BioNanoScience
·
2026
·Vol. 16
·期 11
·689
·
IF 4
Muminova Kholida I.,Yunusov Khaydar E.,Mirkholisov Mirafzal M.,Goyibnazarov Ilkhom. Sh.,Atakhanov Abdumutolib A.,Baltaeva Mukhabbat M.,Shonakhunov Tulkin E.,Abdalkarim Somia Yassin Hussain,Yu Houyong,Jiang Guohua,Wan Yi,Niu Li‑Na,Chaiyasat Amorn
The present study focuses on the synthesis of silver nanoparticles (Ag NPs) via the chemical reduction of silver ions in hydroxypropylmethylcellulose (HPMC) solutions using ascorbic acid, followed by a systematic investigation of the rheological behavior of the resulting nanocomposite hydrogel. The physicochemical properties of the HPMC solution containing Ag NPs and the resulting nanofiber mats were characterized by Fourier-transform infrared spectroscopy (FTIR), UV–Vis spectroscopy, scanning electron microscopy (SEM), dynamic light scattering (DLS), and X-ray diffraction (XRD). SEM analysis revealed that the electrospun HPMC nanofibers obtained from the optimized 1% HPMC water–ethanol solution exhibited smooth surfaces and uniform morphology, with an optimal average fiber diameter of 670 ± 10 nm for nanofibers containing 37–76 nm Ag NPs, while increasing AgNO₃ concentration resulted in a gradual increase in nanofiber diameter. Microbiological studies demonstrated that nanofibers biomaterials obtained based on HPMC solutions containing Ag NPs with sizes of 37–76 nm exhibit strong antimicrobial activity against the Gram-positive bacteria Staphylococcus epidermidi s, Staphylococcus aureus , the Gram-negative bacteria Escherichia coli , Pseudomonas aeruginosa , and the fungal strain Candida albicans . The HPMC matrix provided sustained silver release, with cumulative Ag⁺ and Ag NP release reaching 83 ± 2% and 70 ± 2%, respectively, after 72 h. These findings indicate that HPMC/Ag NP-based nanofiber mat biomaterials with antimicrobial properties have significant potential for medical applications. Graphical
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JOURNAL OF NANOPARTICLE RESEARCH
·
2026
·Vol. 28
·期 11
·275
·
IF 3.5
Huang Liuci,Jiang Lipeng,Li Wenhao,Qin Guangping,Zhang Jianmin,Wang Ying,Tang Zhijiao,Wang Yumin
Proteolysis targeting chimera (PROTAC) technology had aroused considerable research interest in the past few decades. However, PROTAC technology still suffers some limitations such as unfavorable aqueous solubility, limited cell membrane permeability, poor tissue selectivity and adverse side effects. To advance its clinical translation, herein, a hyaluronic acid (HA)-encapsulated and GSH-responsive degradable dendritic mesoporous organosilicone nanoparticles was constructed as novel nanocarrier for enhanced delivery and controllable releasing of PROTAC within cancer cells. As a proof of concept, PROTAC ARV-771 is chosen and the DMONs-NH 2 @ARV-771@HA nanocomplex is prepared by step-by-step loading of ARV-771 and HA. The results showed that the DMONs-NH 2 @HA can specifically and efficiently transport cargo molecules into the tumor cells through CD44 receptor-mediated endocytosis. Moreover, the redox reaction with glutathione causes the breakup of DMONs-NH 2 and subsequent controllable release of ARV-771, enabling degradation of target protein BRD4 and selective therapy within tumor cells. The DMONs-NH 2 @HA nanoparticles only provide a novel delivery system for PROTAC but also may facilitate the clinical application of PROTAC in the near future.
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NATURE
·
2026
·Vol. 657
·期 8133
·918-924
·
IF 56.1
Xu Dongdong,Xiao Ke,Liu Ye,Luo Xin,Xu Jian,Wei Yikang,Ahmed Yameen,Yang Shuncheng,Liu Haonan,Wang Yinke,Huang Shun,Li Manya,Zhang Yuhong,Gao Han,Sun Hongfei,Duan Gongtao,Han Qiaolei,Liu Qiang,Zhang Shuo,Lv Xingjie,Jiang Jingfu,Li Chao,Liu Dongxue,Hao Min,Hou Xincheng,Saidaminov Makhsud I.,Tan Hairen
Environmentally sensitive ammonium halides have emerged as indispensable surface passivators for perovskite solar cells, demonstrating broadly effective performance at the laboratory scale 1 , 2 , 3 , 4 . However, the sensitivity of ammonium halides to humidity typically necessitates operation under an inert atmosphere 5 . Coupled with the heterogeneous distribution of passivators during large-area slot-die coating, applying such surface treatment techniques to the fabrication of metre-scale perovskite solar modules (PSMs) under ambient conditions remains challenging. Here we instead use chemically stable lead carboxylates as passivators on perovskite films engineered to have a naturally formed formamidinium iodide (FAI)-enriched surface by means of a high-saturated vapour pressure (SVP) solvent system (2-methoxyethanol (2-Me), 1,3-dioxolane (DOL) and dimethyl sulfoxide (DMSO)). By treating the tailored surface with lead dioleate (Pb(OA) 2 ) to enhance carrier transport and surface passivation, we fabricated PSMs that achieved certified efficiencies of 24.0% (aperture area of 810 cm 2 ) and 22.0% (total area 0.72 m 2 ) and passed all International Electrotechnical Commission (IEC) 61215 reliability tests. These results represent the highest reported performance for scalable, industrially viable perovskite photovoltaics (PVs).
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Nature Communications
·
2026
·Vol. 17
·期 1
·11053
·
IF 18.1
Wu Bo,Liu Xuejie,Zeng Zhiheng,Li Bolong,Fang Haoyu,Ho Derek
Piezoionics holds promise for self-powered bioelectronics, yet existing hydrogel and elastomer systems are often limited by poor biocompatibility, environmental instability, and low output. Here, we report a biocompatible deep eutectic solvent-polyvinyl alcohol (DES-PVA) eutectogel featuring a robust piezoionic response and practical wearable sensing capabilities. By incorporating a choline chloride-glycerol DES into a PVA network, we engineer tailored hydrogen bonds that selectively constrain choline cations while enabling rapid chloride anion transport, thereby amplifying the piezoionic response to achieve a sensitivity of 60 mV kPa –1 . In vitro assays verify the excellent biocompatibility of the eutectogel. Furthermore, practical application demonstrations underscore its capability for precise and continuous monitoring of diverse physiological signals, including pulse waveform and electrocardiograms (ECG), with fidelity comparable to commercial sensors. Overall, this work establishes a self-powered, bio-compliant epidermal platform for advanced iontronics and bioelectronics.
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Scientific Reports
·
2026
·
IF 4.9
Yu Nannan,Guo Gantong,Zhang Luyao,He Tao,Zhang Meng,Wang Jingting,Wang Jinfang,Yao Robin,Wang Guang-Li,Wang Jing
Acne vulgaris is a complex inflammatory disorder, and current treatment options are often limited by antibiotic resistance and cutaneous irritation, underscoring the urgent need for safer multi-target therapeutic alternatives. In this study, a novel antimicrobial cyclic peptide (AMCP) was systematically evaluated for its multidimensional anti-acne efficacy, and a penetration enhancer was developed for improving the topical dermal delivery. At a concentration of 20 µg/mL, AMCP inhibited dihydrotestosterone (DHT)- and linoleic acid (LA)-induced lipid synthesis in SZ95 sebocytes by 40.0% and 29.1%, respectively. Furthermore, it exhibited potent bactericidal activity against C. acnes (MIC or MBC at 0.5 µg/mL) and S. aureus (MIC or MBC at 1.0 µg/mL). AMCP suppressed key inflammatory mediators (IL-6, IL-8, IL-1β, TNF-α, and PGE₂) in a concentration-dependent manner in both HaCaT keratinocytes and SZ95 sebocytes. Additionally, it promoted keratinocyte migration, upregulated the expression of epidermal differentiation genes (FLG, IVL, Claudin-1, and KRT1), and downregulated KLK7 expression. Notably, the combination of 2% propylene glycol and 0.1% sodium surfactin synergistically enhanced topical dermal delivery of AMCP, resulting in a 5-fold increase in cumulative permeation at 8 h. In conclusion, AMCP exerts anti-acne effects through a multi-functional mechanism involving sebum control, antibacterial activity, anti-inflammation, and cell migration, while also overcoming the bottleneck of topical dermal delivery. These findings provide a new cyclic peptide with anti-acne efficacy, positioning AMCP as a promisingly anti-acne ingredient.
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CHINESE JOURNAL OF CATALYSIS
·
2019
·Vol. 40
·期 5
·631-637
·
IF 4.914
Zhenmin Xu,Ru Zheng,Yao Chen,Jian Zhu,Zhenfeng Bian
Ordered mesoporous Fe/TiO 2 was prepared by an evaporation-induced self-assembly method. The iron ions were in situ embedded in the pore wall of the TiO 2 framework. The catalyst has excellent light-assisted Fenton catalytic performance under UV and visible light irradiation. X-ray diffraction and transmission electron microscopy results showed that the TiO 2 samples have an ordered two-dimensional hexagonal pore structure and an anatase phase structure with high crystallinity . The ordered pore structure of the TiO 2 photocatalyst with a large specific surface area is beneficial to mass transfer and light harvesting. Furthermore, iron ions can be controlled by embedding them into the TiO 2 framework to prevent iron ion loss and inactivation. After five cycles, the reaction rate of the ordered mesoporous Fe/TiO 2 remained unchanged, indicating that the material has stable performance and broad application prospects for the purification of environmental pollutants .
研究领域:
材料科学
·
环境化学
·
催化化学
·
纳米科技
·
光化学
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NEW CARBON MATERIALS
·
2021
·Vol. 35
·期 6
·722-730
·
IF 1.905
Yuan-shuo Peng,Jian-xiao Yang,Kui Shi,Jian-guang Guo,Hui Zhu,Xuan-ke Li
The stabilization of isotropic pitch (IP)-derived pitch fibers (PFs) and mesophase pitch (MP)-derived PFsin air was performed at different heating rates and with different final stabilization temperatures. The stabilized fibers (SFs) and carbon fibers (CFs) were characterized by elemental analysis, FT-IR, TG-MS and SEM to investigate the influence of the degree of oxidation of the SFs on the microstructures and mechanical properties of the CFs. Results showed that a slow heating rate during stabilization was beneficial to the oxidative cross-linking of PFs, and the corresponding CFs had a higher carbonization yield and tensile strength at the lower heating rate. When both IPF and MPF were stabilized at 270 o C, the two resulting CFs all reached their optimal performance. In addition, the FTIR peak intensity ratio of the C=O band at about 1700 cm –1 to the C=C band at 1600 cm –1 of the SFs had a good relationship to the carbonization yield and tensile strength of the CFs, and thiscan beusedto optimize the degree of oxidation of the SFs. Moreover, insufficiently stabilized fibers released a great deal of H 2 and CH 4 , causing some porosity in the resulting CFs with a low tensile strength, especially forthe insufficiently stabilized IPCF. While over-stabilized fibers released a large amount of CO and CO 2 , causing cracked textures in the corresponding CFs, especially inthe over-stabilizedMPCF. Therefore, this research into the stabilization and carbonization behaviors of pitch fibers has great significance for improving the mechanical properties of pitch-based CFs.
研究领域:
材料科学
·
碳材料
·
高分子加工
·
热处理
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International Journal of Electrochemical Science
·
2023
·Vol. 8
·期 12
·12735-12740
·
IF 1.5
Binbin Zhang,Yuan Zhou,Xiang Li,Xiufeng Ren,Hongen Nian,Yue Shen,Qiang Yun
FTIR (Fourier transformed infrared) spectra have been collected and analyzed for solutions of lithium tetrafluoroborate in propylene carbonate (PC). It has been shown that the carbonyl stretch, symmetric ring deformation stretch and ring deformation stretch bands for PC is very sensitive to the interaction between Li + and the solvent molecule. Their half-peak breadth increases and bands split with the addition of LiBF 4 , indicating that a strong interaction exists between Li + and PC molecule mainly through the oxygen group of C=O and ring position of PC.
研究领域:
物理化学
·
光谱学
·
电解质溶液
·
电池材料
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NEW CARBON MATERIALS
·
2026
·Vol. 41
·期 3
·583-595
·
IF 7.2
Yunping Hu,Daixuan Gong,Meijie Qu,Ping Tang,Yuezhen Bin
A balance between electrical and magnetic properties is critical for electromagnetic shielding materials to achieve excellent electromagnetic interference (EMI) shielding and attenuation effectiveness across a broad frequency range. We have prepared free-standing buckypaper films (BPFP) decorated with Fe 3 O 4 particles and polyaniline (PANI) by a simple two-step method to meet this requirement. First, buckypaper films decorated with Fe 3 O 4 (BPF) were synthesized by the coprecipitation of Fe 2+ /Fe 3+ ions on buckypaper (BP) which was then coated with a polyaniline layer by the in situ polymerization of aniline monomers. Magnetic characterization revealed that the BPF and BPFP films had saturation magnetization ( M s ) values of 14.3 emu g −1 and 13.0 emu g −1 , respectively, confirming retention of the magnetic phase. The addition of Fe 3 O 4 nanoparticles and polyaniline to BP (30 μm) increased both the magnetic and dielectric losses due to the increased interfacial polarizations and anisotropy energy. 41 μm-thick BPF and BPFP films had an absorption-dominated shielding effectiveness of 35.1 dB and 36.4 dB, respectively, across the 5.85-18 GHz frequency band. These values are respectively 12.9% and 17.0% greater than that of pristine BP, highlighting the positive effect of Fe 3 O 4 -PANI heterostructures on electromagnetic wave dissipation. These films also had the tensile strength, flexibility, and lightness of BP, demonstrating exceptional promise for next-generation electromagnetic shielding materials.
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CHINESE JOURNAL OF CATALYSIS
·
2026
·
IF 17.2
Peiran Chen,Luo Cheng,Congbao Guo,Yu He,Yangyang Liu,Yi Wang,Shuqin Song
Efficient oxygen-evolving electrodes that can operate under high-current-density alkaline water/seawater electrolysis are essential for practical hydrogen production, yet the simultaneous achievement of high activity, chloride tolerance, and long-term durability remains difficult for non-precious-metal catalysts. In this work, a binder-free high-entropy layered double hydroxide electrode has been successfully constructed by directly growing multimetal LDH nanosheets on nickel foam through a facile one-step hydrothermal process. The optimized quinary LDH, composed of five non-noble transition metals, namely Fe, Ni, Co, Zn, and Cr, is denoted as CoNiFeZnCr LDH@NF. Benefiting from the high-entropy multimetal coordination environment, this electrode exhibits superior OER performance compared with the corresponding binary, ternary, and quaternary LDH counterparts. In alkaline seawater, CoNiFeZnCr LDH@NF requires a low OER overpotential of 250 mV to reach 100 mA cm −2 and shows a Tafel slope of 66.93 mV dec −1 . The electrode also maintains stable operation for 200 h at 100 mA cm −2 , indicating strong resistance to seawater-induced degradation. Density functional theory calculations further reveal that the quinary high-entropy configuration optimizes the adsorption behavior of *O intermediates and lowers the energy barrier of the rate-determining OER step. The improved activity and durability are therefore attributed to the synergistic electronic and structural effects arising from the incorporation of Fe, Ni, Co, Zn, and Cr into the LDH framework. This study demonstrates a practical high-entropy engineering strategy for developing robust non-precious-metal OER electrodes toward seawater-relevant hydrogen production.
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CHINESE JOURNAL OF CATALYSIS
·
2026
·
IF 17.2
Haifeng Fan,Di Xu,Ting Zeng,Guoqiang Hou,Yangyang Li,Siyi Huang,Yanfei Xu,Zheng Wang,Xinhua Gao,Xiang-Kui Gu,Mingyue Ding
CO 2 methanation technology has shown great application prospects in carbon neutrality and hydrogen storage due to its extremely high energy efficiency and potential economic benefits. It is highly desirable but challenging to design novel catalyst and achieve efficient and stable CO 2 methanation under mild conditions. Herein, we developed a highly active electron-enriched Y 2 O 3 /Ni catalyst, achieving a stable operation with ~80.1% CO 2 conversion and ~100% CH 4 selectivity for 400 h at 0.1 MPa and 220 °C, which was a 100 °C lower than the conventional supported Ni-based catalysts. Structural characterizations confirmed that the Y 2 O 3 /Ni catalyst maintained dynamic redox changes and formed electron-enriched Y 2 O 3– x -Ni interfaces under reaction conditions. Mechanism studies proved that the Y 2 O 3– x -Ni interfaces obviously lowered the energy barrier of *HCO dissociation, and shifted the rate-determining step from *HCO dissociation to *CO hydrogenation. Furthermore, profited by the moderate CO x adsorption ability and higher H 2 coverage at the Y 2 O 3– x -Ni interfaces, the *CO hydrogenation reaction was kinetically promoted. The above factors accounted for the excellent low-temperature CO 2 methanation activity of the Y 2 O 3 /Ni catalyst.
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TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
·
2026
·Vol. 36
·期 3
·988-999
·
IF 5.5
Qing-song LI,Bin YANG,Yang TIAN,Bao-qiang XU,Wen-long JIANG,Yuan GAO,Zong-kui JIANG
The modified molecular interaction volume model (M-MIVM) was used to calculate the activity values and their deviations from experimental data for Ag−Cu and Ag−Sb binary alloys. Subsequently, theoretical vapor−liquid equilibrium phase diagrams ( T − x − y and p − x − y ) were plotted via combining M-MIVM and vacuum theory. The vapor−liquid phase equilibrium (VLE) experiments were conducted on the Ag−Cu alloy at 1500−1560 K and 10−15 Pa and Ag−Sb alloys at 950−1350 K and 10 Pa. The results showed that the average relative deviation and average standard deviation of activity were lower than 5% and 0.02, respectively. A comparison of theoretical and experiment results for VLE revealed that the simulated data on the T − x − y diagram were well consistent with experimental values. Therefore, the VLE phase diagrams can serve as a guide in vacuum separation experiments and industrial production for Ag−Cu and Ag−Sb binary alloys.
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