,Song Mengzhen,Guo Xuming,Fan Jinping,Tao Shiyu
Oxidative stress is an important contributor to gastrointestinal diseases in multiple ways. Taurodeoxycholic acid (TDCA) is a metabolite of bile acids and has anti-inflammatory and protective effects on the intestinal tract. However, whether TDCA can alleviate oxidative stress in the intestine is still unclear. Here, we investigated the effects of TDCA on diquat-induced oxidative stress in the jejunum and its mechanism. The results revealed that TDCA increased the concentrations of antioxidant enzymes in the serum, jejunal tissue and intestinal epithelial cells of the mice, as did the expression of tight junction-associated proteins and the Nrf2 protein in the jejunal epithelial tissue and intestinal epithelial cells. We then explored the mechanism of Nrf2 with ML385 (a specific Nrf2 inhibitor). The results showed that after ML385 treatment, the levels of antioxidant enzymes were significantly decreased in the serum, jejunum, and intestinal epithelial tissues of the mice. The expression of tight junction proteins in jejunum epithelial tissues and intestinal epithelial cells was also decreased. In conclusion, our study suggests that TDCA alleviates oxidative stress to improve intestinal barrier function through the Nrf2-mediated signaling pathway. These findings help elucidate the role of TDCA in protecting the intestinal barrier and its mechanism of action, providing insights for the prevention and treatment of intestinal diseases caused by oxidative stress.
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Journal of Animal Science and Biotechnology
·
2024
·Vol. 15
·期 1
·1-20
·
IF 6.3
Li Daojie,Cai Hongying,Liu Guohua,Han Yunsheng,Qiu Kai,Liu Weiwei,Meng Kun,Yang Peilong
Background Fatty liver hemorrhage syndrome (FLHS) becomes one of the most major factors resulting in the laying hen death for caged egg production. This study aimed to investigate the therapeutic effects of Lactiplantibacillus plantarum ( Lp. plantarum ) FRT4 on FLHS model in laying hen with a focus on liver lipid metabolism, and gut microbiota.
Results The FLHS model of laying hens was established by feeding a high-energy low-protein (HELP) diet, and the treatment groups were fed a HELP diet supplemented with differential proportions of Lp. plantarum FRT4. The results indicated that Lp. plantarum FRT4 increased laying rate, and reduced the liver lipid accumulation by regulating lipid metabolism (lipid synthesis and transport) and improving the gut microbiota composition. Moreover, Lp. plantarum FRT4 regulated the liver glycerophospholipid metabolism. Meanwhile, “gut-liver” axis analysis showed that there was a correlation between gut microbiota and lipid metabolites.
Conclusions The results indicated that Lp. plantarum FRT4 improved the laying performance and alleviated FLHS in HELP diet-induced laying hens through regulating “gut-liver” axis. Our findings reveal that glycerophospholipid metabolism could be the underlying mechanism for the anti-FLHS effect of Lp. plantarum FRT4 and for future use of Lp. plantarum FRT4 as an excellent additive for the prevention and mitigation of FLHS in laying hens.
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PubMed
高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2018
·Vol. 37
·期 9
·841-850
·
IF 2.016
Yang Lin-Can,Han Li,Ma Hong-Wei,Liu Pi-Bo,Shen He-Yu,Li Chao,Zhang Song-Bo,Li Yang
“Thiol-yne” click reaction has already been widely applied in synthesis and modification of new polymer structures or novel materials due to its specific features. However, in most studies, only chain-end strategy was employed when using the di-addition feature of thiol-yne reaction, thus the in-chain di-addition strategy could endow us with a broader space to develop the synthesis of advanced polymers. Therefore, in this paper, the features of in-chain mono- and di-addition were investigated when modifying the alkyne-functionalized polymers to prepare grafted polymers via thiol-yne click reaction. The results showed that it is almost impossible to obtain the in-chain di-adducts even under excess feeding of chain-end thiol-functionalized grafts, while only the in-chain mono-adducts could be obtained efficiently. Further researches investigated that the controlled grafting could be encountered when carrying out the thiol-yne click reaction between chain-end alkyne-functionalized polystyrenes and chain-end thiol-functionalized polystyrenes under proper feedings. Therefore, the effect of steric-hindrance might be the primary reason for the alternative grafting via thiol-yne click reaction between in-chain and chain-end alkyne-functionalized polymers.
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高影响因子
AMERICAN SOCIOLOGIST
·
2002
·Vol. 33
·期 3
·21-57
·
IF 0
Richardson Barbara
Best known as the first woman graduate from MIT, and the founder of Home Economics, Ellen Swallow Richards was a Progressive Era reformer who applied social science research techniques to problems of concern to early sociologists. As a mentor to many women who joined the “Cultural” and “Pragmatic” feminists of Hull House, her secular theories of “Oekology” and “Euthenics” challenged many of the models of social change prevalent in the Cambridge and Chicago academic communities. Her most radical contribution as a feminist was her assertion that women’s unpaid labor in the home played a vital economic role in maintaining capitalism and was the ultimate source of their second-class citizenship. She shared a belief in democracy and education as a feminist “Pragmatist,” and laid the groundwork for the contemporary “Ecofeminist” movement. Although she was a biochemist by training, she engaged several genera-tions of women in the application of scientific methods to the solution of contemporary social problems. As a political organizer, much of her legacy is reflected in the accomplishments of the reform organizations she was instrumental in founding.
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Nature Synthesis
·
2026
·
IF 22.6
Liu Zhexuan,Zhu Yifei,Yao Wenxuan,Song Yexin,Zhou Guangmin
The transition to green hydrogen is limited by the absence of efficient synthetic pathways for on-demand, high-purity hydrogen at decentralized locations. Most solar and wind resources are located far from demand centres, and the infrastructure costs of hydrogen pipelines make them economically unfeasible for widespread deployment. Here we report a reversible energy vector-mediated synthetic pathway that uses metallic zinc for hydrogen distribution. Machine learning-guided screening identified lactate as a ligand that outcompetes hydroxide for Zn(II) coordination in alkaline media, doubling the soluble Zn(II) concentration to 1.12 M and enabling self-sustained, circuit-free hydrogen production. The system operates between 0 and 80 °C with approximately 99% Faradaic efficiency and achieves a volumetric hydrogen capacity of 137.9 to 218.4 kg H 2 m −3 , exceeding, to the best of our knowledge, many established and state-of-the-art carriers. This approach offers improved safety and practical deployment compared with existing carriers, providing on-demand green hydrogen for remote communities, mobile platforms and off-grid industrial sites.
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高影响因子
危险品化学品经营许可证（带存储）